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ST000148 A549 13C-labeled Cell StudyList of human metabolic pathways and metabolites (REACTOME)
Pathway name (# of metabolites detected in study)
Reactome pathway
ABC-family proteins mediated transport (1)
REACT_15480
ABH2 mediated Reversal of Alkylation Damage (2)
REACT_526
ABH3 mediated Reversal of Alkylation Damage (2)
REACT_1662
Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate (1)
REACT_160183
Abnormal metabolism in phenylketonuria (4)
REACT_121117
Activation of gene expression by SREBF (SREBP) (1)
REACT_147904
Alpha-oxidation of phytanate (2)
REACT_17003
Amino acid synthesis and interconversion (transamination) (3)
REACT_238
Androgen biosynthesis (2)
REACT_11059
Beta oxidation of myristoyl-CoA to lauroyl-CoA (1)
REACT_2108
Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB (3)
REACT_416
Biosynthesis of A2E, implicated in retinal degradation (1)
REACT_160194
BMAL1:CLOCK,NPAS2 activates circadian gene expression (1)
REACT_111118
Branched-chain amino acid catabolism (1)
REACT_197
Carnitine synthesis (2)
REACT_2125
Catecholamine biosynthesis (1)
REACT_15551
Circadian Clock (1)
REACT_24941
Citric acid cycle (TCA cycle) (2)
REACT_1785
Class A/1 (Rhodopsin-like receptors) (1)
REACT_14828
Class C/3 (Metabotropic glutamate/pheromone receptors) (1)
REACT_18319
Collagen biosynthesis and modifying enzymes (2)
REACT_121139
Condensation of Prophase Chromosomes (1)
REACT_172744
Constitutive PI3K/AKT Signaling in Cancer (1)
REACT_147727
CYP2E1 reactions (1)
REACT_13797
Degradation of GABA (1)
REACT_23964
Digestion of dietary lipid (1)
REACT_9518
Endogenous sterols (4)
REACT_13812
eNOS activation (1)
REACT_12477
Estrogen biosynthesis (1)
REACT_11037
Ethanol oxidation (1)
REACT_34
Fatty acids (1)
REACT_13814
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (4)
REACT_19193
Fatty Acyl-CoA Biosynthesis (2)
REACT_1319
Free fatty acid receptors (6)
REACT_21268
Fructose catabolism (2)
REACT_1571
G alpha (i) signalling events (2)
REACT_19231
G alpha (q) signalling events (4)
REACT_18283
Glucocorticoid biosynthesis (1)
REACT_11036
Gluconeogenesis (4)
REACT_1520
Glutathione synthesis and recycling (1)
REACT_6960
Glycolysis (2)
REACT_1383
Glycosphingolipid metabolism (1)
REACT_116105
Glyoxylate metabolism (2)
REACT_16925
HDMs demethylate histones (1)
REACT_228178
Inactivation, recovery and regulation of the phototransduction cascade (1)
REACT_163919
Insulin effects increased synthesis of Xylulose-5-Phosphate (1)
REACT_939
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate (1)
REACT_25367
Interconversion of polyamines (1)
REACT_14805
Lysine catabolism (2)
REACT_1298
Metabolism of serotonin (1)
REACT_15532
Mineralocorticoid biosynthesis (2)
REACT_11047
NADPH regeneration (1)
REACT_16904
Organic anion transport (1)
REACT_22310
Organic anion transporters (1)
REACT_19372
Orphan transporters (1)
REACT_267716
Oxidative Stress Induced Senescence (1)
REACT_169436
Oxygen-dependent asparagine hydroxylation of Hypoxia-inducible Factor Alpha (1)
REACT_121226
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (1)
REACT_120916
PAOs oxidise polyamines to amines (1)
REACT_505
Pentose phosphate pathway (hexose monophosphate shunt) (1)
REACT_1859
Phenylalanine and tyrosine catabolism (2)
REACT_1786
Plasmalogen biosynthesis (1)
REACT_1407
PPARA activates gene expression (1)
REACT_116145
Pregnenolone biosynthesis (1)
REACT_11038
Proton-coupled monocarboxylate transport (2)
REACT_20515
Pyrimidine catabolism (1)
REACT_1023
Pyruvate metabolism (1)
REACT_2071
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) (1)
REACT_19241
Regulation of pyruvate dehydrogenase (PDH) complex (1)
REACT_12528
Retinoid cycle disease events (2)
REACT_160130
Retinoid metabolism and transport (3)
REACT_24968
REV-ERBA represses gene expression (1)
REACT_118789
RORA activates circadian gene expression (1)
REACT_118659
Serine biosynthesis (2)
REACT_115789
Sialic acid metabolism (1)
REACT_200874
Signaling by constitutively active EGFR (1)
REACT_115852
Sphingolipid de novo biosynthesis (3)
REACT_115810
Sterols are 12-hydroxylated by CYP8B1 (1)
REACT_13438
Synthesis of 15-eicosatetraenoic acid derivatives (1)
REACT_150422
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (3)
REACT_11041
Synthesis of Ketone Bodies (1)
REACT_1464
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (3)
REACT_150149
Synthesis of very long-chain fatty acyl-CoAs (1)
REACT_380
Synthesis, secretion, and deacylation of Ghrelin (1)
REACT_19189
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) (6)
REACT_24019
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) (4)
REACT_23824
TET1,2,3 and TDG demethylate DNA (2)
REACT_200682
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (1)
REACT_111176
The canonical retinoid cycle in rods (twilight vision) (3)
REACT_160156
The retinoid cycle in cones (daylight vision) (2)
REACT_160083
Transcriptional activation of mitochondrial biogenesis (1)
REACT_200608
Transcriptional regulation of white adipocyte differentiation (1)
REACT_27161
Transport of fatty acids (6)
REACT_23892
Tryptophan catabolism (6)
REACT_916
Utilization of Ketone Bodies (1)
REACT_59
VEGFR2 mediated cell proliferation (1)
REACT_228024
Vitamin C (ascorbate) metabolism (1)
REACT_11202
Vitamins B6 activation to pyridoxal phosphate (1)
REACT_25012
YAP1- and WWTR1 (TAZ)-stimulated gene expression (1)
REACT_118713
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