Analysis Metabolite Name Measured Value Units Tissue Anesthesia / Euthanasia method
ESI negative ion modeLactate8929.882545Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Ketamine
ESI negative ion modeLactate11747.50903Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Ketamine
ESI negative ion modeLactate13987.92874peak area (normalized to tissue mass)Liver Ketamine
ESI negative ion modeLactate14419.2719Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Pentobarbital
ESI negative ion modeLactate14532.76183Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Pentobarbital
ESI negative ion modeLactate15310.11408Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Ketamine
ESI negative ion modeLactate17392.72187Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Ketamine
ESI negative ion modeLactate17471.68173peak area (normalized to tissue mass)Liver Continuous isoflurane
ESI negative ion modeLactate18796.87769Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Ketamine
ESI negative ion modeLactate19093.40736Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Ketamine
ESI negative ion modeLactate20017.9657Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Ketamine
ESI negative ion modeLactate20307.37201Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Continuous isoflurane
ESI negative ion modeLactate20460.08226peak area (normalized to tissue mass)Liver Continuous isoflurane
ESI negative ion modeLactate21320.2656Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Ketamine
ESI negative ion modeLactate24348.61488Peak area (normalized to tissue mass)Epididymal white adipose (fat) Ketamine
ESI negative ion modeLactate25072.03859peak area (normalized to tissue mass)Liver Ketamine
ESI negative ion modeLactate26406.45589Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Continuous isoflurane
ESI negative ion modeLactate26526.26166Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Continuous isoflurane
ESI negative ion modeLactate26922.70318Peak area (normalized to tissue mass)Epididymal white adipose (fat) Ketamine
ESI negative ion modeLactate27174.89708Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Continuous isoflurane
ESI negative ion modeLactate27794.49728peak area (normalized to tissue mass)Liver Ketamine
ESI negative ion modeLactate28411.81177Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Pentobarbital
ESI negative ion modeLactate28578.22733Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Pentobarbital
ESI negative ion modeLactate29554.94828Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Pentobarbital
ESI negative ion modeLactate29673.59426Peak area (normalized to tissue mass)Epididymal white adipose (fat) Ketamine
ESI negative ion modeLactate30411.25334Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Pentobarbital
ESI negative ion modeLactate30437.53414Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Pentobarbital
ESI negative ion modeLactate33135.93945Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Continuous isoflurane
ESI negative ion modeLactate33908.74108peak area (normalized to tissue mass)Liver Pentobarbital
ESI negative ion modeLactate34066.56579Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Continuous isoflurane
ESI negative ion modeLactate34919.82145Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Continuous isoflurane
ESI negative ion modeLactate36568.00001Peak area (normalized to tissue mass)Epididymal white adipose (fat) Pentobarbital
ESI negative ion modeLactate37456.35517peak area (normalized to tissue mass)Liver Pentobarbital
ESI negative ion modeLactate37996.91068Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Continuous isoflurane
ESI negative ion modeLactate38044.2947peak area (normalized to tissue mass)Liver Ketamine
ESI negative ion modeLactate39038.13337Peak area (normalized to tissue mass)Epididymal white adipose (fat) Ketamine
ESI negative ion modeLactate41394.98329Peak area (normalized to tissue mass)Epididymal white adipose (fat) Ketamine
ESI negative ion modeLactate42321.73676peak area (normalized to tissue mass)Liver Pentobarbital
ESI negative ion modeLactate43997.76219peak area (normalized to tissue mass)Liver Ketamine
ESI negative ion modeLactate45202.95403Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Isoflurane overdose
