| Analysis | Metabolite Name | Measured Value | Units | Group | TIMEPOINT |
|---|---|---|---|---|---|
| HILIC NEGATIVE ION MODE | fumarate | 0.4676 | scaled units | Low-Dose | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.5453 | scaled units | Low-Dose | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.6021 | scaled units | Low-Dose | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.6181 | scaled units | Placebo | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.6399 | scaled units | Low-Dose | -0.5HR |
| HILIC NEGATIVE ION MODE | fumarate | 0.6490 | scaled units | Low-Dose | -0.5HR |
| HILIC NEGATIVE ION MODE | fumarate | 0.6560 | scaled units | Low-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.6624 | scaled units | High-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.6797 | scaled units | High-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | fumarate | 0.6905 | scaled units | High-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | fumarate | 0.7028 | scaled units | Low-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | fumarate | 0.7111 | scaled units | Low-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.7369 | scaled units | High-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.7387 | scaled units | High-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.7408 | scaled units | Low-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.7409 | scaled units | High-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.7490 | scaled units | Placebo | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.7570 | scaled units | High-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.7657 | scaled units | Placebo | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.7695 | scaled units | Low-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.7709 | scaled units | Low-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | fumarate | 0.7721 | scaled units | Low-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.7733 | scaled units | Low-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.7735 | scaled units | Low-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.7902 | scaled units | High-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.7912 | scaled units | High-Dose | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.7926 | scaled units | Low-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.8029 | scaled units | Low-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.8128 | scaled units | High-Dose | -0.5HR |
| HILIC NEGATIVE ION MODE | fumarate | 0.8128 | scaled units | High-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | fumarate | 0.8151 | scaled units | Low-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.8188 | scaled units | Low-Dose | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.8229 | scaled units | Low-Dose | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.8280 | scaled units | Low-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | fumarate | 0.8341 | scaled units | High-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.8388 | scaled units | Placebo | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.8405 | scaled units | High-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.8452 | scaled units | Low-Dose | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.8477 | scaled units | High-Dose | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.8505 | scaled units | Low-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.8542 | scaled units | Placebo | BASELINE |
| HILIC NEGATIVE ION MODE | fumarate | 0.8555 | scaled units | High-Dose | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.8596 | scaled units | Placebo | -0.5HR |
| HILIC NEGATIVE ION MODE | fumarate | 0.8626 | scaled units | Low-Dose | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.8626 | scaled units | Low-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | fumarate | 0.8649 | scaled units | Placebo | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.8676 | scaled units | Placebo | BASELINE |
| HILIC NEGATIVE ION MODE | fumarate | 0.8754 | scaled units | Placebo | BASELINE |
| HILIC NEGATIVE ION MODE | fumarate | 0.8755 | scaled units | Low-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.8775 | scaled units | High-Dose | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.8816 | scaled units | Low-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.8819 | scaled units | Low-Dose | -0.5HR |
| HILIC NEGATIVE ION MODE | fumarate | 0.8835 | scaled units | High-Dose | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.8903 | scaled units | Low-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.8944 | scaled units | Low-Dose | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.8945 | scaled units | Low-Dose | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.8959 | scaled units | Low-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | fumarate | 0.8965 | scaled units | Placebo | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.9009 | scaled units | Low-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.9033 | scaled units | High-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | fumarate | 0.9063 | scaled units | Low-Dose | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.9072 | scaled units | High-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.9092 | scaled units | Placebo | BASELINE |
