ST000980 Metabolomic Analysis of plasma samples from Non-Allergic Subjects and Profilin-Allergic Patients overexposed to Grass Pollen
List of human metabolic pathways and metabolites (REACTOME)

Pathway name (# of metabolites detected in study)Reactome pathway
Abacavir metabolism (1) REACT_121388
Abnormal metabolism in phenylketonuria (2) REACT_121117
Activation of gene expression by SREBF (SREBP) (1) REACT_147904
Adenosine P1 receptors (1) REACT_18288
Agmatine biosynthesis (1) REACT_14800
Amino acid synthesis and interconversion (transamination) (1) REACT_238
Amino acid transport across the plasma membrane (6) REACT_13796
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (6) REACT_75795
Antigen processing: Ubiquitination & Proteasome degradation (6) REACT_75842
BMAL1:CLOCK,NPAS2 activates circadian gene expression (1) REACT_111118
Branched-chain amino acid catabolism (2) REACT_197
Circadian Clock (1) REACT_24941
Cleavage of the damaged purine (1) REACT_1729
Cobalamin (Cbl, vitamin B12) transport and metabolism (1) REACT_163862
Coenzyme A biosynthesis (1) REACT_11218
Cross-presentation of soluble exogenous antigens (endosomes) (6) REACT_111056
Cysteine formation from homocysteine (2) REACT_115589
Cytosolic tRNA aminoacylation (6) REACT_15306
Degradation of cysteine and homocysteine (2) REACT_115654
Digestion of dietary lipid (1) REACT_9518
Endosomal/Vacuolar pathway (6) REACT_111168
eNOS activation (1) REACT_12477
ER-Phagosome pathway (6) REACT_111178
Fatty acids (1) REACT_13814
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (2) REACT_19193
Fatty Acyl-CoA Biosynthesis (1) REACT_1319
Free fatty acid receptors (3) REACT_21268
G alpha (i) signalling events (2) REACT_19231
G alpha (q) signalling events (2) REACT_18283
G alpha (s) signalling events (1) REACT_19327
Gluconeogenesis (1) REACT_1520
Glutathione synthesis and recycling (6) REACT_6960
Glycolysis (1) REACT_1383
Glyoxylate metabolism (2) REACT_16925
Hydroxycarboxylic acid-binding receptors (1) REACT_163785
Inactivation, recovery and regulation of the phototransduction cascade (1) REACT_163919
Inositol transporters (1) REACT_19188
Metabolism of folate and pterines (1) REACT_11167
Methionine salvage pathway (1) REACT_75881
Methylation (2) REACT_6946
Mitochondrial iron-sulfur cluster biogenesis (1) REACT_150353
Mitochondrial tRNA aminoacylation (6) REACT_15302
Molybdenum cofactor biosynthesis (2) REACT_25073
Na+/Cl- dependent neurotransmitter transporters (6) REACT_20506
NGF-independant TRKA activation (1) REACT_11046
Organic anion transport (1) REACT_22310
Organic anion transporters (2) REACT_19372
Orphan transporters (1) REACT_267716
Passive transport by Aquaporins (1) REACT_23826
Phenylalanine and tyrosine catabolism (2) REACT_1786
Plasmalogen biosynthesis (1) REACT_1407
PPARA activates gene expression (1) REACT_116145
Proton-coupled monocarboxylate transport (2) REACT_20515
Proton/oligonucleotide cotransporters (6) REACT_19328
Purine catabolism (2) REACT_2086
Purine salvage (2) REACT_1923
Pyrimidine catabolism (1) REACT_1023
Pyruvate metabolism (2) REACT_2071
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) (1) REACT_19241
Regulation of pyruvate dehydrogenase (PDH) complex (1) REACT_12528
Retinoid cycle disease events (1) REACT_160130
Retinoid metabolism and transport (1) REACT_24968
REV-ERBA represses gene expression (1) REACT_118789
RORA activates circadian gene expression (1) REACT_118659
Serine biosynthesis (1) REACT_115789
Sialic acid metabolism (1) REACT_200874
Sphingolipid de novo biosynthesis (1) REACT_115810
Sulfur amino acid metabolism (3) REACT_115639
Synthesis of IP2, IP, and Ins in the cytosol (1) REACT_150352
Synthesis of PI (1) REACT_121000
Synthesis of PS (1) REACT_120823
Synthesis of very long-chain fatty acyl-CoAs (1) REACT_380
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) (3) REACT_24019
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) (2) REACT_23824
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (1) REACT_111176
The canonical retinoid cycle in rods (twilight vision) (1) REACT_160156
The retinoid cycle in cones (daylight vision) (1) REACT_160083
Transcriptional activation of mitochondrial biogenesis (1) REACT_200608
Transcriptional regulation of white adipocyte differentiation (1) REACT_27161
Transport of fatty acids (3) REACT_23892
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds (1) REACT_19305
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (2) REACT_1206
Tryptophan catabolism (2) REACT_916
Urea cycle (1) REACT_847
YAP1- and WWTR1 (TAZ)-stimulated gene expression (1) REACT_118713
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