ESI negative ion modeLactate45579.40457peak area (normalized to tissue mass)Liver Pentobarbital
ESI negative ion modeLactate46489.81508Peak area (normalized to tissue mass)Epididymal white adipose (fat) Continuous isoflurane
ESI negative ion modeLactate47474.07347peak area (normalized to tissue mass)Liver Continuous isoflurane
ESI negative ion modeLactate48684.97563peak area (normalized to tissue mass)Liver Continuous isoflurane
ESI negative ion modeLactate49924.39705Peak area (normalized to tissue mass)Epididymal white adipose (fat) Continuous isoflurane
ESI negative ion modeLactate51686.12778peak area (normalized to tissue mass)Liver Continuous isoflurane
ESI negative ion modeLactate51753.67198Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Carbon Dioxide
ESI negative ion modeLactate53306.67816peak area (normalized to tissue mass)Liver Continuous isoflurane
ESI negative ion modeLactate53383.21723peak area (normalized to tissue mass)Liver Pentobarbital
ESI negative ion modeLactate53985.35198Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Pentobarbital
ESI negative ion modeLactate55885.17946Peak area (normalized to tissue mass)Epididymal white adipose (fat) Pentobarbital
ESI negative ion modeLactate57806.46504Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Isoflurane overdose
ESI negative ion modeLactate58624.34621Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Cervical Dislocation
ESI negative ion modeLactate59148.49145Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Carbon Dioxide
ESI negative ion modeLactate59438.76297Peak area (normalized to tissue mass)Epididymal white adipose (fat) Continuous isoflurane
ESI negative ion modeLactate60323.10068Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Isoflurane overdose
ESI negative ion modeLactate61574.28213Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Carbon Dioxide
ESI negative ion modeLactate62161.88714Peak area (normalized to tissue mass)Epididymal white adipose (fat) Ketamine
ESI negative ion modeLactate62768.97038Peak area (normalized to tissue mass)Epididymal white adipose (fat) Isoflurane overdose
ESI negative ion modeLactate64481.40601Peak area (normalized to tissue mass)Epididymal white adipose (fat) Pentobarbital
ESI negative ion modeLactate64698.61007Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Isoflurane overdose
ESI negative ion modeLactate64725.93338Peak area (normalized to tissue mass)Epididymal white adipose (fat) Ketamine
ESI negative ion modeLactate66165.0756Peak area (normalized to tissue mass)Epididymal white adipose (fat) Isoflurane overdose
ESI negative ion modeLactate68759.20262Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Isoflurane overdose
ESI negative ion modeLactate70648.42322Peak area (normalized to tissue mass)Epididymal white adipose (fat) Pentobarbital
ESI negative ion modeLactate70903.16953Peak area (normalized to tissue mass)Epididymal white adipose (fat) Continuous isoflurane
ESI negative ion modeLactate71307.40697Peak area (normalized to tissue mass)Epididymal white adipose (fat) Continuous isoflurane
ESI negative ion modeLactate72173.08707Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Carbon Dioxide
ESI negative ion modeLactate72405.56738Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Isoflurane overdose
ESI negative ion modeLactate72999.21581peak area (normalized to tissue mass)Liver Cervical Dislocation
ESI negative ion modeLactate73276.17486peak area (normalized to tissue mass)Liver Pentobarbital
ESI negative ion modeLactate73391.51071Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Carbon Dioxide
ESI negative ion modeLactate73535.5753Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Carbon Dioxide
ESI negative ion modeLactate74928.02864Peak area (normalized to tissue mass)Epididymal white adipose (fat) Continuous isoflurane
ESI negative ion modeLactate75277.61198Peak area (normalized to tissue mass)Epididymal white adipose (fat) Ketamine
ESI negative ion modeLactate76152.46564peak area (normalized to tissue mass)Liver Pentobarbital
ESI negative ion modeLactate76851.90973Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Carbon Dioxide
ESI negative ion modeLactate78675.00111peak area (normalized to tissue mass)Liver Cervical Dislocation
