Analysis Metabolite Name Measured Value Units Cell type Material Treatment
LC/MS positive ion mode[13C]-PROLINE451467Peak areaSUPM2 Media CEP-26939
LC/MS positive ion mode[13C]-PROLINE2712848Peak area293T Media K210R NPM-ALK tf
LC/MS positive ion mode[13C]-PROLINE2769364Peak area293T Media WT NPM-ALK tf
LC/MS positive ion mode[13C]-PROLINE3019447Peak area293T Media K210R NPM-ALK tf
LC/MS positive ion mode[13C]-PROLINE3209623Peak area293T Media WT NPM-ALK tf
LC/MS positive ion mode[13C]-PROLINE3357658Peak area293T Media WT NPM-ALK tf
LC/MS positive ion mode[13C]-PROLINE3385107Peak area293T Media K210R NPM-ALK tf
LC/MS positive ion mode[13C]-PROLINE3500897Peak area293T Media No transfection
LC/MS positive ion mode[13C]-PROLINE3554583Peak area293T Media No transfection
LC/MS positive ion mode[13C]-PROLINE3560229Peak area293T Media K210R NPM-ALK tf
LC/MS positive ion mode[13C]-PROLINE3618923Peak area293T Media No transfection
LC/MS positive ion mode[13C]-PROLINE3693046Peak area293T Media No transfection
LC/MS positive ion mode[13C]-PROLINE3697179Peak area293T Media No transfection
LC/MS positive ion mode[13C]-PROLINE3743595Peak area293T Media K210R NPM-ALK tf
LC/MS positive ion mode[13C]-PROLINE3743907Peak area293T Media WT NPM-ALK tf
LC/MS positive ion mode[13C]-PROLINE3982883Peak areaSR786 Media DMSO
LC/MS positive ion mode[13C]-PROLINE4095626Peak areaSR786 Media DMSO
LC/MS positive ion mode[13C]-PROLINE4268454Peak areaDEL Media CEP-26939
LC/MS positive ion mode[13C]-PROLINE4496529Peak areaDEL Media DMSO
LC/MS positive ion mode[13C]-PROLINE4510185Peak areaSR786 Media CEP-26939
LC/MS positive ion mode[13C]-PROLINE4596810Peak areaDEL Media DMSO
LC/MS positive ion mode[13C]-PROLINE4682962Peak areaDEL Media DMSO
LC/MS positive ion mode[13C]-PROLINE4741495Peak areaSUPM2 Media DMSO
LC/MS positive ion mode[13C]-PROLINE4775152Peak areaDEL Media CEP-26939
LC/MS positive ion mode[13C]-PROLINE4790230Peak areaSUPM2 Media DMSO
LC/MS positive ion mode[13C]-PROLINE4793037Peak areaSUPM2 Media CEP-26939
LC/MS positive ion mode[13C]-PROLINE4809749Peak areaSR786 Media CEP-26939
LC/MS positive ion mode[13C]-PROLINE4830097Peak areaSR786 Media DMSO
LC/MS positive ion mode[13C]-PROLINE4852150Peak areaSUDHL-1 Media CEP-26939
LC/MS positive ion mode[13C]-PROLINE4917103Peak areaSR786 Media CEP-26939
LC/MS positive ion mode[13C]-PROLINE5036004Peak areaDEL Media CEP-26939
LC/MS positive ion mode[13C]-PROLINE5067627Peak areaSR786 Media CEP-26939
LC/MS positive ion mode[13C]-PROLINE5090065Peak areaSUDHL-1 Media DMSO
LC/MS positive ion mode[13C]-PROLINE5113797Peak areaDEL Media DMSO
LC/MS positive ion mode[13C]-PROLINE5188421Peak areaDEL Media CEP-26939
LC/MS positive ion mode[13C]-PROLINE5192164Peak areaSUPM2 Media DMSO
LC/MS positive ion mode[13C]-PROLINE5206057Peak areaDEL Media DMSO
LC/MS positive ion mode[13C]-PROLINE5253028Peak areaSUDHL-1 Media CEP-26939
