| Analysis | Metabolite Name | Measured Value | Units | Cell type | Material | Treatment |
|---|---|---|---|---|---|---|
| LC/MS positive ion mode | [13C]-LYSINE | 122492 | Peak area | 293T | Media | K210R NPM-ALK tf |
| LC/MS positive ion mode | [13C]-LYSINE | 135219 | Peak area | SUPM2 | Media | CEP-26939 |
| LC/MS positive ion mode | [13C]-LYSINE | 181742 | Peak area | DEL | Media | CEP-26939 |
| LC/MS positive ion mode | [13C]-LYSINE | 185538 | Peak area | DEL | Media | CEP-26939 |
| LC/MS positive ion mode | [13C]-LYSINE | 188118 | Peak area | 293T | Media | WT NPM-ALK tf |
| LC/MS positive ion mode | [13C]-LYSINE | 194288 | Peak area | SR786 | Media | DMSO |
| LC/MS positive ion mode | [13C]-LYSINE | 195120 | Peak area | 293T | Media | WT NPM-ALK tf |
| LC/MS positive ion mode | [13C]-LYSINE | 200888 | Peak area | 293T | Media | No transfection |
| LC/MS positive ion mode | [13C]-LYSINE | 202286 | Peak area | SR786 | Media | CEP-26939 |
| LC/MS positive ion mode | [13C]-LYSINE | 204727 | Peak area | 293T | Media | K210R NPM-ALK tf |
| LC/MS positive ion mode | [13C]-LYSINE | 211389 | Peak area | DEL | Media | CEP-26939 |
| LC/MS positive ion mode | [13C]-LYSINE | 211927 | Peak area | DEL | Media | DMSO |
| LC/MS positive ion mode | [13C]-LYSINE | 213868 | Peak area | SUDHL-1 | Media | DMSO |
| LC/MS positive ion mode | [13C]-LYSINE | 214520 | Peak area | SUDHL-1 | Media | CEP-26939 |
| LC/MS positive ion mode | [13C]-LYSINE | 214972 | Peak area | SR786 | Media | CEP-26939 |
| LC/MS positive ion mode | [13C]-LYSINE | 218665 | Peak area | SR786 | Media | DMSO |
| LC/MS positive ion mode | [13C]-LYSINE | 219067 | Peak area | DEL | Media | DMSO |
| LC/MS positive ion mode | [13C]-LYSINE | 220148 | Peak area | DEL | Media | CEP-26939 |
| LC/MS positive ion mode | [13C]-LYSINE | 220222 | Peak area | 293T | Media | WT NPM-ALK tf |
| LC/MS positive ion mode | [13C]-LYSINE | 221340 | Peak area | SUPM2 | Media | DMSO |
| LC/MS positive ion mode | [13C]-LYSINE | 221677 | Peak area | DEL | Media | DMSO |
| LC/MS positive ion mode | [13C]-LYSINE | 222477 | Peak area | SR786 | Media | DMSO |
| LC/MS positive ion mode | [13C]-LYSINE | 222606 | Peak area | DEL | Media | DMSO |
| LC/MS positive ion mode | [13C]-LYSINE | 223269 | Peak area | SUDHL-1 | Media | DMSO |
| LC/MS positive ion mode | [13C]-LYSINE | 223906 | Peak area | DEL | Media | DMSO |
| LC/MS positive ion mode | [13C]-LYSINE | 224961 | Peak area | SUDHL-1 | Media | CEP-26939 |
| LC/MS positive ion mode | [13C]-LYSINE | 226127 | Peak area | SUPM2 | Media | CEP-26939 |
| LC/MS positive ion mode | [13C]-LYSINE | 227890 | Peak area | 293T | Media | No transfection |
| LC/MS positive ion mode | [13C]-LYSINE | 228109 | Peak area | 293T | Media | WT NPM-ALK tf |
| LC/MS positive ion mode | [13C]-LYSINE | 230248 | Peak area | SUPM2 | Media | CEP-26939 |
| LC/MS positive ion mode | [13C]-LYSINE | 230986 | Peak area | SUDHL-1 | Media | DMSO |
| LC/MS positive ion mode | [13C]-LYSINE | 231081 | Peak area | 293T | Media | No transfection |
