Analysis Metabolite Name Measured Value Units Tissue Anesthesia / Euthanasia method
ESI negative ion modeXanthine99.64172332Peak area (normalized to tissue mass)Epididymal white adipose (fat) Pentobarbital
ESI negative ion modeXanthine485.1272821Peak area (normalized to tissue mass)Epididymal white adipose (fat) Ketamine
ESI negative ion modeXanthine565.2689278Peak area (normalized to tissue mass)Epididymal white adipose (fat) Pentobarbital
ESI negative ion modeXanthine647.4211819Peak area (normalized to tissue mass)Epididymal white adipose (fat) Pentobarbital
ESI negative ion modeXanthine843.8403685Peak areaSerum Pentobarbital
ESI negative ion modeXanthine913.9959379Peak area (normalized to tissue mass)Epididymal white adipose (fat) Ketamine
ESI negative ion modeXanthine962.8445059Peak areaSerum Ketamine
ESI negative ion modeXanthine1006.086568Peak area (normalized to tissue mass)Epididymal white adipose (fat) Ketamine
ESI negative ion modeXanthine1030.354524Peak area (normalized to tissue mass)Epididymal white adipose (fat) Cervical Dislocation
ESI negative ion modeXanthine1053.568499Peak area (normalized to tissue mass)Epididymal white adipose (fat) Pentobarbital
ESI negative ion modeXanthine1209.932222Peak area (normalized to tissue mass)Epididymal white adipose (fat) Ketamine
ESI negative ion modeXanthine1262.58743Peak area (normalized to tissue mass)Epididymal white adipose (fat) Pentobarbital
ESI negative ion modeXanthine1282.449409Peak area (normalized to tissue mass)Epididymal white adipose (fat) Continuous isoflurane
ESI negative ion modeXanthine1372.413397Peak area (normalized to tissue mass)Epididymal white adipose (fat) Isoflurane overdose
ESI negative ion modeXanthine1388.240678Peak area (normalized to tissue mass)Epididymal white adipose (fat) Continuous isoflurane
ESI negative ion modeXanthine1414.947771Peak area (normalized to tissue mass)Epididymal white adipose (fat) Pentobarbital
ESI negative ion modeXanthine1439.270306Peak area (normalized to tissue mass)Epididymal white adipose (fat) Isoflurane overdose
ESI negative ion modeXanthine1508.43172Peak areaSerum Continuous isoflurane
ESI negative ion modeXanthine1684.014819Peak area (normalized to tissue mass)Epididymal white adipose (fat) Ketamine
ESI negative ion modeXanthine1786.695572Peak area (normalized to tissue mass)Epididymal white adipose (fat) Isoflurane overdose
ESI negative ion modeXanthine1811.133082Peak areaSerum Continuous isoflurane
ESI negative ion modeXanthine1812.067402Peak areaSerum Ketamine
ESI negative ion modeXanthine1907.2666Peak area (normalized to tissue mass)Epididymal white adipose (fat) Pentobarbital
ESI negative ion modeXanthine1984.919131Peak area (normalized to tissue mass)Epididymal white adipose (fat) Cervical Dislocation
ESI negative ion modeXanthine2027.674469Peak area (normalized to tissue mass)Epididymal white adipose (fat) Cervical Dislocation
ESI negative ion modeXanthine2093.03966Peak areaSerum Ketamine
ESI negative ion modeXanthine2148.644185Peak area (normalized to tissue mass)Epididymal white adipose (fat) Cervical Dislocation
ESI negative ion modeXanthine2218.408096Peak area (normalized to tissue mass)Epididymal white adipose (fat) Isoflurane overdose
ESI negative ion modeXanthine2293.955671Peak area (normalized to tissue mass)Epididymal white adipose (fat) Pentobarbital
ESI negative ion modeXanthine2304.914351Peak area (normalized to tissue mass)Epididymal white adipose (fat) Carbon Dioxide
ESI negative ion modeXanthine2414.712591Peak area (normalized to tissue mass)Epididymal white adipose (fat) Cervical Dislocation
ESI negative ion modeXanthine2477.949185Peak areaSerum Ketamine
ESI negative ion modeXanthine2500.615459Peak area (normalized to tissue mass)Epididymal white adipose (fat) Ketamine
ESI negative ion modeXanthine2566.570897Peak area (normalized to tissue mass)Epididymal white adipose (fat) Continuous isoflurane
ESI negative ion modeXanthine2634.323923Peak area (normalized to tissue mass)Epididymal white adipose (fat) Carbon Dioxide
ESI negative ion modeXanthine2701.444618Peak area (normalized to tissue mass)Epididymal white adipose (fat) Isoflurane overdose
ESI negative ion modeXanthine2724.976594Peak areaSerum Pentobarbital
