ST002701 Mouse serum metabolomics
List of human metabolic pathways and metabolites (REACTOME)

Pathway name (# of metabolites detected in study)Reactome pathway
Abnormal metabolism in phenylketonuria (2) REACT_121117
Acetylcholine Neurotransmitter Release Cycle (2) REACT_15309
Acetylcholine regulates insulin secretion (1) REACT_18405
Agmatine biosynthesis (1) REACT_14800
Amino acid synthesis and interconversion (transamination) (1) REACT_238
Amino acid transport across the plasma membrane (9) REACT_13796
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (8) REACT_75795
Antigen processing: Ubiquitination & Proteasome degradation (8) REACT_75842
Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 (1) REACT_13721
Branched-chain amino acid catabolism (1) REACT_197
Catecholamine biosynthesis (1) REACT_15551
Class A/1 (Rhodopsin-like receptors) (1) REACT_14828
Class C/3 (Metabotropic glutamate/pheromone receptors) (2) REACT_18319
Cleavage of the damaged pyrimidine (1) REACT_2156
Cobalamin (Cbl, vitamin B12) transport and metabolism (1) REACT_163862
Creatine metabolism (1) REACT_813
Cross-presentation of soluble exogenous antigens (endosomes) (8) REACT_111056
CYP2E1 reactions (1) REACT_13797
Cytosolic tRNA aminoacylation (8) REACT_15306
Degradation of cysteine and homocysteine (1) REACT_115654
Eicosanoids (1) REACT_13645
Endogenous sterols (1) REACT_13812
Endosomal/Vacuolar pathway (8) REACT_111168
eNOS activation (1) REACT_12477
ER-Phagosome pathway (8) REACT_111178
G alpha (i) signalling events (4) REACT_19231
G alpha (q) signalling events (3) REACT_18283
G alpha (s) signalling events (2) REACT_19327
Glutathione synthesis and recycling (8) REACT_6960
Highly calcium permeable nicotinic acetylcholine receptors (1) REACT_22352
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors (1) REACT_22303
Highly sodium permeable acetylcholine nicotinic receptors (1) REACT_22223
Histamine receptors (1) REACT_16903
Histidine catabolism (2) REACT_1249
Hydrolysis of LPC (1) REACT_120977
Hypusine synthesis from eIF5A-lysine (1) REACT_12469
Inactivation, recovery and regulation of the phototransduction cascade (1) REACT_163919
Interconversion of polyamines (2) REACT_14805
Metabolism of polyamines (1) REACT_14820
Metabolism of serotonin (1) REACT_15532
Methionine salvage pathway (1) REACT_75881
Methylation (1) REACT_6946
Miscellaneous substrates (1) REACT_13425
Mitochondrial tRNA aminoacylation (8) REACT_15302
Molybdenum cofactor biosynthesis (1) REACT_25073
Muscarinic acetylcholine receptors (1) REACT_16943
Na+/Cl- dependent neurotransmitter transporters (10) REACT_20506
Neurotransmitter Clearance In The Synaptic Cleft (2) REACT_13583
Nicotinamide salvaging (1) REACT_11213
Nitric oxide stimulates guanylate cyclase (1) REACT_23862
Organic cation transport (3) REACT_22357
PAOs oxidise polyamines to amines (2) REACT_505
Phagosomal maturation (early endosomal stage) (1) REACT_121256
Phenylalanine and tyrosine catabolism (2) REACT_1786
PPARA activates gene expression (1) REACT_116145
Proline catabolism (1) REACT_1002
Prostacyclin signalling through prostacyclin receptor (1) REACT_23946
Prostanoid ligand receptors (1) REACT_18425
Proton-coupled neutral amino acid transporters (1) REACT_19348
Proton/oligonucleotide cotransporters (8) REACT_19328
Pyrimidine catabolism (2) REACT_1023
Pyrimidine salvage reactions (2) REACT_655
Recycling of bile acids and salts (1) REACT_11042
Role of phospholipids in phagocytosis (1) REACT_160158
Serotonin and melatonin biosynthesis (2) REACT_15439
Sulfur amino acid metabolism (1) REACT_115639
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (1) REACT_11041
Synthesis of PA (1) REACT_120906
Synthesis of PC (2) REACT_121238
Synthesis of PG (1) REACT_121280
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (1) REACT_150149
Synthesis of PS (1) REACT_120823
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) (1) REACT_24019
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (1) REACT_111176
Thyroxine biosynthesis (1) REACT_15292
Transcriptional regulation of white adipocyte differentiation (1) REACT_27161
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds (1) REACT_19305
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (2) REACT_1206
Tryptophan catabolism (2) REACT_916
Urea cycle (1) REACT_847
VEGFR2 mediated vascular permeability (1) REACT_228016
Vitamin B1 (thiamin) metabolism (1) REACT_11117
Vitamin B2 (riboflavin) metabolism (1) REACT_11070
Vitamin D (calciferol) metabolism (1) REACT_13523
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