| LC/MS positive ion mode | [13C]-LYSINE | 232350 | Peak area | SUPM2 | Media | CEP-26939 |
| LC/MS positive ion mode | [13C]-LYSINE | 235202 | Peak area | SR786 | Media | CEP-26939 |
| LC/MS positive ion mode | [13C]-LYSINE | 236183 | Peak area | SUDHL-1 | Media | DMSO |
| LC/MS positive ion mode | [13C]-LYSINE | 236369 | Peak area | SUDHL-1 | Media | CEP-26939 |
| LC/MS positive ion mode | [13C]-LYSINE | 237368 | Peak area | SR786 | Media | DMSO |
| LC/MS positive ion mode | [13C]-LYSINE | 238086 | Peak area | 293T | Media | WT NPM-ALK tf |
| LC/MS positive ion mode | [13C]-LYSINE | 239301 | Peak area | 293T | Media | K210R NPM-ALK tf |
| LC/MS positive ion mode | [13C]-LYSINE | 239827 | Peak area | SR786 | Media | CEP-26939 |
| LC/MS positive ion mode | [13C]-LYSINE | 240044 | Peak area | DEL | Media | CEP-26939 |
| LC/MS positive ion mode | [13C]-LYSINE | 240923 | Peak area | SR786 | Media | CEP-26939 |
| LC/MS positive ion mode | [13C]-LYSINE | 241376 | Peak area | 293T | Media | K210R NPM-ALK tf |
| LC/MS positive ion mode | [13C]-LYSINE | 242355 | Peak area | 293T | Media | No transfection |
| LC/MS positive ion mode | [13C]-LYSINE | 242432 | Peak area | SUPM2 | Media | DMSO |
| LC/MS positive ion mode | [13C]-LYSINE | 244329 | Peak area | SUDHL-1 | Media | CEP-26939 |
| LC/MS positive ion mode | [13C]-LYSINE | 245955 | Peak area | SUDHL-1 | Media | DMSO |
| LC/MS positive ion mode | [13C]-LYSINE | 246039 | Peak area | SUPM2 | Media | DMSO |
| LC/MS positive ion mode | [13C]-LYSINE | 246522 | Peak area | SUDHL-1 | Media | CEP-26939 |
| LC/MS positive ion mode | [13C]-LYSINE | 247536 | Peak area | 293T | Media | K210R NPM-ALK tf |
| LC/MS positive ion mode | [13C]-LYSINE | 249222 | Peak area | 293T | Media | No transfection |
| LC/MS positive ion mode | [13C]-LYSINE | 251874 | Peak area | SUPM2 | Media | DMSO |
| LC/MS positive ion mode | [13C]-LYSINE | 251887 | Peak area | SUPM2 | Media | CEP-26939 |
| LC/MS positive ion mode | [13C]-LYSINE | 254751 | Peak area | SUPM2 | Media | DMSO |
| LC/MS positive ion mode | [13C]-LYSINE | 263729 | Peak area | SR786 | Media | DMSO |
| LC/MS positive ion mode | [13C]-LYSINE | 306007 | Peak area | 293T | Cells | No transfection |
| LC/MS positive ion mode | [13C]-LYSINE | 311873 | Peak area | 293T | Cells | WT NPM-ALK tf |
| LC/MS positive ion mode | [13C]-LYSINE | 314369 | Peak area | 293T | Cells | No transfection |
| LC/MS positive ion mode | [13C]-LYSINE | 329575 | Peak area | 293T | Cells | WT NPM-ALK tf |
| LC/MS positive ion mode | [13C]-LYSINE | 333802 | Peak area | 293T | Cells | K210R NPM-ALK tf |
| LC/MS positive ion mode | [13C]-LYSINE | 334249 | Peak area | 293T | Cells | No transfection |
| LC/MS positive ion mode | [13C]-LYSINE | 336929 | Peak area | 293T | Cells | WT NPM-ALK tf |
| LC/MS positive ion mode | [13C]-LYSINE | 337248 | Peak area | 293T | Cells | No transfection |
| LC/MS positive ion mode | [13C]-LYSINE | 347243 | Peak area | DEL | Cells | DMSO |
