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ST002391 Evaluation of Two Simultaneous Metabolomic and Proteomic Extraction Protocols Assessed by Ultra-High-Performance Liq-uid Chromatography Tandem Mass SpectrometryList of human metabolic pathways and metabolites (REACTOME)
Pathway name (# of metabolites detected in study)
Reactome pathway
ABH2 mediated Reversal of Alkylation Damage (1)
REACT_526
ABH3 mediated Reversal of Alkylation Damage (1)
REACT_1662
Abnormal metabolism in phenylketonuria (3)
REACT_121117
Activation of gene expression by SREBF (SREBP) (1)
REACT_147904
Acyl chain remodeling of DAG and TAG (1)
REACT_121122
Aflatoxin activation and detoxification (1)
REACT_228214
Amino acid synthesis and interconversion (transamination) (3)
REACT_238
Amino acid transport across the plasma membrane (8)
REACT_13796
Androgen biosynthesis (1)
REACT_11059
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (9)
REACT_75795
Antigen processing: Ubiquitination & Proteasome degradation (9)
REACT_75842
Arachidonate production from DAG (1)
REACT_19308
Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 (1)
REACT_13721
Astrocytic Glutamate-Glutamine Uptake And Metabolism (1)
REACT_13639
Beta-oxidation of pristanoyl-CoA (1)
REACT_17017
Beta-oxidation of very long chain fatty acids (1)
REACT_17062
Biotin transport and metabolism (1)
REACT_11153
BMAL1:CLOCK,NPAS2 activates circadian gene expression (1)
REACT_111118
Branched-chain amino acid catabolism (3)
REACT_197
Catecholamine biosynthesis (1)
REACT_15551
Circadian Clock (1)
REACT_24941
Class C/3 (Metabotropic glutamate/pheromone receptors) (2)
REACT_18319
Class II GLUTs (1)
REACT_19281
Cleavage of the damaged pyrimidine (1)
REACT_2156
Cobalamin (Cbl, vitamin B12) transport and metabolism (1)
REACT_163862
Conjugation of phenylacetate with glutamine (1)
REACT_6800
Creatine metabolism (1)
REACT_813
Cross-presentation of soluble exogenous antigens (endosomes) (9)
REACT_111056
CYP2E1 reactions (2)
REACT_13797
Cytosolic sulfonation of small molecules (2)
REACT_6913
Cytosolic tRNA aminoacylation (9)
REACT_15306
Digestion of dietary lipid (1)
REACT_9518
Endosomal/Vacuolar pathway (9)
REACT_111168
ER-Phagosome pathway (9)
REACT_111178
Ethanol oxidation (2)
REACT_34
FMO oxidises nucleophiles (1)
REACT_13653
Free fatty acid receptors (1)
REACT_21268
G alpha (i) signalling events (1)
REACT_19231
G alpha (q) signalling events (2)
REACT_18283
Gluconeogenesis (1)
REACT_1520
Glucuronidation (1)
REACT_6784
Glutamate Neurotransmitter Release Cycle (1)
REACT_12591
Glutathione synthesis and recycling (10)
REACT_6960
Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis (1)
REACT_494
HS-GAG biosynthesis (1)
REACT_121248
HS-GAG degradation (1)
REACT_120752
Hydrolysis of LPE (1)
REACT_120785
Inactivation, recovery and regulation of the phototransduction cascade (1)
REACT_163919
Linoleic acid (LA) metabolism (1)
REACT_121100
Lysine catabolism (2)
REACT_1298
Metabolism of polyamines (1)
REACT_14820
Metabolism of serotonin (1)
REACT_15532
Methionine salvage pathway (2)
REACT_75881
Methylation (2)
REACT_6946
Mitochondrial tRNA aminoacylation (9)
REACT_15302
Molybdenum cofactor biosynthesis (1)
REACT_25073
Na+/Cl- dependent neurotransmitter transporters (8)
REACT_20506
Nicotinate metabolism (1)
REACT_11088
NoRC negatively regulates rRNA expression (1)
REACT_200856
Organic anion transport (1)
REACT_22310
Organic anion transporters (1)
REACT_19372
Orphan transporters (1)
REACT_267716
Passive transport by Aquaporins (1)
REACT_23826
Phenylalanine and tyrosine catabolism (2)
REACT_1786
PPARA activates gene expression (1)
REACT_116145
Proline catabolism (1)
REACT_1002
Proton-coupled neutral amino acid transporters (1)
REACT_19348
Proton/oligonucleotide cotransporters (9)
REACT_19328
Purine catabolism (1)
REACT_2086
Purine ribonucleoside monophosphate biosynthesis (2)
REACT_1776
Pyrimidine biosynthesis (2)
REACT_21376
Pyrimidine catabolism (2)
REACT_1023
Pyrimidine salvage reactions (2)
REACT_655
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) (1)
REACT_19241
Retinoid metabolism and transport (1)
REACT_24968
REV-ERBA represses gene expression (1)
REACT_118789
RORA activates circadian gene expression (1)
REACT_118659
Serotonin and melatonin biosynthesis (1)
REACT_15439
Sphingolipid de novo biosynthesis (1)
REACT_115810
Stimuli-sensing channels (1)
REACT_160189
Sulfur amino acid metabolism (1)
REACT_115639
Synthesis and interconversion of nucleotide di- and triphosphates (1)
REACT_21330
Synthesis of glycosylphosphatidylinositol (GPI) (1)
REACT_952
Synthesis of PE (1)
REACT_120919
Synthesis of PG (1)
REACT_121280
Synthesis of PS (1)
REACT_120823
Synthesis of UDP-N-acetyl-glucosamine (1)
REACT_22394
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (1)
REACT_111176
The canonical retinoid cycle in rods (twilight vision) (1)
REACT_160156
Transcriptional activation of mitochondrial biogenesis (1)
REACT_200608
Transcriptional regulation of white adipocyte differentiation (1)
REACT_27161
Transport of fatty acids (1)
REACT_23892
Transport of glycerol from adipocytes to the liver by Aquaporins (1)
REACT_23809
Transport of inorganic cations/anions and amino acids/oligopeptides (1)
REACT_19397
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (2)
REACT_1206
Triglyceride Biosynthesis (1)
REACT_1190
Tryptophan catabolism (4)
REACT_916
Urea cycle (1)
REACT_847
Xenobiotics (1)
REACT_13543
YAP1- and WWTR1 (TAZ)-stimulated gene expression (1)
REACT_118713
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