LC/MS positive ion mode[13C]-PROLINE5280305Peak areaSUDHL-1 Media CEP-26939
LC/MS positive ion mode[13C]-PROLINE5347704Peak areaDEL Media CEP-26939
LC/MS positive ion mode[13C]-PROLINE5350704Peak areaSUDHL-1 Media DMSO
LC/MS positive ion mode[13C]-PROLINE5396472Peak areaSR786 Media CEP-26939
LC/MS positive ion mode[13C]-PROLINE5421694Peak area293T Media WT NPM-ALK tf
LC/MS positive ion mode[13C]-PROLINE5470433Peak areaSUDHL-1 Media DMSO
LC/MS positive ion mode[13C]-PROLINE5639411Peak areaSUDHL-1 Media DMSO
LC/MS positive ion mode[13C]-PROLINE5741116Peak areaSUPM2 Media DMSO
LC/MS positive ion mode[13C]-PROLINE5748484Peak areaSR786 Media DMSO
LC/MS positive ion mode[13C]-PROLINE5787178Peak areaSUDHL-1 Media CEP-26939
LC/MS positive ion mode[13C]-PROLINE5798372Peak areaSUDHL-1 Media DMSO
LC/MS positive ion mode[13C]-PROLINE5830650Peak areaSUPM2 Media CEP-26939
LC/MS positive ion mode[13C]-PROLINE5912066Peak areaSUPM2 Media CEP-26939
LC/MS positive ion mode[13C]-PROLINE6037174Peak areaSUPM2 Media CEP-26939
LC/MS positive ion mode[13C]-PROLINE6153154Peak areaSUDHL-1 Media CEP-26939
LC/MS positive ion mode[13C]-PROLINE6443890Peak areaSR786 Media DMSO
LC/MS positive ion mode[13C]-PROLINE6616350Peak areaSUPM2 Media DMSO
LC/MS positive ion mode[13C]-PROLINE22886025Peak areaDEL Cells CEP-26939
LC/MS positive ion mode[13C]-PROLINE24224845Peak area293T Cells WT NPM-ALK tf
LC/MS positive ion mode[13C]-PROLINE24643997Peak areaDEL Cells CEP-26939
LC/MS positive ion mode[13C]-PROLINE24703669Peak areaDEL Cells CEP-26939
LC/MS positive ion mode[13C]-PROLINE25169447Peak areaDEL Cells CEP-26939
LC/MS positive ion mode[13C]-PROLINE25879866Peak area293T Cells WT NPM-ALK tf
LC/MS positive ion mode[13C]-PROLINE25910978Peak area293T Cells K210R NPM-ALK tf
LC/MS positive ion mode[13C]-PROLINE25938294Peak area293T Cells K210R NPM-ALK tf
LC/MS positive ion mode[13C]-PROLINE26341458Peak area293T Cells WT NPM-ALK tf
LC/MS positive ion mode[13C]-PROLINE26957339Peak area293T Cells K210R NPM-ALK tf
LC/MS positive ion mode[13C]-PROLINE26998530Peak areaDEL Cells CEP-26939
LC/MS positive ion mode[13C]-PROLINE27156854Peak area293T Cells WT NPM-ALK tf
LC/MS positive ion mode[13C]-PROLINE27398526Peak area293T Cells No transfection
LC/MS positive ion mode[13C]-PROLINE28104570Peak area293T Cells K210R NPM-ALK tf
LC/MS positive ion mode[13C]-PROLINE28992792Peak area293T Cells WT NPM-ALK tf
LC/MS positive ion mode[13C]-PROLINE29164796Peak area293T Cells No transfection
LC/MS positive ion mode[13C]-PROLINE29535592Peak area293T Cells No transfection
LC/MS positive ion mode[13C]-PROLINE29883703Peak area293T Cells No transfection
LC/MS positive ion mode[13C]-PROLINE30496098Peak areaSR786 Cells CEP-26939
LC/MS positive ion mode[13C]-PROLINE30636151Peak area293T Cells K210R NPM-ALK tf
LC/MS positive ion mode[13C]-PROLINE30718033Peak areaSUDHL-1 Cells DMSO
LC/MS positive ion mode[13C]-PROLINE32077018Peak areaDEL Cells DMSO
