| Analysis | Metabolite Name | Measured Value | Units | Group | TIMEPOINT |
|---|---|---|---|---|---|
| HILIC NEGATIVE ION MODE | xanthine | 0.4715 | scaled units | Placebo | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.5266 | scaled units | Placebo | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.5741 | scaled units | Placebo | BASELINE |
| HILIC NEGATIVE ION MODE | xanthine | 0.6139 | scaled units | Placebo | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.6459 | scaled units | Placebo | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.6680 | scaled units | Low-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.6783 | scaled units | Low-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.6958 | scaled units | Low-Dose | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.6973 | scaled units | Placebo | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.6994 | scaled units | Low-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.7096 | scaled units | Low-Dose | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.7108 | scaled units | High-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.7131 | scaled units | High-Dose | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.7239 | scaled units | High-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.7315 | scaled units | Placebo | BASELINE |
| HILIC NEGATIVE ION MODE | xanthine | 0.7365 | scaled units | Placebo | -0.5HR |
| HILIC NEGATIVE ION MODE | xanthine | 0.7409 | scaled units | High-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.7510 | scaled units | Low-Dose | -0.5HR |
| HILIC NEGATIVE ION MODE | xanthine | 0.7520 | scaled units | High-Dose | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.7577 | scaled units | High-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | xanthine | 0.7585 | scaled units | High-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.7601 | scaled units | Placebo | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.7651 | scaled units | Low-Dose | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.7667 | scaled units | Low-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.7698 | scaled units | Low-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.7771 | scaled units | High-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.7785 | scaled units | Low-Dose | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.7856 | scaled units | Low-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | xanthine | 0.7865 | scaled units | Low-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.7931 | scaled units | High-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.7937 | scaled units | Low-Dose | -0.5HR |
| HILIC NEGATIVE ION MODE | xanthine | 0.7955 | scaled units | Placebo | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.8000 | scaled units | Low-Dose | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.8019 | scaled units | Placebo | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.8024 | scaled units | Low-Dose | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.8035 | scaled units | Placebo | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.8076 | scaled units | Placebo | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.8102 | scaled units | Placebo | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.8107 | scaled units | Placebo | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.8119 | scaled units | Low-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.8122 | scaled units | Placebo | -0.5HR |
| HILIC NEGATIVE ION MODE | xanthine | 0.8134 | scaled units | Placebo | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.8197 | scaled units | Low-Dose | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.8255 | scaled units | Placebo | -0.5HR |
| HILIC NEGATIVE ION MODE | xanthine | 0.8311 | scaled units | Low-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.8328 | scaled units | Low-Dose | -0.5HR |
| HILIC NEGATIVE ION MODE | xanthine | 0.8360 | scaled units | Low-Dose | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.8394 | scaled units | Placebo | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.8419 | scaled units | Placebo | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.8462 | scaled units | High-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.8506 | scaled units | High-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.8536 | scaled units | High-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.8540 | scaled units | Low-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | xanthine | 0.8545 | scaled units | Placebo | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.8598 | scaled units | Low-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.8614 | scaled units | High-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.8650 | scaled units | High-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | xanthine | 0.8784 | scaled units | Low-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.8786 | scaled units | Placebo | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.8817 | scaled units | Low-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | xanthine | 0.8876 | scaled units | High-Dose | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.8877 | scaled units | Placebo | BASELINE |
| HILIC NEGATIVE ION MODE | xanthine | 0.8984 | scaled units | Low-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | xanthine | 0.9013 | scaled units | Low-Dose | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.9016 | scaled units | Low-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | xanthine | 0.9019 | scaled units | High-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.9032 | scaled units | Placebo | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.9110 | scaled units | Low-Dose | -0.5HR |
| HILIC NEGATIVE ION MODE | xanthine | 0.9123 | scaled units | High-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.9140 | scaled units | High-Dose | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.9140 | scaled units | Placebo | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.9213 | scaled units | Placebo | -0.5HR |
| HILIC NEGATIVE ION MODE | xanthine | 0.9288 | scaled units | High-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | xanthine | 0.9289 | scaled units | Low-Dose | -0.5HR |
| HILIC NEGATIVE ION MODE | xanthine | 0.9334 | scaled units | Low-Dose | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.9360 | scaled units | High-Dose | -0.5HR |
| HILIC NEGATIVE ION MODE | xanthine | 0.9369 | scaled units | High-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | xanthine | 0.9402 | scaled units | Low-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.9411 | scaled units | High-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.9414 | scaled units | High-Dose | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.9431 | scaled units | High-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.9477 | scaled units | High-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.9478 | scaled units | Low-Dose | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.9481 | scaled units | Low-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.9495 | scaled units | Low-Dose | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.9632 | scaled units | Low-Dose | -0.5HR |
| HILIC NEGATIVE ION MODE | xanthine | 0.9722 | scaled units | Low-Dose | -0.5HR |
| HILIC NEGATIVE ION MODE | xanthine | 0.9774 | scaled units | Low-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.9860 | scaled units | Low-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.9878 | scaled units | High-Dose | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.9893 | scaled units | High-Dose | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.9945 | scaled units | Low-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 0.9998 | scaled units | Low-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.0000 | scaled units | Placebo | -0.5HR |
