ST002283 The “ForensOMICS” approach to forensic post-mortem interval estimation: combining metabolomics, lipidomics and proteomics for the analysis human skeletal remains
List of human metabolic pathways and metabolites (REACTOME)

Pathway name (# of metabolites detected in study)Reactome pathway
Abacavir metabolism (1) REACT_121388
Abnormal metabolism in phenylketonuria (1) REACT_121117
Acetylcholine Neurotransmitter Release Cycle (2) REACT_15309
Acetylcholine regulates insulin secretion (1) REACT_18405
Activation of gene expression by SREBF (SREBP) (3) REACT_147904
Adenosine P1 receptors (1) REACT_18288
Amino acid transport across the plasma membrane (3) REACT_13796
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (1) REACT_75795
Antigen processing: Ubiquitination & Proteasome degradation (1) REACT_75842
Arachidonate production from DAG (1) REACT_19308
Arachidonic acid metabolism (1) REACT_147851
Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 (1) REACT_13721
BMAL1:CLOCK,NPAS2 activates circadian gene expression (3) REACT_111118
Circadian Clock (3) REACT_24941
Class A/1 (Rhodopsin-like receptors) (1) REACT_14828
Class C/3 (Metabotropic glutamate/pheromone receptors) (3) REACT_18319
Class II GLUTs (1) REACT_19281
Cleavage of the damaged purine (1) REACT_1729
Cleavage of the damaged pyrimidine (1) REACT_2156
Conjugation of salicylate with glycine (1) REACT_6812
COX reactions (1) REACT_1396
Creatine metabolism (2) REACT_813
Cross-presentation of soluble exogenous antigens (endosomes) (1) REACT_111056
Cytosolic tRNA aminoacylation (1) REACT_15306
degradation of AXIN (1) REACT_200766
Degradation of cysteine and homocysteine (1) REACT_115654
Digestion of dietary carbohydrate (2) REACT_9472
Digestion of dietary lipid (1) REACT_9518
Downregulation of SMAD2/3:SMAD4 transcriptional activity (1) REACT_121111
Endosomal/Vacuolar pathway (1) REACT_111168
eNOS activation (1) REACT_12477
ER-Phagosome pathway (1) REACT_111178
Fatty acids (2) REACT_13814
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (2) REACT_19193
Fatty Acyl-CoA Biosynthesis (1) REACT_1319
Free fatty acid receptors (5) REACT_21268
G alpha (i) signalling events (5) REACT_19231
G alpha (q) signalling events (4) REACT_18283
G alpha (s) signalling events (2) REACT_19327
Glutathione synthesis and recycling (1) REACT_6960
Highly calcium permeable nicotinic acetylcholine receptors (1) REACT_22352
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors (1) REACT_22303
Highly sodium permeable acetylcholine nicotinic receptors (1) REACT_22223
Histamine receptors (1) REACT_16903
Histidine catabolism (2) REACT_1249
Hydrolysis of LPC (1) REACT_120977
Hydroxycarboxylic acid-binding receptors (1) REACT_163785
Import of palmitoyl-CoA into the mitochondrial matrix (1) REACT_11082
Linoleic acid (LA) metabolism (1) REACT_121100
Methionine salvage pathway (1) REACT_75881
Methylation (1) REACT_6946
Miscellaneous substrates (1) REACT_13425
Mitochondrial tRNA aminoacylation (1) REACT_15302
Muscarinic acetylcholine receptors (1) REACT_16943
Na+/Cl- dependent neurotransmitter transporters (4) REACT_20506
Neurotransmitter Clearance In The Synaptic Cleft (2) REACT_13583
NGF-independant TRKA activation (1) REACT_11046
Nicotinamide salvaging (1) REACT_11213
Organic anion transport (1) REACT_22310
Organic cation transport (3) REACT_22357
Orphan transporters (3) REACT_267716
Phenylalanine and tyrosine catabolism (1) REACT_1786
phospho-PLA2 pathway (1) REACT_15466
Plasmalogen biosynthesis (1) REACT_1407
PPARA activates gene expression (3) REACT_116145
Proton/oligonucleotide cotransporters (1) REACT_19328
Purine catabolism (5) REACT_2086
Purine salvage (4) REACT_1923
Pyrimidine biosynthesis (1) REACT_21376
Pyrimidine catabolism (1) REACT_1023
Pyrimidine salvage reactions (1) REACT_655
Recycling of bile acids and salts (1) REACT_11042
Regulation of HSF1-mediated heat shock response (1) REACT_200780
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) (3) REACT_19241
Respiratory electron transport (1) REACT_22393
Retinoid cycle disease events (1) REACT_160130
Retinoid metabolism and transport (3) REACT_24968
Reuptake of GABA (1) REACT_23910
REV-ERBA represses gene expression (3) REACT_118789
Role of phospholipids in phagocytosis (2) REACT_160158
RORA activates circadian gene expression (3) REACT_118659
SIRT1 negatively regulates rRNA Expression (1) REACT_200827
Stimuli-sensing channels (1) REACT_160189
Sulfide oxidation to sulfate (1) REACT_116010
Sulfur amino acid metabolism (2) REACT_115639
Synthesis of 12-eicosatetraenoic acid derivatives (1) REACT_150201
Synthesis of 15-eicosatetraenoic acid derivatives (1) REACT_150422
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) (1) REACT_150134
Synthesis of 5-eicosatetraenoic acids (1) REACT_150209
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (1) REACT_11041
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) (1) REACT_150417
Synthesis of Hepoxilins (HX) and Trioxilins (TrX) (1) REACT_150292
Synthesis of Leukotrienes (LT) and Eoxins (EX) (2) REACT_150420
Synthesis of PA (1) REACT_120906
Synthesis of PC (2) REACT_121238
Synthesis of PG (1) REACT_121280
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (3) REACT_150149
Synthesis of PS (1) REACT_120823
Synthesis of very long-chain fatty acyl-CoAs (2) REACT_380
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) (6) REACT_24019
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) (2) REACT_23824
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (1) REACT_111176
The canonical retinoid cycle in rods (twilight vision) (3) REACT_160156
The retinoid cycle in cones (daylight vision) (1) REACT_160083
Transcriptional activation of mitochondrial biogenesis (3) REACT_200608
Transcriptional regulation of white adipocyte differentiation (3) REACT_27161
Transport of fatty acids (4) REACT_23892
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds (2) REACT_19305
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (6) REACT_1206
Tryptophan catabolism (2) REACT_916
Xenobiotics (1) REACT_13543
YAP1- and WWTR1 (TAZ)-stimulated gene expression (3) REACT_118713
  logo