Summary of Study ST000762

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR000550. The data can be accessed directly via it's Project DOI: 10.21228/M8K96J This work is supported by NIH grant, U2C- DK119886.


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Study IDST000762
Study TitlePlasma Nucleotide/adenosine concentrations in patiens with scleroderma depending on exercise
Study TypeMS analysis
Study SummaryThis experiment was performed using the following cohorts: 1) healthy controls, 2) patients with scleroderma at low risk for pulmonary hypertension, 3) pateints with scleroderma at high risk for pulmonary hypertension (SSc Cath). Whole blood was drawn directly into stop soilution (1:1 ratio) at rest and again at peak exercise for each human subject. The samples were processed to plasma by MCRU and stored at -80 in the Biorepository.
University of Michigan
DepartmentBiomedical Research Core Facilities
LaboratoryMetabolomics core
Last NameKachman
First NameMaureen
Address6300 Brehm Tower, 1000 Wall Street, Ann Arbor, MI 48105-5714
Phone(734) 232-8175
Submit Date2017-06-19
Num Groups5
Total Subjects26
Raw Data AvailableYes
Raw Data File Type(s)d
Analysis Type DetailLC-MS
Release Date2017-12-06
Release Version1
Maureen Kachman Maureen Kachman application/zip

Select appropriate tab below to view additional metadata details:


Project ID:PR000550
Project DOI:doi: 10.21228/M8K96J
Project Title:Scleroderma and exercise
Project Type:MS analysis
Project Summary:Plasma Nucleotide/adenosine concentrations in patiens with scleroderma depending on exercise
Institute:University of Michigan
Department:Internal Medicine-Cardiology
Laboratory:Visovatti Lab
Last Name:Visovatti
First Name:Scott
Address:Ann Arbor, MI


Subject ID:SU000785
Subject Type:Human
Subject Species:Homo sapiens
Taxonomy ID:9606
Species Group:Human


Subject type: Human; Subject species: Homo sapiens (Factor headings shown in green)

mb_sample_id local_sample_id Exercise Group
SA041720S00019114No Healthy
SA041721S00019110No Healthy
SA041722S00019108No Healthy
SA041723S00019118No Healthy
SA041724S00019120No Healthy
SA041725S00019138No Healthy
SA041726S00019132No Healthy
SA041727S00019106No Healthy
SA041728S00019116No Healthy
SA041729S00019093No Low Risk SSc
SA041730S00019112No Low Risk SSc
SA041731S00019122No Low Risk SSc
SA041732S00019130No Low Risk SSc
SA041733S00019097No Low Risk SSc
SA041734S00019091No Low Risk SSc
SA041735S00019124No SSc Cath
SA041736S00019128No SSc Cath
SA041737S00019126No SSc Cath
SA041738S00019134No SSc Cath
SA041739S00019103No SSc Cath
SA041740S00019140No SSc Cath
SA041741S00019101No SSc Cath
SA041742S00019105No SSc Cath
SA041743S00019099No SSc Cath
SA041744S00019136No SSc Cath
SA041745S00019095No SSc Cath
SA041746S00019133Yes Healthy
SA041747S00019139Yes Healthy
SA041748S00019121Yes Healthy
SA041749S00019115Yes Healthy
SA041750S00019119Yes Healthy
SA041751S00019111Yes Healthy
SA041752S00019109Yes Healthy
SA041753S00019117Yes Healthy
SA041754S00019107Yes Healthy
SA041755S00019092Yes Low Risk SSc
SA041756S00019098Yes Low Risk SSc
SA041757S00019094Yes Low Risk SSc
SA041758S00019131Yes Low Risk SSc
SA041759S00019113Yes Low Risk SSc
SA041760S00019123Yes Low Risk SSc
SA041761S00019104Yes SSc Cath
SA041762S00019102Yes SSc Cath
SA041763S00019141Yes SSc Cath
SA041764S00019096Yes SSc Cath
SA041765S00019100Yes SSc Cath
SA041766S00019137Yes SSc Cath
SA041767S00019125Yes SSc Cath
SA041768S00019135Yes SSc Cath
SA041769S00019129Yes SSc Cath
SA041770S00019127Yes SSc Cath
Showing results 1 to 51 of 51


Collection ID:CO000779
Collection Summary:-
Sample Type:Blood


Treatment ID:TR000799
Treatment Summary:-

Sample Preparation:

Sampleprep ID:SP000792
Sampleprep Summary:-
Sampleprep Protocol Filename:A011_-_Glycolysis-TCA-nucleotides.pdf

Combined analysis:

Analysis ID AN001200
Analysis type MS
Chromatography type HILIC
Chromatography system Agilent
Column Phenomenex Luna NH2 (150 x 1mm,3um)
MS instrument type QTOF
MS instrument name Agilent 6520B QTOF
Units nM


Chromatography ID:CH000841
Instrument Name:Agilent
Column Name:Phenomenex Luna NH2 (150 x 1mm,3um)
Flow Rate:0.075 mL/min
Solvent A:100% water; 5 mM ammonium acetate, pH 9.9
Solvent B:100% acetonitrile
Chromatography Type:HILIC


MS ID:MS001095
Analysis ID:AN001200
Instrument Name:Agilent 6520B QTOF
Instrument Type:QTOF
Analysis Protocol File:A011_-_Glycolysis-TCA-nucleotides.pdf