ST001285 POAG and Control Aqueous Humor IROA Metabolites from Veterans Affairs Patients NMR (part-II)
List of human metabolic pathways and metabolites (REACTOME)

Pathway name (# of metabolites detected in study)Reactome pathway
ABH2 mediated Reversal of Alkylation Damage (1) REACT_526
ABH3 mediated Reversal of Alkylation Damage (1) REACT_1662
Abnormal metabolism in phenylketonuria (4) REACT_121117
Acetylcholine Neurotransmitter Release Cycle (1) REACT_15309
Acyl chain remodeling of DAG and TAG (2) REACT_121122
Aflatoxin activation and detoxification (1) REACT_228214
Agmatine biosynthesis (1) REACT_14800
Alpha-oxidation of phytanate (1) REACT_17003
Amino acid synthesis and interconversion (transamination) (3) REACT_238
Amino acid transport across the plasma membrane (12) REACT_13796
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (11) REACT_75795
Antigen processing: Ubiquitination & Proteasome degradation (11) REACT_75842
Arachidonate production from DAG (2) REACT_19308
Astrocytic Glutamate-Glutamine Uptake And Metabolism (1) REACT_13639
Beta-oxidation of pristanoyl-CoA (1) REACT_17017
Beta-oxidation of very long chain fatty acids (1) REACT_17062
Biotin transport and metabolism (1) REACT_11153
Branched-chain amino acid catabolism (3) REACT_197
Carnitine synthesis (1) REACT_2125
Catecholamine biosynthesis (2) REACT_15551
Citric acid cycle (TCA cycle) (2) REACT_1785
Class A/1 (Rhodopsin-like receptors) (2) REACT_14828
Class C/3 (Metabotropic glutamate/pheromone receptors) (2) REACT_18319
Collagen biosynthesis and modifying enzymes (2) REACT_121139
Condensation of Prophase Chromosomes (1) REACT_172744
Conjugation of phenylacetate with glutamine (1) REACT_6800
Creatine metabolism (3) REACT_813
Cross-presentation of soluble exogenous antigens (endosomes) (11) REACT_111056
Cytosolic tRNA aminoacylation (11) REACT_15306
Degradation of GABA (1) REACT_23964
Digestion of dietary lipid (1) REACT_9518
Endosomal/Vacuolar pathway (11) REACT_111168
eNOS activation (1) REACT_12477
ER-Phagosome pathway (11) REACT_111178
Ethanol oxidation (1) REACT_34
Fatty Acyl-CoA Biosynthesis (1) REACT_1319
Free fatty acid receptors (1) REACT_21268
G alpha (i) signalling events (3) REACT_19231
G alpha (q) signalling events (3) REACT_18283
Gluconeogenesis (2) REACT_1520
Glutamate Neurotransmitter Release Cycle (1) REACT_12591
Glutathione synthesis and recycling (11) REACT_6960
Glycolysis (2) REACT_1383
Glyoxylate metabolism (2) REACT_16925
HDMs demethylate histones (1) REACT_228178
Histidine catabolism (1) REACT_1249
Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis (1) REACT_494
HS-GAG biosynthesis (1) REACT_121248
Hydrolysis of LPC (1) REACT_120977
Hydroxycarboxylic acid-binding receptors (2) REACT_163785
Inositol transporters (1) REACT_19188
Lysine catabolism (1) REACT_1298
Mitochondrial iron-sulfur cluster biogenesis (1) REACT_150353
Mitochondrial tRNA aminoacylation (11) REACT_15302
Molybdenum cofactor biosynthesis (1) REACT_25073
Na+/Cl- dependent neurotransmitter transporters (12) REACT_20506
Neurotransmitter Clearance In The Synaptic Cleft (1) REACT_13583
Nicotinate metabolism (1) REACT_11088
Nitric oxide stimulates guanylate cyclase (1) REACT_23862
NoRC negatively regulates rRNA expression (1) REACT_200856
Organic anion transport (1) REACT_22310
Organic anion transporters (3) REACT_19372
Organic cation transport (2) REACT_22357
Oxidative Stress Induced Senescence (1) REACT_169436
Oxygen-dependent asparagine hydroxylation of Hypoxia-inducible Factor Alpha (1) REACT_121226
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (1) REACT_120916
Passive transport by Aquaporins (1) REACT_23826
Phagosomal maturation (early endosomal stage) (1) REACT_121256
Phenylalanine and tyrosine catabolism (4) REACT_1786
Proton-coupled monocarboxylate transport (2) REACT_20515
Proton-coupled neutral amino acid transporters (1) REACT_19348
Proton/oligonucleotide cotransporters (11) REACT_19328
Purine ribonucleoside monophosphate biosynthesis (1) REACT_1776
Pyrimidine biosynthesis (1) REACT_21376
Pyrimidine catabolism (2) REACT_1023
Pyruvate metabolism (2) REACT_2071
Regulation of pyruvate dehydrogenase (PDH) complex (1) REACT_12528
Reuptake of GABA (1) REACT_23910
Role of phospholipids in phagocytosis (1) REACT_160158
Serotonin and melatonin biosynthesis (1) REACT_15439
Sialic acid metabolism (1) REACT_200874
Sodium-coupled sulphate, di- and tri-carboxylate transporters (2) REACT_20646
Sulfur amino acid metabolism (1) REACT_115639
Synthesis and interconversion of nucleotide di- and triphosphates (1) REACT_21330
Synthesis of glycosylphosphatidylinositol (GPI) (1) REACT_952
Synthesis of IP2, IP, and Ins in the cytosol (1) REACT_150352
Synthesis of PA (1) REACT_120906
Synthesis of PC (1) REACT_121238
Synthesis of PG (2) REACT_121280
Synthesis of PI (1) REACT_121000
Synthesis of PS (1) REACT_120823
Synthesis of UDP-N-acetyl-glucosamine (1) REACT_22394
Synthesis, secretion, and deacylation of Ghrelin (1) REACT_19189
TET1,2,3 and TDG demethylate DNA (2) REACT_200682
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (2) REACT_111176
The fatty acid cycling model (1) REACT_6258
Thyroxine biosynthesis (2) REACT_15292
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds (2) REACT_19305
Transport of glycerol from adipocytes to the liver by Aquaporins (1) REACT_23809
Triglyceride Biosynthesis (1) REACT_1190
Tryptophan catabolism (4) REACT_916
Ubiquinol biosynthesis (1) REACT_160111
Urea cycle (1) REACT_847
Utilization of Ketone Bodies (1) REACT_59
VEGFR2 mediated vascular permeability (1) REACT_228016
Vitamin C (ascorbate) metabolism (1) REACT_11202
  logo