Summary of Study ST000751

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000541. The data can be accessed directly via it's Project DOI: 10.21228/M8R08R This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST000751
Study TitleMouse placentas-DEHP exposure
Study TypeMS analysis
Study SummaryPregnant mice were treated for 14 days (from GD 0.5-13.5) with 125mg/kg/day DEHP or vehicle control (corn oil) via oral gavage. After the last treatment, mice were euthanized and placenta were removed and flash frozen in liquid nitrogen. Placentas were then stored at -80 celsius.
Institute
University of Michigan
DepartmentBiomedical Research Core Facilities
LaboratoryMetabolomics core
Last NameKachman
First NameMaureen
Address6300 Brehm Tower, 1000 Wall Street, Ann Arbor, MI 48105-5714
Emailmkachman@med.umich.edu
Phone(734) 232-8175
Submit Date2017-06-19
Num Groups2
Total Subjects13
Raw Data AvailableYes
Raw Data File Type(s)d
Analysis Type DetailLC-MS
Release Date2017-12-06
Release Version1
Maureen Kachman Maureen Kachman
https://dx.doi.org/10.21228/M8R08R
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

Select appropriate tab below to view additional metadata details:

Project:

Project ID:PR000541
Project DOI:doi: 10.21228/M8R08R
Project Title:Mouse placentas-DEHP exposure
Project Type:MS analysis
Project Summary:Pregnant mice were treated with DEHP or vehicle control and placenta were removed for metabolomics analysis
Institute:University of Michigan
Department:Environmental Health
Laboratory:Loch-Caruso Lab
Last Name:Loch-Caruso
First Name:Rita
Address:Ann Arbor, MI
Email:rlc@umich.edu
Phone:734-936-1256

Subject:

Subject ID:SU000774
Subject Type:Mouse
Subject Species:Mus musculus
Taxonomy ID:10090
Species Group:Mammal

Factors:

Subject type: Mouse; Subject species: Mus musculus (Factor headings shown in green)

mb_sample_id local_sample_id Treatment
SA041454S00028209Control
SA041455S00028203Control
SA041456S00028207Control
SA041457S00028208Control
SA041458S00028204Control
SA041459S00028205Control
SA041460S00028206Control
SA041461S00028215DEHP
SA041462S00028216DEHP
SA041463S00028214DEHP
SA041464S00028210DEHP
SA041465S00028211DEHP
SA041466S00028212DEHP
SA041467S00028213DEHP
Showing results 1 to 14 of 14

Collection:

Collection ID:CO000768
Collection Summary:-
Sample Type:Placenta

Treatment:

Treatment ID:TR000788
Treatment Summary:-

Sample Preparation:

Sampleprep ID:SP000781
Sampleprep Summary:-
Sampleprep Protocol Filename:A003_-_Untargeted_Metabolomics.pdf

Combined analysis:

Analysis ID AN001178 AN001179
Analysis type MS MS
Chromatography type Reversed phase Reversed phase
Chromatography system Agilent Agilent
Column Waters Acquity HSS T3 (50 x 2.1mm,1.8um) Waters Acquity HSS T3 (50 x 2.1mm,1.8um)
MS Type ESI ESI
MS instrument type QTOF QTOF
MS instrument name Agilent 6530 QTOF Agilent 6530 QTOF
Ion Mode NEGATIVE POSITIVE
Units peak area peak area

Chromatography:

Chromatography ID:CH000827
Instrument Name:Agilent
Column Name:Waters Acquity HSS T3 (50 x 2.1mm,1.8um)
Chromatography Type:Reversed phase

MS:

MS ID:MS001073
Analysis ID:AN001178
Instrument Name:Agilent 6530 QTOF
Instrument Type:QTOF
MS Type:ESI
Ion Mode:NEGATIVE
Analysis Protocol File:A003_-_Untargeted_Metabolomics.pdf
  
MS ID:MS001074
Analysis ID:AN001179
Instrument Name:Agilent 6530 QTOF
Instrument Type:QTOF
MS Type:ESI
Ion Mode:POSITIVE
Analysis Protocol File:A003_-_Untargeted_Metabolomics.pdf
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