Summary of Study ST000705
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000502. The data can be accessed directly via it's Project DOI: 10.21228/M8S37Q This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST000705 |
| Study Title | Slow Aging Mice Plasma Metabolomics |
| Study Type | MS analysis |
| Study Summary | Plasma from young adult mice, fasted 4 hr prior to bleeding. Key comparisons: Snell dwarf vs Snell normal. GHRKO KO vs WT. PAPPA KO vs Het. And two factor ANOVA: LivGHR KO, LivGHR WT vs GHRKO and GHRWT. Consistency between Snell, GHRKO, and PAPPA will be a major theme in the analysis. |
| Institute | University of Michigan |
| Department | Biomedical Research Core Facilities |
| Laboratory | Metabolomics core |
| Last Name | Kachman |
| First Name | Maureen |
| Address | 6300 Brehm Tower, 1000 Wall Street, Ann Arbor, MI 48105-5714 |
| mkachman@med.umich.edu | |
| Phone | (734) 232-8175 |
| Submit Date | 2017-06-19 |
| Num Groups | 14 |
| Total Subjects | 17 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | d |
| Analysis Type Detail | LC-MS |
| Release Date | 2017-12-06 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Project:
| Project ID: | PR000502 |
| Project DOI: | doi: 10.21228/M8S37Q |
| Project Title: | Slow Aging Mice Studies |
| Project Type: | MS analysis |
| Project Summary: | Plasma from slow-aging mice |
| Institute: | University of Michigan |
| Department: | Pathology |
| Laboratory: | Miller Lab |
| Last Name: | Miller |
| First Name: | Richard |
| Address: | University Michigan, 2900 Huron Parkway, Ann Arbor, MI 48105 |
| Email: | millerr@umich.edu |
| Phone: | 734-936-2122 |
Subject:
| Subject ID: | SU000728 |
| Subject Type: | Mouse |
| Subject Species: | Mus musculus |
| Taxonomy ID: | 10090 |
| Species Group: | Mammals |
Factors:
Subject type: Mouse; Subject species: Mus musculus (Factor headings shown in green)
| mb_sample_id | local_sample_id | Genotype | Sex | Strain |
|---|---|---|---|---|
| SA039779 | S00019810 | Dwarf | F | Snell |
| SA039780 | S00019806 | Dwarf | F | Snell |
| SA039781 | S00019804 | Dwarf | F | Snell |
| SA039782 | S00019818 | Dwarf | F | Snell |
| SA039783 | S00019816 | Dwarf | F | Snell |
| SA039784 | S00019800 | Dwarf | F | Snell |
| SA039785 | S00019802 | Dwarf | F | Snell |
| SA039786 | S00019808 | Dwarf | F | Snell |
| SA039787 | S00019822 | Dwarf | M | Snell |
| SA039788 | S00019824 | Dwarf | M | Snell |
| SA039789 | S00019814 | Dwarf | M | Snell |
| SA039790 | S00019820 | Dwarf | M | Snell |
| SA039791 | S00019812 | Dwarf | M | Snell |
| SA039792 | S00019826 | Dwarf | M | Snell |
| SA039793 | S00019895 | Het | F | PappA |
| SA039794 | S00019909 | Het | F | PappA |
| SA039795 | S00019896 | Het | F | PappA |
| SA039796 | S00019905 | Het | F | PappA |
| SA039797 | S00019885 | Het | F | PappA |
| SA039798 | S00019884 | Het | F | PappA |
| SA039799 | S00019907 | Het | F | PappA |
| SA039800 | S00019903 | Het | F | PappA |
| SA039801 | S00019893 | Het | M | PappA |
| SA039802 | S00019891 | Het | M | PappA |
| SA039803 | S00019888 | Het | M | PappA |
| SA039804 | S00019889 | Het | M | PappA |
| SA039805 | S00019901 | Het | M | PappA |
| SA039806 | S00019899 | Het | M | PappA |
| SA039807 | S00019846 | KO | F | GHRKO Global |
| SA039808 | S00019836 | KO | F | GHRKO Global |
| SA039809 | S00019838 | KO | F | GHRKO Global |
| SA039810 | S00019850 | KO | F | GHRKO Global |
| SA039811 | S00019852 | KO | F | GHRKO Global |
| SA039812 | S00019829 | KO | F | GHRKO Global |
| SA039813 | S00019844 | KO | F | GHRKO Global |
| SA039814 | S00019830 | KO | F | GHRKO Global |
| SA039815 | S00019906 | KO | F | PappA |
| SA039816 | S00019908 | KO | F | PappA |
| SA039817 | S00019910 | KO | F | PappA |
| SA039818 | S00019887 | KO | F | PappA |
| SA039819 | S00019886 | KO | F | PappA |
| SA039820 | S00019904 | KO | F | PappA |
| SA039821 | S00019897 | KO | F | PappA |
