Summary of Study ST000329
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000264. The data can be accessed directly via it's Project DOI: 10.21228/M8NS3V This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Study ID | ST000329 |
| Study Title | Minimal change disease and focal segmental sclerosis in urine |
| Study Summary | This study will investigate if urine metabolomics can help understand the pathophysiology of glomerular diseases. |
| Institute | University of California, Davis |
| Department | Genome and Biomedical Sciences Facility |
| Laboratory | WCMC Metabolomics Core |
| Last Name | Fiehn |
| First Name | Oliver |
| Address | 1315 Genome and Biomedical Sciences Facility, 451 Health Sciences Drive, Davis, CA 95616 |
| ofiehn@ucdavis.edu | |
| Phone | (530) 754-8258 |
| Submit Date | 2015-02-12 |
| Num Groups | 6 |
| Total Subjects | 60 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | d |
| Analysis Type Detail | LC-MS |
| Release Date | 2016-01-27 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Project:
| Project ID: | PR000264 |
| Project DOI: | doi: 10.21228/M8NS3V |
| Project Title: | Minimal change disease and focal segmental sclerosis in urine |
| Project Summary: | This study will investigate if urine metabolomics can help understand the pathophysiology of glomerular diseases. |
| Institute: | University of California, Davis |
| Department: | Genome and Biomedical Sciences Facility |
| Laboratory: | WCMC Metabolomics Core |
| Last Name: | Fiehn |
| First Name: | Oliver |
| Address: | 1315 Genome and Biomedical Sciences Facility, 451 Health Sciences Drive, Davis, CA 95616 |
| Email: | ofiehn@ucdavis.edu |
| Phone: | (530) 754-8258 |
| Funding Source: | U24DK097154 |
Subject:
| Subject ID: | SU000349 |
| Subject Type: | Human |
| Subject Species: | Homo sapiens |
| Taxonomy ID: | 9606 |
| Species Group: | Mammals |
Factors:
Subject type: Human; Subject species: Homo sapiens (Factor headings shown in green)
| mb_sample_id | local_sample_id | Sample type |
|---|---|---|
| SA014783 | 26 | Control |
| SA014784 | 25 | Control |
| SA014785 | 23 | Control |
| SA014786 | 28 | Control |
| SA014787 | 24 | Control |
| SA014788 | 27 | Control |
| SA014789 | 32 | Control |
| SA014790 | 30 | Control |
| SA014791 | 31 | Control |
| SA014792 | 29 | Control |
| SA014793 | 19 | FSGS |
| SA014794 | 20 | FSGS |
| SA014795 | 22 | FSGS |
| SA014796 | 18 | FSGS |
| SA014797 | 17 | FSGS |
| SA014798 | 14 | FSGS |
| SA014799 | 15 | FSGS |
| SA014800 | 13 | FSGS |
| SA014801 | 16 | FSGS |
| SA014802 | 6 | MCD |
| SA014803 | 5 | MCD |
| SA014804 | 3 | MCD |
| SA014805 | 7 | MCD |
| SA014806 | 4 | MCD |
| SA014807 | 10 | MCD |
| SA014808 | 12 | MCD |
| SA014809 | 11 | MCD |
| SA014810 | 2 | MCD |
| SA014811 | 9 | MCD |
| SA014812 | 8 | MCD |
| Showing results 1 to 30 of 30 |
Collection:
| Collection ID: | CO000343 |
| Collection Summary: | - |
| Sample Type: | Urine |
Treatment:
| Treatment ID: | TR000363 |
| Treatment Summary: | There are 12 patient urines with minimal change disease (MCD), 9 patient urines with focal segmental sclerosis (FSGS), and 10 urines from healthy controls |
| Treatment Protocol Filename: | StudyDesign-ElifErkan-102414.pdf |
Sample Preparation:
| Sampleprep ID: | SP000357 |
| Sampleprep Summary: | - |
| Sampleprep Protocol Filename: |
Chromatography:
| Chromatography ID: | CH000367 |
| Chromatography Summary: | UPLC |
| Methods Filename: | Data_Dictionary_Fiehn_laboratory_CSH_QTOF_lipidomics_05-29-2014.pdf |
| Instrument Name: | Unspecified |
| Column Name: | Waters Acquity CSH C18 (100 x 2.1mm,1.7um) |
| Column Pressure: | 450-850 bar |
| Column Temperature: | 65 C |
| Flow Gradient: | 15% B to 99% B |
| Flow Rate: | 0.6 mL/min |
| Internal Standard: | See data dictionary |
| Retention Time: | See data dictionary |
| Sample Injection: | 1.67 uL |
| Solvent A: | 60% acetonitrile/40% water; 10mM formic acid; 10mM ammonium formate |
| Solvent B: | 90% isopropanol/10% acetonitrile; 10mM formic acid; 10mM ammonium formate |
| Analytical Time: | 13 min |
| Capillary Voltage: | 3500 |
| Time Program: | 15 min |
| Weak Wash Solvent Name: | Isopropanol |
| Weak Wash Volume: | 5 seconds |
| Strong Wash Solvent Name: | Isopropanol |
| Target Sample Temperature: | Autosampler temp 4 C |
| Randomization Order: | Excel |
| Chromatography Type: | Reversed phase |
Analysis:
| Analysis ID: | AN000525 |
| Laboratory Name: | WCMC Metabolomics Core |
| Analysis Type: | MS |
| Instrument Name: | Agilent 6530 QTOF |
| Software Version: | MassHunter |
| Detector Type: | TOF MCP |
| Data Format: | .d |
| Chromatography ID: | CH000367 |
| Num Factors: | 3 |
| Num Metabolites: | 222 |
| Rt Units: | Minutes |
| Units: | Peak height |
| Analysis ID: | AN000526 |
| Laboratory Name: | WCMC Metabolomics Core |
| Analysis Type: | MS |
| Instrument Name: | Agilent 6530 QTOF |
| Software Version: | MassHunter |
| Detector Type: | TOF MCP |
| Data Format: | .d |
| Chromatography ID: | CH000367 |
| Num Factors: | 3 |
| Num Metabolites: | 136 |
| Rt Units: | Minutes |
| Units: | Peak height |