Analysis Metabolite Name Measured Value Units Drug Pre vs. Post
ESI positive ion mode1-Methylhistidine0.491821425uMPlacebo Post
ESI positive ion mode1-Methylhistidine0.531045614uMPlacebo Pre
ESI positive ion mode1-Methylhistidine0.600545627uMPlacebo Pre
ESI positive ion mode1-Methylhistidine0.625076301uMPlacebo Post
ESI positive ion mode1-Methylhistidine0.631850867uMPlacebo Post
ESI positive ion mode1-Methylhistidine0.651003461uMPlacebo Post
ESI positive ion mode1-Methylhistidine0.749116327uMPlacebo Pre
ESI positive ion mode1-Methylhistidine0.765050157uMPlacebo Pre
ESI positive ion mode1-Methylhistidine2.059055822uMPlacebo Pre
ESI positive ion mode1-Methylhistidine2.430660606uMMetformin Pre
ESI positive ion mode1-Methylhistidine2.574102265uMPlacebo Post
ESI positive ion mode1-Methylhistidine2.601011582uMPlacebo Post
ESI positive ion mode1-Methylhistidine2.764049689uMPlacebo Pre
ESI positive ion mode1-Methylhistidine2.81223782uMPlacebo Pre
ESI positive ion mode1-Methylhistidine2.825683803uMMetformin Pre
ESI positive ion mode1-Methylhistidine2.934131975uMPlacebo Post
ESI positive ion mode1-Methylhistidine3.000117033uMMetformin Post
ESI positive ion mode1-Methylhistidine3.033952508uMPlacebo Post
ESI positive ion mode1-Methylhistidine3.061863326uMPlacebo Pre
ESI positive ion mode1-Methylhistidine3.124042716uMMetformin Post
ESI positive ion mode1-Methylhistidine3.199492179uMMetformin Pre
ESI positive ion mode1-Methylhistidine3.271434859uMMetformin Post
ESI positive ion mode1-Methylhistidine3.272406758uMPlacebo Post
ESI positive ion mode1-Methylhistidine3.288118932uMMetformin Pre
ESI positive ion mode1-Methylhistidine3.307909703uMMetformin Pre
ESI positive ion mode1-Methylhistidine3.415791507uMMetformin Pre
ESI positive ion mode1-Methylhistidine3.433957036uMMetformin Post
ESI positive ion mode1-Methylhistidine3.446449253uMMetformin Post
ESI positive ion mode1-Methylhistidine3.461316048uMMetformin Post
ESI positive ion mode1-Methylhistidine3.493886809uMMetformin Post
ESI positive ion mode1-Methylhistidine3.596086643uMMetformin Post
ESI positive ion mode1-Methylhistidine3.609339751uMMetformin Post
ESI positive ion mode1-Methylhistidine3.687019846uMPlacebo Post
ESI positive ion mode1-Methylhistidine3.753519393uMPlacebo Post
ESI positive ion mode1-Methylhistidine3.805530547uMMetformin Pre
ESI positive ion mode1-Methylhistidine4.099056199uMMetformin Post
ESI positive ion mode1-Methylhistidine4.134023377uMPlacebo Pre
ESI positive ion mode1-Methylhistidine4.1541356uMPlacebo Post
ESI positive ion mode1-Methylhistidine4.183972454uMPlacebo Pre
ESI positive ion mode1-Methylhistidine4.384636184uMMetformin Pre
ESI positive ion mode1-Methylhistidine4.445088636uMPlacebo Pre
ESI positive ion mode1-Methylhistidine4.520704157uMPlacebo Pre
ESI positive ion mode1-Methylhistidine4.618184889uMMetformin Post
ESI positive ion mode1-Methylhistidine4.64356578uMMetformin Post
ESI positive ion mode1-Methylhistidine4.842878429uMMetformin Post
ESI positive ion mode1-Methylhistidine4.912160908uMPlacebo Pre
ESI positive ion mode1-Methylhistidine5.080041924uMMetformin Pre
ESI positive ion mode1-Methylhistidine5.206389333uMPlacebo Pre
ESI positive ion mode1-Methylhistidine5.303027898uMPlacebo Pre
ESI positive ion mode1-Methylhistidine5.351181519uMMetformin Pre
ESI positive ion mode1-Methylhistidine5.357140924uMPlacebo Post
ESI positive ion mode1-Methylhistidine5.386785643uMMetformin Pre
ESI positive ion mode1-Methylhistidine5.420034099uMMetformin Pre
ESI positive ion mode1-Methylhistidine5.517216955uMMetformin Post
