ST001823 Alterations in the fecal microbiome and metabolome of horses with antimicrobial-associated diarrhea compared to antibiotic-treated and non-treated healthy case controls
List of human metabolic pathways and metabolites (REACTOME)

Pathway name (# of metabolites detected in study)Reactome pathway
Abnormal metabolism in phenylketonuria (2) REACT_121117
Acetylation (1) REACT_6732
Activation of gene expression by SREBF (SREBP) (1) REACT_147904
alpha-linolenic acid (ALA) metabolism (1) REACT_121147
Amino acid transport across the plasma membrane (2) REACT_13796
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (2) REACT_75795
Antigen processing: Ubiquitination & Proteasome degradation (2) REACT_75842
Biotin transport and metabolism (1) REACT_11153
BMAL1:CLOCK,NPAS2 activates circadian gene expression (1) REACT_111118
Catecholamine biosynthesis (1) REACT_15551
Circadian Clock (1) REACT_24941
Class C/3 (Metabotropic glutamate/pheromone receptors) (1) REACT_18319
Cleavage of the damaged pyrimidine (1) REACT_2156
Cross-presentation of soluble exogenous antigens (endosomes) (2) REACT_111056
Cytosolic tRNA aminoacylation (2) REACT_15306
Defective HLCS causes multiple carboxylase deficiency (1) REACT_169312
Endosomal/Vacuolar pathway (2) REACT_111168
ER-Phagosome pathway (2) REACT_111178
Free fatty acid receptors (1) REACT_21268
Gluconeogenesis (1) REACT_1520
Glutathione synthesis and recycling (2) REACT_6960
Metabolism of polyamines (1) REACT_14820
Metabolism of serotonin (1) REACT_15532
Methionine salvage pathway (1) REACT_75881
Miscellaneous substrates (2) REACT_13425
Mitochondrial tRNA aminoacylation (2) REACT_15302
Na+/Cl- dependent neurotransmitter transporters (2) REACT_20506
Orphan transporters (1) REACT_267716
Phenylalanine and tyrosine catabolism (2) REACT_1786
PPARA activates gene expression (1) REACT_116145
Proton/oligonucleotide cotransporters (2) REACT_19328
Purine catabolism (2) REACT_2086
Purine salvage (2) REACT_1923
Pyrimidine catabolism (2) REACT_1023
Pyrimidine salvage reactions (2) REACT_655
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) (1) REACT_19241
REV-ERBA represses gene expression (1) REACT_118789
RORA activates circadian gene expression (1) REACT_118659
Serotonin and melatonin biosynthesis (1) REACT_15439
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) (1) REACT_24019
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (1) REACT_111176
Thyroxine biosynthesis (1) REACT_15292
Transcriptional activation of mitochondrial biogenesis (1) REACT_200608
Transcriptional regulation of white adipocyte differentiation (1) REACT_27161
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (3) REACT_1206
Transport of vitamins, nucleosides, and related molecules (1) REACT_22285
Tryptophan catabolism (2) REACT_916
YAP1- and WWTR1 (TAZ)-stimulated gene expression (1) REACT_118713
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