Summary of Study ST001727
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001107. The data can be accessed directly via it's Project DOI: 10.21228/M8MD78 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
Study ID | ST001727 |
Study Title | Metabolomics and metagenomics of metformin (Plasma) |
Study Summary | Metformin affects the gut microbiome and altered microbiota may contribute to the hypoglycemic effect of metformin. Metabolomic analysis can be useful to elucidate the potential underlying mechanisms of the hypoglycemic effect according to the change in the microbiome and metabolites induced by the administration of metformin. |
Institute | Seoul National University |
Department | Department of Clinical Pharmacology and Therapeutics, College of Medicine and Hospital |
Last Name | Lee |
First Name | Yujin |
Address | 101 Daehak-ro, Jongno-gu, Seoul 110-799, Korea |
yoojinlee@snu.ac.kr | |
Phone | +821033804686 |
Submit Date | 2021-03-16 |
Raw Data Available | Yes |
Raw Data File Type(s) | smp |
Analysis Type Detail | GC-MS |
Release Date | 2021-08-31 |
Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Project:
Project ID: | PR001107 |
Project DOI: | doi: 10.21228/M8MD78 |
Project Title: | Metabolomics and metagenomics of metformin (Plasma) |
Project Summary: | Metformin affects the gut microbiome and altered microbiota may contribute to the hypoglycemic effect of metformin. Metabolomic analysis can be useful to elucidate the potential underlying mechanisms of the hypoglycemic effect according to the change in the microbiome and metabolites induced by the administration of metformin. |
Institute: | Seoul National University |
Department: | Department of Clinical Pharmacology and Therapeutics, College of Medicine and Hospital |
Laboratory: | Metabolomics analysis lab |
Last Name: | Lee |
First Name: | Yujin |
Address: | 101 Daehak-ro, Jongno-gu, Seoul 110-799, Korea |
Email: | yoojinlee@snu.ac.kr |
Phone: | +821033804686 |
Subject:
Subject ID: | SU001804 |
Subject Type: | Human |
Subject Species: | Homo sapiens |
Taxonomy ID: | 9606 |
Gender: | Male |
Factors:
Subject type: Human; Subject species: Homo sapiens (Factor headings shown in green)
mb_sample_id | local_sample_id | Gender | Race | Group |
---|---|---|---|---|
SA162501 | R204-P1 | Male | Asian | Control |
SA162502 | R202-P1 | Male | Asian | Control |
SA162503 | R201-P1 | Male | Asian | Control |
SA162504 | R205-P1 | Male | Asian | Control |
SA162505 | R207-P1 | Male | Asian | Control |
SA162506 | R101-P1 | Male | Asian | Control |
SA162507 | R210-P1 | Male | Asian | Control |
SA162508 | R114-P1 | Male | Asian | Control |
SA162509 | R206-P1 | Male | Asian | Control |
SA162510 | R203-P1 | Male | Asian | Control |
SA162511 | R106-P1 | Male | Asian | Control |
SA162512 | R105-P1 | Male | Asian | Control |
SA162513 | R113-P1 | Male | Asian | Control |
SA162514 | R102-P1 | Male | Asian | Control |
SA162515 | R107-P1 | Male | Asian | Control |
SA162516 | R103-P1 | Male | Asian | Control |
SA162517 | R109-P1 | Male | Asian | Control |
SA162518 | R112-P1 | Male | Asian | Control |
SA162519 | R111-P1 | Male | Asian | Control |
SA162520 | R110-P1 | Male | Asian | Control |
SA162521 | R203-P2 | Male | Asian | Treated |
SA162522 | R202-P2 | Male | Asian | Treated |
SA162523 | R201-P2 | Male | Asian | Treated |
SA162524 | R204-P2 | Male | Asian | Treated |
SA162525 | R207-P2 | Male | Asian | Treated |
SA162526 | R114-P2 | Male | Asian | Treated |
SA162527 | R210-P2 | Male | Asian | Treated |
SA162528 | R206-P2 | Male | Asian | Treated |
SA162529 | R205-P2 | Male | Asian | Treated |
SA162530 | R101-P2 | Male | Asian | Treated |
SA162531 | R106-P2 | Male | Asian | Treated |
SA162532 | R105-P2 | Male | Asian | Treated |
SA162533 | R103-P2 | Male | Asian | Treated |
SA162534 | R102-P2 | Male | Asian | Treated |
SA162535 | R107-P2 | Male | Asian | Treated |
SA162536 | R109-P2 | Male | Asian | Treated |
SA162537 | R112-P2 | Male | Asian | Treated |
SA162538 | R111-P2 | Male | Asian | Treated |
SA162539 | R110-P2 | Male | Asian | Treated |
SA162540 | R113-P2 | Male | Asian | Treated |
Showing results 1 to 40 of 40 |
Collection:
Collection ID: | CO001797 |
Collection Summary: | We recruited and included 20 healthy adult male subjects. |
Sample Type: | Blood (plasma) |
Treatment:
Treatment ID: | TR001817 |
Treatment Summary: | The subjects received oral metformin 1000mg twice daily. |
Sample Preparation:
Sampleprep ID: | SP001810 |
Sampleprep Summary: | The samples were extracted twice. |
Combined analysis:
Analysis ID | AN002812 |
---|---|
Analysis type | MS |
Chromatography type | GC |
Chromatography system | Agilent 7890B |
Column | Restek Rtx-5Sil (30m x 0.25mm,0.25um) |
MS Type | EI |
MS instrument type | GC-TOF |
MS instrument name | Leco Pegasus HT TOF |
Ion Mode | NEGATIVE |
Units | intensity |
Chromatography:
Chromatography ID: | CH002077 |
Instrument Name: | Agilent 7890B |
Column Name: | Restek Rtx-5Sil (30m x 0.25mm,0.25um) |
Chromatography Type: | GC |
MS:
MS ID: | MS002606 |
Analysis ID: | AN002812 |
Instrument Name: | Leco Pegasus HT TOF |
Instrument Type: | GC-TOF |
MS Type: | EI |
MS Comments: | Leco chroma TOF-GC Software v4. |
Ion Mode: | NEGATIVE |