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ST001823 Alterations in the fecal microbiome and metabolome of horses with antimicrobial-associated diarrhea compared to antibiotic-treated and non-treated healthy case controlsList of human metabolic pathways and metabolites (REACTOME)
Pathway name (# of metabolites detected in study)
Reactome pathway
Abnormal metabolism in phenylketonuria (2)
REACT_121117
Acetylation (1)
REACT_6732
Activation of gene expression by SREBF (SREBP) (1)
REACT_147904
alpha-linolenic acid (ALA) metabolism (1)
REACT_121147
Amino acid transport across the plasma membrane (2)
REACT_13796
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (2)
REACT_75795
Antigen processing: Ubiquitination & Proteasome degradation (2)
REACT_75842
Biotin transport and metabolism (1)
REACT_11153
BMAL1:CLOCK,NPAS2 activates circadian gene expression (1)
REACT_111118
Catecholamine biosynthesis (1)
REACT_15551
Circadian Clock (1)
REACT_24941
Class C/3 (Metabotropic glutamate/pheromone receptors) (1)
REACT_18319
Cleavage of the damaged pyrimidine (1)
REACT_2156
Cross-presentation of soluble exogenous antigens (endosomes) (2)
REACT_111056
Cytosolic tRNA aminoacylation (2)
REACT_15306
Defective HLCS causes multiple carboxylase deficiency (1)
REACT_169312
Endosomal/Vacuolar pathway (2)
REACT_111168
ER-Phagosome pathway (2)
REACT_111178
Free fatty acid receptors (1)
REACT_21268
Gluconeogenesis (1)
REACT_1520
Glutathione synthesis and recycling (2)
REACT_6960
Metabolism of polyamines (1)
REACT_14820
Metabolism of serotonin (1)
REACT_15532
Methionine salvage pathway (1)
REACT_75881
Miscellaneous substrates (2)
REACT_13425
Mitochondrial tRNA aminoacylation (2)
REACT_15302
Na+/Cl- dependent neurotransmitter transporters (2)
REACT_20506
Orphan transporters (1)
REACT_267716
Phenylalanine and tyrosine catabolism (2)
REACT_1786
PPARA activates gene expression (1)
REACT_116145
Proton/oligonucleotide cotransporters (2)
REACT_19328
Purine catabolism (2)
REACT_2086
Purine salvage (2)
REACT_1923
Pyrimidine catabolism (2)
REACT_1023
Pyrimidine salvage reactions (2)
REACT_655
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) (1)
REACT_19241
REV-ERBA represses gene expression (1)
REACT_118789
RORA activates circadian gene expression (1)
REACT_118659
Serotonin and melatonin biosynthesis (1)
REACT_15439
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) (1)
REACT_24019
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (1)
REACT_111176
Thyroxine biosynthesis (1)
REACT_15292
Transcriptional activation of mitochondrial biogenesis (1)
REACT_200608
Transcriptional regulation of white adipocyte differentiation (1)
REACT_27161
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (3)
REACT_1206
Transport of vitamins, nucleosides, and related molecules (1)
REACT_22285
Tryptophan catabolism (2)
REACT_916
YAP1- and WWTR1 (TAZ)-stimulated gene expression (1)
REACT_118713
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