ESI negative ion modeXanthine2786.423275Peak areaSerum Continuous isoflurane
ESI negative ion modeXanthine2847.121657Peak area (normalized to tissue mass)Epididymal white adipose (fat) Continuous isoflurane
ESI negative ion modeXanthine2868.127228Peak area (normalized to tissue mass)Epididymal white adipose (fat) Ketamine
ESI negative ion modeXanthine3027.043967Peak areaSerum Continuous isoflurane
ESI negative ion modeXanthine3060.022927Peak area (normalized to tissue mass)Epididymal white adipose (fat) Carbon Dioxide
ESI negative ion modeXanthine3243.562287Peak areaSerum Pentobarbital
ESI negative ion modeXanthine3250.612843Peak areaSerum Pentobarbital
ESI negative ion modeXanthine3286.217227Peak area (normalized to tissue mass)Epididymal white adipose (fat) Cervical Dislocation
ESI negative ion modeXanthine3324.144111Peak area (normalized to tissue mass)Epididymal white adipose (fat) Carbon Dioxide
ESI negative ion modeXanthine3593.641417Peak area (normalized to tissue mass)Epididymal white adipose (fat) Carbon Dioxide
ESI negative ion modeXanthine3751.388297Peak areaSerum Continuous isoflurane
ESI negative ion modeXanthine3836.683308Peak areaSerum Ketamine
ESI negative ion modeXanthine4016.583569Peak area (normalized to tissue mass)Epididymal white adipose (fat) Carbon Dioxide
ESI negative ion modeXanthine4651.978736Peak area (normalized to tissue mass)Epididymal white adipose (fat) Isoflurane overdose
ESI negative ion modeXanthine4797.745238Peak area (normalized to tissue mass)Epididymal white adipose (fat) Continuous isoflurane
ESI negative ion modeXanthine4883.133089Peak area (normalized to tissue mass)Epididymal white adipose (fat) Cervical Dislocation
ESI negative ion modeXanthine4980.412644Peak area (normalized to tissue mass)Epididymal white adipose (fat) Continuous isoflurane
ESI negative ion modeXanthine4986.407619Peak areaSerum Pentobarbital
ESI negative ion modeXanthine5027.136155Peak area (normalized to tissue mass)Epididymal white adipose (fat) Carbon Dioxide
ESI negative ion modeXanthine5144.979369Peak areaSerum Continuous isoflurane
ESI negative ion modeXanthine5683.473318peak area (normalized to tissue mass)Liver Pentobarbital
ESI negative ion modeXanthine5839.03077Peak area (normalized to tissue mass)Epididymal white adipose (fat) Carbon Dioxide
ESI negative ion modeXanthine5905.619373Peak area (normalized to tissue mass)Epididymal white adipose (fat) Continuous isoflurane
ESI negative ion modeXanthine6706.280461Peak area (normalized to tissue mass)Heart Pentobarbital
ESI negative ion modeXanthine6836.300099Peak area (normalized to tissue mass)Epididymal white adipose (fat) Cervical Dislocation
ESI negative ion modeXanthine6862.212503Peak areaSerum Ketamine
ESI negative ion modeXanthine7090.869587Peak area (normalized to tissue mass)Epididymal white adipose (fat) Carbon Dioxide
ESI negative ion modeXanthine7487.166673Peak area (normalized to tissue mass)Heart Continuous isoflurane
ESI negative ion modeXanthine7577.717323Peak area (normalized to tissue mass)Heart Pentobarbital
ESI negative ion modeXanthine7675.816759Peak area (normalized to tissue mass)Epididymal white adipose (fat) Continuous isoflurane
ESI negative ion modeXanthine8041.073888Peak areaSerum Pentobarbital
ESI negative ion modeXanthine8113.609626Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Continuous isoflurane
ESI negative ion modeXanthine8119.72826Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Ketamine
ESI negative ion modeXanthine8356.690454Peak area (normalized to tissue mass)Heart Pentobarbital
ESI negative ion modeXanthine8636.816998Peak area (normalized to tissue mass)Epididymal white adipose (fat) Isoflurane overdose
ESI negative ion modeXanthine8677.794415Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Pentobarbital
ESI negative ion modeXanthine8703.519231Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Ketamine
ESI negative ion modeXanthine8710.835889Peak area (normalized to tissue mass)Epididymal white adipose (fat) Ketamine
ESI negative ion modeXanthine8777.05903Peak area (normalized to tissue mass)Heart Continuous isoflurane
ESI negative ion modeXanthine9486.365232Peak area (normalized to tissue mass)Heart Pentobarbital
