ST001383 Investigating exposures and health impacts of endocrine disrupting chemicals among inner-city children.
List of human metabolic pathways and metabolites (REACTOME)

Pathway name (# of metabolites detected in study)Reactome pathway
Abacavir metabolism (1) REACT_121388
ABCA transporters in lipid homeostasis (1) REACT_111158
Abnormal metabolism in phenylketonuria (2) REACT_121117
Acetylcholine Neurotransmitter Release Cycle (1) REACT_15309
Activation of gene expression by SREBF (SREBP) (3) REACT_147904
Agmatine biosynthesis (1) REACT_14800
alpha-linolenic acid (ALA) metabolism (1) REACT_121147
Amino acid synthesis and interconversion (transamination) (2) REACT_238
Amino acid transport across the plasma membrane (7) REACT_13796
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (7) REACT_75795
Antigen processing: Ubiquitination & Proteasome degradation (7) REACT_75842
Arachidonate production from DAG (1) REACT_19308
Arachidonic acid metabolism (1) REACT_147851
Astrocytic Glutamate-Glutamine Uptake And Metabolism (1) REACT_13639
BMAL1:CLOCK,NPAS2 activates circadian gene expression (3) REACT_111118
Branched-chain amino acid catabolism (1) REACT_197
Cell surface interactions at the vascular wall (1) REACT_12051
Cholesterol biosynthesis (1) REACT_9405
Chylomicron-mediated lipid transport (1) REACT_6841
Circadian Clock (3) REACT_24941
Class A/1 (Rhodopsin-like receptors) (5) REACT_14828
Class C/3 (Metabotropic glutamate/pheromone receptors) (1) REACT_18319
Class II GLUTs (1) REACT_19281
Cleavage of the damaged purine (1) REACT_1729
Conjugation of benzoate with glycine (1) REACT_6933
Conjugation of phenylacetate with glutamine (2) REACT_6800
COX reactions (1) REACT_1396
Creatine metabolism (3) REACT_813
Cross-presentation of soluble exogenous antigens (endosomes) (7) REACT_111056
Cytosolic sulfonation of small molecules (4) REACT_6913
Cytosolic tRNA aminoacylation (7) REACT_15306
Digestion of dietary lipid (7) REACT_9518
Endogenous sterols (6) REACT_13812
Endosomal/Vacuolar pathway (7) REACT_111168
eNOS activation (2) REACT_12477
ER-Phagosome pathway (7) REACT_111178
Fatty acids (2) REACT_13814
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (3) REACT_19193
Fatty Acyl-CoA Biosynthesis (1) REACT_1319
Free fatty acid receptors (6) REACT_21268
G alpha (i) signalling events (3) REACT_19231
G alpha (q) signalling events (4) REACT_18283
G alpha (s) signalling events (4) REACT_19327
Glucocorticoid biosynthesis (2) REACT_11036
Glucuronidation (1) REACT_6784
Glutamate Neurotransmitter Release Cycle (1) REACT_12591
Glutathione synthesis and recycling (8) REACT_6960
Glycosphingolipid metabolism (2) REACT_116105
HDL-mediated lipid transport (1) REACT_13621
Hedgehog ligand biogenesis (1) REACT_228111
Heme degradation (2) REACT_22297
Histidine catabolism (1) REACT_1249
Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis (1) REACT_494
Hydrolysis of LPC (1) REACT_120977
Hydroxycarboxylic acid-binding receptors (2) REACT_163785
Import of palmitoyl-CoA into the mitochondrial matrix (2) REACT_11082
Iron uptake and transport (1) REACT_25060
LDL-mediated lipid transport (1) REACT_6934
Linoleic acid (LA) metabolism (1) REACT_121100
Lysosphingolipid and LPA receptors (1) REACT_18365
Metabolism of serotonin (1) REACT_15532
Methionine salvage pathway (1) REACT_75881
Methylation (1) REACT_6946
Miscellaneous substrates (3) REACT_13425
Mitochondrial tRNA aminoacylation (7) REACT_15302
Na+/Cl- dependent neurotransmitter transporters (7) REACT_20506
Neurotransmitter Clearance In The Synaptic Cleft (1) REACT_13583
Nicotinate metabolism (1) REACT_11088
Nitric oxide stimulates guanylate cyclase (1) REACT_23862
Organic anion transport (3) REACT_22310
Organic anion transporters (1) REACT_19372
Organic cation transport (2) REACT_22357
Orphan transporters (12) REACT_267716
Phagosomal maturation (early endosomal stage) (1) REACT_121256
