| Analysis | Metabolite Name | Measured Value | Units | Genotype | U13C Glucose Labelling Timepoint |
|---|---|---|---|---|---|
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 324754.853 | Peak Area | Akita | 4 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 358928.248 | Peak Area | Wild Type | 30 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 373949.8124 | Peak Area | Akita | 4 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 468897.0924 | Peak Area | Akita | 2 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 474908.6599 | Peak Area | Akita | 3 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 479490.6115 | Peak Area | Akita | 3 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 632350.4883 | Peak Area | Akita | 1 hour |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 660642.2456 | Peak Area | Wild Type | 3 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 676932.0892 | Peak Area | Akita | 30 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 687980.7657 | Peak Area | Akita | 3 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 741926.2946 | Peak Area | Akita | 2 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 760766.7648 | Peak Area | Akita | 1 hour |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 801540.8382 | Peak Area | Akita | 4 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 809607.3433 | Peak Area | Akita | 2 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 830156.0262 | Peak Area | Wild Type | 4 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 868837.4445 | Peak Area | Wild Type | 3 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 887423.6336 | Peak Area | Wild Type | 2 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 903666.6466 | Peak Area | Akita | 3 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 907641.7585 | Peak Area | Akita | 0 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 911812.7964 | Peak Area | Akita | 4 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 945357.0059 | Peak Area | Akita | 1 hour |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 965137.9537 | Peak Area | Wild Type | 1 hour |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 985609.2162 | Peak Area | Wild Type | 4 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 1002882.692 | Peak Area | Akita | 30 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 1026631.034 | Peak Area | Wild Type | 30 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 1046939.354 | Peak Area | Wild Type | 3 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 1075219.883 | Peak Area | Akita | 0 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 1084385.44 | Peak Area | Wild Type | 3 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 1144150.213 | Peak Area | Wild Type | 4 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 1144873.285 | Peak Area | Wild Type | 30 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 1146100.931 | Peak Area | Wild Type | 0 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 1150776.603 | Peak Area | Wild Type | 2 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 1160631.974 | Peak Area | Akita | 0 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 1185683.81 | Peak Area | Wild Type | 0 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 1215268.829 | Peak Area | Wild Type | 0 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 1250277.822 | Peak Area | Wild Type | 1 hour |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 1265375.961 | Peak Area | Wild Type | 2 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 1265468.402 | Peak Area | Wild Type | 2 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 1282619.241 | Peak Area | Akita | 3 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 1286241.692 | Peak Area | Akita | 30 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 1305242.169 | Peak Area | Wild Type | 1 hour |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 1335065.013 | Peak Area | Wild Type | 4 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 1338782.329 | Peak Area | Wild Type | 3 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 1344272.187 | Peak Area | Wild Type | 30 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 1395080.504 | Peak Area | Akita | 2 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 1401006.105 | Peak Area | Akita | 4 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 1429521.061 | Peak Area | Wild Type | 1 hour |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 1481478.789 | Peak Area | Wild Type | 2 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 1485378.328 | Peak Area | Wild Type | 2 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 1510897.294 | Peak Area | Wild Type | 1 hour |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 1531587.132 | Peak Area | Wild Type | 3 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 1592140.404 | Peak Area | Wild Type | 1 hour |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 1611086.499 | Peak Area | Akita | 0 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 1630829.222 | Peak Area | Akita | 2 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 1671574.314 | Peak Area | Wild Type | 0 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 1730186.075 | Peak Area | Wild Type | 3 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 1731862.188 | Peak Area | Akita | 3 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 1766352.071 | Peak Area | Wild Type | 1 hour |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 1772674.625 | Peak Area | Akita | 1 hour |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 1775469.154 | Peak Area | Wild Type | 4 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 1815081.777 | Peak Area | Wild Type | 4 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 1831947.765 | Peak Area | Wild Type | 4 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 1848216.258 | Peak Area | Wild Type | 1 hour |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 1949566.927 | Peak Area | Wild Type | 1 hour |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 1953884.084 | Peak Area | Wild Type | 2 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 1992239.03 | Peak Area | Wild Type | 3 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 2007653.202 | Peak Area | Wild Type | 4 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 2052294.458 | Peak Area | Akita | 2 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 2058406.941 | Peak Area | Wild Type | 3 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 2083146.202 | Peak Area | Wild Type | 30 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 2086289.498 | Peak Area | Wild Type | 30 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 2123526.712 | Peak Area | Wild Type | 30 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 2179660.358 | Peak Area | Wild Type | 2 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 2184651.28 | Peak Area | Wild Type | 3 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 2246788.943 | Peak Area | Wild Type | 0 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 2259006.623 | Peak Area | Wild Type | 30 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 2271430.005 | Peak Area | Akita | 30 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 2363845.647 | Peak Area | Wild Type | 3 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 2432849.904 | Peak Area | Akita | 0 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 2477198.414 | Peak Area | Wild Type | 30 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 2516303.08 | Peak Area | Wild Type | 30 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 2541676.085 | Peak Area | Wild Type | 0 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 2542031.559 | Peak Area | Akita | 0 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 2544636.182 | Peak Area | Wild Type | 3 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 2549487.379 | Peak Area | Wild Type | 1 hour |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 2578631.559 | Peak Area | Wild Type | 30 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 2594676.212 | Peak Area | Wild Type | 2 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 2683614.044 | Peak Area | Wild Type | 4 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 2693911.524 | Peak Area | Wild Type | 30 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 2854126.102 | Peak Area | Wild Type | 0 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 2882339.034 | Peak Area | Wild Type | 2 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 2883841.893 | Peak Area | Wild Type | 1 hour |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 2923683.059 | Peak Area | Wild Type | 0 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 3002111.307 | Peak Area | Akita | 3 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 3031056.823 | Peak Area | Wild Type | 4 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 3042958.221 | Peak Area | Wild Type | 3 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 3045448.277 | Peak Area | Wild Type | 2 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 3058985.081 | Peak Area | Wild Type | 4 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 3071576.934 | Peak Area | Wild Type | 0 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 3093017.415 | Peak Area | Wild Type | 3 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 3093033.284 | Peak Area | Wild Type | 0 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 3100472.321 | Peak Area | Wild Type | 30 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 3107803.594 | Peak Area | Wild Type | 1 hour |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 3108330.585 | Peak Area | Wild Type | 3 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 3128434.671 | Peak Area | Wild Type | 0 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 3136154.366 | Peak Area | Wild Type | 2 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 3140074.272 | Peak Area | Wild Type | 4 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 3182597.294 | Peak Area | Wild Type | 4 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 3188966.851 | Peak Area | Wild Type | 3 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 3197232.101 | Peak Area | Wild Type | 0 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 3214193.954 | Peak Area | Wild Type | 1 hour |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 3231165.329 | Peak Area | Akita | 30 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 3276385.102 | Peak Area | Wild Type | 4 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 3352458.137 | Peak Area | Wild Type | 4 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 3364370.598 | Peak Area | Akita | 1 hour |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 3386950.846 | Peak Area | Wild Type | 2 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 3447428.016 | Peak Area | Wild Type | 30 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 3507129.632 | Peak Area | Wild Type | 0 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 3508877.185 | Peak Area | Wild Type | 1 hour |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 3535982.01 | Peak Area | Wild Type | 4 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 3546196.702 | Peak Area | Wild Type | 3 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 3556157.456 | Peak Area | Wild Type | 1 hour |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 3625424.442 | Peak Area | Wild Type | 2 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 3640280.247 | Peak Area | Wild Type | 3 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 3655820.972 | Peak Area | Wild Type | 2 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 3753619.304 | Peak Area | Wild Type | 2 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 3784632.831 | Peak Area | Wild Type | 1 hour |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 3837328.251 | Peak Area | Wild Type | 2 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 3945114.357 | Peak Area | Akita | 0 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 3953930.347 | Peak Area | Akita | 4 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 4145946.079 | Peak Area | Wild Type | 2 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 4169572.71 | Peak Area | Akita | 4 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 4179052.66 | Peak Area | Wild Type | 30 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 4202226.358 | Peak Area | Wild Type | 0 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 4257823.823 | Peak Area | Wild Type | 1 hour |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 4298344.136 | Peak Area | Akita | 0 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 4368793.409 | Peak Area | Wild Type | 30 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 4374632.629 | Peak Area | Wild Type | 2 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 4425780.703 | Peak Area | Wild Type | 4 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 4682751.267 | Peak Area | Akita | 3 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 4696772.6 | Peak Area | Wild Type | 4 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 4733467.454 | Peak Area | Wild Type | 2 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 4755103.056 | Peak Area | Wild Type | 30 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 4823677.41 | Peak Area | Akita | 4 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 4890424.34 | Peak Area | Akita | 30 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 4976808.696 | Peak Area | Akita | 2 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 5026261.364 | Peak Area | Wild Type | 0 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 5067831.253 | Peak Area | Akita | 1 hour |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 5099239.935 | Peak Area | Wild Type | 3 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 5145088.013 | Peak Area | Wild Type | 30 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 5159953.092 | Peak Area | Wild Type | 30 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 5169893.039 | Peak Area | Wild Type | 30 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 5210458.184 | Peak Area | Akita | 30 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 5213949.34 | Peak Area | Wild Type | 0 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 5369909.526 | Peak Area | Wild Type | 4 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 5403735.491 | Peak Area | Akita | 2 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 5427488.19 | Peak Area | Wild Type | 1 hour |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 5581535.188 | Peak Area | Akita | 1 hour |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 5741101.243 | Peak Area | Akita | 1 hour |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 5965874.606 | Peak Area | Akita | 30 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 6137527.472 | Peak Area | Wild Type | 4 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 6244206.358 | Peak Area | Akita | 3 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 6249953.864 | Peak Area | Akita | 2 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 6328125.41 | Peak Area | Wild Type | 1 hour |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 6408893.932 | Peak Area | Wild Type | 1 hour |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 6520276.215 | Peak Area | Wild Type | 3 hours |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 6571805.937 | Peak Area | Wild Type | 0 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 6787930.84 | Peak Area | Akita | 0 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 6897875.387 | Peak Area | Wild Type | 0 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 7203720.635 | Peak Area | Wild Type | 0 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 8364006.933 | Peak Area | Akita | 30 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 9187742.935 | Peak Area | Wild Type | 0 minutes |
| HILIC NEGATIVE ION MODE | alpha-ketoglutarate | 9897724.442 | Peak Area | Akita | 1 hour |
- UCSD Metabolomics Workbench, a resource sponsored by the Common Fund of the National Institutes of Health
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