| LC/MS positive ion mode | [13C]-LYSINE | 347244 | Peak area | 293T | Cells | K210R NPM-ALK tf |
| LC/MS positive ion mode | [13C]-LYSINE | 348415 | Peak area | 293T | Cells | No transfection |
| LC/MS positive ion mode | [13C]-LYSINE | 350128 | Peak area | 293T | Cells | K210R NPM-ALK tf |
| LC/MS positive ion mode | [13C]-LYSINE | 351993 | Peak area | 293T | Cells | WT NPM-ALK tf |
| LC/MS positive ion mode | [13C]-LYSINE | 358332 | Peak area | 293T | Cells | WT NPM-ALK tf |
| LC/MS positive ion mode | [13C]-LYSINE | 360549 | Peak area | 293T | Cells | K210R NPM-ALK tf |
| LC/MS positive ion mode | [13C]-LYSINE | 376639 | Peak area | 293T | Cells | K210R NPM-ALK tf |
| LC/MS positive ion mode | [13C]-LYSINE | 390127 | Peak area | DEL | Cells | CEP-26939 |
| LC/MS positive ion mode | [13C]-LYSINE | 391598 | Peak area | DEL | Cells | CEP-26939 |
| LC/MS positive ion mode | [13C]-LYSINE | 392781 | Peak area | SR786 | Cells | CEP-26939 |
| LC/MS positive ion mode | [13C]-LYSINE | 393809 | Peak area | DEL | Cells | CEP-26939 |
| LC/MS positive ion mode | [13C]-LYSINE | 404858 | Peak area | SR786 | Cells | CEP-26939 |
| LC/MS positive ion mode | [13C]-LYSINE | 405823 | Peak area | SR786 | Cells | CEP-26939 |
| LC/MS positive ion mode | [13C]-LYSINE | 417966 | Peak area | SR786 | Cells | DMSO |
| LC/MS positive ion mode | [13C]-LYSINE | 441570 | Peak area | SR786 | Cells | DMSO |
| LC/MS positive ion mode | [13C]-LYSINE | 444116 | Peak area | DEL | Cells | CEP-26939 |
| LC/MS positive ion mode | [13C]-LYSINE | 446482 | Peak area | DEL | Cells | CEP-26939 |
| LC/MS positive ion mode | [13C]-LYSINE | 448378 | Peak area | SR786 | Cells | CEP-26939 |
| LC/MS positive ion mode | [13C]-LYSINE | 453011 | Peak area | DEL | Cells | DMSO |
| LC/MS positive ion mode | [13C]-LYSINE | 467574 | Peak area | SR786 | Cells | CEP-26939 |
| LC/MS positive ion mode | [13C]-LYSINE | 468810 | Peak area | SUPM2 | Cells | CEP-26939 |
| LC/MS positive ion mode | [13C]-LYSINE | 476515 | Peak area | SR786 | Cells | DMSO |
| LC/MS positive ion mode | [13C]-LYSINE | 478499 | Peak area | SR786 | Cells | DMSO |
| LC/MS positive ion mode | [13C]-LYSINE | 481409 | Peak area | DEL | Cells | DMSO |
| LC/MS positive ion mode | [13C]-LYSINE | 495675 | Peak area | SUPM2 | Cells | CEP-26939 |
| LC/MS positive ion mode | [13C]-LYSINE | 496298 | Peak area | SUPM2 | Cells | CEP-26939 |
| LC/MS positive ion mode | [13C]-LYSINE | 511272 | Peak area | DEL | Cells | DMSO |
| LC/MS positive ion mode | [13C]-LYSINE | 518576 | Peak area | SUPM2 | Cells | DMSO |
| LC/MS positive ion mode | [13C]-LYSINE | 524355 | Peak area | SUPM2 | Cells | DMSO |
| LC/MS positive ion mode | [13C]-LYSINE | 525653 | Peak area | SR786 | Cells | DMSO |
| LC/MS positive ion mode | [13C]-LYSINE | 536640 | Peak area | SUPM2 | Cells | DMSO |
| LC/MS positive ion mode | [13C]-LYSINE | 549331 | Peak area | SUPM2 | Cells | DMSO |
| LC/MS positive ion mode | [13C]-LYSINE | 562904 | Peak area | SUPM2 | Cells | CEP-26939 |