| HILIC NEGATIVE ION MODE | xanthine | 1.0055 | scaled units | Placebo | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.0066 | scaled units | Low-Dose | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.0100 | scaled units | Placebo | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.0120 | scaled units | High-Dose | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.0121 | scaled units | High-Dose | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.0122 | scaled units | High-Dose | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.0169 | scaled units | High-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.0222 | scaled units | Placebo | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.0230 | scaled units | Low-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.0260 | scaled units | High-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | xanthine | 1.0333 | scaled units | Placebo | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.0334 | scaled units | Low-Dose | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.0337 | scaled units | High-Dose | -0.5HR |
| HILIC NEGATIVE ION MODE | xanthine | 1.0377 | scaled units | Low-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.0378 | scaled units | Placebo | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.0386 | scaled units | Placebo | BASELINE |
| HILIC NEGATIVE ION MODE | xanthine | 1.0425 | scaled units | Placebo | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.0456 | scaled units | Low-Dose | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.0460 | scaled units | High-Dose | -0.5HR |
| HILIC NEGATIVE ION MODE | xanthine | 1.0476 | scaled units | Low-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.0534 | scaled units | Low-Dose | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.0549 | scaled units | Low-Dose | -0.5HR |
| HILIC NEGATIVE ION MODE | xanthine | 1.0575 | scaled units | High-Dose | -0.5HR |
| HILIC NEGATIVE ION MODE | xanthine | 1.0590 | scaled units | High-Dose | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.0745 | scaled units | Placebo | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.0755 | scaled units | High-Dose | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.0843 | scaled units | Low-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.0854 | scaled units | Placebo | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.0864 | scaled units | Placebo | BASELINE |
| HILIC NEGATIVE ION MODE | xanthine | 1.0869 | scaled units | Low-Dose | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.0876 | scaled units | High-Dose | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.0878 | scaled units | Low-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | xanthine | 1.0935 | scaled units | Placebo | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.0949 | scaled units | Placebo | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.0972 | scaled units | Low-Dose | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.0999 | scaled units | High-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | xanthine | 1.1059 | scaled units | High-Dose | -0.5HR |
| HILIC NEGATIVE ION MODE | xanthine | 1.1092 | scaled units | Low-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.1108 | scaled units | Placebo | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.1111 | scaled units | High-Dose | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.1114 | scaled units | High-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | xanthine | 1.1128 | scaled units | High-Dose | -0.5HR |
| HILIC NEGATIVE ION MODE | xanthine | 1.1250 | scaled units | Low-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.1424 | scaled units | Placebo | BASELINE |
| HILIC NEGATIVE ION MODE | xanthine | 1.1462 | scaled units | Low-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | xanthine | 1.1503 | scaled units | High-Dose | -0.5HR |
| HILIC NEGATIVE ION MODE | xanthine | 1.1613 | scaled units | Low-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | xanthine | 1.1657 | scaled units | Placebo | BASELINE |
| HILIC NEGATIVE ION MODE | xanthine | 1.1710 | scaled units | Low-Dose | -0.5HR |
| HILIC NEGATIVE ION MODE | xanthine | 1.1741 | scaled units | Low-Dose | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.1750 | scaled units | Low-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | xanthine | 1.1755 | scaled units | Low-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | xanthine | 1.1801 | scaled units | High-Dose | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.1865 | scaled units | High-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.1880 | scaled units | Placebo | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.1935 | scaled units | Placebo | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.1940 | scaled units | High-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | xanthine | 1.2050 | scaled units | Low-Dose | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.2078 | scaled units | High-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | xanthine | 1.2113 | scaled units | Low-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.2150 | scaled units | High-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.2285 | scaled units | Placebo | -0.5HR |
| HILIC NEGATIVE ION MODE | xanthine | 1.2324 | scaled units | Low-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | xanthine | 1.2357 | scaled units | Placebo | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.2361 | scaled units | Low-Dose | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.2412 | scaled units | High-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.2413 | scaled units | High-Dose | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.2445 | scaled units | Placebo | BASELINE |
| HILIC NEGATIVE ION MODE | xanthine | 1.2647 | scaled units | High-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | xanthine | 1.2867 | scaled units | Placebo | BASELINE |
| HILIC NEGATIVE ION MODE | xanthine | 1.2966 | scaled units | Low-Dose | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.3036 | scaled units | High-Dose | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.3086 | scaled units | Placebo | -0.5HR |
| HILIC NEGATIVE ION MODE | xanthine | 1.3163 | scaled units | Placebo | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.3332 | scaled units | Low-Dose | -0.5HR |
| HILIC NEGATIVE ION MODE | xanthine | 1.3370 | scaled units | High-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | xanthine | 1.3528 | scaled units | Placebo | BASELINE |
| HILIC NEGATIVE ION MODE | xanthine | 1.3691 | scaled units | High-Dose | -0.5HR |
| HILIC NEGATIVE ION MODE | xanthine | 1.3771 | scaled units | Placebo | -0.5HR |
| HILIC NEGATIVE ION MODE | xanthine | 1.3871 | scaled units | Placebo | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.4055 | scaled units | Placebo | -0.5HR |
| HILIC NEGATIVE ION MODE | xanthine | 1.4126 | scaled units | Placebo | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.4169 | scaled units | High-Dose | -0.5HR |
| HILIC NEGATIVE ION MODE | xanthine | 1.4172 | scaled units | High-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.4277 | scaled units | Low-Dose | -0.5HR |
| HILIC NEGATIVE ION MODE | xanthine | 1.4391 | scaled units | Low-Dose | -0.5HR |
| HILIC NEGATIVE ION MODE | xanthine | 1.4441 | scaled units | Placebo | -0.5HR |
| HILIC NEGATIVE ION MODE | xanthine | 1.4856 | scaled units | High-Dose | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.4983 | scaled units | Placebo | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.5094 | scaled units | High-Dose | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.5122 | scaled units | High-Dose | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.5688 | scaled units | High-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | xanthine | 1.7078 | scaled units | High-Dose | -0.5HR |
- UCSD Metabolomics Workbench, a resource sponsored by the Common Fund of the National Institutes of Health
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