| HILIC NEGATIVE ION MODE | fumarate | 0.9133 | scaled units | Low-Dose | -0.5HR |
| HILIC NEGATIVE ION MODE | fumarate | 0.9157 | scaled units | High-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | fumarate | 0.9176 | scaled units | Low-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | fumarate | 0.9207 | scaled units | Low-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.9240 | scaled units | High-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.9245 | scaled units | Low-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.9253 | scaled units | Low-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.9266 | scaled units | Placebo | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.9301 | scaled units | High-Dose | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.9314 | scaled units | High-Dose | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.9333 | scaled units | Low-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.9350 | scaled units | High-Dose | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.9380 | scaled units | High-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | fumarate | 0.9465 | scaled units | Low-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.9473 | scaled units | High-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.9498 | scaled units | High-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | fumarate | 0.9501 | scaled units | Low-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.9593 | scaled units | Placebo | -0.5HR |
| HILIC NEGATIVE ION MODE | fumarate | 0.9689 | scaled units | Low-Dose | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.9698 | scaled units | High-Dose | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.9737 | scaled units | High-Dose | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.9751 | scaled units | High-Dose | -0.5HR |
| HILIC NEGATIVE ION MODE | fumarate | 0.9796 | scaled units | Placebo | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.9796 | scaled units | Placebo | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.9837 | scaled units | High-Dose | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.9895 | scaled units | Low-Dose | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.9897 | scaled units | Placebo | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.9898 | scaled units | High-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 0.9914 | scaled units | High-Dose | -0.5HR |
| HILIC NEGATIVE ION MODE | fumarate | 0.9974 | scaled units | Low-Dose | -0.5HR |
| HILIC NEGATIVE ION MODE | fumarate | 1.0000 | scaled units | Placebo | -0.5HR |
| HILIC NEGATIVE ION MODE | fumarate | 1.0068 | scaled units | High-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.0086 | scaled units | High-Dose | -0.5HR |
| HILIC NEGATIVE ION MODE | fumarate | 1.0105 | scaled units | Low-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | fumarate | 1.0144 | scaled units | Placebo | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.0146 | scaled units | Placebo | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.0151 | scaled units | Low-Dose | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.0209 | scaled units | Placebo | BASELINE |
| HILIC NEGATIVE ION MODE | fumarate | 1.0259 | scaled units | High-Dose | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.0266 | scaled units | Low-Dose | -0.5HR |
| HILIC NEGATIVE ION MODE | fumarate | 1.0285 | scaled units | High-Dose | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.0335 | scaled units | Low-Dose | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.0351 | scaled units | High-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.0389 | scaled units | High-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.0430 | scaled units | High-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.0434 | scaled units | Placebo | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.0468 | scaled units | High-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | fumarate | 1.0504 | scaled units | Low-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.0535 | scaled units | Low-Dose | -0.5HR |
| HILIC NEGATIVE ION MODE | fumarate | 1.0588 | scaled units | Low-Dose | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.0615 | scaled units | High-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.0646 | scaled units | Low-Dose | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.0655 | scaled units | High-Dose | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.0665 | scaled units | Placebo | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.0669 | scaled units | Placebo | BASELINE |
| HILIC NEGATIVE ION MODE | fumarate | 1.0702 | scaled units | High-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.0719 | scaled units | High-Dose | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.0721 | scaled units | High-Dose | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.0733 | scaled units | Low-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | fumarate | 1.0766 | scaled units | Placebo | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.0788 | scaled units | Placebo | BASELINE |
| HILIC NEGATIVE ION MODE | fumarate | 1.0957 | scaled units | Low-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | fumarate | 1.0980 | scaled units | Placebo | -0.5HR |