LC/MS positive ion mode[13C]-PROLINE32280487Peak areaSR786 Cells DMSO
LC/MS positive ion mode[13C]-PROLINE32520710Peak areaSR786 Cells CEP-26939
LC/MS positive ion mode[13C]-PROLINE33358233Peak areaSR786 Cells DMSO
LC/MS positive ion mode[13C]-PROLINE33450680Peak areaSR786 Cells CEP-26939
LC/MS positive ion mode[13C]-PROLINE34203234Peak areaSUDHL-1 Cells DMSO
LC/MS positive ion mode[13C]-PROLINE34336689Peak area293T Cells No transfection
LC/MS positive ion mode[13C]-PROLINE35688136Peak areaSUDHL-1 Cells DMSO
LC/MS positive ion mode[13C]-PROLINE35690883Peak areaSUDHL-1 Cells DMSO
LC/MS positive ion mode[13C]-PROLINE35733450Peak areaSUDHL-1 Cells DMSO
LC/MS positive ion mode[13C]-PROLINE36595128Peak areaSR786 Cells CEP-26939
LC/MS positive ion mode[13C]-PROLINE36771768Peak areaSR786 Cells CEP-26939
LC/MS positive ion mode[13C]-PROLINE37293415Peak areaSR786 Cells DMSO
LC/MS positive ion mode[13C]-PROLINE38009224Peak areaDEL Cells DMSO
LC/MS positive ion mode[13C]-PROLINE38169683Peak areaSR786 Cells DMSO
LC/MS positive ion mode[13C]-PROLINE38256744Peak areaSR786 Cells DMSO
LC/MS positive ion mode[13C]-PROLINE40956321Peak areaSUPM2 Cells DMSO
LC/MS positive ion mode[13C]-PROLINE41200588Peak areaDEL Cells DMSO
LC/MS positive ion mode[13C]-PROLINE42151478Peak areaSUPM2 Cells DMSO
LC/MS positive ion mode[13C]-PROLINE42473584Peak areaDEL Cells DMSO
LC/MS positive ion mode[13C]-PROLINE42791602Peak areaSUPM2 Cells DMSO
LC/MS positive ion mode[13C]-PROLINE45810479Peak areaSUPM2 Cells DMSO
LC/MS positive ion mode[13C]-PROLINE48764683Peak areaSUPM2 Cells DMSO
LC/MS positive ion mode[13C]-PROLINE51431396Peak areaSUDHL-1 Cells CEP-26939
LC/MS positive ion mode[13C]-PROLINE53036093Peak areaSUPM2 Cells CEP-26939
LC/MS positive ion mode[13C]-PROLINE53428012Peak areaSUDHL-1 Cells CEP-26939
LC/MS positive ion mode[13C]-PROLINE55032058Peak areaSUDHL-1 Cells CEP-26939
LC/MS positive ion mode[13C]-PROLINE56788351Peak areaSUPM2 Cells CEP-26939
LC/MS positive ion mode[13C]-PROLINE57845076Peak areaSUPM2 Cells CEP-26939
LC/MS positive ion mode[13C]-PROLINE59204744Peak areaDEL Cells DMSO
LC/MS positive ion mode[13C]-PROLINE60400328Peak areaSUPM2 Cells CEP-26939
LC/MS positive ion mode[13C]-PROLINE60401430Peak areaSUPM2 Cells CEP-26939
LC/MS positive ion mode[13C]-PROLINE63238058Peak areaSUDHL-1 Cells CEP-26939
LC/MS positive ion mode[13C]-PROLINEPeak areaSUDHL-1 Cells CEP-26939
LC/MS positive ion modePROLINE2710499Peak areaSUPM2 Media CEP-26939
LC/MS positive ion modePROLINE18559436Peak areaSR786 Media DMSO
LC/MS positive ion modePROLINE21922789Peak areaDEL Media CEP-26939
LC/MS positive ion modePROLINE22302090Peak areaSR786 Media DMSO
LC/MS positive ion modePROLINE22528097Peak areaDEL Media DMSO
LC/MS positive ion modePROLINE23132354Peak areaDEL Media DMSO
LC/MS positive ion modePROLINE23228329Peak areaDEL Media DMSO
