ST001955 Metabonomics analysis reveals the physiological mechanism of promoting maize shoots growth under negative pressure to stabilize soil water content
List of human metabolic pathways and metabolites (REACTOME)

Pathway name (# of metabolites detected in study)Reactome pathway
ABH2 mediated Reversal of Alkylation Damage (3) REACT_526
ABH3 mediated Reversal of Alkylation Damage (3) REACT_1662
Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate (1) REACT_160183
Abnormal metabolism in phenylketonuria (3) REACT_121117
Acetylcholine Neurotransmitter Release Cycle (2) REACT_15309
Acetylcholine regulates insulin secretion (1) REACT_18405
Activation of AMPA receptors (1) REACT_18338
Activation of Ca-permeable Kainate Receptor (1) REACT_21346
Activation of gene expression by SREBF (SREBP) (4) REACT_147904
Activation of Na-permeable Kainate Receptors (1) REACT_21343
Activation of the phototransduction cascade (1) REACT_163932
Adenylate cyclase activating pathway (1) REACT_15312
Aflatoxin activation and detoxification (2) REACT_228214
Agmatine biosynthesis (2) REACT_14800
alpha-linolenic acid (ALA) metabolism (1) REACT_121147
Alpha-oxidation of phytanate (2) REACT_17003
Amino acid synthesis and interconversion (transamination) (6) REACT_238
Amino acid transport across the plasma membrane (17) REACT_13796
Androgen biosynthesis (1) REACT_11059
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (16) REACT_75795
Antigen processing: Ubiquitination & Proteasome degradation (16) REACT_75842
Arachidonate production from DAG (1) REACT_19308
Arachidonic acid metabolism (1) REACT_147851
Astrocytic Glutamate-Glutamine Uptake And Metabolism (2) REACT_13639
Beta-oxidation of pristanoyl-CoA (1) REACT_17017
Beta-oxidation of very long chain fatty acids (1) REACT_17062
Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB (1) REACT_416
Biotin transport and metabolism (1) REACT_11153
BMAL1:CLOCK,NPAS2 activates circadian gene expression (4) REACT_111118
Branched-chain amino acid catabolism (4) REACT_197
Ca2+ pathway (1) REACT_172761
Cam-PDE 1 activation (1) REACT_15408
Carnitine synthesis (2) REACT_2125
Catecholamine biosynthesis (2) REACT_15551
cGMP effects (1) REACT_23767
Circadian Clock (4) REACT_24941
Citric acid cycle (TCA cycle) (3) REACT_1785
Class A/1 (Rhodopsin-like receptors) (2) REACT_14828
Class C/3 (Metabotropic glutamate/pheromone receptors) (7) REACT_18319
Cleavage of the damaged pyrimidine (2) REACT_2156
Cobalamin (Cbl, vitamin B12) transport and metabolism (2) REACT_163862
Coenzyme A biosynthesis (1) REACT_11218
Collagen biosynthesis and modifying enzymes (3) REACT_121139
Condensation of Prophase Chromosomes (2) REACT_172744
Conjugation of phenylacetate with glutamine (1) REACT_6800
COX reactions (1) REACT_1396
Creatine metabolism (1) REACT_813
CREB phosphorylation through the activation of Adenylate Cyclase (1) REACT_20625
CREB phosphorylation through the activation of CaMKII (1) REACT_20642
Cross-presentation of soluble exogenous antigens (endosomes) (16) REACT_111056
CYP2E1 reactions (2) REACT_13797
Cysteine formation from homocysteine (1) REACT_115589
Cytosolic iron-sulfur cluster assembly (1) REACT_160176
Cytosolic sulfonation of small molecules (2) REACT_6913
Cytosolic tRNA aminoacylation (16) REACT_15306
DARPP-32 events (1) REACT_15334
Defective MTR causes methylmalonic aciduria and homocystinuria type cblG (1) REACT_169149
Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE (1) REACT_169439
Degradation of cysteine and homocysteine (1) REACT_115654
Degradation of GABA (3) REACT_23964
Digestion of dietary carbohydrate (2) REACT_9472
Digestion of dietary lipid (1) REACT_9518
