ST000045 Plasma metabolomics: Comparison of non-diabetic controls with T1D patients
List of human metabolic pathways and metabolites (REACTOME)

Pathway name (# of metabolites detected in study)Reactome pathway
Abnormal metabolism in phenylketonuria (1) REACT_121117
Acyl chain remodeling of DAG and TAG (1) REACT_121122
Amino acid synthesis and interconversion (transamination) (1) REACT_238
Amino acid transport across the plasma membrane (3) REACT_13796
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (3) REACT_75795
Antigen processing: Ubiquitination & Proteasome degradation (3) REACT_75842
Arachidonate production from DAG (1) REACT_19308
Branched-chain amino acid catabolism (1) REACT_197
Class A/1 (Rhodopsin-like receptors) (1) REACT_14828
Class II GLUTs (1) REACT_19281
Cross-presentation of soluble exogenous antigens (endosomes) (3) REACT_111056
CYP2E1 reactions (2) REACT_13797
Cytosolic sulfonation of small molecules (2) REACT_6913
Cytosolic tRNA aminoacylation (3) REACT_15306
Digestion of dietary lipid (1) REACT_9518
Endosomal/Vacuolar pathway (3) REACT_111168
ER-Phagosome pathway (3) REACT_111178
G alpha (i) signalling events (1) REACT_19231
Glucuronidation (1) REACT_6784
Glutathione synthesis and recycling (4) REACT_6960
Glyoxylate metabolism (1) REACT_16925
Histidine catabolism (1) REACT_1249
Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis (1) REACT_494
Hydroxycarboxylic acid-binding receptors (1) REACT_163785
Mitochondrial iron-sulfur cluster biogenesis (1) REACT_150353
Mitochondrial tRNA aminoacylation (3) REACT_15302
Molybdenum cofactor biosynthesis (1) REACT_25073
Na+/Cl- dependent neurotransmitter transporters (3) REACT_20506
Nicotinamide salvaging (1) REACT_11213
Organic anion transport (2) REACT_22310
Orphan transporters (1) REACT_267716
Passive transport by Aquaporins (1) REACT_23826
Phenylalanine and tyrosine catabolism (1) REACT_1786
Proton-coupled monocarboxylate transport (1) REACT_20515
Proton-coupled neutral amino acid transporters (1) REACT_19348
Proton/oligonucleotide cotransporters (3) REACT_19328
Purine catabolism (1) REACT_2086
Pyrimidine catabolism (2) REACT_1023
Pyrimidine salvage reactions (1) REACT_655
Recycling of bile acids and salts (1) REACT_11042
Stimuli-sensing channels (1) REACT_160189
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (1) REACT_11041
Synthesis of Ketone Bodies (1) REACT_1464
Synthesis of PG (1) REACT_121280
Thyroxine biosynthesis (1) REACT_15292
Transport of glycerol from adipocytes to the liver by Aquaporins (1) REACT_23809
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (1) REACT_1206
Transport of organic anions (2) REACT_23988
Triglyceride Biosynthesis (1) REACT_1190
Tryptophan catabolism (1) REACT_916
Utilization of Ketone Bodies (1) REACT_59
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