| LC/MS positive ion mode | [13C]-LYSINE | 577691 | Peak area | SUPM2 | Cells | CEP-26939 |
| LC/MS positive ion mode | [13C]-LYSINE | 585741 | Peak area | SUDHL-1 | Cells | DMSO |
| LC/MS positive ion mode | [13C]-LYSINE | 605619 | Peak area | SUDHL-1 | Cells | CEP-26939 |
| LC/MS positive ion mode | [13C]-LYSINE | 608957 | Peak area | SUPM2 | Cells | DMSO |
| LC/MS positive ion mode | [13C]-LYSINE | 626751 | Peak area | SUDHL-1 | Cells | CEP-26939 |
| LC/MS positive ion mode | [13C]-LYSINE | 640853 | Peak area | SUDHL-1 | Cells | CEP-26939 |
| LC/MS positive ion mode | [13C]-LYSINE | 652421 | Peak area | SUDHL-1 | Cells | DMSO |
| LC/MS positive ion mode | [13C]-LYSINE | 661744 | Peak area | DEL | Cells | DMSO |
| LC/MS positive ion mode | [13C]-LYSINE | 666057 | Peak area | SUDHL-1 | Cells | DMSO |
| LC/MS positive ion mode | [13C]-LYSINE | 674640 | Peak area | SUDHL-1 | Cells | DMSO |
| LC/MS positive ion mode | [13C]-LYSINE | 680779 | Peak area | SUDHL-1 | Cells | CEP-26939 |
| LC/MS positive ion mode | [13C]-LYSINE | 688465 | Peak area | SUDHL-1 | Cells | DMSO |
| LC/MS positive ion mode | [13C]-LYSINE | 951431 | Peak area | SUDHL-1 | Cells | CEP-26939 |
| LC/MS positive ion mode | LYSINE | 422701 | Peak area | 293T | Media | K210R NPM-ALK tf |
| LC/MS positive ion mode | LYSINE | 425159 | Peak area | 293T | Cells | K210R NPM-ALK tf |
| LC/MS positive ion mode | LYSINE | 425370 | Peak area | 293T | Cells | No transfection |
| LC/MS positive ion mode | LYSINE | 447764 | Peak area | 293T | Cells | WT NPM-ALK tf |
| LC/MS positive ion mode | LYSINE | 448213 | Peak area | 293T | Cells | WT NPM-ALK tf |
| LC/MS positive ion mode | LYSINE | 461786 | Peak area | DEL | Cells | DMSO |
| LC/MS positive ion mode | LYSINE | 461863 | Peak area | 293T | Cells | K210R NPM-ALK tf |
| LC/MS positive ion mode | LYSINE | 466799 | Peak area | 293T | Cells | WT NPM-ALK tf |
| LC/MS positive ion mode | LYSINE | 467310 | Peak area | 293T | Cells | No transfection |
| LC/MS positive ion mode | LYSINE | 469184 | Peak area | 293T | Cells | No transfection |
| LC/MS positive ion mode | LYSINE | 470164 | Peak area | SUPM2 | Cells | CEP-26939 |
| LC/MS positive ion mode | LYSINE | 475013 | Peak area | SUPM2 | Cells | CEP-26939 |
| LC/MS positive ion mode | LYSINE | 475322 | Peak area | SUPM2 | Cells | DMSO |
| LC/MS positive ion mode | LYSINE | 480201 | Peak area | 293T | Cells | K210R NPM-ALK tf |
| LC/MS positive ion mode | LYSINE | 494712 | Peak area | 293T | Cells | K210R NPM-ALK tf |
| LC/MS positive ion mode | LYSINE | 498347 | Peak area | SUPM2 | Cells | DMSO |
| LC/MS positive ion mode | LYSINE | 518090 | Peak area | 293T | Cells | WT NPM-ALK tf |
| LC/MS positive ion mode | LYSINE | 529039 | Peak area | 293T | Cells | WT NPM-ALK tf |
| LC/MS positive ion mode | LYSINE | 530744 | Peak area | SUPM2 | Cells | CEP-26939 |
| LC/MS positive ion mode | LYSINE | 532675 | Peak area | SUPM2 | Cells | DMSO |
| LC/MS positive ion mode | LYSINE | 538152 | Peak area | 293T | Cells | K210R NPM-ALK tf |
