List of human metabolic pathways and metabolites (REACTOME)

Pathway name (# of metabolites detected in study)Reactome pathway
Acetylcholine regulates insulin secretion REACT_18405
Activation of Rac REACT_19226
Activation of RAS in B cells REACT_118778
Activation of the phototransduction cascade REACT_163932
Adenylate cyclase activating pathway REACT_15312
Adenylate cyclase inhibitory pathway REACT_15333
ADP signalling through P2Y purinoceptor 1 REACT_19140
ADP signalling through P2Y purinoceptor 12 REACT_20653
Adrenaline,noradrenaline inhibits insulin secretion REACT_18339
Amino acid synthesis and interconversion (transamination) REACT_238
Antigen Presentation: Folding, assembly and peptide loading of class I MHC REACT_75795
ARMS-mediated activation REACT_12002
Axonal growth inhibition (RHOA activation) REACT_13815
Ca2+ pathway REACT_172761
CD28 dependent Vav1 pathway REACT_19238
CDO in myogenesis REACT_21402
Citric acid cycle (TCA cycle) REACT_1785
Clathrin derived vesicle budding REACT_19187
COPII (Coat Protein 2) Mediated Vesicle Transport REACT_12507
COPI Mediated Transport REACT_11096
CREB phosphorylation through the activation of Ras REACT_20568
DAP12 signaling REACT_147814
DCC mediated attractive signaling REACT_22351
Downstream signal transduction REACT_17025
DSCAM interactions REACT_25299
EGFR downregulation REACT_12484
EGFR Transactivation by Gastrin REACT_121096
EPHA-mediated growth cone collapse REACT_228063
EPHB-mediated forward signaling REACT_228085
EPH-ephrin mediated repulsion of cells REACT_228189
Ephrin signaling REACT_228226
Eukaryotic Translation Elongation REACT_1477
Eukaryotic Translation Termination REACT_1986
Factors involved in megakaryocyte development and platelet production REACT_24970
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion REACT_19193
FCERI mediated MAPK activation REACT_163701
Formation of the ternary complex, and subsequently, the 43S complex REACT_1079
Formation of tubulin folding intermediates by CCT/TriC REACT_16956
Frs2-mediated activation REACT_12076
FRS2-mediated cascade REACT_21247
G alpha (12/13) signalling events REACT_18407
G alpha (i) signalling events REACT_19231
G alpha (q) signalling events REACT_18283
G alpha (s) signalling events REACT_19327
G alpha (z) signalling events REACT_19333
Gap junction assembly REACT_9509
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion REACT_18274
Glucagon signaling in metabolic regulation REACT_1665
Gluconeogenesis REACT_1520
Golgi Associated Vesicle Biogenesis REACT_19400
Golgi Cisternae Pericentriolar Stack Reorganization REACT_1100
G-protein activation REACT_15457
GPVI-mediated activation cascade REACT_1695
GRB2 events in EGFR signaling REACT_12606
GRB2 events in ERBB2 signaling REACT_115854
GRB2:SOS provides linkage to MAPK signaling for Integrins REACT_15443
GTP hydrolysis and joining of the 60S ribosomal subunit REACT_2085
Hedgehog 'off' state REACT_267634
Inactivation of Cdc42 and Rac REACT_19342
Inactivation, recovery and regulation of the phototransduction cascade REACT_163919
Integrin alphaIIb beta3 signaling REACT_15523
Interleukin receptor SHC signaling REACT_23891
Kinesins REACT_25201
L13a-mediated translational silencing of Ceruloplasmin expression REACT_79
Lysosome Vesicle Biogenesis REACT_19287
MEK activation REACT_962
MHC class II antigen presentation REACT_121399
MicroRNA (miRNA) biogenesis REACT_12417
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane REACT_11039
Mitochondrial translation elongation REACT_267677
Mitochondrial translation initiation REACT_267680
Mitochondrial translation termination REACT_267602
Mitotic Prometaphase REACT_682
Molybdenum cofactor biosynthesis REACT_25073
mRNA Capping REACT_1470
mTOR signalling REACT_6838
NCAM signaling for neurite out-growth REACT_18334
NEP/NS2 Interacts with the Cellular Export Machinery REACT_6179
Nitric oxide stimulates guanylate cyclase REACT_23862
NRAGE signals death through JNK REACT_13638
Nuclear import of Rev protein REACT_9395
Orphan transporters REACT_267716
p130Cas linkage to MAPK signaling for integrins REACT_15381
p38MAPK events REACT_12065
PCP/CE pathway REACT_172581
Peptide chain elongation REACT_1404
PKA activation in glucagon signalling REACT_1946
Platelet degranulation REACT_318
PLC beta mediated events REACT_15426
Post-chaperonin tubulin folding pathway REACT_16967
Prostacyclin signalling through prostacyclin receptor REACT_23946
Purine ribonucleoside monophosphate biosynthesis REACT_1776
RAF activation REACT_2077
RAF phosphorylates MEK REACT_614
Rap1 signalling REACT_23898
Ras activation uopn Ca2+ infux through NMDA receptor REACT_20546
Recruitment of NuMA to mitotic centrosomes REACT_15510
Recycling of eIF2:GDP REACT_1815
Recycling pathway of L1 REACT_22365
Regulation of actin dynamics for phagocytic cup formation REACT_160086
Regulation of cholesterol biosynthesis by SREBP (SREBF) REACT_147797
Regulation of insulin secretion REACT_18325
Regulation of PLK1 Activity at G2/M Transition REACT_160315
Regulation of Rheb GTPase activity by AMPK REACT_21393
Release of eIF4E REACT_6836
Resolution of Sister Chromatid Cohesion REACT_150425
Retrograde neurotrophin signalling REACT_12435
Rev-mediated nuclear export of HIV RNA REACT_6190
Rho GTPase cycle REACT_11051
Ribosomal scanning and start codon recognition REACT_931
S6K1-mediated signalling REACT_6754
Sema3A PAK dependent Axon repulsion REACT_19236
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion REACT_19279
Sema4D induced cell migration and growth-cone collapse REACT_19277
Sema4D mediated inhibition of cell attachment and migration REACT_19266
Separation of Sister Chromatids REACT_150471
SHC1 events in EGFR signaling REACT_12579
SHC1 events in ERBB2 signaling REACT_115993
SHC1 events in ERBB4 signaling REACT_116005
SHC-mediated cascade REACT_21374
SHC-mediated signalling REACT_661
Signaling by constitutively active EGFR REACT_115852
Signaling by FGFR mutants REACT_121398
Signaling by SCF-KIT REACT_111040
Signalling to p38 via RIT and RIN REACT_12077
Signalling to RAS REACT_12033
Signal transduction by L1 REACT_22272
SOS-mediated signalling REACT_524
STING mediated induction of host immune responses REACT_147841
Synthesis and interconversion of nucleotide di- and triphosphates REACT_21330
Synthesis of GDP-mannose REACT_22423
Synthesis of PIPs at the Golgi membrane REACT_120836
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation REACT_111176
The proton buffering model REACT_6196
Thrombin signalling through proteinase activated receptors (PARs) REACT_21384
Thromboxane signalling through TP receptor REACT_20647
Tie2 Signaling REACT_12621
Transcriptional regulation by small RNAs REACT_267668
Translation initiation complex formation REACT_1979
Translocation of GLUT4 to the plasma membrane REACT_147867
Vasopressin regulates renal water homeostasis via Aquaporins REACT_24023
VEGFA-VEGFR2 Pathway REACT_228166
VEGFR2 mediated cell proliferation REACT_228024
VEGFR2 mediated vascular permeability REACT_228016
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