ST004228 Aromatic Microbial Metabolite Hippuric Acid Potentiates Pro-Inflammatory Responses in Macrophages through TLR-MyD88 Signaling and Lipid Remodeling - Non-targeted metabolomics of C57BL/6 mice infected with Escherichia coli
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   Minimum # of metabolites per pathway:

Pathway name (# of metabolites detected in this study)HMDB pathwayKEGG pathway
Alanine Metabolism (1) SMP0000055 map00250
Amino Sugar Metabolism (2) SMP0000045 map00520
Ammonia Recycling (1) SMP0000009 map00910
Arachidonic Acid Metabolism (1) SMP0000075 map00590
Arginine and Proline Metabolism (5) SMP0000020 map00330
Aspartate Metabolism (1) SMP0000067 map00250
beta-Alanine Metabolism (2) SMP0000007 map00410
Betaine Metabolism (4) SMP0000123 map00260
Butyrate Metabolism (1) SMP0000073 map00650
Cardiolipin Biosynthesis (1) SMP0020986 -
Carnitine Synthesis (2) SMP0000465 -
Catecholamine Biosynthesis (1) SMP0000012 map00350
Citric Acid Cycle (5) SMP0000057 map00020
Cysteine Metabolism (1) SMP0000013 map00270
De Novo Triacylglycerol Biosynthesis (1) SMP0015896 -
Estrone Metabolism (1) SMP0030880 -
Fatty Acid Biosynthesis (1) SMP0000456 -
Galactose Metabolism (2) SMP0000043 map00052
Gluconeogenesis (6) SMP0000128 map00010
Glucose-Alanine Cycle (1) SMP0000127 -
Glutamate Metabolism (3) SMP0000072 map00250
Glutathione Metabolism (1) SMP0000015 map00480
Glycerolipid Metabolism (2) SMP0000039 map00561
Glycerol Phosphate Shuttle (1) SMP0000124 -
Glycine and Serine Metabolism (6) SMP0000004 map00260
Glycolysis (5) SMP0000040 map00010
Histidine Metabolism (2) SMP0000044 map00340
Inositol Metabolism (1) SMP0000011 map00562
Inositol Phosphate Metabolism (1) SMP0000462 map00562
Ketone Body Metabolism (1) SMP0000071 map00072
Lactose Synthesis (1) SMP0000444 -
Malate-Aspartate Shuttle (1) SMP0000129 -
Methionine Metabolism (5) SMP0000033 map00270
Methylhistidine Metabolism (1) SMP0000715 -
Mitochondrial Electron Transport Chain (2) SMP0000355 map00190
Nicotinate and Nicotinamide Metabolism (1) SMP0000048 map00760
Nucleotide Sugars Metabolism (2) SMP0000010 map00520
Oxidation of Branched Chain Fatty Acids (1) SMP0000030 -
Oxidation of Branched-Chain Fatty Acids (1) SMP0000030 -
Pentose Phosphate Pathway (1) SMP0000031 map00030
Phosphatidylcholine Biosynthesis (2) SMP0014212 -
Phosphatidylethanolamine Biosynthesis (1) SMP0029731 -
Phospholipid Biosynthesis (2) SMP0000025 map00564
Phytanic Acid Peroxisomal Oxidation (1) SMP0000450 -
Purine Metabolism (5) SMP0000050 map00230
Pyrimidine Metabolism (5) SMP0000046 map00240
Pyruvaldehyde Degradation (1) SMP0000459 -
Pyruvate Metabolism (3) SMP0000060 map00620
Selenoamino Acid Metabolism (1) SMP0000029 map00450
Spermidine and Spermine Biosynthesis (2) SMP0000445 -
Starch and Sucrose Metabolism (3) SMP0000058 map00500
Transfer of Acetyl Groups into Mitochondria (3) SMP0000466 -
Tryptophan Metabolism (1) SMP0000063 map00380
Tyrosine Metabolism (1) SMP0000006 map00350
Ubiquinone Biosynthesis (1) SMP0000065 map00130
Urea Cycle (3) SMP0000059 map00330
Valine, Leucine and Isoleucine Degradation (1) SMP0000032 map00280
Warburg Effect (6) SMP0000654 -
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