| Analysis | Metabolite Name | Measured Value | Units | Group | APOE genotype | Treatment |
|---|---|---|---|---|---|---|
| GC POSITIVE ION MODE | Pyruvic acid | 27.51108433 | Fractional Enrichment (adjusted for natural abundance) | E3_proinflammatory | E3/E3 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid | 27.86065381 | Fractional Enrichment (adjusted for natural abundance) | E3_control | E3/E3 | Control |
| GC POSITIVE ION MODE | Pyruvic acid | 28.72169818 | Fractional Enrichment (adjusted for natural abundance) | E4_proinflammatory | E4/E4 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid | 30.73494682 | Fractional Enrichment (adjusted for natural abundance) | E4_control | E4/E4 | Control |
| GC POSITIVE ION MODE | Pyruvic acid | 33.56302892 | Fractional Enrichment (adjusted for natural abundance) | E4_proinflammatory | E4/E4 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid | 35.79953096 | Fractional Enrichment (adjusted for natural abundance) | E4_control | E4/E4 | Control |
| GC POSITIVE ION MODE | Pyruvic acid | 36.54578033 | Fractional Enrichment (adjusted for natural abundance) | E4_proinflammatory | E4/E4 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid | 36.8315281 | Fractional Enrichment (adjusted for natural abundance) | E4_control | E4/E4 | Control |
| GC POSITIVE ION MODE | Pyruvic acid | 37.13190722 | Fractional Enrichment (adjusted for natural abundance) | E3_control | E3/E3 | Control |
| GC POSITIVE ION MODE | Pyruvic acid | 39.58435399 | Fractional Enrichment (adjusted for natural abundance) | E3_proinflammatory | E3/E3 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid | 43.70983361 | Fractional Enrichment (adjusted for natural abundance) | E3_control | E3/E3 | Control |
| GC POSITIVE ION MODE | Pyruvic acid | 44.44812968 | Fractional Enrichment (adjusted for natural abundance) | E3_proinflammatory | E3/E3 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid | 44.56509299 | Fractional Enrichment (adjusted for natural abundance) | E3_control | E3/E3 | Control |
| GC POSITIVE ION MODE | Pyruvic acid | 46.60241407 | Fractional Enrichment (adjusted for natural abundance) | E3_control | E3/E3 | Control |
| GC POSITIVE ION MODE | Pyruvic acid | 49.60560957 | Fractional Enrichment (adjusted for natural abundance) | E3_proinflammatory | E3/E3 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid | 50.11426557 | Fractional Enrichment (adjusted for natural abundance) | E4_proinflammatory | E4/E4 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid | 52.61921617 | Fractional Enrichment (adjusted for natural abundance) | E3_proinflammatory | E3/E3 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid | 52.65937904 | Fractional Enrichment (adjusted for natural abundance) | E3_proinflammatory | E3/E3 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid | 54.82112392 | Fractional Enrichment (adjusted for natural abundance) | E4_control | E4/E4 | Control |
| GC POSITIVE ION MODE | Pyruvic acid | 55.66063718 | Fractional Enrichment (adjusted for natural abundance) | E4_proinflammatory | E4/E4 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid | 59.89044304 | Fractional Enrichment (adjusted for natural abundance) | E4_proinflammatory | E4/E4 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid | 60.86801665 | Fractional Enrichment (adjusted for natural abundance) | E4_control | E4/E4 | Control |
| GC POSITIVE ION MODE | Pyruvic acid | 61.33121599 | Fractional Enrichment (adjusted for natural abundance) | E4_control | E4/E4 | Control |
| GC POSITIVE ION MODE | Pyruvic acid | 61.3855051 | Fractional Enrichment (adjusted for natural abundance) | E4_control | E4/E4 | Control |
| GC POSITIVE ION MODE | Pyruvic acid | 62.48673442 | Fractional Enrichment (adjusted for natural abundance) | E3_proinflammatory | E3/E3 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid | 65.11339702 | Fractional Enrichment (adjusted for natural abundance) | E4_proinflammatory | E4/E4 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid | 67.31029927 | Fractional Enrichment (adjusted for natural abundance) | E3_control | E3/E3 | Control |
| GC POSITIVE ION MODE | Pyruvic acid | 73.7033551 | Fractional Enrichment (adjusted for natural abundance) | E3_control | E3/E3 | Control |
