Summary of Study ST000705

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR000502. The data can be accessed directly via it's Project DOI: 10.21228/M8S37Q This work is supported by NIH grant, U2C- DK119886.


This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST000705
Study TitleSlow Aging Mice Plasma Metabolomics
Study TypeMS analysis
Study SummaryPlasma from young adult mice, fasted 4 hr prior to bleeding. Key comparisons: Snell dwarf vs Snell normal. GHRKO KO vs WT. PAPPA KO vs Het. And two factor ANOVA: LivGHR KO, LivGHR WT vs GHRKO and GHRWT. Consistency between Snell, GHRKO, and PAPPA will be a major theme in the analysis.
University of Michigan
DepartmentBiomedical Research Core Facilities
LaboratoryMetabolomics core
Last NameKachman
First NameMaureen
Address6300 Brehm Tower, 1000 Wall Street, Ann Arbor, MI 48105-5714
Phone(734) 232-8175
Submit Date2017-06-19
Num Groups14
Total Subjects17
Raw Data AvailableYes
Raw Data File Type(s)d
Analysis Type DetailLC-MS
Release Date2017-12-06
Release Version1
Maureen Kachman Maureen Kachman application/zip

Select appropriate tab below to view additional metadata details:


Project ID:PR000502
Project DOI:doi: 10.21228/M8S37Q
Project Title:Slow Aging Mice Studies
Project Type:MS analysis
Project Summary:Plasma from slow-aging mice
Institute:University of Michigan
Laboratory:Miller Lab
Last Name:Miller
First Name:Richard
Address:University Michigan, 2900 Huron Parkway, Ann Arbor, MI 48105


Subject ID:SU000728
Subject Type:Mouse
Subject Species:Mus musculus
Taxonomy ID:10090
Species Group:Mammal


Subject type: Mouse; Subject species: Mus musculus (Factor headings shown in green)

