| Analysis | Metabolite Name | Measured Value | Units | Genotype | Treatment | Metabolite | Tissue |
|---|---|---|---|---|---|---|---|
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.039 | mg/mL | F344 Pirc | 200 ppm Naproxen | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.042 | mg/mL | F344 Pirc | AIN-93G (control) | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.047 | mg/mL | F344 Pirc | EPA-FFA (2%) + 200 ppm Naproxen | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.049 | mg/mL | F344 Pirc | EPA-FFA (2% EPA) | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.051 | mg/mL | F344 Pirc | EPA-FFA (2% EPA) | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.052 | mg/mL | F344 Pirc | EPA-FFA (2% EPA) | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.052 | mg/mL | F344 Pirc | HD TP-252 (3% EPA) + 200 ppm Naproxen | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.055 | mg/mL | F344 Pirc | EPA-FFA (2% EPA) | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.058 | mg/mL | F344 Pirc | EPA-FFA (2% EPA) | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.060 | mg/mL | F344 Pirc | EPA-FFA (2%) + 200 ppm Naproxen | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.061 | mg/mL | F344 Pirc | 200 ppm Naproxen | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.061 | mg/mL | F344 Pirc | EPA-FFA (2%) + 200 ppm Naproxen | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.064 | mg/mL | F344 Pirc | EPA-FFA (2%) + 200 ppm Naproxen | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.064 | mg/mL | F344 Pirc | LD TP-252 (1.5% EPA) + 200 ppm Naproxen | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.066 | mg/mL | F344 Pirc | HD TP-252 (3% EPA) + 200 ppm Naproxen | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.067 | mg/mL | F344 Pirc | HD TP-252 (3% EPA) | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.068 | mg/mL | F344 Pirc | HD TP-252 (3% EPA) | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.068 | mg/mL | F344 Pirc | LD TP-252 (1.5% EPA) | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.069 | mg/mL | F344 Pirc | 200 ppm Naproxen | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.069 | mg/mL | F344 Pirc | LD TP-252 (1.5% EPA) + 200 ppm Naproxen | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.070 | mg/mL | F344 Pirc | LD TP-252 (1.5% EPA) + 200 ppm Naproxen | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.071 | mg/mL | F344 Pirc | EPA-FFA (2%) + 200 ppm Naproxen | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.071 | mg/mL | F344 Pirc | LD TP-252 (1.5% EPA) + 200 ppm Naproxen | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.072 | mg/mL | F344 Pirc | AIN-93G (control) | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.073 | mg/mL | F344 Pirc | LD TP-252 (1.5% EPA) | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.075 | mg/mL | F344 Pirc | LD TP-252 (1.5% EPA) + 200 ppm Naproxen | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.076 | mg/mL | F344 Pirc | AIN-93G (control) | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.076 | mg/mL | F344 Pirc | EPA-FFA (2% EPA) | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.076 | mg/mL | F344 Pirc | LD TP-252 (1.5% EPA) + 200 ppm Naproxen | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.077 | mg/mL | F344 Pirc | LD TP-252 (1.5% EPA) | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.078 | mg/mL | F344 Pirc | 200 ppm Naproxen | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.078 | mg/mL | F344 Pirc | AIN-93G (control) | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.079 | mg/mL | F344 Pirc | EPA-FFA (2%) + 200 ppm Naproxen | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.080 | mg/mL | F344 Pirc | LD TP-252 (1.5% EPA) | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.084 | mg/mL | F344 Pirc | AIN-93G (control) | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.084 | mg/mL | F344 Pirc | HD TP-252 (3% EPA) + 200 ppm Naproxen | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.085 | mg/mL | F344 Pirc | 200 ppm Naproxen | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.085 | mg/mL | F344 Pirc | HD TP-252 (3% EPA) | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.086 | mg/mL | F344 Pirc | 200 ppm Naproxen | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.087 | mg/mL | F344 Pirc | HD TP-252 (3% EPA) | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.095 | mg/mL | F344 Pirc | HD TP-252 (3% EPA) + 200 ppm Naproxen | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.099 | mg/mL | F344 Pirc | HD TP-252 (3% EPA) + 200 ppm Naproxen | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.100 | mg/mL | F344 Pirc | AIN-93G (control) | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.102 | mg/mL | F344 Pirc | LD TP-252 (1.5% EPA) | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.109 | mg/mL | F344 Pirc | LD TP-252 (1.5% EPA) | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.130 | mg/mL | F344 Pirc | EPA-FFA (2% EPA) | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.130 | mg/mL | F344 Pirc | HD TP-252 (3% EPA) + 200 ppm Naproxen | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.134 | mg/mL | F344 Pirc | HD TP-252 (3% EPA) | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.135 | mg/mL | F344 Pirc | HD TP-252 (3% EPA) + 200 ppm Naproxen | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 0.155 | mg/mL | F344 Pirc | AIN-93G (control) | Fatty Acid | Plasma |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 1.293 | mg/g tissue | F344 Pirc | HD TP-252 (3% EPA) | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 1.422 | mg/g tissue | F344 Pirc | EPA-FFA (2% EPA) | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 1.487 | mg/g tissue | F344 Pirc | 200 ppm Naproxen | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 1.615 | mg/g tissue | F344 Pirc | 200 ppm Naproxen | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 1.664 | mg/g tissue | F344 Pirc | EPA-FFA (2%) + 200 ppm Naproxen | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 