ST000153 Primary T Cell Noxa Knockdown (Donor 8)-II
List of human metabolic pathways and metabolites (REACTOME)

Pathway name (# of metabolites detected in study)Reactome pathway
ABH2 mediated Reversal of Alkylation Damage (1) REACT_526
ABH3 mediated Reversal of Alkylation Damage (1) REACT_1662
Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate (1) REACT_160183
Abnormal metabolism in phenylketonuria (4) REACT_121117
Activation of AMPA receptors (1) REACT_18338
Activation of Ca-permeable Kainate Receptor (1) REACT_21346
Activation of Na-permeable Kainate Receptors (1) REACT_21343
Aflatoxin activation and detoxification (1) REACT_228214
Alpha-oxidation of phytanate (1) REACT_17003
Amino acid synthesis and interconversion (transamination) (7) REACT_238
Amino acid transport across the plasma membrane (3) REACT_13796
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (4) REACT_75795
Antigen processing: Ubiquitination & Proteasome degradation (4) REACT_75842
Astrocytic Glutamate-Glutamine Uptake And Metabolism (2) REACT_13639
Branched-chain amino acid catabolism (2) REACT_197
Carnitine synthesis (1) REACT_2125
Citric acid cycle (TCA cycle) (3) REACT_1785
Class A/1 (Rhodopsin-like receptors) (1) REACT_14828
Class C/3 (Metabotropic glutamate/pheromone receptors) (1) REACT_18319
Collagen biosynthesis and modifying enzymes (1) REACT_121139
Condensation of Prophase Chromosomes (1) REACT_172744
Conjugation of phenylacetate with glutamine (1) REACT_6800
CREB phosphorylation through the activation of CaMKII (1) REACT_20642
Cross-presentation of soluble exogenous antigens (endosomes) (4) REACT_111056
Cytosolic tRNA aminoacylation (4) REACT_15306
Degradation of GABA (2) REACT_23964
Endosomal/Vacuolar pathway (4) REACT_111168
EPHB-mediated forward signaling (1) REACT_228085
ER-Phagosome pathway (4) REACT_111178
Fatty Acyl-CoA Biosynthesis (1) REACT_1319
GABA synthesis (1) REACT_24020
G alpha (i) signalling events (3) REACT_19231
G alpha (q) signalling events (1) REACT_18283
Gluconeogenesis (5) REACT_1520
Glutamate Neurotransmitter Release Cycle (2) REACT_12591
Glutathione synthesis and recycling (4) REACT_6960
Glycolysis (1) REACT_1383
Glyoxylate metabolism (2) REACT_16925
HDMs demethylate histones (1) REACT_228178
Histidine catabolism (1) REACT_1249
HS-GAG degradation (1) REACT_120752
Hydroxycarboxylic acid-binding receptors (1) REACT_163785
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate (1) REACT_25367
Lysine catabolism (2) REACT_1298
Metabolism of folate and pterines (1) REACT_11167
Mitochondrial iron-sulfur cluster biogenesis (1) REACT_150353
Mitochondrial tRNA aminoacylation (4) REACT_15302
Molybdenum cofactor biosynthesis (1) REACT_25073
Na+/Cl- dependent neurotransmitter transporters (2) REACT_20506
NADPH regeneration (1) REACT_16904
Nicotinate metabolism (2) REACT_11088
Organic anion transport (2) REACT_22310
Organic anion transporters (3) REACT_19372
Oxidative Stress Induced Senescence (1) REACT_169436
Oxygen-dependent asparagine hydroxylation of Hypoxia-inducible Factor Alpha (1) REACT_121226
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (1) REACT_120916
Phenylalanine and tyrosine catabolism (4) REACT_1786
Presynaptic function of Kainate receptors (1) REACT_21254
Proline catabolism (1) REACT_1002
Proton-coupled monocarboxylate transport (2) REACT_20515
Proton-coupled neutral amino acid transporters (1) REACT_19348
Proton/oligonucleotide cotransporters (4) REACT_19328
Purine ribonucleoside monophosphate biosynthesis (3) REACT_1776
Pyrimidine biosynthesis (3) REACT_21376
Pyrimidine catabolism (2) REACT_1023
Pyruvate metabolism (2) REACT_2071
Ras activation uopn Ca2+ infux through NMDA receptor (1) REACT_20546
Regulation of pyruvate dehydrogenase (PDH) complex (1) REACT_12528
Serine biosynthesis (2) REACT_115789
Sialic acid metabolism (1) REACT_200874
Sulfur amino acid metabolism (1) REACT_115639
Synthesis and interconversion of nucleotide di- and triphosphates (2) REACT_21330
Synthesis of Leukotrienes (LT) and Eoxins (EX) (1) REACT_150420
Synthesis of UDP-N-acetyl-glucosamine (2) REACT_22394
TET1,2,3 and TDG demethylate DNA (1) REACT_200682
Thyroxine biosynthesis (1) REACT_15292
Transport of inorganic cations/anions and amino acids/oligopeptides (2) REACT_19397
Tryptophan catabolism (4) REACT_916
Unblocking of NMDA receptor, glutamate binding and activation (1) REACT_20594
Urea cycle (2) REACT_847
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