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Return to Statistics Toolbox
Volcano Plot analysis for Study ST002453
(Analysis All analyses used)
Select one or more experimental factors for Groups 1 and 2. The members of each group should be DIFFERENT.
Group1
Experimental factor
Group2
Brain Region:Cerebral Nuclei | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months (3)
Brain Region:Cerebral Nuclei | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months (3)
Brain Region:Cerebral Nuclei | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months (3)
Brain Region:Cerebral Nuclei | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months (3)
Brain Region:Cerebral Nuclei | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months (3)
Brain Region:Cerebral Nuclei | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months (3)
Brain Region:Cortical Subplate | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months (3)
Brain Region:Cortical Subplate | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months (3)
Brain Region:Cortical Subplate | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months (3)
Brain Region:Cortical Subplate | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months (3)
Brain Region:Cortical Subplate | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months (3)
Brain Region:Cortical Subplate | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months (3)
Brain Region:Fiber Tracts | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months (3)
Brain Region:Fiber Tracts | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months (3)
Brain Region:Fiber Tracts | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months (3)
Brain Region:Fiber Tracts | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months (3)
Brain Region:Fiber Tracts | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months (3)
Brain Region:Fiber Tracts | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months (3)
Brain Region:Hippocampus | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months (3)
Brain Region:Hippocampus | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months (3)
Brain Region:Hippocampus | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months (3)
Brain Region:Hippocampus | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months (3)
Brain Region:Hippocampus | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months (3)
Brain Region:Hippocampus | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months (3)
Brain Region:Hypothalamus | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months (3)
Brain Region:Hypothalamus | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months (3)
Brain Region:Hypothalamus | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months (3)
Brain Region:Hypothalamus | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months (3)
Brain Region:Hypothalamus | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months (3)
Brain Region:Hypothalamus | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months (3)
Brain Region:Iso Cortex | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months (3)
Brain Region:Iso Cortex | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months (3)
Brain Region:Iso Cortex | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months (3)
Brain Region:Iso Cortex | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months (3)
Brain Region:Iso Cortex | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months (3)
Brain Region:Iso Cortex | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months (3)
Brain Region:Olfact. Area | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months (3)
Brain Region:Olfact. Area | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months (3)
Brain Region:Olfact. Area | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months (3)
Brain Region:Olfact. Area | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months (3)
Brain Region:Olfact. Area | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months (3)
Brain Region:Olfact. Area | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months (3)
Brain Region:Thalamus | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months (3)
Brain Region:Thalamus | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months (3)
Brain Region:Thalamus | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months (3)
Brain Region:Thalamus | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months (3)
Brain Region:Thalamus | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months (3)
Brain Region:Thalamus | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months (3)
Brain Region:TOTAL | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months (3)
Brain Region:TOTAL | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months (3)
Brain Region:TOTAL | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months (3)
Brain Region:TOTAL | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months (3)
Brain Region:TOTAL | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months (3)
Brain Region:TOTAL | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months (3)
P-value cutoff:
None
0.1
0.02
0.05
0.01
0.005
0.002
0.001
0.0005
0.0002
Fold-change cutoff:
None
1.1
1.2
1.25
1.33
1.5
2
3
4
5
Sample normalization:
None
Mean
Sum
Group by metabolite classification:
Sub class
Main class
Use:
Submitted metabolite names
RefMet names
Maximum # of (most significant) metabolites per class to use in pvalue group calculation:
1
3
5
10
20
All
Analysis:
None (Direct infusion) NEGATIVE ION MODE
Combine data for all analyses?:
Metabolomics Workbench
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