ESI negative ion modeLactate79315.02731peak area (normalized to tissue mass)Liver Continuous isoflurane
ESI negative ion modeLactate79769.13045Peak area (normalized to tissue mass)Epididymal white adipose (fat) Cervical Dislocation
ESI negative ion modeLactate80157.14938Peak area (normalized to tissue mass)Epididymal white adipose (fat) Isoflurane overdose
ESI negative ion modeLactate81554.60919Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Cervical Dislocation
ESI negative ion modeLactate82503.70644Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Cervical Dislocation
ESI negative ion modeLactate82992.7266peak area (normalized to tissue mass)Liver Ketamine
ESI negative ion modeLactate83155.11101Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Isoflurane overdose
ESI negative ion modeLactate84546.97713Peak area (normalized to tissue mass)Epididymal white adipose (fat) Pentobarbital
ESI negative ion modeLactate84826.12864Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Cervical Dislocation
ESI negative ion modeLactate85878.23464Peak area (normalized to tissue mass)Epididymal white adipose (fat) Carbon Dioxide
ESI negative ion modeLactate86257.02796Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Isoflurane overdose
ESI negative ion modeLactate89035.07374Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Carbon Dioxide
ESI negative ion modeLactate89726.53212Peak area (normalized to tissue mass)Epididymal white adipose (fat) Carbon Dioxide
ESI negative ion modeLactate90395.32486peak area (normalized to tissue mass)Liver Pentobarbital
ESI negative ion modeLactate90828.62094Peak area (normalized to tissue mass)Epididymal white adipose (fat) Pentobarbital
ESI negative ion modeLactate91072.01625Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Carbon Dioxide
ESI negative ion modeLactate92029.85206Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Cervical Dislocation
ESI negative ion modeLactate92886.99093peak area (normalized to tissue mass)Liver Carbon Dioxide
ESI negative ion modeLactate96763.11018Peak area (normalized to tissue mass)Epididymal white adipose (fat) Continuous isoflurane
ESI negative ion modeLactate97358.13475peak area (normalized to tissue mass)Liver Ketamine
ESI negative ion modeLactate99065.96615Peak area (normalized to tissue mass)Epididymal white adipose (fat) Carbon Dioxide
ESI negative ion modeLactate99592.17015Peak area (normalized to tissue mass)Epididymal white adipose (fat) Isoflurane overdose
ESI negative ion modeLactate100444.55Peak area (normalized to tissue mass)Epididymal white adipose (fat) Isoflurane overdose
ESI negative ion modeLactate101217.4167Peak area (normalized to tissue mass)Epididymal white adipose (fat) Continuous isoflurane
ESI negative ion modeLactate101464.7621peak area (normalized to tissue mass)Liver Carbon Dioxide
ESI negative ion modeLactate102294.6249peak area (normalized to tissue mass)Liver Isoflurane overdose
ESI negative ion modeLactate103177.1441Peak area (normalized to tissue mass)Epididymal white adipose (fat) Cervical Dislocation
ESI negative ion modeLactate103546.764peak area (normalized to tissue mass)Liver Isoflurane overdose
ESI negative ion modeLactate104443.4244peak area (normalized to tissue mass)Liver Cervical Dislocation
ESI negative ion modeLactate105243.5179peak area (normalized to tissue mass)Liver Isoflurane overdose
ESI negative ion modeLactate106809.5753Peak area (normalized to tissue mass)Epididymal white adipose (fat) Pentobarbital
ESI negative ion modeLactate106989.9632peak area (normalized to tissue mass)Liver Cervical Dislocation
ESI negative ion modeLactate107061.6465Peak area (normalized to tissue mass)Epididymal white adipose (fat) Carbon Dioxide
ESI negative ion modeLactate108319.7118Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Cervical Dislocation
ESI negative ion modeLactate108495.7424Peak area (normalized to tissue mass)Epididymal white adipose (fat) Cervical Dislocation
ESI negative ion modeLactate109566.6104Peak area (normalized to tissue mass)Epididymal white adipose (fat) Carbon Dioxide
ESI negative ion modeLactate110086.9495Peak area (normalized to tissue mass)Epididymal white adipose (fat) Isoflurane overdose