LC/MS positive ion modePROLINE23324749Peak areaSR786 Media DMSO
LC/MS positive ion modePROLINE23799848Peak areaSR786 Media CEP-26939
LC/MS positive ion modePROLINE23831969Peak areaDEL Media CEP-26939
LC/MS positive ion modePROLINE24225692Peak areaSUPM2 Media DMSO
LC/MS positive ion modePROLINE24340329Peak areaSR786 Media CEP-26939
LC/MS positive ion modePROLINE24692915Peak areaSUDHL-1 Media CEP-26939
LC/MS positive ion modePROLINE24764538Peak areaSUPM2 Media DMSO
LC/MS positive ion modePROLINE24890763Peak areaSUDHL-1 Media DMSO
LC/MS positive ion modePROLINE24902676Peak areaSUDHL-1 Media DMSO
LC/MS positive ion modePROLINE24927661Peak areaDEL Media DMSO
LC/MS positive ion modePROLINE24971103Peak areaDEL Media CEP-26939
LC/MS positive ion modePROLINE24978601Peak areaSR786 Media CEP-26939
LC/MS positive ion modePROLINE25026082Peak areaSR786 Media CEP-26939
LC/MS positive ion modePROLINE25295938Peak areaSUPM2 Media CEP-26939
LC/MS positive ion modePROLINE25433841Peak areaDEL Media DMSO
LC/MS positive ion modePROLINE25563713Peak areaSUPM2 Media DMSO
LC/MS positive ion modePROLINE25898195Peak areaDEL Media CEP-26939
LC/MS positive ion modePROLINE25910507Peak areaSR786 Media CEP-26939
LC/MS positive ion modePROLINE26136079Peak areaSUDHL-1 Media DMSO
LC/MS positive ion modePROLINE26286066Peak areaDEL Media CEP-26939
LC/MS positive ion modePROLINE26528371Peak areaSUDHL-1 Media DMSO
LC/MS positive ion modePROLINE27384302Peak areaSUPM2 Media DMSO
LC/MS positive ion modePROLINE27395335Peak area293T Media K210R NPM-ALK tf
LC/MS positive ion modePROLINE27402555Peak area293T Media WT NPM-ALK tf
LC/MS positive ion modePROLINE27836989Peak areaSUDHL-1 Media CEP-26939
LC/MS positive ion modePROLINE28035210Peak areaSUDHL-1 Media DMSO
LC/MS positive ion modePROLINE28264792Peak areaSR786 Media DMSO
LC/MS positive ion modePROLINE28345335Peak areaSUDHL-1 Media CEP-26939
LC/MS positive ion modePROLINE28445558Peak areaSUPM2 Media CEP-26939
LC/MS positive ion modePROLINE28486447Peak areaSUDHL-1 Media CEP-26939
LC/MS positive ion modePROLINE28702087Peak areaSUPM2 Media CEP-26939
LC/MS positive ion modePROLINE28978569Peak area293T Media WT NPM-ALK tf
LC/MS positive ion modePROLINE29172684Peak areaSUPM2 Media DMSO
LC/MS positive ion modePROLINE29303546Peak areaSUPM2 Media CEP-26939
LC/MS positive ion modePROLINE29931108Peak areaSR786 Media DMSO
LC/MS positive ion modePROLINE30258802Peak area293T Media K210R NPM-ALK tf
LC/MS positive ion modePROLINE30505261Peak area293T Media K210R NPM-ALK tf
LC/MS positive ion modePROLINE30608162Peak areaSUDHL-1 Media CEP-26939
LC/MS positive ion modePROLINE31124560Peak area293T Media WT NPM-ALK tf
LC/MS positive ion modePROLINE34917157Peak area293T Media K210R NPM-ALK tf
LC/MS positive ion modePROLINE34944313Peak area293T Media WT NPM-ALK tf
LC/MS positive ion modePROLINE35353333Peak area293T Media K210R NPM-ALK tf
LC/MS positive ion modePROLINE35580971Peak area293T Media No transfection
