| Analysis | Metabolite Name | Measured Value | Units | Group | TIMEPOINT |
|---|---|---|---|---|---|
| Reversed phase POSITIVE ION MODE | leucine | 0.4662 | scaled units | High-Dose | +4HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.4963 | scaled units | Placebo | -0.5HR |
| Reversed phase POSITIVE ION MODE | leucine | 0.5158 | scaled units | Placebo | +4HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.5324 | scaled units | High-Dose | +71HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.5373 | scaled units | High-Dose | +4HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.5480 | scaled units | Low-Dose | +4HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.5511 | scaled units | High-Dose | +47HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.5636 | scaled units | High-Dose | +4HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.5671 | scaled units | High-Dose | +4HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.5703 | scaled units | Placebo | +23HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.5730 | scaled units | High-Dose | +71HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.5910 | scaled units | High-Dose | +71HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.5911 | scaled units | High-Dose | +4HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.5984 | scaled units | Placebo | +71HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.6195 | scaled units | High-Dose | +4HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.6202 | scaled units | High-Dose | +4HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.6346 | scaled units | Placebo | BASELINE |
| Reversed phase POSITIVE ION MODE | leucine | 0.6517 | scaled units | Low-Dose | +4HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.6550 | scaled units | High-Dose | +71HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.6605 | scaled units | Low-Dose | +71HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.6624 | scaled units | Low-Dose | +4HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.6663 | scaled units | High-Dose | +4HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.6680 | scaled units | High-Dose | +47HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.6789 | scaled units | High-Dose | +47HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.6838 | scaled units | High-Dose | +47HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.6918 | scaled units | High-Dose | +47HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.7080 | scaled units | High-Dose | +71HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.7127 | scaled units | Low-Dose | +4HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.7260 | scaled units | Low-Dose | +4HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.7349 | scaled units | High-Dose | +71HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.7390 | scaled units | Low-Dose | +23HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.7516 | scaled units | Low-Dose | +4HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.7541 | scaled units | High-Dose | +4HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.7592 | scaled units | Low-Dose | +71HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.7725 | scaled units | High-Dose | +23HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.7818 | scaled units | Placebo | +4HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.7984 | scaled units | Low-Dose | +4HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.8022 | scaled units | High-Dose | +4HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.8040 | scaled units | High-Dose | BASELINE |
| Reversed phase POSITIVE ION MODE | leucine | 0.8049 | scaled units | Low-Dose | +23HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.8058 | scaled units | Low-Dose | +4HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.8084 | scaled units | High-Dose | +71HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.8105 | scaled units | High-Dose | +23HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.8127 | scaled units | Placebo | +4HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.8140 | scaled units | Low-Dose | +47HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.8241 | scaled units | Low-Dose | +23HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.8256 | scaled units | High-Dose | +47HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.8266 | scaled units | Low-Dose | BASELINE |
| Reversed phase POSITIVE ION MODE | leucine | 0.8269 | scaled units | High-Dose | +47HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.8299 | scaled units | High-Dose | +23HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.8324 | scaled units | Low-Dose | BASELINE |
| Reversed phase POSITIVE ION MODE | leucine | 0.8437 | scaled units | Low-Dose | +71HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.8478 | scaled units | High-Dose | -0.5HR |
| Reversed phase POSITIVE ION MODE | leucine | 0.8505 | scaled units | Placebo | BASELINE |
| Reversed phase POSITIVE ION MODE | leucine | 0.8509 | scaled units | Low-Dose | +4HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.8522 | scaled units | Low-Dose | -0.5HR |
| Reversed phase POSITIVE ION MODE | leucine | 0.8523 | scaled units | High-Dose | +23HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.8596 | scaled units | Low-Dose | -0.5HR |
| Reversed phase POSITIVE ION MODE | leucine | 0.8619 | scaled units | High-Dose | +71HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.8624 | scaled units | Low-Dose | +47HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.8626 | scaled units | Low-Dose | +23HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.8638 | scaled units | Low-Dose | +71HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.8698 | scaled units | Low-Dose | +23HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.8803 | scaled units | Low-Dose | +47HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.8938 | scaled units | Placebo | BASELINE |