ESI negative ion modeLactate110326.546Peak area (normalized to tissue mass)Epididymal white adipose (fat) Cervical Dislocation
ESI negative ion modeLactate112088.5165peak area (normalized to tissue mass)Liver Isoflurane overdose
ESI negative ion modeLactate112102.9062Peak area (normalized to tissue mass)Epididymal white adipose (fat) Cervical Dislocation
ESI negative ion modeLactate113370.514Peak area (normalized to tissue mass)Epididymal white adipose (fat) Cervical Dislocation
ESI negative ion modeLactate114773.8164Peak area (normalized to tissue mass)Epididymal white adipose (fat) Carbon Dioxide
ESI negative ion modeLactate115487.1976peak area (normalized to tissue mass)Liver Continuous isoflurane
ESI negative ion modeLactate117809.3302Peak area (normalized to tissue mass)Epididymal white adipose (fat) Cervical Dislocation
ESI negative ion modeLactate121759.0081Peak area (normalized to tissue mass)Epididymal white adipose (fat) Pentobarbital
ESI negative ion modeLactate122189.7457peak area (normalized to tissue mass)Liver Ketamine
ESI negative ion modeLactate123186.4281Peak area (normalized to tissue mass)Epididymal white adipose (fat) Carbon Dioxide
ESI negative ion modeLactate123579.8407Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Cervical Dislocation
ESI negative ion modeLactate128229.7063peak area (normalized to tissue mass)Liver Carbon Dioxide
ESI negative ion modeLactate128832.4354peak area (normalized to tissue mass)Liver Cervical Dislocation
ESI negative ion modeLactate129035.9317peak area (normalized to tissue mass)Liver Isoflurane overdose
ESI negative ion modeLactate131903.2172peak area (normalized to tissue mass)Liver Carbon Dioxide
ESI negative ion modeLactate132517.2795peak area (normalized to tissue mass)Liver Isoflurane overdose
ESI negative ion modeLactate132761.9317Peak area (normalized to tissue mass)Epididymal white adipose (fat) Carbon Dioxide
ESI negative ion modeLactate133390.7525peak area (normalized to tissue mass)Liver Cervical Dislocation
ESI negative ion modeLactate136593.2488Peak area (normalized to tissue mass)Epididymal white adipose (fat) Carbon Dioxide
ESI negative ion modeLactate140398.3193peak area (normalized to tissue mass)Liver Carbon Dioxide
ESI negative ion modeLactate142924.9066Peak area (normalized to tissue mass)Epididymal white adipose (fat) Isoflurane overdose
ESI negative ion modeLactate149805.2201peak area (normalized to tissue mass)Liver Cervical Dislocation
ESI negative ion modeLactate157018.2433Peak area (normalized to tissue mass)Epididymal white adipose (fat) Isoflurane overdose
ESI negative ion modeLactate161937.6355peak area (normalized to tissue mass)Liver Isoflurane overdose
ESI negative ion modeLactate168893.7587Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Cervical Dislocation
ESI negative ion modeLactate175203.2682peak area (normalized to tissue mass)Liver Carbon Dioxide
ESI negative ion modeLactate191781.862peak area (normalized to tissue mass)Liver Carbon Dioxide
ESI negative ion modeLactate193869.624Peak area (normalized to tissue mass)Epididymal white adipose (fat) Cervical Dislocation
ESI negative ion modeLactate209518.0619peak area (normalized to tissue mass)Liver Cervical Dislocation
ESI negative ion modeLactate230056.8208peak area (normalized to tissue mass)Liver Isoflurane overdose
ESI negative ion modeLactate237512.9193peak area (normalized to tissue mass)Liver Carbon Dioxide
ESI negative ion modeLactate275755.8372peak area (normalized to tissue mass)Liver Carbon Dioxide
ESI negative ion modeLactate400947.218Peak area (normalized to tissue mass)Heart Ketamine
ESI negative ion modeLactate420014.8039Peak area (normalized to tissue mass)Heart Pentobarbital
ESI negative ion modeLactate445711.3715Peak area (normalized to tissue mass)Heart Ketamine
ESI negative ion modeLactate527692.4296Peak area (normalized to tissue mass)Heart Continuous isoflurane
ESI negative ion modeLactate553777.1953Peak area (normalized to tissue mass)Heart Pentobarbital
ESI negative ion modeLactate664908.2503Peak area (normalized to tissue mass)Heart Pentobarbital
ESI negative ion modeLactate672842.766Peak area (normalized to tissue mass)Heart Ketamine
ESI negative ion modeLactate735055.9634Peak area (normalized to tissue mass)Heart Continuous isoflurane
ESI negative ion modeLactate749770.8517Peak area (normalized to tissue mass)Heart Continuous isoflurane