Endogenous sterols (2) REACT_13812
Endosomal/Vacuolar pathway (16) REACT_111168
eNOS activation (3) REACT_12477
EPHB-mediated forward signaling (1) REACT_228085
ER-Phagosome pathway (16) REACT_111178
Ethanol oxidation (2) REACT_34
Fatty acids (1) REACT_13814
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (3) REACT_19193
Fatty Acyl-CoA Biosynthesis (2) REACT_1319
Free fatty acid receptors (5) REACT_21268
Fructose catabolism (1) REACT_1571
GABA synthesis (1) REACT_24020
G alpha (i) signalling events (8) REACT_19231
G alpha (q) signalling events (8) REACT_18283
G alpha (s) signalling events (1) REACT_19327
G alpha (z) signalling events (1) REACT_19333
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (1) REACT_18274
Glucocorticoid biosynthesis (1) REACT_11036
Gluconeogenesis (4) REACT_1520
Glucuronidation (1) REACT_6784
Glutamate Neurotransmitter Release Cycle (2) REACT_12591
Glutathione synthesis and recycling (17) REACT_6960
Glycolysis (2) REACT_1383
Glycosphingolipid metabolism (1) REACT_116105
Glyoxylate metabolism (1) REACT_16925
HCN channels (1) REACT_75862
HDMs demethylate histones (2) REACT_228178
Hedgehog 'off' state (1) REACT_267634
Highly calcium permeable nicotinic acetylcholine receptors (1) REACT_22352
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors (1) REACT_22303
Highly sodium permeable acetylcholine nicotinic receptors (1) REACT_22223
Histidine catabolism (2) REACT_1249
HS-GAG biosynthesis (1) REACT_121248
HS-GAG degradation (1) REACT_120752
Hydrolysis of LPC (1) REACT_120977
Hydroxycarboxylic acid-binding receptors (1) REACT_163785
Inactivation, recovery and regulation of the phototransduction cascade (2) REACT_163919
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate (1) REACT_25367
Linoleic acid (LA) metabolism (1) REACT_121100
Lysine catabolism (3) REACT_1298
Metabolism of folate and pterines (2) REACT_11167
Metabolism of polyamines (1) REACT_14820
Methionine salvage pathway (3) REACT_75881
Methylation (2) REACT_6946
Mineralocorticoid biosynthesis (1) REACT_11047
Miscellaneous substrates (1) REACT_13425
Mitochondrial tRNA aminoacylation (16) REACT_15302
Molybdenum cofactor biosynthesis (1) REACT_25073
Muscarinic acetylcholine receptors (1) REACT_16943
Na+/Cl- dependent neurotransmitter transporters (15) REACT_20506
NADPH regeneration (1) REACT_16904
Neurotransmitter Clearance In The Synaptic Cleft (2) REACT_13583
Nicotinate metabolism (2) REACT_11088
Nitric oxide stimulates guanylate cyclase (2) REACT_23862
NoRC negatively regulates rRNA expression (1) REACT_200856
NOSIP mediated eNOS trafficking (1) REACT_12510
NOSTRIN mediated eNOS trafficking (1) REACT_12541
Organic anion transport (1) REACT_22310
Organic anion transporters (2) REACT_19372
Organic cation transport (2) REACT_22357
Orphan transporters (4) REACT_267716
Oxidative Stress Induced Senescence (2) REACT_169436
Oxygen-dependent asparagine hydroxylation of Hypoxia-inducible Factor Alpha (2) REACT_121226
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (2) REACT_120916
PDE3B signalling (1) REACT_1451
Phagosomal maturation (early endosomal stage) (1) REACT_121256
Phenylalanine and tyrosine catabolism (4) REACT_1786
phospho-PLA2 pathway (1) REACT_15466
PKA activation (1) REACT_15530
PKA activation in glucagon signalling (1) REACT_1946
Plasmalogen biosynthesis (1) REACT_1407
PPARA activates gene expression (4) REACT_116145
Presynaptic function of Kainate receptors (1) REACT_21254
Proline catabolism (2) REACT_1002
Proton-coupled neutral amino acid transporters (1) REACT_19348
Proton/oligonucleotide cotransporters (16) REACT_19328
Purine catabolism (4) REACT_2086