ESI negative ion modeXanthine9529.974568Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Continuous isoflurane
ESI negative ion modeXanthine9551.751331Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Continuous isoflurane
ESI negative ion modeXanthine10120.15213Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Ketamine
ESI negative ion modeXanthine10343.35508Peak area (normalized to tissue mass)Heart Ketamine
ESI negative ion modeXanthine10599.69774Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Ketamine
ESI negative ion modeXanthine10915.55929Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Ketamine
ESI negative ion modeXanthine11080.45684Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Isoflurane overdose
ESI negative ion modeXanthine11530.0363Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Cervical Dislocation
ESI negative ion modeXanthine11538.0979Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Isoflurane overdose
ESI negative ion modeXanthine11608.00666Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Continuous isoflurane
ESI negative ion modeXanthine11627.03352Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Pentobarbital
ESI negative ion modeXanthine11700.36824Peak area (normalized to tissue mass)Heart Continuous isoflurane
ESI negative ion modeXanthine11746.37985Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Continuous isoflurane
ESI negative ion modeXanthine11832.70317Peak areaSerum Pentobarbital
ESI negative ion modeXanthine12116.40946Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Continuous isoflurane
ESI negative ion modeXanthine12315.44832Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Continuous isoflurane
ESI negative ion modeXanthine12338.7083Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Pentobarbital
ESI negative ion modeXanthine12373.71856peak area (normalized to tissue mass)Liver Pentobarbital
ESI negative ion modeXanthine12495.00932Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Isoflurane overdose
ESI negative ion modeXanthine12669.94734Peak areaSerum Cervical Dislocation
ESI negative ion modeXanthine12718.96604Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Pentobarbital
ESI negative ion modeXanthine12747.51077Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Pentobarbital
ESI negative ion modeXanthine12779.75541Peak area (normalized to tissue mass)Epididymal white adipose (fat) Isoflurane overdose
ESI negative ion modeXanthine12976.65652Peak area (normalized to tissue mass)Heart Pentobarbital
ESI negative ion modeXanthine13175.96812Peak areaSerum Ketamine
ESI negative ion modeXanthine13530.27857Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Continuous isoflurane
ESI negative ion modeXanthine13791.46799Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Carbon Dioxide
ESI negative ion modeXanthine14185.47139Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Cervical Dislocation
ESI negative ion modeXanthine14224.59091Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Cervical Dislocation
ESI negative ion modeXanthine14299.46028Peak area (normalized to tissue mass)Heart Continuous isoflurane
ESI negative ion modeXanthine14312.29889Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Cervical Dislocation
ESI negative ion modeXanthine14372.94616Peak area (normalized to tissue mass)Heart Continuous isoflurane
ESI negative ion modeXanthine14775.90694Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Pentobarbital
ESI negative ion modeXanthine14977.7493peak area (normalized to tissue mass)Liver Ketamine
ESI negative ion modeXanthine15185.70114Peak area (normalized to tissue mass)Heart Continuous isoflurane
ESI negative ion modeXanthine15739.87945Peak area (normalized to tissue mass)Heart Continuous isoflurane
ESI negative ion modeXanthine16086.01225Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Pentobarbital
ESI negative ion modeXanthine16271.0598peak area (normalized to tissue mass)Liver Pentobarbital
ESI negative ion modeXanthine16985.55145Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Cervical Dislocation