ESI negative ion modeLactate762052.1781Peak area (normalized to tissue mass)Heart Pentobarbital
ESI negative ion modeLactate1141020.889Peak area (normalized to tissue mass)Heart Continuous isoflurane
ESI negative ion modeLactate1187066.993Peak area (normalized to tissue mass)Heart Continuous isoflurane
ESI negative ion modeLactate1206298.329Peak area (normalized to tissue mass)Heart Pentobarbital
ESI negative ion modeLactate1308675.074Peak area (normalized to tissue mass)Heart Pentobarbital
ESI negative ion modeLactate1336500.651Peak area (normalized to tissue mass)Heart Ketamine
ESI negative ion modeLactate1406914.553Peak area (normalized to tissue mass)Heart Continuous isoflurane
ESI negative ion modeLactate1412878.991Peak area (normalized to tissue mass)Heart Continuous isoflurane
ESI negative ion modeLactate1417773.571Peak area (normalized to tissue mass)Heart Pentobarbital
ESI negative ion modeLactate1434771.154Peak area (normalized to tissue mass)Heart Pentobarbital
ESI negative ion modeLactate1524118.882Peak area (normalized to tissue mass)Heart Continuous isoflurane
ESI negative ion modeLactate2182946.115Peak area (normalized to tissue mass)Heart Ketamine
ESI negative ion modeLactate2242810.681Peak areaSerum Ketamine
ESI negative ion modeLactate2268652.61Peak area (normalized to tissue mass)Heart Ketamine
ESI negative ion modeLactate2906964.976Peak area (normalized to tissue mass)Heart Ketamine
ESI negative ion modeLactate3105704.087Peak areaSerum Ketamine
ESI negative ion modeLactate3576069.179Peak area (normalized to tissue mass)Heart Isoflurane overdose
ESI negative ion modeLactate3888512.499Peak area (normalized to tissue mass)Heart Isoflurane overdose
ESI negative ion modeLactate3991233.66Peak area (normalized to tissue mass)Heart Carbon Dioxide
ESI negative ion modeLactate4011517.465Peak area (normalized to tissue mass)Heart Cervical Dislocation
ESI negative ion modeLactate4054065.387Peak area (normalized to tissue mass)Heart Ketamine
ESI negative ion modeLactate4173999.352Peak area (normalized to tissue mass)Heart Carbon Dioxide
ESI negative ion modeLactate4419470.292Peak area (normalized to tissue mass)Heart Carbon Dioxide
ESI negative ion modeLactate4458078.487Peak area (normalized to tissue mass)Heart Carbon Dioxide
ESI negative ion modeLactate4549445.765Peak area (normalized to tissue mass)Heart Isoflurane overdose
ESI negative ion modeLactate4883290.032Peak area (normalized to tissue mass)Heart Isoflurane overdose
ESI negative ion modeLactate4958236.397Peak area (normalized to tissue mass)Heart Cervical Dislocation
ESI negative ion modeLactate4969230.741Peak area (normalized to tissue mass)Heart Cervical Dislocation
ESI negative ion modeLactate4973875.957Peak area (normalized to tissue mass)Heart Isoflurane overdose
ESI negative ion modeLactate5006226.304Peak area (normalized to tissue mass)Heart Isoflurane overdose
ESI negative ion modeLactate5024695.304Peak area (normalized to tissue mass)Heart Carbon Dioxide
ESI negative ion modeLactate5178741.02Peak area (normalized to tissue mass)Heart Carbon Dioxide
ESI negative ion modeLactate5195330.253Peak area (normalized to tissue mass)Heart Cervical Dislocation
ESI negative ion modeLactate5195831.24Peak area (normalized to tissue mass)Heart Carbon Dioxide
ESI negative ion modeLactate5219764.286Peak area (normalized to tissue mass)Heart Isoflurane overdose
ESI negative ion modeLactate5325265.592Peak area (normalized to tissue mass)Heart Cervical Dislocation
ESI negative ion modeLactate5909943.055Peak area (normalized to tissue mass)Heart Carbon Dioxide
ESI negative ion modeLactate6210566.765Peak area (normalized to tissue mass)Heart Carbon Dioxide
ESI negative ion modeLactate6348333.458Peak areaSerum Ketamine
ESI negative ion modeLactate6398413.865Peak area (normalized to tissue mass)Heart Cervical Dislocation
ESI negative ion modeLactate6403423.613Peak areaSerum Ketamine
ESI negative ion modeLactate6893085.827Peak area (normalized to tissue mass)Heart Isoflurane overdose
ESI negative ion modeLactate6967479.954Peak areaSerum Ketamine
ESI negative ion modeLactate7719471.047Peak area (normalized to tissue mass)Heart Cervical Dislocation

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