Purine ribonucleoside monophosphate biosynthesis (3) REACT_1776
Purine salvage (5) REACT_1923
Pyrimidine biosynthesis (4) REACT_21376
Pyrimidine catabolism (7) REACT_1023
Pyrimidine salvage reactions (6) REACT_655
Rap1 signalling (1) REACT_23898
Ras activation uopn Ca2+ infux through NMDA receptor (1) REACT_20546
Regulation of insulin secretion (1) REACT_18325
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) (4) REACT_19241
Respiratory electron transport (1) REACT_22393
Retinoid cycle disease events (1) REACT_160130
Retinoid metabolism and transport (3) REACT_24968
Reuptake of GABA (1) REACT_23910
REV-ERBA represses gene expression (4) REACT_118789
Role of phospholipids in phagocytosis (2) REACT_160158
RORA activates circadian gene expression (4) REACT_118659
Serine biosynthesis (3) REACT_115789
Serotonin and melatonin biosynthesis (1) REACT_15439
Sodium-coupled sulphate, di- and tri-carboxylate transporters (2) REACT_20646
Sphingolipid de novo biosynthesis (3) REACT_115810
Sulfur amino acid metabolism (4) REACT_115639
Synthesis and interconversion of nucleotide di- and triphosphates (2) REACT_21330
Synthesis of 12-eicosatetraenoic acid derivatives (1) REACT_150201
Synthesis of 15-eicosatetraenoic acid derivatives (1) REACT_150422
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) (2) REACT_150134
Synthesis of 5-eicosatetraenoic acids (1) REACT_150209
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) (1) REACT_150417
Synthesis of glycosylphosphatidylinositol (GPI) (1) REACT_952
Synthesis of Hepoxilins (HX) and Trioxilins (TrX) (1) REACT_150292
Synthesis of IP2, IP, and Ins in the cytosol (1) REACT_150352
Synthesis of Leukotrienes (LT) and Eoxins (EX) (2) REACT_150420
Synthesis of PA (1) REACT_120906
Synthesis of PC (2) REACT_121238
Synthesis of PG (1) REACT_121280
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (1) REACT_150149
Synthesis of PS (2) REACT_120823
Synthesis of UDP-N-acetyl-glucosamine (2) REACT_22394
Synthesis of very long-chain fatty acyl-CoAs (2) REACT_380
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) (5) REACT_24019
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) (3) REACT_23824
TET1,2,3 and TDG demethylate DNA (3) REACT_200682
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (3) REACT_111176
The canonical retinoid cycle in rods (twilight vision) (3) REACT_160156
The retinoid cycle in cones (daylight vision) (1) REACT_160083
Thyroxine biosynthesis (2) REACT_15292
Transcriptional activation of mitochondrial biogenesis (4) REACT_200608
Transcriptional regulation of white adipocyte differentiation (4) REACT_27161
Transport of fatty acids (3) REACT_23892
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds (1) REACT_19305
Transport of inorganic cations/anions and amino acids/oligopeptides (2) REACT_19397
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (10) REACT_1206
Tryptophan catabolism (6) REACT_916
Ubiquinol biosynthesis (1) REACT_160111
Unblocking of NMDA receptor, glutamate binding and activation (1) REACT_20594
Uptake and function of anthrax toxins (1) REACT_228255
Urea cycle (3) REACT_847
Utilization of Ketone Bodies (1) REACT_59
Vasopressin regulates renal water homeostasis via Aquaporins (1) REACT_24023
VEGFR2 mediated cell proliferation (1) REACT_228024
VEGFR2 mediated vascular permeability (2) REACT_228016
Vitamin B2 (riboflavin) metabolism (2) REACT_11070
Vitamin C (ascorbate) metabolism (1) REACT_11202
Vitamins B6 activation to pyridoxal phosphate (2) REACT_25012
Xenobiotics (1) REACT_13543
YAP1- and WWTR1 (TAZ)-stimulated gene expression (4) REACT_118713
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