ST000148 A549 13C-labeled Cell Study
List of human metabolic pathways and metabolites (REACTOME)

Pathway name (# of metabolites detected in study)Reactome pathway
ABC-family proteins mediated transport (1) REACT_15480
ABH2 mediated Reversal of Alkylation Damage (2) REACT_526
ABH3 mediated Reversal of Alkylation Damage (2) REACT_1662
Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate (1) REACT_160183
Abnormal metabolism in phenylketonuria (4) REACT_121117
Activation of gene expression by SREBF (SREBP) (1) REACT_147904
Alpha-oxidation of phytanate (2) REACT_17003
Amino acid synthesis and interconversion (transamination) (3) REACT_238
Androgen biosynthesis (2) REACT_11059
Beta oxidation of myristoyl-CoA to lauroyl-CoA (1) REACT_2108
Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB (3) REACT_416
Biosynthesis of A2E, implicated in retinal degradation (1) REACT_160194
BMAL1:CLOCK,NPAS2 activates circadian gene expression (1) REACT_111118
Branched-chain amino acid catabolism (1) REACT_197
Carnitine synthesis (2) REACT_2125
Catecholamine biosynthesis (1) REACT_15551
Circadian Clock (1) REACT_24941
Citric acid cycle (TCA cycle) (2) REACT_1785
Class A/1 (Rhodopsin-like receptors) (1) REACT_14828
Class C/3 (Metabotropic glutamate/pheromone receptors) (1) REACT_18319
Collagen biosynthesis and modifying enzymes (2) REACT_121139
Condensation of Prophase Chromosomes (1) REACT_172744
Constitutive PI3K/AKT Signaling in Cancer (1) REACT_147727
CYP2E1 reactions (1) REACT_13797
Degradation of GABA (1) REACT_23964
Digestion of dietary lipid (1) REACT_9518
Endogenous sterols (4) REACT_13812
eNOS activation (1) REACT_12477
Estrogen biosynthesis (1) REACT_11037
Ethanol oxidation (1) REACT_34
Fatty acids (1) REACT_13814
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (4) REACT_19193
Fatty Acyl-CoA Biosynthesis (2) REACT_1319
Free fatty acid receptors (6) REACT_21268
Fructose catabolism (2) REACT_1571
G alpha (i) signalling events (2) REACT_19231
G alpha (q) signalling events (4) REACT_18283
Glucocorticoid biosynthesis (1) REACT_11036
Gluconeogenesis (4) REACT_1520
Glutathione synthesis and recycling (1) REACT_6960
Glycolysis (2) REACT_1383
Glycosphingolipid metabolism (1) REACT_116105
Glyoxylate metabolism (2) REACT_16925
HDMs demethylate histones (1) REACT_228178
Inactivation, recovery and regulation of the phototransduction cascade (1) REACT_163919
Insulin effects increased synthesis of Xylulose-5-Phosphate (1) REACT_939
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate (1) REACT_25367
Interconversion of polyamines (1) REACT_14805
Lysine catabolism (2) REACT_1298
Metabolism of serotonin (1) REACT_15532
Mineralocorticoid biosynthesis (2) REACT_11047
NADPH regeneration (1) REACT_16904
Organic anion transport (1) REACT_22310
Organic anion transporters (1) REACT_19372
Orphan transporters (1) REACT_267716
Oxidative Stress Induced Senescence (1) REACT_169436
Oxygen-dependent asparagine hydroxylation of Hypoxia-inducible Factor Alpha (1) REACT_121226
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (1) REACT_120916
PAOs oxidise polyamines to amines (1) REACT_505
Pentose phosphate pathway (hexose monophosphate shunt) (1) REACT_1859
Phenylalanine and tyrosine catabolism (2) REACT_1786
Plasmalogen biosynthesis (1) REACT_1407
PPARA activates gene expression (1) REACT_116145
Pregnenolone biosynthesis (1) REACT_11038
Proton-coupled monocarboxylate transport (2) REACT_20515
Pyrimidine catabolism (1) REACT_1023
Pyruvate metabolism (1) REACT_2071
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) (1) REACT_19241
Regulation of pyruvate dehydrogenase (PDH) complex (1) REACT_12528
Retinoid cycle disease events (2) REACT_160130
Retinoid metabolism and transport (3) REACT_24968
REV-ERBA represses gene expression (1) REACT_118789
RORA activates circadian gene expression (1) REACT_118659
Serine biosynthesis (2) REACT_115789
Sialic acid metabolism (1) REACT_200874
Signaling by constitutively active EGFR (1) REACT_115852
Sphingolipid de novo biosynthesis (3) REACT_115810
Sterols are 12-hydroxylated by CYP8B1 (1) REACT_13438
Synthesis of 15-eicosatetraenoic acid derivatives (1) REACT_150422
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (3) REACT_11041
Synthesis of Ketone Bodies (1) REACT_1464
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (3) REACT_150149
Synthesis of very long-chain fatty acyl-CoAs (1) REACT_380
Synthesis, secretion, and deacylation of Ghrelin (1) REACT_19189
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) (6) REACT_24019
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) (4) REACT_23824
TET1,2,3 and TDG demethylate DNA (2) REACT_200682
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (1) REACT_111176
The canonical retinoid cycle in rods (twilight vision) (3) REACT_160156
The retinoid cycle in cones (daylight vision) (2) REACT_160083
Transcriptional activation of mitochondrial biogenesis (1) REACT_200608
Transcriptional regulation of white adipocyte differentiation (1) REACT_27161
Transport of fatty acids (6) REACT_23892
Tryptophan catabolism (6) REACT_916
Utilization of Ketone Bodies (1) REACT_59
VEGFR2 mediated cell proliferation (1) REACT_228024
Vitamin C (ascorbate) metabolism (1) REACT_11202
Vitamins B6 activation to pyridoxal phosphate (1) REACT_25012
YAP1- and WWTR1 (TAZ)-stimulated gene expression (1) REACT_118713
  logo