ST002856 Validation of on-target effect of IACS-010759 in vehicle- and Enzalutamide-treated 16D cells
Limit by pathway class:
   Minimum # of metabolites per pathway:

Pathway name (# of metabolites detected in this study)HMDB pathwayKEGG pathway
Alanine Metabolism (12) SMP0000055 map00250
Amino Sugar Metabolism (5) SMP0000045 map00520
Ammonia Recycling (18) SMP0000009 map00910
Arginine and Proline Metabolism (21) SMP0000020 map00330
Aspartate Metabolism (25) SMP0000067 map00250
beta-Alanine Metabolism (7) SMP0000007 map00410
Butyrate Metabolism (6) SMP0000073 map00650
Carnitine Synthesis (13) SMP0000465 -
Citric Acid Cycle (24) SMP0000057 map00020
Cysteine Metabolism (17) SMP0000013 map00270
D-Arginine and D-Ornithine Metabolism (2) SMP0000036 map00472
Gluconeogenesis (12) SMP0000128 map00010
Glucose-Alanine Cycle (12) SMP0000127 -
Glutamate Metabolism (29) SMP0000072 map00250
Glutathione Metabolism (5) SMP0000015 map00480
Glycine and Serine Metabolism (17) SMP0000004 map00260
Glycolysis (5) SMP0000040 map00010
Homocysteine Degradation (5) SMP0000455 -
Ketone Body Metabolism (6) SMP0000071 map00072
Lysine Degradation (7) SMP0000037 map00310
Malate-Aspartate Shuttle (7) SMP0000129 -
Methionine Metabolism (5) SMP0000033 map00270
Mitochondrial Electron Transport Chain (12) SMP0000355 map00190
Oxidation of Branched Chain Fatty Acids (13) SMP0000030 -
Oxidation of Branched-Chain Fatty Acids (13) SMP0000030 -
Pantothenate and CoA Biosynthesis (5) SMP0000027 map00770
Phenylalanine and Tyrosine Metabolism (13) SMP0000008 map00360
Phytanic Acid Peroxisomal Oxidation (13) SMP0000450 -
Propanoate Metabolism (7) SMP0000016 map00640
Purine Metabolism (6) SMP0000050 map00230
Pyruvaldehyde Degradation (5) SMP0000459 -
Pyruvate Metabolism (5) SMP0000060 map00620
Taurine and Hypotaurine Metabolism (5) SMP0000021 map00430
Transfer of Acetyl Groups into Mitochondria (5) SMP0000466 -
Tryptophan Metabolism (7) SMP0000063 map00380
Tyrosine Metabolism (13) SMP0000006 map00350
Urea Cycle (20) SMP0000059 map00330
Valine, Leucine and Isoleucine Degradation (22) SMP0000032 map00280
Warburg Effect (24) SMP0000654 -
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