Summary of project PR002720
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR002720. The data can be accessed directly via it's Project DOI: 10.21228/M82N9G This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR002720 |
| Project DOI: | doi: 10.21228/M82N9G |
| Project Title: | Untargeted UHPLC-Q-Orbitrap Metabolomic Profiling of Cattle Serum after Testosterone Propionate Administration |
| Project Type: | Untargeted Metabolomics |
| Project Summary: | The misuse of anabolic androgenic steroids in livestock remains a major concern for food safety and regulatory monitoring, as exogenous administration of endogenous hormones such as testosterone is difficult to confirm using conventional analytical approaches. This project aimed to develop an untargeted metabolomics workflow based on ultra-high-performance liquid chromatography coupled to high-resolution Orbitrap mass spectrometry (UHPLC-Q-Orbitrap-MS) to investigate metabolic alterations in cattle serum following testosterone propionate administration. The study focused on optimizing data acquisition and processing strategies, including feature detection, alignment, and statistical evaluation using multivariate and univariate approaches. The resulting workflow provides a comprehensive analytical framework that can support future regulatory and research applications related to hormone misuse detection in food-producing animals. |
| Institute: | Universidade Federal de Minas Gerais |
| Department: | Department of Chemistry |
| Laboratory: | 261A |
| Last Name: | Rocha |
| First Name: | Diego |
| Address: | Av Antônio Carlos 6627, Belo Horizonte, MG, 31270-901, Brazil |
| Email: | diegogr.ufmg@gmail.com |
| Phone: | 553134095734 |
Summary of all studies in project PR002720
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST004304 | Untargeted UHPLC-Q-Orbitrap Metabolomic Profiling of Cattle Serum after Testosterone Propionate Administration | Bos taurus | Universidade Federal de Minas Gerais | MS* | 2025-11-12 | 1 | 60 | Uploaded data (3.1G)* |