| LC/MS positive ion mode | LYSINE | 544499 | Peak area | SUPM2 | Cells | DMSO |
| LC/MS positive ion mode | LYSINE | 547178 | Peak area | 293T | Media | No transfection |
| LC/MS positive ion mode | LYSINE | 548468 | Peak area | SUPM2 | Cells | DMSO |
| LC/MS positive ion mode | LYSINE | 555367 | Peak area | SUPM2 | Cells | CEP-26939 |
| LC/MS positive ion mode | LYSINE | 556398 | Peak area | SUPM2 | Cells | CEP-26939 |
| LC/MS positive ion mode | LYSINE | 559022 | Peak area | 293T | Cells | No transfection |
| LC/MS positive ion mode | LYSINE | 570713 | Peak area | DEL | Cells | DMSO |
| LC/MS positive ion mode | LYSINE | 578314 | Peak area | DEL | Cells | DMSO |
| LC/MS positive ion mode | LYSINE | 579578 | Peak area | DEL | Cells | DMSO |
| LC/MS positive ion mode | LYSINE | 610958 | Peak area | 293T | Cells | No transfection |
| LC/MS positive ion mode | LYSINE | 617455 | Peak area | DEL | Cells | DMSO |
| LC/MS positive ion mode | LYSINE | 648647 | Peak area | 293T | Media | No transfection |
| LC/MS positive ion mode | LYSINE | 658060 | Peak area | DEL | Cells | CEP-26939 |
| LC/MS positive ion mode | LYSINE | 658082 | Peak area | 293T | Media | No transfection |
| LC/MS positive ion mode | LYSINE | 678295 | Peak area | DEL | Cells | CEP-26939 |
| LC/MS positive ion mode | LYSINE | 692254 | Peak area | 293T | Media | No transfection |
| LC/MS positive ion mode | LYSINE | 697096 | Peak area | SUDHL-1 | Cells | DMSO |
| LC/MS positive ion mode | LYSINE | 706947 | Peak area | DEL | Cells | CEP-26939 |
| LC/MS positive ion mode | LYSINE | 723987 | Peak area | DEL | Cells | CEP-26939 |
| LC/MS positive ion mode | LYSINE | 739638 | Peak area | 293T | Media | WT NPM-ALK tf |
| LC/MS positive ion mode | LYSINE | 742748 | Peak area | 293T | Media | WT NPM-ALK tf |
| LC/MS positive ion mode | LYSINE | 770974 | Peak area | 293T | Media | No transfection |
| LC/MS positive ion mode | LYSINE | 786945 | Peak area | 293T | Media | K210R NPM-ALK tf |
| LC/MS positive ion mode | LYSINE | 793486 | Peak area | 293T | Media | K210R NPM-ALK tf |
| LC/MS positive ion mode | LYSINE | 814648 | Peak area | DEL | Cells | CEP-26939 |
| LC/MS positive ion mode | LYSINE | 817265 | Peak area | SUDHL-1 | Cells | DMSO |
| LC/MS positive ion mode | LYSINE | 828554 | Peak area | 293T | Media | WT NPM-ALK tf |
| LC/MS positive ion mode | LYSINE | 829844 | Peak area | SUDHL-1 | Cells | CEP-26939 |
| LC/MS positive ion mode | LYSINE | 846676 | Peak area | 293T | Media | WT NPM-ALK tf |
| LC/MS positive ion mode | LYSINE | 861002 | Peak area | 293T | Media | K210R NPM-ALK tf |
| LC/MS positive ion mode | LYSINE | 866063 | Peak area | 293T | Media | WT NPM-ALK tf |
| LC/MS positive ion mode | LYSINE | 871905 | Peak area | SUDHL-1 | Cells | DMSO |
| LC/MS positive ion mode | LYSINE | 875444 | Peak area | 293T | Media | K210R NPM-ALK tf |
| LC/MS positive ion mode | LYSINE | 990302 | Peak area | SUDHL-1 | Cells | DMSO |