| GC POSITIVE ION MODE | Pyruvic acid | 79.12872878 | Fractional Enrichment (adjusted for natural abundance) | E3_proinflammatory | E3/E3 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid | 85.15340672 | Fractional Enrichment (adjusted for natural abundance) | E3_control | E3/E3 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_1 | -6.122857151 | Fractional Enrichment (adjusted for natural abundance) | E4_control | E4/E4 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_1 | -5.59916197 | Fractional Enrichment (adjusted for natural abundance) | E4_proinflammatory | E4/E4 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_1 | -5.514656465 | Fractional Enrichment (adjusted for natural abundance) | E4_control | E4/E4 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_1 | -5.041396782 | Fractional Enrichment (adjusted for natural abundance) | E4_proinflammatory | E4/E4 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_1 | -4.989773155 | Fractional Enrichment (adjusted for natural abundance) | E3_proinflammatory | E3/E3 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_1 | -4.687458911 | Fractional Enrichment (adjusted for natural abundance) | E3_control | E3/E3 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_1 | -4.482832618 | Fractional Enrichment (adjusted for natural abundance) | E3_control | E3/E3 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_1 | -4.475415015 | Fractional Enrichment (adjusted for natural abundance) | E3_control | E3/E3 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_1 | -4.397100684 | Fractional Enrichment (adjusted for natural abundance) | E3_control | E3/E3 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_1 | -4.064479709 | Fractional Enrichment (adjusted for natural abundance) | E4_proinflammatory | E4/E4 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_1 | -3.982049423 | Fractional Enrichment (adjusted for natural abundance) | E3_proinflammatory | E3/E3 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_1 | -3.735056162 | Fractional Enrichment (adjusted for natural abundance) | E3_control | E3/E3 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_1 | -3.704935679 | Fractional Enrichment (adjusted for natural abundance) | E4_control | E4/E4 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_1 | -3.688409145 | Fractional Enrichment (adjusted for natural abundance) | E3_control | E3/E3 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_1 | -3.601132515 | Fractional Enrichment (adjusted for natural abundance) | E4_control | E4/E4 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_1 | -3.585328885 | Fractional Enrichment (adjusted for natural abundance) | E4_control | E4/E4 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_1 | -3.358709209 | Fractional Enrichment (adjusted for natural abundance) | E3_control | E3/E3 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_1 | -3.091784008 | Fractional Enrichment (adjusted for natural abundance) | E4_control | E4/E4 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_1 | -2.957435275 | Fractional Enrichment (adjusted for natural abundance) | E3_proinflammatory | E3/E3 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_1 | -2.889052794 | Fractional Enrichment (adjusted for natural abundance) | E4_proinflammatory | E4/E4 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_1 | -2.802629989 | Fractional Enrichment (adjusted for natural abundance) | E3_control | E3/E3 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_1 | -2.767328851 | Fractional Enrichment (adjusted for natural abundance) | E3_proinflammatory | E3/E3 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_1 | -2.570921485 | Fractional Enrichment (adjusted for natural abundance) | E3_proinflammatory | E3/E3 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_1 | -2.25206784 | Fractional Enrichment (adjusted for natural abundance) | E3_proinflammatory | E3/E3 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_1 | -1.887401392 | Fractional Enrichment (adjusted for natural abundance) | E3_proinflammatory | E3/E3 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_1 | -1.373230413 | Fractional Enrichment (adjusted for natural abundance) | E4_control | E4/E4 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_1 | -1.310175914 | Fractional Enrichment (adjusted for natural abundance) | E3_proinflammatory | E3/E3 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_1 | -1.071776551 | Fractional Enrichment (adjusted for natural abundance) | E4_proinflammatory | E4/E4 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_1 | -0.609209819 | Fractional Enrichment (adjusted for natural abundance) | E4_proinflammatory | E4/E4 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_1 | 0.391565915 | Fractional Enrichment (adjusted for natural abundance) | E4_proinflammatory | E4/E4 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_2 | -3.304188122 | Fractional