ESI negative ion modeXanthine17010.83236Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Isoflurane overdose
ESI negative ion modeXanthine17351.01232peak area (normalized to tissue mass)Liver Continuous isoflurane
ESI negative ion modeXanthine17420.0432Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Carbon Dioxide
ESI negative ion modeXanthine17441.62389Peak area (normalized to tissue mass)Heart Pentobarbital
ESI negative ion modeXanthine17859.06961Peak area (normalized to tissue mass)Heart Pentobarbital
ESI negative ion modeXanthine18412.62719Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Carbon Dioxide
ESI negative ion modeXanthine18457.35992Peak areaSerum Continuous isoflurane
ESI negative ion modeXanthine18613.81776Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Cervical Dislocation
ESI negative ion modeXanthine18810.78561Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Carbon Dioxide
ESI negative ion modeXanthine18983.36806Peak area (normalized to tissue mass)Heart Ketamine
ESI negative ion modeXanthine19416.74913Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Carbon Dioxide
ESI negative ion modeXanthine19583.19654Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Carbon Dioxide
ESI negative ion modeXanthine20348.16734Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Carbon Dioxide
ESI negative ion modeXanthine21635.8413Peak areaSerum Isoflurane overdose
ESI negative ion modeXanthine21661.36184peak area (normalized to tissue mass)Liver Continuous isoflurane
ESI negative ion modeXanthine22324.56298Peak areaSerum Isoflurane overdose
ESI negative ion modeXanthine22827.27105Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Isoflurane overdose
ESI negative ion modeXanthine22915.82985Peak area (normalized to tissue mass)Heart Ketamine
ESI negative ion modeXanthine22991.32847peak area (normalized to tissue mass)Liver Pentobarbital
ESI negative ion modeXanthine23267.16731Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Cervical Dislocation
ESI negative ion modeXanthine23633.09341Peak area (normalized to tissue mass)Heart Continuous isoflurane
ESI negative ion modeXanthine24982.89117Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Ketamine
ESI negative ion modeXanthine25113.62919Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Cervical Dislocation
ESI negative ion modeXanthine25165.90999peak area (normalized to tissue mass)Liver Pentobarbital
ESI negative ion modeXanthine25181.52794Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Isoflurane overdose
ESI negative ion modeXanthine25347.96371Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Carbon Dioxide
ESI negative ion modeXanthine25610.86157peak area (normalized to tissue mass)Liver Continuous isoflurane
ESI negative ion modeXanthine26114.79556Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Isoflurane overdose
ESI negative ion modeXanthine26754.28802Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Ketamine
ESI negative ion modeXanthine27196.00444peak area (normalized to tissue mass)Liver Pentobarbital
ESI negative ion modeXanthine28532.68717Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Ketamine
ESI negative ion modeXanthine29827.12066peak area (normalized to tissue mass)Liver Ketamine
ESI negative ion modeXanthine32373.27583peak area (normalized to tissue mass)Liver Continuous isoflurane
ESI negative ion modeXanthine32446.05468Peak area (normalized to tissue mass)Heart Ketamine
ESI negative ion modeXanthine32849.40071Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Pentobarbital
ESI negative ion modeXanthine34801.38336peak area (normalized to tissue mass)Liver Pentobarbital
ESI negative ion modeXanthine35937.33697Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Carbon Dioxide
ESI negative ion modeXanthine36470.2319peak area (normalized to tissue mass)Liver Pentobarbital
ESI negative ion modeXanthine36510.84596Peak areaSerum Isoflurane overdose
ESI negative ion modeXanthine48061.70817Peak area (normalized to tissue mass)Heart Pentobarbital
ESI negative ion modeXanthine50706.25363Peak area (normalized to tissue mass)Gastrocnemius (skeletal muscle) Isoflurane overdose
ESI negative ion modeXanthine51173.23394peak area (normalized to tissue mass)Liver Continuous isoflurane