| Reversed phase POSITIVE ION MODE | leucine | 0.8942 | scaled units | Placebo | +47HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.8948 | scaled units | High-Dose | +23HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.8968 | scaled units | High-Dose | +4HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.9094 | scaled units | Placebo | -0.5HR |
| Reversed phase POSITIVE ION MODE | leucine | 0.9106 | scaled units | Low-Dose | +23HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.9134 | scaled units | Low-Dose | +47HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.9199 | scaled units | Low-Dose | +71HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.9202 | scaled units | Low-Dose | +4HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.9322 | scaled units | Low-Dose | +23HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.9444 | scaled units | Placebo | +4HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.9472 | scaled units | High-Dose | BASELINE |
| Reversed phase POSITIVE ION MODE | leucine | 0.9508 | scaled units | Low-Dose | +23HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.9527 | scaled units | High-Dose | -0.5HR |
| Reversed phase POSITIVE ION MODE | leucine | 0.9575 | scaled units | Low-Dose | BASELINE |
| Reversed phase POSITIVE ION MODE | leucine | 0.9597 | scaled units | Placebo | +71HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.9621 | scaled units | High-Dose | -0.5HR |
| Reversed phase POSITIVE ION MODE | leucine | 0.9681 | scaled units | Low-Dose | +47HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.9762 | scaled units | High-Dose | -0.5HR |
| Reversed phase POSITIVE ION MODE | leucine | 0.9770 | scaled units | High-Dose | BASELINE |
| Reversed phase POSITIVE ION MODE | leucine | 0.9849 | scaled units | Low-Dose | -0.5HR |
| Reversed phase POSITIVE ION MODE | leucine | 0.9850 | scaled units | Low-Dose | +47HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.9858 | scaled units | Low-Dose | BASELINE |
| Reversed phase POSITIVE ION MODE | leucine | 0.9889 | scaled units | High-Dose | +23HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.9889 | scaled units | Low-Dose | +23HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.9964 | scaled units | Low-Dose | +23HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 0.9967 | scaled units | High-Dose | BASELINE |
| Reversed phase POSITIVE ION MODE | leucine | 0.9997 | scaled units | Placebo | +47HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.0000 | scaled units | High-Dose | BASELINE |
| Reversed phase POSITIVE ION MODE | leucine | 1.0003 | scaled units | High-Dose | +23HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.0046 | scaled units | High-Dose | +47HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.0046 | scaled units | Low-Dose | +71HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.0063 | scaled units | High-Dose | -0.5HR |
| Reversed phase POSITIVE ION MODE | leucine | 1.0074 | scaled units | Low-Dose | -0.5HR |
| Reversed phase POSITIVE ION MODE | leucine | 1.0088 | scaled units | Placebo | -0.5HR |
| Reversed phase POSITIVE ION MODE | leucine | 1.0131 | scaled units | Low-Dose | BASELINE |
| Reversed phase POSITIVE ION MODE | leucine | 1.0192 | scaled units | Low-Dose | +47HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.0197 | scaled units | High-Dose | BASELINE |
| Reversed phase POSITIVE ION MODE | leucine | 1.0228 | scaled units | Placebo | +23HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.0229 | scaled units | Placebo | +71HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.0242 | scaled units | Low-Dose | +71HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.0329 | scaled units | Placebo | -0.5HR |
| Reversed phase POSITIVE ION MODE | leucine | 1.0339 | scaled units | Low-Dose | +71HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.0354 | scaled units | High-Dose | +23HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.0367 | scaled units | High-Dose | BASELINE |
| Reversed phase POSITIVE ION MODE | leucine | 1.0371 | scaled units | High-Dose | +47HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.0396 | scaled units | Placebo | -0.5HR |
| Reversed phase POSITIVE ION MODE | leucine | 1.0420 | scaled units | Low-Dose | -0.5HR |
| Reversed phase POSITIVE ION MODE | leucine | 1.0429 | scaled units | Low-Dose | BASELINE |
| Reversed phase POSITIVE ION MODE | leucine | 1.0487 | scaled units | Placebo | +47HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.0506 | scaled units | Low-Dose | BASELINE |
| Reversed phase POSITIVE ION MODE | leucine | 1.0527 | scaled units | Low-Dose | -0.5HR |
| Reversed phase POSITIVE ION MODE | leucine | 1.0554 | scaled units | High-Dose | BASELINE |
| Reversed phase POSITIVE ION MODE | leucine | 1.0609 | scaled units | Placebo | +71HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.0638 | scaled units | Placebo | +71HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.0644 | scaled units | High-Dose | -0.5HR |
| Reversed phase POSITIVE ION MODE | leucine | 1.0679 | scaled units | Low-Dose | -0.5HR |
| Reversed phase POSITIVE ION MODE | leucine | 1.0765 | scaled units | High-Dose | +47HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.0786 | scaled units | Low-Dose | BASELINE |
