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ST001383 Investigating exposures and health impacts of endocrine disrupting chemicals among inner-city children.List of human metabolic pathways and metabolites (REACTOME)
Pathway name (# of metabolites detected in study)
Reactome pathway
Abacavir metabolism (1)
REACT_121388
ABCA transporters in lipid homeostasis (1)
REACT_111158
Abnormal metabolism in phenylketonuria (2)
REACT_121117
Acetylcholine Neurotransmitter Release Cycle (1)
REACT_15309
Activation of gene expression by SREBF (SREBP) (3)
REACT_147904
Agmatine biosynthesis (1)
REACT_14800
alpha-linolenic acid (ALA) metabolism (1)
REACT_121147
Amino acid synthesis and interconversion (transamination) (2)
REACT_238
Amino acid transport across the plasma membrane (7)
REACT_13796
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (7)
REACT_75795
Antigen processing: Ubiquitination & Proteasome degradation (7)
REACT_75842
Arachidonate production from DAG (1)
REACT_19308
Arachidonic acid metabolism (1)
REACT_147851
Astrocytic Glutamate-Glutamine Uptake And Metabolism (1)
REACT_13639
BMAL1:CLOCK,NPAS2 activates circadian gene expression (3)
REACT_111118
Branched-chain amino acid catabolism (1)
REACT_197
Cell surface interactions at the vascular wall (1)
REACT_12051
Cholesterol biosynthesis (1)
REACT_9405
Chylomicron-mediated lipid transport (1)
REACT_6841
Circadian Clock (3)
REACT_24941
Class A/1 (Rhodopsin-like receptors) (5)
REACT_14828
Class C/3 (Metabotropic glutamate/pheromone receptors) (1)
REACT_18319
Class II GLUTs (1)
REACT_19281
Cleavage of the damaged purine (1)
REACT_1729
Conjugation of benzoate with glycine (1)
REACT_6933
Conjugation of phenylacetate with glutamine (2)
REACT_6800
COX reactions (1)
REACT_1396
Creatine metabolism (3)
REACT_813
Cross-presentation of soluble exogenous antigens (endosomes) (7)
REACT_111056
Cytosolic sulfonation of small molecules (4)
REACT_6913
Cytosolic tRNA aminoacylation (7)
REACT_15306
Digestion of dietary lipid (7)
REACT_9518
Endogenous sterols (6)
REACT_13812
Endosomal/Vacuolar pathway (7)
REACT_111168
eNOS activation (2)
REACT_12477
ER-Phagosome pathway (7)
REACT_111178
Fatty acids (2)
REACT_13814
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (3)
REACT_19193
Fatty Acyl-CoA Biosynthesis (1)
REACT_1319
Free fatty acid receptors (6)
REACT_21268
G alpha (i) signalling events (3)
REACT_19231
G alpha (q) signalling events (4)
REACT_18283
G alpha (s) signalling events (4)
REACT_19327
Glucocorticoid biosynthesis (2)
REACT_11036
Glucuronidation (1)
REACT_6784
Glutamate Neurotransmitter Release Cycle (1)
REACT_12591
Glutathione synthesis and recycling (8)
REACT_6960
Glycosphingolipid metabolism (2)
REACT_116105
HDL-mediated lipid transport (1)
REACT_13621
Hedgehog ligand biogenesis (1)
REACT_228111
Heme degradation (2)
REACT_22297
Histidine catabolism (1)
REACT_1249
Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis (1)
REACT_494
Hydrolysis of LPC (1)
REACT_120977
Hydroxycarboxylic acid-binding receptors (2)
REACT_163785
Import of palmitoyl-CoA into the mitochondrial matrix (2)
REACT_11082
Iron uptake and transport (1)
REACT_25060
LDL-mediated lipid transport (1)
REACT_6934
Linoleic acid (LA) metabolism (1)
REACT_121100
Lysosphingolipid and LPA receptors (1)
REACT_18365
Metabolism of serotonin (1)
REACT_15532
Methionine salvage pathway (1)
REACT_75881
Methylation (1)
REACT_6946
Miscellaneous substrates (3)
REACT_13425
Mitochondrial tRNA aminoacylation (7)
REACT_15302
Na+/Cl- dependent neurotransmitter transporters (7)
REACT_20506
Neurotransmitter Clearance In The Synaptic Cleft (1)
REACT_13583
Nicotinate metabolism (1)
REACT_11088
Nitric oxide stimulates guanylate cyclase (1)
REACT_23862
Organic anion transport (3)
REACT_22310
Organic anion transporters (1)
REACT_19372
Organic cation transport (2)
REACT_22357
Orphan transporters (12)
REACT_267716
Phagosomal maturation (early endosomal stage) (1)