Phenylalanine and tyrosine catabolism (1) REACT_1786
phospho-PLA2 pathway (1) REACT_15466
Plasmalogen biosynthesis (1) REACT_1407
Platelet sensitization by LDL (1) REACT_23879
PPARA activates gene expression (6) REACT_116145
Pregnenolone biosynthesis (1) REACT_11038
Proline catabolism (1) REACT_1002
Proton-coupled monocarboxylate transport (1) REACT_20515
Proton-coupled neutral amino acid transporters (1) REACT_19348
Proton/oligonucleotide cotransporters (7) REACT_19328
Purine catabolism (3) REACT_2086
Purine ribonucleoside monophosphate biosynthesis (1) REACT_1776
Purine salvage (3) REACT_1923
Pyrimidine biosynthesis (1) REACT_21376
Pyruvate metabolism (1) REACT_2071
Recycling of bile acids and salts (7) REACT_11042
Regulation of cholesterol biosynthesis by SREBP (SREBF) (1) REACT_147797
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) (3) REACT_19241
Regulation of pyruvate dehydrogenase (PDH) complex (1) REACT_12528
Regulation of thyroid hormone activity (1) REACT_15297
Retinoid cycle disease events (1) REACT_160130
Retinoid metabolism and transport (3) REACT_24968
REV-ERBA represses gene expression (3) REACT_118789
Role of phospholipids in phagocytosis (2) REACT_160158
RORA activates circadian gene expression (3) REACT_118659
Scavenging by Class A Receptors (1) REACT_163699
Scavenging by Class B Receptors (1) REACT_163679
Scavenging by Class F Receptors (1) REACT_163813
Scavenging by Class H Receptors (1) REACT_164002
Scavenging of heme from plasma (1) REACT_160163
Serotonin and melatonin biosynthesis (1) REACT_15439
Sphingolipid de novo biosynthesis (2) REACT_115810
Stimuli-sensing channels (1) REACT_160189
Synthesis and interconversion of nucleotide di- and triphosphates (1) REACT_21330
Synthesis of 12-eicosatetraenoic acid derivatives (1) REACT_150201
Synthesis of 15-eicosatetraenoic acid derivatives (1) REACT_150422
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) (1) REACT_150134
Synthesis of 5-eicosatetraenoic acids (1) REACT_150209
Synthesis of bile acids and bile salts (5) REACT_11054
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (1) REACT_11053
Synthesis of bile acids and bile salts via 27-hydroxycholesterol (4) REACT_11048
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (8) REACT_11041
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) (1) REACT_150417
Synthesis of Hepoxilins (HX) and Trioxilins (TrX) (1) REACT_150292
Synthesis of Leukotrienes (LT) and Eoxins (EX) (1) REACT_150420
Synthesis of PA (1) REACT_120906
Synthesis of PC (1) REACT_121238
Synthesis of PG (1) REACT_121280
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (1) REACT_150149
Synthesis of PS (1) REACT_120823
Synthesis of UDP-N-acetyl-glucosamine (1) REACT_22394
Synthesis of very long-chain fatty acyl-CoAs (2) REACT_380
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) (6) REACT_24019
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) (3) REACT_23824
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (1) REACT_111176
The canonical retinoid cycle in rods (twilight vision) (2) REACT_160156
The retinoid cycle in cones (daylight vision) (1) REACT_160083
Thyroxine biosynthesis (1) REACT_15292
Trafficking of dietary sterols (1) REACT_13781
Transcriptional activation of mitochondrial biogenesis (3) REACT_200608
Transcriptional regulation of white adipocyte differentiation (3) REACT_27161
Transport of fatty acids (6) REACT_23892
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds (2) REACT_19305
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (3) REACT_1206
Transport of organic anions (6) REACT_23988
Tryptophan catabolism (4) REACT_916
Urea cycle (1) REACT_847
VEGFR2 mediated cell proliferation (2) REACT_228024
VEGFR2 mediated vascular permeability (1) REACT_228016
Vitamins (1) REACT_13450
YAP1- and WWTR1 (TAZ)-stimulated gene expression (3) REACT_118713
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