| Reversed phase POSITIVE ION MODE | leucine | 1.0817 | scaled units | High-Dose | +23HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.0845 | scaled units | Low-Dose | +71HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.0857 | scaled units | Placebo | +47HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.0890 | scaled units | Placebo | +47HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.0973 | scaled units | Low-Dose | -0.5HR |
| Reversed phase POSITIVE ION MODE | leucine | 1.0986 | scaled units | Placebo | BASELINE |
| Reversed phase POSITIVE ION MODE | leucine | 1.1025 | scaled units | Placebo | +47HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.1033 | scaled units | Placebo | BASELINE |
| Reversed phase POSITIVE ION MODE | leucine | 1.1048 | scaled units | High-Dose | +71HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.1054 | scaled units | Placebo | -0.5HR |
| Reversed phase POSITIVE ION MODE | leucine | 1.1072 | scaled units | Low-Dose | +23HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.1075 | scaled units | High-Dose | +71HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.1131 | scaled units | Placebo | +71HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.1132 | scaled units | Low-Dose | -0.5HR |
| Reversed phase POSITIVE ION MODE | leucine | 1.1150 | scaled units | Low-Dose | BASELINE |
| Reversed phase POSITIVE ION MODE | leucine | 1.1155 | scaled units | High-Dose | -0.5HR |
| Reversed phase POSITIVE ION MODE | leucine | 1.1210 | scaled units | Placebo | +4HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.1217 | scaled units | High-Dose | BASELINE |
| Reversed phase POSITIVE ION MODE | leucine | 1.1257 | scaled units | Placebo | +23HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.1284 | scaled units | Low-Dose | -0.5HR |
| Reversed phase POSITIVE ION MODE | leucine | 1.1311 | scaled units | Low-Dose | -0.5HR |
| Reversed phase POSITIVE ION MODE | leucine | 1.1389 | scaled units | Low-Dose | +71HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.1394 | scaled units | Placebo | +71HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.1445 | scaled units | Placebo | +23HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.1464 | scaled units | Placebo | BASELINE |
| Reversed phase POSITIVE ION MODE | leucine | 1.1528 | scaled units | Low-Dose | +23HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.1608 | scaled units | Placebo | -0.5HR |
| Reversed phase POSITIVE ION MODE | leucine | 1.1626 | scaled units | Low-Dose | +47HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.1635 | scaled units | Placebo | +23HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.1679 | scaled units | Placebo | -0.5HR |
| Reversed phase POSITIVE ION MODE | leucine | 1.1712 | scaled units | Placebo | +47HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.1751 | scaled units | High-Dose | -0.5HR |
| Reversed phase POSITIVE ION MODE | leucine | 1.1786 | scaled units | Placebo | +4HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.1815 | scaled units | Low-Dose | +47HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.1857 | scaled units | High-Dose | -0.5HR |
| Reversed phase POSITIVE ION MODE | leucine | 1.1922 | scaled units | Low-Dose | +47HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.2006 | scaled units | High-Dose | BASELINE |
| Reversed phase POSITIVE ION MODE | leucine | 1.2188 | scaled units | Low-Dose | +71HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.2320 | scaled units | High-Dose | +23HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.2408 | scaled units | Placebo | +47HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.2472 | scaled units | Placebo | +23HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.2623 | scaled units | Low-Dose | -0.5HR |
| Reversed phase POSITIVE ION MODE | leucine | 1.2638 | scaled units | Low-Dose | +47HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.2707 | scaled units | Placebo | BASELINE |
| Reversed phase POSITIVE ION MODE | leucine | 1.2764 | scaled units | Placebo | +71HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.2778 | scaled units | Low-Dose | BASELINE |
| Reversed phase POSITIVE ION MODE | leucine | 1.2821 | scaled units | Placebo | +4HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.2859 | scaled units | Placebo | +4HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.2951 | scaled units | Placebo | +4HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.3179 | scaled units | Placebo | +4HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.3221 | scaled units | Placebo | +23HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.3372 | scaled units | Low-Dose | BASELINE |
| Reversed phase POSITIVE ION MODE | leucine | 1.3585 | scaled units | Placebo | BASELINE |
| Reversed phase POSITIVE ION MODE | leucine | 1.3667 | scaled units | High-Dose | -0.5HR |
| Reversed phase POSITIVE ION MODE | leucine | 1.3718 | scaled units | High-Dose | BASELINE |
| Reversed phase POSITIVE ION MODE | leucine | 1.3749 | scaled units | Placebo | BASELINE |
| Reversed phase POSITIVE ION MODE | leucine | 1.4030 | scaled units | Placebo | +71HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.4108 | scaled units | Placebo | -0.5HR |
| Reversed phase POSITIVE ION MODE | leucine | 1.4241 | scaled units | Placebo | +47HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.4369 | scaled units | Placebo | +71HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.5201 | scaled units | Placebo | +23HR POST INFUSION |
| Reversed phase POSITIVE ION MODE | leucine | 1.5351 | scaled units | Placebo | BASELINE |
| Reversed phase POSITIVE ION MODE | leucine | 1.5518 | scaled units | Placebo | -0.5HR |
- UCSD Metabolomics Workbench, a resource sponsored by the Common Fund of the National Institutes of Health
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