REACT_121256
Phenylalanine and tyrosine catabolism (1)
REACT_1786
phospho-PLA2 pathway (1)
REACT_15466
Plasmalogen biosynthesis (1)
REACT_1407
Platelet sensitization by LDL (1)
REACT_23879
PPARA activates gene expression (6)
REACT_116145
Pregnenolone biosynthesis (1)
REACT_11038
Proline catabolism (1)
REACT_1002
Proton-coupled monocarboxylate transport (1)
REACT_20515
Proton-coupled neutral amino acid transporters (1)
REACT_19348
Proton/oligonucleotide cotransporters (7)
REACT_19328
Purine catabolism (3)
REACT_2086
Purine ribonucleoside monophosphate biosynthesis (1)
REACT_1776
Purine salvage (3)
REACT_1923
Pyrimidine biosynthesis (1)
REACT_21376
Pyruvate metabolism (1)
REACT_2071
Recycling of bile acids and salts (7)
REACT_11042
Regulation of cholesterol biosynthesis by SREBP (SREBF) (1)
REACT_147797
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) (3)
REACT_19241
Regulation of pyruvate dehydrogenase (PDH) complex (1)
REACT_12528
Regulation of thyroid hormone activity (1)
REACT_15297
Retinoid cycle disease events (1)
REACT_160130
Retinoid metabolism and transport (3)
REACT_24968
REV-ERBA represses gene expression (3)
REACT_118789
Role of phospholipids in phagocytosis (2)
REACT_160158
RORA activates circadian gene expression (3)
REACT_118659
Scavenging by Class A Receptors (1)
REACT_163699
Scavenging by Class B Receptors (1)
REACT_163679
Scavenging by Class F Receptors (1)
REACT_163813
Scavenging by Class H Receptors (1)
REACT_164002
Scavenging of heme from plasma (1)
REACT_160163
Serotonin and melatonin biosynthesis (1)
REACT_15439
Sphingolipid de novo biosynthesis (2)
REACT_115810
Stimuli-sensing channels (1)
REACT_160189
Synthesis and interconversion of nucleotide di- and triphosphates (1)
REACT_21330
Synthesis of 12-eicosatetraenoic acid derivatives (1)
REACT_150201
Synthesis of 15-eicosatetraenoic acid derivatives (1)
REACT_150422
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) (1)
REACT_150134
Synthesis of 5-eicosatetraenoic acids (1)
REACT_150209
Synthesis of bile acids and bile salts (5)
REACT_11054
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (1)
REACT_11053
Synthesis of bile acids and bile salts via 27-hydroxycholesterol (4)
REACT_11048
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (8)
REACT_11041
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) (1)
REACT_150417
Synthesis of Hepoxilins (HX) and Trioxilins (TrX) (1)
REACT_150292
Synthesis of Leukotrienes (LT) and Eoxins (EX) (1)
REACT_150420
Synthesis of PA (1)
REACT_120906
Synthesis of PC (1)
REACT_121238
Synthesis of PG (1)
REACT_121280
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (1)
REACT_150149
Synthesis of PS (1)
REACT_120823
Synthesis of UDP-N-acetyl-glucosamine (1)
REACT_22394
Synthesis of very long-chain fatty acyl-CoAs (2)
REACT_380
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) (6)
REACT_24019
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) (3)
REACT_23824
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (1)
REACT_111176
The canonical retinoid cycle in rods (twilight vision) (2)
REACT_160156
The retinoid cycle in cones (daylight vision) (1)
REACT_160083
Thyroxine biosynthesis (1)
REACT_15292
Trafficking of dietary sterols (1)
REACT_13781
Transcriptional activation of mitochondrial biogenesis (3)
REACT_200608
Transcriptional regulation of white adipocyte differentiation (3)
REACT_27161
Transport of fatty acids (6)
REACT_23892
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds (2)
REACT_19305
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (3)
REACT_1206
Transport of organic anions (6)
REACT_23988
Tryptophan catabolism (4)
REACT_916
Urea cycle (1)
REACT_847
VEGFR2 mediated cell proliferation (2)
REACT_228024
VEGFR2 mediated vascular permeability (1)
REACT_228016
Vitamins (1)
REACT_13450
YAP1- and WWTR1 (TAZ)-stimulated gene expression (3)
REACT_118713
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