| HILIC NEGATIVE ION MODE | fumarate | 1.1009 | scaled units | Placebo | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.1026 | scaled units | Placebo | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.1034 | scaled units | Low-Dose | -0.5HR |
| HILIC NEGATIVE ION MODE | fumarate | 1.1039 | scaled units | High-Dose | -0.5HR |
| HILIC NEGATIVE ION MODE | fumarate | 1.1058 | scaled units | Low-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.1166 | scaled units | Low-Dose | -0.5HR |
| HILIC NEGATIVE ION MODE | fumarate | 1.1273 | scaled units | Low-Dose | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.1309 | scaled units | Placebo | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.1346 | scaled units | Low-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | fumarate | 1.1373 | scaled units | Placebo | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.1412 | scaled units | Placebo | -0.5HR |
| HILIC NEGATIVE ION MODE | fumarate | 1.1496 | scaled units | Placebo | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.1509 | scaled units | High-Dose | -0.5HR |
| HILIC NEGATIVE ION MODE | fumarate | 1.1525 | scaled units | Placebo | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.1552 | scaled units | Low-Dose | -0.5HR |
| HILIC NEGATIVE ION MODE | fumarate | 1.1560 | scaled units | Placebo | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.1651 | scaled units | Low-Dose | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.1654 | scaled units | High-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | fumarate | 1.1686 | scaled units | Placebo | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.1778 | scaled units | High-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.1850 | scaled units | Low-Dose | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.1936 | scaled units | Placebo | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.1942 | scaled units | Low-Dose | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.1999 | scaled units | Placebo | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.2017 | scaled units | Low-Dose | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.2020 | scaled units | High-Dose | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.2062 | scaled units | High-Dose | -0.5HR |
| HILIC NEGATIVE ION MODE | fumarate | 1.2161 | scaled units | Placebo | -0.5HR |
| HILIC NEGATIVE ION MODE | fumarate | 1.2174 | scaled units | Placebo | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.2192 | scaled units | High-Dose | -0.5HR |
| HILIC NEGATIVE ION MODE | fumarate | 1.2217 | scaled units | Placebo | -0.5HR |
| HILIC NEGATIVE ION MODE | fumarate | 1.2217 | scaled units | Placebo | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.2281 | scaled units | Low-Dose | -0.5HR |
| HILIC NEGATIVE ION MODE | fumarate | 1.2292 | scaled units | Low-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | fumarate | 1.2318 | scaled units | Low-Dose | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.2330 | scaled units | High-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | fumarate | 1.2340 | scaled units | High-Dose | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.2341 | scaled units | Placebo | -0.5HR |
| HILIC NEGATIVE ION MODE | fumarate | 1.2376 | scaled units | High-Dose | BASELINE |
| HILIC NEGATIVE ION MODE | fumarate | 1.2385 | scaled units | High-Dose | -0.5HR |
| HILIC NEGATIVE ION MODE | fumarate | 1.2517 | scaled units | Placebo | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.2600 | scaled units | High-Dose | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.2678 | scaled units | Placebo | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.2723 | scaled units | Placebo | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.2813 | scaled units | Placebo | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.2824 | scaled units | High-Dose | -0.5HR |
| HILIC NEGATIVE ION MODE | fumarate | 1.2967 | scaled units | High-Dose | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.2970 | scaled units | Placebo | BASELINE |
| HILIC NEGATIVE ION MODE | fumarate | 1.3033 | scaled units | Placebo | +71HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.3070 | scaled units | Placebo | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.3205 | scaled units | Placebo | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.3295 | scaled units | Placebo | +4HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.3386 | scaled units | High-Dose | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.4118 | scaled units | Low-Dose | -0.5HR |
| HILIC NEGATIVE ION MODE | fumarate | 1.4207 | scaled units | Placebo | +47HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.4408 | scaled units | Placebo | BASELINE |
| HILIC NEGATIVE ION MODE | fumarate | 1.4738 | scaled units | Placebo | -0.5HR |
| HILIC NEGATIVE ION MODE | fumarate | 1.6133 | scaled units | Placebo | BASELINE |
| HILIC NEGATIVE ION MODE | fumarate | 1.6146 | scaled units | Placebo | +23HR POST INFUSION |
| HILIC NEGATIVE ION MODE | fumarate | 1.7176 | scaled units | Placebo | -0.5HR |
| HILIC NEGATIVE ION MODE | fumarate | 1.7373 | scaled units | High-Dose | +71HR POST INFUSION |
- UCSD Metabolomics Workbench, a resource sponsored by the Common Fund of the National Institutes of Health
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