Summary of study ST000814

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000579. The data can be accessed directly via it's Project DOI: 10.21228/M8TM29 This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST000814
Study TitleHormones & Cognition/Aging/Placebo
Study TypeMS analysis
Study SummaryThe goal is to look at measures of overall metabolic state in relationship to hormonal environment and measures of mood/depression or cognitive function (behavioral and functional MRI images). There are some relationships in this data set between glucose/insulin levels and cognitive function, and we would like to use the untargeted assays to further investigate this relationship. Factors related to visual/spatial memory are included in the design. Factors 1 and 2 (Left Hippocampus, Right Hippocampus) are levels of activation in the hippocampus during a visual memory task, (data missing for some of the samples). Factors 3-5 (BVMT % Retained, BVMT Learning T, BVMT Delay T) are results from a cognitive test of spatial memory function.
Institute
University of Michigan
DepartmentBiomedical Research Core Facilities
LaboratoryMetabolomics core
Last NameKachman
First NameMaureen
Address6300 Brehm Tower, 1000 Wall Street, Ann Arbor, MI 48105-5714
Emailmkachman@med.umich.edu
Phone(734) 232-8175
Submit Date2017-07-13
Num Groups72
Total Subjects28
Raw Data AvailableYes
Raw Data File Type(s).d
Analysis Type DetailLC-MS
Release Date2017-10-11
Release Version1
Maureen Kachman Maureen Kachman
https://dx.doi.org/10.21228/M8TM29
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

Select appropriate tab below to view additional metadata details:


Project:

Project ID:PR000579
Project DOI:doi: 10.21228/M8TM29
Project Title:Hormones & Cognition/Aging
Project Type:MS analysis
Project Summary:Untargeted metabolomic assay of early menopause
Institute:University of Michigan
Department:Psychiatry
Laboratory:Berent-Spillson Lab
Last Name:Berent-Spillson
First Name:Alison
Address:Ann Arbor, MI
Email:berent@umich.edu
Phone:734-717-6399

Subject:

Subject ID:SU000840
Subject Type:HUMAN
Subject Species:Homo sapiens
Taxonomy ID:9606
Species Group:Human

Factors:

Subject type: HUMAN; Subject species: Homo sapiens (Factor headings shown in green)

mb_sample_id local_sample_id Factor
SA045134S00014759data
SA045135S00014760data
SA045136S00014758data
SA045137S00014757data
SA045138S00014756data
SA045139S00014761data
SA045140S00014763data
SA045141S00014766data
SA045142S00020133data
SA045143S00014765data
SA045144S00014764data
SA045145S00014755data
SA045146S00014762data
SA045147S00014754data
SA045148S00014745data
SA045149S00014746data
SA045150S00014744data
SA045151S00014743data
SA045152S00014741data
SA045153S00014742data
SA045154S00014747data
SA045155S00014748data
SA045156S00014752data
SA045157S00014753data
SA045158S00014751data
SA045159S00014750data
SA045160S00014749data
SA045161S00014740data
Showing results 1 to 28 of 28

Collection:

Collection ID:CO000834
Collection Summary:none
Sample Type:Blood

Treatment:

Treatment ID:TR000854
Treatment Summary:-none

Sample Preparation:

Sampleprep ID:SP000847
Sampleprep Summary:-
Sampleprep Protocol Filename:A003_-_Untargeted_Metabolomics.pdf

Combined analysis:

Analysis ID AN001288 AN001289
Analysis type MS MS
Chromatography type Reversed phase Reversed phase
Chromatography system Agilent Agilent
Column Waters Acquity HSS T3 (50 x 2.1mm, 1.8um) Waters Acquity HSS T3 (50 x 2.1mm, 1.8um)
MS Type ESI ESI
MS instrument type QTOF QTOF
MS instrument name Agilent 6530 QTOF Agilent 6530 QTOF
Ion Mode NEGATIVE POSITIVE
Units peak area peak area

Chromatography:

Chromatography ID:CH000904
Instrument Name:Agilent
Column Name:Waters Acquity HSS T3 (50 x 2.1mm, 1.8um)
Chromatography Type:Reversed phase

MS:

MS ID:MS001181
Analysis ID:AN001288
Instrument Name:Agilent 6530 QTOF
Instrument Type:QTOF
MS Type:ESI
Ion Mode:NEGATIVE
  
MS ID:MS001182
Analysis ID:AN001289
Instrument Name:Agilent 6530 QTOF
Instrument Type:QTOF
MS Type:ESI
Ion Mode:POSITIVE
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