1.747 | mg/g tissue | F344 Pirc | HD TP-252 (3% EPA) | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 1.839 | mg/g tissue | F344 Pirc | HD TP-252 (3% EPA) | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 1.842 | mg/g tissue | F344 Pirc | EPA-FFA (2% EPA) | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 1.861 | mg/g tissue | F344 Pirc | EPA-FFA (2% EPA) | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 1.901 | mg/g tissue | F344 Pirc | EPA-FFA (2%) + 200 ppm Naproxen | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 1.904 | mg/g tissue | F344 Pirc | LD TP-252 (1.5% EPA) | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 1.922 | mg/g tissue | F344 Pirc | EPA-FFA (2%) + 200 ppm Naproxen | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 2.008 | mg/g tissue | F344 Pirc | 200 ppm Naproxen | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 2.025 | mg/g tissue | F344 Pirc | 200 ppm Naproxen | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 2.174 | mg/g tissue | F344 Pirc | 200 ppm Naproxen | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 2.207 | mg/g tissue | F344 Pirc | EPA-FFA (2%) + 200 ppm Naproxen | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 2.223 | mg/g tissue | F344 Pirc | LD TP-252 (1.5% EPA) | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 2.272 | mg/g tissue | F344 Pirc | LD TP-252 (1.5% EPA) + 200 ppm Naproxen | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 2.280 | mg/g tissue | F344 Pirc | EPA-FFA (2% EPA) | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 2.334 | mg/g tissue | F344 Pirc | LD TP-252 (1.5% EPA) | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 2.348 | mg/g tissue | F344 Pirc | HD TP-252 (3% EPA) | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 2.378 | mg/g tissue | F344 Pirc | AIN-93G (control) | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 2.393 | mg/g tissue | F344 Pirc | EPA-FFA (2%) + 200 ppm Naproxen | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 2.492 | mg/g tissue | F344 Pirc | LD TP-252 (1.5% EPA) + 200 ppm Naproxen | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 2.576 | mg/g tissue | F344 Pirc | HD TP-252 (3% EPA) + 200 ppm Naproxen | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 2.659 | mg/g tissue | F344 Pirc | EPA-FFA (2%) + 200 ppm Naproxen | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 2.669 | mg/g tissue | F344 Pirc | LD TP-252 (1.5% EPA) + 200 ppm Naproxen | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 2.694 | mg/g tissue | F344 Pirc | LD TP-252 (1.5% EPA) + 200 ppm Naproxen | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 2.768 | mg/g tissue | F344 Pirc | HD TP-252 (3% EPA) + 200 ppm Naproxen | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 2.776 | mg/g tissue | F344 Pirc | EPA-FFA (2% EPA) | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 2.777 | mg/g tissue | F344 Pirc | LD TP-252 (1.5% EPA) | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 2.881 | mg/g tissue | F344 Pirc | EPA-FFA (2% EPA) | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 2.922 | mg/g tissue | F344 Pirc | EPA-FFA (2% EPA) | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 3.040 | mg/g tissue | F344 Pirc | EPA-FFA (2%) + 200 ppm Naproxen | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 3.054 | mg/g tissue | F344 Pirc | AIN-93G (control) | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 3.097 | mg/g tissue | F344 Pirc | LD TP-252 (1.5% EPA) + 200 ppm Naproxen | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 3.159 | mg/g tissue | F344 Pirc | 200 ppm Naproxen | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 3.216 | mg/g tissue | F344 Pirc | AIN-93G (control) | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 3.238 | mg/g tissue | F344 Pirc | HD TP-252 (3% EPA) | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 3.247 | mg/g tissue | F344 Pirc | LD TP-252 (1.5% EPA) + 200 ppm Naproxen | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 3.363 | mg/g tissue | F344 Pirc | AIN-93G (control) | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 3.454 | mg/g tissue | F344 Pirc | HD TP-252 (3% EPA) + 200 ppm Naproxen | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 3.503 | mg/g tissue | F344 Pirc | HD TP-252 (3% EPA) + 200 ppm Naproxen | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 3.533 | mg/g tissue | F344 Pirc | AIN-93G (control) | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 3.827 | mg/g tissue | F344 Pirc | LD TP-252 (1.5% EPA) | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 3.977 | mg/g tissue | F344 Pirc | HD TP-252 (3% EPA) + 200 ppm Naproxen | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 4.021 | mg/g tissue | F344 Pirc | AIN-93G (control) | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 4.047 | mg/g tissue | F344 Pirc | HD TP-252 (3% EPA) + 200 ppm Naproxen | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 4.304 | mg/g tissue | F344 Pirc | HD TP-252 (3% EPA) + 200 ppm Naproxen | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 4.403 | mg/g tissue | F344 Pirc | 200 ppm Naproxen | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 4.440 | mg/g tissue | F344 Pirc | LD TP-252 (1.5% EPA) + 200 ppm Naproxen | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 4.937 | mg/g tissue | F344 Pirc | LD TP-252 (1.5% EPA) | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 5.089 | mg/g tissue | F344 Pirc | AIN-93G (control) | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 5.209 | mg/g tissue | F344 Pirc | HD TP-252 (3% EPA) | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 7.550 | mg/g tissue | F344 Pirc | HD TP-252 (3% EPA) | Fatty Acid | Tumor-adjacent normal colon |
| None (Direct infusion) NEGATIVE ION MODE | Arachidic acid | 9.389 | mg/g tissue | F344 Pirc | LD TP-252 (1.5% EPA) | Fatty Acid | Tumor-adjacent normal colon |
- UCSD Metabolomics Workbench, a resource sponsored by the Common Fund of the National Institutes of Health
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