Analysis Metabolite Name Measured Value Units Group TIMEPOINT
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.2231scaled unitsHigh-Dose -0.5HR
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.2231scaled unitsHigh-Dose +23HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.2231scaled unitsHigh-Dose +47HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.2231scaled unitsHigh-Dose +4HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.2231scaled unitsHigh-Dose +71HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.2231scaled unitsHigh-Dose BASELINE
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.2231scaled unitsLow-Dose -0.5HR
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.2231scaled unitsLow-Dose +23HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.2231scaled unitsLow-Dose +47HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.2231scaled unitsLow-Dose +4HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.2231scaled unitsLow-Dose +71HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.2231scaled unitsLow-Dose BASELINE
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.2231scaled unitsPlacebo -0.5HR
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.2231scaled unitsPlacebo +23HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.2231scaled unitsPlacebo +47HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.2231scaled unitsPlacebo +4HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.2231scaled unitsPlacebo +71HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.2231scaled unitsPlacebo BASELINE
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.4337scaled unitsLow-Dose +47HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.4728scaled unitsLow-Dose +23HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.5587scaled unitsLow-Dose +23HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.5644scaled unitsLow-Dose BASELINE
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.5796scaled unitsLow-Dose +4HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.5802scaled unitsHigh-Dose +23HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.6032scaled unitsLow-Dose +47HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.6264scaled unitsHigh-Dose +23HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.6303scaled unitsPlacebo +4HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.6374scaled unitsLow-Dose BASELINE
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.6400scaled unitsHigh-Dose +47HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.6444scaled unitsHigh-Dose +47HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.6755scaled unitsLow-Dose -0.5HR
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.6838scaled unitsLow-Dose +71HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.6884scaled unitsHigh-Dose BASELINE
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.6923scaled unitsHigh-Dose +4HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.7081scaled unitsPlacebo -0.5HR
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.7150scaled unitsLow-Dose +4HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.7254scaled unitsLow-Dose BASELINE
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.7305scaled unitsPlacebo +71HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.7344scaled unitsHigh-Dose +23HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.7383scaled unitsLow-Dose +23HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.7414scaled unitsLow-Dose +23HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.7709scaled unitsPlacebo -0.5HR
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.7773scaled unitsLow-Dose +71HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.7872scaled unitsLow-Dose +71HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.7875scaled unitsPlacebo -0.5HR
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.8090scaled unitsLow-Dose -0.5HR
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.8091scaled unitsLow-Dose +71HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.8232scaled unitsHigh-Dose +71HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.8328scaled unitsHigh-Dose -0.5HR
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.8389scaled unitsHigh-Dose +47HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.8582scaled unitsLow-Dose BASELINE
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.9014scaled unitsPlacebo BASELINE
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.9058scaled unitsHigh-Dose +23HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.9124scaled unitsPlacebo +71HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.9423scaled unitsHigh-Dose -0.5HR
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.9465scaled unitsPlacebo +47HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.9582scaled unitsHigh-Dose +4HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.9672scaled unitsPlacebo BASELINE
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.9725scaled unitsLow-Dose -0.5HR
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.9828scaled unitsLow-Dose -0.5HR
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.9843scaled unitsHigh-Dose +71HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate0.9908scaled unitsHigh-Dose BASELINE
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate1.0092scaled unitsPlacebo +71HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate1.0172scaled unitsPlacebo +47HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate1.0255scaled unitsHigh-Dose -0.5HR
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate1.0338scaled unitsLow-Dose +47HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate1.0349scaled unitsPlacebo +47HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate1.0420scaled unitsPlacebo +4HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate1.0428scaled unitsLow-Dose +71HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate1.0851scaled unitsHigh-Dose +23HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate1.0917scaled unitsPlacebo -0.5HR
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate1.1012scaled unitsPlacebo +23HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate1.1122scaled unitsLow-Dose +4HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate1.1452scaled unitsPlacebo +4HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate1.1483scaled unitsHigh-Dose +4HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate1.1501scaled unitsPlacebo +47HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate1.1553scaled unitsPlacebo BASELINE
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate1.1627scaled unitsLow-Dose BASELINE
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate1.1928scaled unitsPlacebo +4HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate1.2191scaled unitsLow-Dose BASELINE
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate1.2345scaled unitsLow-Dose +4HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate1.2758scaled unitsHigh-Dose -0.5HR
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate1.2899scaled unitsLow-Dose -0.5HR
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate1.2932scaled unitsPlacebo +23HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate1.3094scaled unitsPlacebo -0.5HR
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate1.3318scaled unitsLow-Dose +23HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate1.3535scaled unitsLow-Dose +71HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate1.3629scaled unitsLow-Dose BASELINE
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate1.3786scaled unitsLow-Dose +47HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate1.4273scaled unitsLow-Dose +23HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate1.4351scaled unitsPlacebo +71HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate1.4646scaled unitsHigh-Dose BASELINE
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate1.5062scaled unitsLow-Dose +71HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate1.5531scaled unitsLow-Dose +47HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate1.6827scaled unitsPlacebo +47HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate1.7587scaled unitsPlacebo +23HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate1.9254scaled unitsHigh-Dose +71HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate1.9556scaled unitsLow-Dose BASELINE
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate2.1329scaled unitsPlacebo -0.5HR
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate2.3772scaled unitsLow-Dose +4HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate2.4026scaled unitsHigh-Dose -0.5HR
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate2.6313scaled unitsLow-Dose -0.5HR
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate2.6346scaled unitsPlacebo BASELINE
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate2.6932scaled unitsPlacebo +71HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate3.0118scaled unitsPlacebo BASELINE
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate3.0390scaled unitsPlacebo +23HR POST INFUSION
Reversed phase NEGATIVE ION MODE4-hydroxyphenylacetate3.0392scaled unitsPlacebo BASELINE

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