Enrichment (adjusted for natural abundance) | E3_control | E3/E3 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_2 | -3.117854401 | Fractional Enrichment (adjusted for natural abundance) | E3_proinflammatory | E3/E3 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_2 | -2.849762035 | Fractional Enrichment (adjusted for natural abundance) | E4_proinflammatory | E4/E4 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_2 | -2.176123653 | Fractional Enrichment (adjusted for natural abundance) | E4_proinflammatory | E4/E4 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_2 | -2.014175819 | Fractional Enrichment (adjusted for natural abundance) | E3_proinflammatory | E3/E3 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_2 | -2.011271449 | Fractional Enrichment (adjusted for natural abundance) | E4_control | E4/E4 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_2 | -1.811508039 | Fractional Enrichment (adjusted for natural abundance) | E4_control | E4/E4 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_2 | -1.655871291 | Fractional Enrichment (adjusted for natural abundance) | E4_proinflammatory | E4/E4 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_2 | -1.638871286 | Fractional Enrichment (adjusted for natural abundance) | E3_proinflammatory | E3/E3 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_2 | -1.53969548 | Fractional Enrichment (adjusted for natural abundance) | E3_control | E3/E3 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_2 | -1.516215732 | Fractional Enrichment (adjusted for natural abundance) | E4_proinflammatory | E4/E4 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_2 | -1.472460658 | Fractional Enrichment (adjusted for natural abundance) | E3_control | E3/E3 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_2 | -1.444375972 | Fractional Enrichment (adjusted for natural abundance) | E3_control | E3/E3 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_2 | -1.340793078 | Fractional Enrichment (adjusted for natural abundance) | E4_proinflammatory | E4/E4 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_2 | -1.308079719 | Fractional Enrichment (adjusted for natural abundance) | E3_proinflammatory | E3/E3 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_2 | -1.216883918 | Fractional Enrichment (adjusted for natural abundance) | E4_control | E4/E4 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_2 | -1.183017325 | Fractional Enrichment (adjusted for natural abundance) | E4_control | E4/E4 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_2 | -1.160930359 | Fractional Enrichment (adjusted for natural abundance) | E3_control | E3/E3 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_2 | -1.015679102 | Fractional Enrichment (adjusted for natural abundance) | E4_control | E4/E4 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_2 | -0.949033035 | Fractional Enrichment (adjusted for natural abundance) | E4_proinflammatory | E4/E4 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_2 | -0.920432651 | Fractional Enrichment (adjusted for natural abundance) | E3_control | E3/E3 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_2 | -0.908925935 | Fractional Enrichment (adjusted for natural abundance) | E3_proinflammatory | E3/E3 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_2 | -0.903553912 | Fractional Enrichment (adjusted for natural abundance) | E3_proinflammatory | E3/E3 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_2 | -0.865213395 | Fractional Enrichment (adjusted for natural abundance) | E3_control | E3/E3 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_2 | -0.60379387 | Fractional Enrichment (adjusted for natural abundance) | E3_proinflammatory | E3/E3 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_2 | -0.404117526 | Fractional Enrichment (adjusted for natural abundance) | E4_control | E4/E4 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_2 | -0.208114677 | Fractional Enrichment (adjusted for natural abundance) | E4_control | E4/E4 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_2 | 0.107118299 | Fractional Enrichment (adjusted for natural abundance) | E3_proinflammatory | E3/E3 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_2 | 1.317814312 | Fractional Enrichment (adjusted for natural abundance) | E3_control | E3/E3 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_2 | 2.469336166 | Fractional Enrichment (adjusted for natural abundance) | E4_proinflammatory | E4/E4 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_3 | 21.83919054 | Fractional Enrichment (adjusted for natural