mb_sample_id local_sample_id Genotype Sex Strain
SA039779S00019810Dwarf F Snell
SA039780S00019806Dwarf F Snell
SA039781S00019804Dwarf F Snell
SA039782S00019818Dwarf F Snell
SA039783S00019816Dwarf F Snell
SA039784S00019800Dwarf F Snell
SA039785S00019802Dwarf F Snell
SA039786S00019808Dwarf F Snell
SA039787S00019822Dwarf M Snell
SA039788S00019824Dwarf M Snell
SA039789S00019814Dwarf M Snell
SA039790S00019820Dwarf M Snell
SA039791S00019812Dwarf M Snell
SA039792S00019826Dwarf M Snell
SA039793S00019895Het F PappA
SA039794S00019909Het F PappA
SA039795S00019896Het F PappA
SA039796S00019905Het F PappA
SA039797S00019885Het F PappA
SA039798S00019884Het F PappA
SA039799S00019907Het F PappA
SA039800S00019903Het F PappA
SA039801S00019893Het M PappA
SA039802S00019891Het M PappA
SA039803S00019888Het M PappA
SA039804S00019889Het M PappA
SA039805S00019901Het M PappA
SA039806S00019899Het M PappA
SA039807S00019846KO F GHRKO Global
SA039808S00019836KO F GHRKO Global
SA039809S00019838KO F GHRKO Global
SA039810S00019850KO F GHRKO Global
SA039811S00019852KO F GHRKO Global
SA039812S00019829KO F GHRKO Global
SA039813S00019844KO F GHRKO Global
SA039814S00019830KO F GHRKO Global
SA039815S00019906KO F PappA
SA039816S00019908KO F PappA
SA039817S00019910KO F PappA
SA039818S00019887KO F PappA
SA039819S00019886KO F PappA
SA039820S00019904KO F PappA
SA039821S00019897KO F PappA
SA039822S00019898KO F PappA
SA039823S00019847KO M GHRKO Global
SA039824S00019832KO M GHRKO Global
SA039825S00019839KO M GHRKO Global
SA039826S00019828KO M GHRKO Global
SA039827S00019840KO M GHRKO Global
SA039828S00019843KO M GHRKO Global
SA039829S00019900KO M PappA
SA039830S00019902KO M PappA
SA039831S00019890KO M PappA
SA039832S00019883KO M PappA
SA039833S00019894KO M PappA
SA039834S00019892KO M PappA
SA039835S00019871Neg F Liver GHRKO
SA039836S00019870Neg F Liver GHRKO
SA039837S00019869Neg F Liver GHRKO
SA039838S00019878Neg F Liver GHRKO
SA039839S00019860Neg F Liver GHRKO
SA039840S00019880Neg F Liver GHRKO
SA039841S00019882Neg F Liver GHRKO
SA039842S00019859Neg F Liver GHRKO
SA039843S00019874Neg M Liver GHRKO
SA039844S00019875Neg M Liver GHRKO
SA039845S00019867Neg M Liver GHRKO
SA039846S00019855Neg M Liver GHRKO
SA039847S00019866Neg M Liver GHRKO
SA039848S00019856Neg M Liver GHRKO
SA039849S00019805Normal F Snell
SA039850S00019803Normal F Snell
SA039851S00019807Normal F Snell
SA039852S00019809Normal F Snell
SA039853S00019817Normal F Snell
SA039854S00019815Normal F Snell
SA039855S00019801Normal F Snell
SA039856S00019799Normal F Snell
SA039857S00019813Normal M Snell
SA039858S00019811Normal M Snell
SA039859S00019825Normal M Snell
SA039860S00019819Normal M Snell
SA039861S00019823Normal M Snell
SA039862S00019821Normal M Snell
SA039863S00020157Pooled plasma Pooled plasma Pooled plasma
SA039864S00019868Pos F Liver GHRKO
SA039865S00019872Pos F Liver GHRKO
SA039866S00019863Pos F Liver GHRKO
SA039867S00019862Pos F Liver GHRKO
SA039868S00019877Pos F Liver GHRKO
SA039869S00019881Pos F Liver GHRKO
SA039870S00019879Pos F Liver GHRKO
SA039871S00019861Pos F Liver GHRKO
SA039872S00019858Pos M Liver GHRKO
SA039873S00019864Pos M Liver GHRKO
SA039874S00019865Pos M Liver GHRKO
SA039875S00019876Pos M Liver GHRKO
SA039876S00019873Pos M Liver GHRKO
SA039877S00019857Pos M Liver GHRKO
SA039878S00019845WT F GHRKO Global
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Collection ID:CO000722
Collection Summary:-
Sample Type:Blood


Treatment ID:TR000742
Treatment Summary:-

Sample Preparation:

Sampleprep ID:SP000735
Sampleprep Summary:-
Sampleprep Protocol Filename:A003_-_Untargeted_Metabolomics.pdf

Combined analysis:

Analysis ID AN001095 AN001096
Analysis type MS MS
Chromatography type Reversed phase Reversed phase
Chromatography system Agilent Agilent
Column Waters Acquity HSS T3 (50 x 2.1mm,1.8um) Waters Acquity HSS T3 (50 x 2.1mm,1.8um)
MS instrument type QTOF QTOF
MS instrument name Agilent 6530 QTOF Agilent 6530 QTOF
Units peak area normalized peak area normalized


Chromatography ID:CH000770
Instrument Name:Agilent
Column Name:Waters Acquity HSS T3 (50 x 2.1mm,1.8um)
Chromatography Type:Reversed phase


MS ID:MS000990
Analysis ID:AN001095
Instrument Name:Agilent 6530 QTOF
Instrument Type:QTOF
Analysis Protocol File:A003_-_Untargeted_Metabolomics.pdf
MS ID:MS000991
Analysis ID:AN001096
Instrument Name:Agilent 6530 QTOF
Instrument Type:QTOF
Analysis Protocol File:A003_-_Untargeted_Metabolomics.pdf