Summary of project PR002460
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR002460. The data can be accessed directly via it's Project DOI: 10.21228/M8NR8D This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR002460 |
| Project DOI: | doi: 10.21228/M8NR8D |
| Project Title: | Muscle metabolome of young/age healthy/tumor bearing mice |
| Project Summary: | The goal of the study is to evaluate the metabolome differences in the muscles of young and aged mice when implanted with KPC cells (pancreatic cancer cells). We focused on the differential metabolite abundance between the young and the aged tumor bearing mice. We found histamine was significantly upregulated in the aged tumor-bearing mice. We followed this data and found a histamine signaling axis in cachexia. |
| Institute: | Indiana University School of Medicine |
| Last Name: | Doles |
| First Name: | Jason |
| Address: | 635 Barnhill Drive |
| Email: | jadoles@iu.edu |
| Phone: | 4027080332 |
Summary of all studies in project PR002460
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST003927 | Histidine decarboxylase inhibition attenuates cancer-associated muscle wasting | Mus musculus | Indiana University School of Medicine | MS | 2025-06-17 | 1 | 25 | Uploaded data (4.3M) |