| SA039822 | S00019898 | KO | F | PappA |
| SA039823 | S00019847 | KO | M | GHRKO Global |
| SA039824 | S00019832 | KO | M | GHRKO Global |
| SA039825 | S00019839 | KO | M | GHRKO Global |
| SA039826 | S00019828 | KO | M | GHRKO Global |
| SA039827 | S00019840 | KO | M | GHRKO Global |
| SA039828 | S00019843 | KO | M | GHRKO Global |
| SA039829 | S00019900 | KO | M | PappA |
| SA039830 | S00019902 | KO | M | PappA |
| SA039831 | S00019890 | KO | M | PappA |
| SA039832 | S00019883 | KO | M | PappA |
| SA039833 | S00019894 | KO | M | PappA |
| SA039834 | S00019892 | KO | M | PappA |
| SA039835 | S00019871 | Neg | F | Liver GHRKO |
| SA039836 | S00019870 | Neg | F | Liver GHRKO |
| SA039837 | S00019869 | Neg | F | Liver GHRKO |
| SA039838 | S00019878 | Neg | F | Liver GHRKO |
| SA039839 | S00019860 | Neg | F | Liver GHRKO |
| SA039840 | S00019880 | Neg | F | Liver GHRKO |
| SA039841 | S00019882 | Neg | F | Liver GHRKO |
| SA039842 | S00019859 | Neg | F | Liver GHRKO |
| SA039843 | S00019874 | Neg | M | Liver GHRKO |
| SA039844 | S00019875 | Neg | M | Liver GHRKO |
| SA039845 | S00019867 | Neg | M | Liver GHRKO |
| SA039846 | S00019855 | Neg | M | Liver GHRKO |
| SA039847 | S00019866 | Neg | M | Liver GHRKO |
| SA039848 | S00019856 | Neg | M | Liver GHRKO |
| SA039849 | S00019805 | Normal | F | Snell |
| SA039850 | S00019803 | Normal | F | Snell |
| SA039851 | S00019807 | Normal | F | Snell |
| SA039852 | S00019809 | Normal | F | Snell |
| SA039853 | S00019817 | Normal | F | Snell |
| SA039854 | S00019815 | Normal | F | Snell |
| SA039855 | S00019801 | Normal | F | Snell |
| SA039856 | S00019799 | Normal | F | Snell |
| SA039857 | S00019813 | Normal | M | Snell |
| SA039858 | S00019811 | Normal | M | Snell |
| SA039859 | S00019825 | Normal | M | Snell |
| SA039860 | S00019819 | Normal | M | Snell |
| SA039861 | S00019823 | Normal | M | Snell |
| SA039862 | S00019821 | Normal | M | Snell |
| SA039863 | S00020157 | Pooled plasma | Pooled plasma | Pooled plasma |
| SA039864 | S00019868 | Pos | F | Liver GHRKO |
| SA039865 | S00019872 | Pos | F | Liver GHRKO |
| SA039866 | S00019863 | Pos | F | Liver GHRKO |
| SA039867 | S00019862 | Pos | F | Liver GHRKO |
| SA039868 | S00019877 | Pos | F | Liver GHRKO |
| SA039869 | S00019881 | Pos | F | Liver GHRKO |
| SA039870 | S00019879 | Pos | F | Liver GHRKO |
| SA039871 | S00019861 | Pos | F | Liver GHRKO |
| SA039872 | S00019858 | Pos | M | Liver GHRKO |
| SA039873 | S00019864 | Pos | M | Liver GHRKO |
| SA039874 | S00019865 | Pos | M | Liver GHRKO |
| SA039875 | S00019876 | Pos | M | Liver GHRKO |
| SA039876 | S00019873 | Pos | M | Liver GHRKO |
| SA039877 | S00019857 | Pos | M | Liver GHRKO |
| SA039878 | S00019845 | WT | F | GHRKO Global |
Collection:
| Collection ID: | CO000722 |
| Collection Summary: | - |
| Sample Type: | Blood |
Treatment:
| Treatment ID: | TR000742 |
| Treatment Summary: | - |
Sample Preparation:
| Sampleprep ID: | SP000735 |
| Sampleprep Summary: | - |
| Sampleprep Protocol Filename: | A003_-_Untargeted_Metabolomics.pdf |
Chromatography:
| Chromatography ID: | CH000770 |
| Instrument Name: | Agilent |
| Column Name: | Waters Acquity HSS T3 (50 x 2.1mm,1.8um) |
| Chromatography Type: | Reversed phase |
Analysis:
| Analysis ID: | AN001095 |
| Analysis Type: | MS |
| Analysis Protocol File: | A003_-_Untargeted_Metabolomics.pdf |
| Instrument Name: | 6530 Q-TOF LC/MS (Agilent) |
| Chromatography ID: | CH000770 |
| Num Factors: | 17 |
| Num Metabolites: | 74 |
| Has Mz: | 1 |
| Has Rt: | 1 |
| Rt Units: | Minutes |
| Units: | peak area normalized |
| Analysis ID: | AN001096 |
| Analysis Type: | MS |
| Analysis Protocol File: | A003_-_Untargeted_Metabolomics.pdf |
| Instrument Name: | 6530 Q-TOF LC/MS (Agilent) |
| Chromatography ID: | CH000770 |
| Num Factors: | 17 |
| Num Metabolites: | 61 |
| Has Mz: | 1 |
| Has Rt: | 1 |
| Rt Units: | Minutes |
| Units: | peak area normalized |