ESI negative ion modeXanthine53030.54348peak area (normalized to tissue mass)Liver Continuous isoflurane
ESI negative ion modeXanthine55063.08437peak area (normalized to tissue mass)Liver Continuous isoflurane
ESI negative ion modeXanthine71023.0903peak area (normalized to tissue mass)Liver Ketamine
ESI negative ion modeXanthine74218.42461Peak areaSerum Ketamine
ESI negative ion modeXanthine86180.1867Peak area (normalized to tissue mass)Heart Ketamine
ESI negative ion modeXanthine87788.96876Peak areaSerum Continuous isoflurane
ESI negative ion modeXanthine91028.39871peak area (normalized to tissue mass)Liver Continuous isoflurane
ESI negative ion modeXanthine93068.03202peak area (normalized to tissue mass)Liver Ketamine
ESI negative ion modeXanthine105494.3656Peak area (normalized to tissue mass)Heart Ketamine
ESI negative ion modeXanthine116738.9413Peak area (normalized to tissue mass)Heart Ketamine
ESI negative ion modeXanthine152950.7667peak area (normalized to tissue mass)Liver Ketamine
ESI negative ion modeXanthine163022.076Peak area (normalized to tissue mass)Heart Cervical Dislocation
ESI negative ion modeXanthine163327.1656Peak area (normalized to tissue mass)Heart Isoflurane overdose
ESI negative ion modeXanthine179434.4116Peak area (normalized to tissue mass)Heart Cervical Dislocation
ESI negative ion modeXanthine193396.7917Peak area (normalized to tissue mass)Heart Ketamine
ESI negative ion modeXanthine198459.2358Peak area (normalized to tissue mass)Heart Isoflurane overdose
ESI negative ion modeXanthine214785.94Peak area (normalized to tissue mass)Heart Cervical Dislocation
ESI negative ion modeXanthine218889.7416Peak area (normalized to tissue mass)Heart Cervical Dislocation
ESI negative ion modeXanthine219617.7216peak area (normalized to tissue mass)Liver Ketamine
ESI negative ion modeXanthine238446.784Peak area (normalized to tissue mass)Heart Carbon Dioxide
ESI negative ion modeXanthine239714.451Peak area (normalized to tissue mass)Heart Isoflurane overdose
ESI negative ion modeXanthine250097.5106Peak area (normalized to tissue mass)Heart Cervical Dislocation
ESI negative ion modeXanthine263251.0193Peak area (normalized to tissue mass)Heart Carbon Dioxide
ESI negative ion modeXanthine271966.6806Peak area (normalized to tissue mass)Heart Cervical Dislocation
ESI negative ion modeXanthine272728.3216Peak area (normalized to tissue mass)Heart Carbon Dioxide
ESI negative ion modeXanthine280135.2579Peak area (normalized to tissue mass)Heart Isoflurane overdose
ESI negative ion modeXanthine282774.9332Peak area (normalized to tissue mass)Heart Carbon Dioxide
ESI negative ion modeXanthine292437.0761Peak area (normalized to tissue mass)Heart Isoflurane overdose
ESI negative ion modeXanthine300581.9058Peak area (normalized to tissue mass)Heart Isoflurane overdose
ESI negative ion modeXanthine308520.7815peak area (normalized to tissue mass)Liver Isoflurane overdose
ESI negative ion modeXanthine314652.4013peak area (normalized to tissue mass)Liver Cervical Dislocation
ESI negative ion modeXanthine315698.5163Peak area (normalized to tissue mass)Heart Carbon Dioxide
ESI negative ion modeXanthine318168.586Peak area (normalized to tissue mass)Heart Carbon Dioxide
ESI negative ion modeXanthine318628.1515Peak area (normalized to tissue mass)Heart Isoflurane overdose
ESI negative ion modeXanthine320429.1422Peak area (normalized to tissue mass)Heart Cervical Dislocation
ESI negative ion modeXanthine334311.2907Peak area (normalized to tissue mass)Heart Carbon Dioxide
ESI negative ion modeXanthine341952.4047Peak area (normalized to tissue mass)Heart Carbon Dioxide
ESI negative ion modeXanthine350069.05peak area (normalized to tissue mass)Liver Ketamine
ESI negative ion modeXanthine357757.7045Peak area (normalized to tissue mass)Heart Carbon Dioxide
ESI negative ion modeXanthine362907.4621Peak area (normalized to tissue mass)Heart Cervical Dislocation
ESI negative ion modeXanthine404283.5021peak area (normalized to tissue mass)Liver Isoflurane overdose
ESI negative ion modeXanthine414618.7758peak area (normalized to tissue mass)Liver Isoflurane overdose

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