abundance) | E3_control | E3/E3 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_3 | 26.94656089 | Fractional Enrichment (adjusted for natural abundance) | E3_proinflammatory | E3/E3 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_3 | 30.81628447 | Fractional Enrichment (adjusted for natural abundance) | E3_control | E3/E3 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_3 | 37.3447991 | Fractional Enrichment (adjusted for natural abundance) | E4_proinflammatory | E4/E4 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_3 | 38.03032914 | Fractional Enrichment (adjusted for natural abundance) | E3_control | E3/E3 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_3 | 39.65821512 | Fractional Enrichment (adjusted for natural abundance) | E3_proinflammatory | E3/E3 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_3 | 40.19583999 | Fractional Enrichment (adjusted for natural abundance) | E4_control | E4/E4 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_3 | 42.65823042 | Fractional Enrichment (adjusted for natural abundance) | E4_control | E4/E4 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_3 | 46.35016032 | Fractional Enrichment (adjusted for natural abundance) | E4_proinflammatory | E4/E4 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_3 | 47.26611195 | Fractional Enrichment (adjusted for natural abundance) | E4_control | E4/E4 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_3 | 47.46918863 | Fractional Enrichment (adjusted for natural abundance) | E4_proinflammatory | E4/E4 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_3 | 49.29475362 | Fractional Enrichment (adjusted for natural abundance) | E3_proinflammatory | E3/E3 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_3 | 51.92571826 | Fractional Enrichment (adjusted for natural abundance) | E3_proinflammatory | E3/E3 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_3 | 52.50504058 | Fractional Enrichment (adjusted for natural abundance) | E4_control | E4/E4 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_3 | 56.58300251 | Fractional Enrichment (adjusted for natural abundance) | E4_proinflammatory | E4/E4 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_3 | 57.02303487 | Fractional Enrichment (adjusted for natural abundance) | E3_proinflammatory | E3/E3 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_3 | 58.34282562 | Fractional Enrichment (adjusted for natural abundance) | E3_proinflammatory | E3/E3 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_3 | 59.62474032 | Fractional Enrichment (adjusted for natural abundance) | E3_control | E3/E3 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_3 | 61.39020029 | Fractional Enrichment (adjusted for natural abundance) | E3_control | E3/E3 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_3 | 62.13164304 | Fractional Enrichment (adjusted for natural abundance) | E3_control | E3/E3 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_3 | 65.28533463 | Fractional Enrichment (adjusted for natural abundance) | E3_control | E3/E3 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_3 | 65.57964522 | Fractional Enrichment (adjusted for natural abundance) | E4_proinflammatory | E4/E4 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_3 | 65.70577515 | Fractional Enrichment (adjusted for natural abundance) | E3_proinflammatory | E3/E3 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_3 | 68.09029149 | Fractional Enrichment (adjusted for natural abundance) | E4_control | E4/E4 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_3 | 68.84954071 | Fractional Enrichment (adjusted for natural abundance) | E4_proinflammatory | E4/E4 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_3 | 68.98461888 | Fractional Enrichment (adjusted for natural abundance) | E4_control | E4/E4 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_3 | 73.37251629 | Fractional Enrichment (adjusted for natural abundance) | E4_control | E4/E4 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_3 | 75.11638765 | Fractional Enrichment (adjusted for natural abundance) | E4_proinflammatory | E4/E4 | Proinflammatory |
| GC POSITIVE ION MODE | Pyruvic acid_13C_3 | 75.86240883 | Fractional Enrichment (adjusted for natural abundance) | E3_control | E3/E3 | Control |
| GC POSITIVE ION MODE | Pyruvic acid_13C_3 | 76.16517046 | Fractional Enrichment (adjusted for natural abundance) | E3_proinflammatory | E3/E3 | Proinflammatory |
- UCSD Metabolomics Workbench, a resource sponsored by the Common Fund of the National Institutes of Health
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