| LC/MS positive ion mode | LYSINE | 1000197 | Peak area | SUDHL-1 | Cells | CEP-26939 |
| LC/MS positive ion mode | LYSINE | 1046607 | Peak area | DEL | Media | CEP-26939 |
| LC/MS positive ion mode | LYSINE | 1056944 | Peak area | SUDHL-1 | Cells | CEP-26939 |
| LC/MS positive ion mode | LYSINE | 1089567 | Peak area | DEL | Media | CEP-26939 |
| LC/MS positive ion mode | LYSINE | 1158447 | Peak area | DEL | Media | DMSO |
| LC/MS positive ion mode | LYSINE | 1172060 | Peak area | DEL | Media | DMSO |
| LC/MS positive ion mode | LYSINE | 1186306 | Peak area | SR786 | Media | CEP-26939 |
| LC/MS positive ion mode | LYSINE | 1231698 | Peak area | SUDHL-1 | Cells | CEP-26939 |
| LC/MS positive ion mode | LYSINE | 1243603 | Peak area | SUDHL-1 | Media | DMSO |
| LC/MS positive ion mode | LYSINE | 1250348 | Peak area | SUDHL-1 | Media | DMSO |
| LC/MS positive ion mode | LYSINE | 1263396 | Peak area | SR786 | Media | CEP-26939 |
| LC/MS positive ion mode | LYSINE | 1276073 | Peak area | SR786 | Media | DMSO |
| LC/MS positive ion mode | LYSINE | 1283920 | Peak area | DEL | Media | CEP-26939 |
| LC/MS positive ion mode | LYSINE | 1299210 | Peak area | SUDHL-1 | Media | DMSO |
| LC/MS positive ion mode | LYSINE | 1301754 | Peak area | SR786 | Media | DMSO |
| LC/MS positive ion mode | LYSINE | 1311558 | Peak area | DEL | Media | CEP-26939 |
| LC/MS positive ion mode | LYSINE | 1322821 | Peak area | DEL | Media | DMSO |
| LC/MS positive ion mode | LYSINE | 1334693 | Peak area | SUDHL-1 | Cells | DMSO |
| LC/MS positive ion mode | LYSINE | 1334779 | Peak area | DEL | Media | DMSO |
| LC/MS positive ion mode | LYSINE | 1337143 | Peak area | DEL | Media | CEP-26939 |
| LC/MS positive ion mode | LYSINE | 1346710 | Peak area | SUPM2 | Media | CEP-26939 |
| LC/MS positive ion mode | LYSINE | 1346998 | Peak area | DEL | Media | DMSO |
| LC/MS positive ion mode | LYSINE | 1350467 | Peak area | SUDHL-1 | Media | CEP-26939 |
| LC/MS positive ion mode | LYSINE | 1356294 | Peak area | SUPM2 | Media | DMSO |
| LC/MS positive ion mode | LYSINE | 1359323 | Peak area | SR786 | Media | DMSO |
| LC/MS positive ion mode | LYSINE | 1362200 | Peak area | SUDHL-1 | Media | CEP-26939 |
| LC/MS positive ion mode | LYSINE | 1381719 | Peak area | SUDHL-1 | Media | DMSO |
| LC/MS positive ion mode | LYSINE | 1392166 | Peak area | SR786 | Media | DMSO |
| LC/MS positive ion mode | LYSINE | 1400354 | Peak area | SUDHL-1 | Media | CEP-26939 |
| LC/MS positive ion mode | LYSINE | 1409061 | Peak area | SUPM2 | Media | DMSO |
| LC/MS positive ion mode | LYSINE | 1416396 | Peak area | SR786 | Media | CEP-26939 |
| LC/MS positive ion mode | LYSINE | 1423120 | Peak area | SUDHL-1 | Media | DMSO |
| LC/MS positive ion mode | LYSINE | 1427216 | Peak area | SUPM2 | Media | DMSO |
| LC/MS positive ion mode | LYSINE | 1433746 | Peak area | SR786 | Media | CEP-26939 |
| LC/MS positive ion mode | LYSINE | 1436582 | Peak area | SUPM2 | Media | CEP-26939 |
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