LC/MS positive ion modePROLINE36126244Peak area293T Media No transfection
LC/MS positive ion modePROLINE37248694Peak area293T Media No transfection
LC/MS positive ion modePROLINE37671821Peak area293T Media No transfection
LC/MS positive ion modePROLINE37965851Peak area293T Media No transfection
LC/MS positive ion modePROLINE53116898Peak area293T Media WT NPM-ALK tf
LC/MS positive ion modePROLINE65778458Peak area293T Cells WT NPM-ALK tf
LC/MS positive ion modePROLINE67845513Peak area293T Cells K210R NPM-ALK tf
LC/MS positive ion modePROLINE69032278Peak area293T Cells WT NPM-ALK tf
LC/MS positive ion modePROLINE69517009Peak area293T Cells K210R NPM-ALK tf
LC/MS positive ion modePROLINE69701385Peak area293T Cells No transfection
LC/MS positive ion modePROLINE69898987Peak area293T Cells No transfection
LC/MS positive ion modePROLINE70085289Peak area293T Cells No transfection
LC/MS positive ion modePROLINE70418168Peak area293T Cells No transfection
LC/MS positive ion modePROLINE70762532Peak area293T Cells WT NPM-ALK tf
LC/MS positive ion modePROLINE70780082Peak area293T Cells WT NPM-ALK tf
LC/MS positive ion modePROLINE71265825Peak area293T Cells K210R NPM-ALK tf
LC/MS positive ion modePROLINE72191217Peak area293T Cells WT NPM-ALK tf
LC/MS positive ion modePROLINE73948719Peak area293T Cells K210R NPM-ALK tf
LC/MS positive ion modePROLINE74595466Peak area293T Cells K210R NPM-ALK tf
LC/MS positive ion modePROLINE79491254Peak area293T Cells No transfection
LC/MS positive ion modePROLINE103623483Peak areaDEL Cells DMSO
LC/MS positive ion modePROLINE111446400Peak areaDEL Cells DMSO
LC/MS positive ion modePROLINE114684257Peak areaDEL Cells DMSO
LC/MS positive ion modePROLINE118692074Peak areaDEL Cells DMSO
LC/MS positive ion modePROLINE124411044Peak areaDEL Cells CEP-26939
LC/MS positive ion modePROLINE126061934Peak areaSR786 Cells DMSO
LC/MS positive ion modePROLINE127142779Peak areaDEL Cells DMSO
LC/MS positive ion modePROLINE127419725Peak areaDEL Cells CEP-26939
LC/MS positive ion modePROLINE129928861Peak areaDEL Cells CEP-26939
LC/MS positive ion modePROLINE133216319Peak areaSR786 Cells CEP-26939
LC/MS positive ion modePROLINE134503026Peak areaSR786 Cells CEP-26939
LC/MS positive ion modePROLINE136523083Peak areaDEL Cells CEP-26939
LC/MS positive ion modePROLINE139322455Peak areaDEL Cells CEP-26939
LC/MS positive ion modePROLINE139704979Peak areaSR786 Cells DMSO
LC/MS positive ion modePROLINE140695414Peak areaSR786 Cells CEP-26939
LC/MS positive ion modePROLINE140850616Peak areaSR786 Cells CEP-26939
LC/MS positive ion modePROLINE144160787Peak areaSR786 Cells DMSO
LC/MS positive ion modePROLINE146743027Peak areaSUPM2 Cells CEP-26939
LC/MS positive ion modePROLINE146967821Peak areaSR786 Cells DMSO
LC/MS positive ion modePROLINE149818642Peak areaSR786 Cells DMSO

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