ESI positive ion mode1-Methylhistidine5.558709558uMMetformin Pre
ESI positive ion mode1-Methylhistidine5.582189046uMMetformin Pre
ESI positive ion mode1-Methylhistidine5.637665469uMPlacebo Pre
ESI positive ion mode1-Methylhistidine5.657085858uMPlacebo Pre
ESI positive ion mode1-Methylhistidine5.687139456uMMetformin Post
ESI positive ion mode1-Methylhistidine5.691840179uMMetformin Pre
ESI positive ion mode1-Methylhistidine5.691955998uMMetformin Pre
ESI positive ion mode1-Methylhistidine5.694864166uMMetformin Pre
ESI positive ion mode1-Methylhistidine5.711934725uMMetformin Post
ESI positive ion mode1-Methylhistidine5.717172056uMMetformin Pre
ESI positive ion mode1-Methylhistidine5.791813346uMPlacebo Post
ESI positive ion mode1-Methylhistidine5.899107001uMPlacebo Post
ESI positive ion mode1-Methylhistidine5.93258039uMPlacebo Post
ESI positive ion mode1-Methylhistidine5.969995309uMMetformin Pre
ESI positive ion mode1-Methylhistidine6.118488584uMPlacebo Pre
ESI positive ion mode1-Methylhistidine6.202843801uMMetformin Post
ESI positive ion mode1-Methylhistidine6.209678217uMMetformin Post
ESI positive ion mode1-Methylhistidine6.229181803uMPlacebo Post
ESI positive ion mode1-Methylhistidine6.233226628uMMetformin Post
ESI positive ion mode1-Methylhistidine6.319847885uMPlacebo Post
ESI positive ion mode1-Methylhistidine6.326901434uMMetformin Pre
ESI positive ion mode1-Methylhistidine6.35160674uMPlacebo Post
ESI positive ion mode1-Methylhistidine6.407146548uMMetformin Post
ESI positive ion mode1-Methylhistidine6.454824104uMMetformin Pre
ESI positive ion mode1-Methylhistidine6.578289391uMPlacebo Pre
ESI positive ion mode1-Methylhistidine6.592692867uMPlacebo Post
ESI positive ion mode1-Methylhistidine6.644488568uMMetformin Post
ESI positive ion mode1-Methylhistidine6.686649962uMMetformin Pre
ESI positive ion mode1-Methylhistidine6.747882445uMMetformin Post
ESI positive ion mode1-Methylhistidine6.760005997uMMetformin Post
ESI positive ion mode1-Methylhistidine6.890028485uMPlacebo Post
ESI positive ion mode1-Methylhistidine7.003162086uMPlacebo Pre
ESI positive ion mode1-Methylhistidine7.027271991uMMetformin Post
ESI positive ion mode1-Methylhistidine7.090562279uMMetformin Pre
ESI positive ion mode1-Methylhistidine7.14320633uMPlacebo Post
ESI positive ion mode1-Methylhistidine7.153132174uMMetformin Post
ESI positive ion mode1-Methylhistidine7.208218604uMMetformin Pre
ESI positive ion mode1-Methylhistidine7.24066249uMMetformin Post
ESI positive ion mode1-Methylhistidine7.334654389uMPlacebo Pre
ESI positive ion mode1-Methylhistidine7.403265034uMMetformin Post
ESI positive ion mode1-Methylhistidine7.417294414uMPlacebo Pre
ESI positive ion mode1-Methylhistidine7.425912734uMPlacebo Post
ESI positive ion mode1-Methylhistidine7.581338827uMPlacebo Pre
ESI positive ion mode1-Methylhistidine7.611944822uMMetformin Pre
ESI positive ion mode1-Methylhistidine7.6174827uMMetformin Post
ESI positive ion mode1-Methylhistidine7.633385569uMMetformin Pre
ESI positive ion mode1-Methylhistidine7.763526246uMMetformin Post
ESI positive ion mode1-Methylhistidine7.983232331uMMetformin Pre
ESI positive ion mode1-Methylhistidine8.015224789uMMetformin Post
ESI positive ion mode1-Methylhistidine8.220103587uMPlacebo Post
ESI positive ion mode1-Methylhistidine8.39818277uMMetformin Post
ESI positive ion mode1-Methylhistidine8.420791878uMMetformin Pre
ESI positive ion mode1-Methylhistidine8.512522992uMMetformin Pre
ESI positive ion mode1-Methylhistidine8.574898466uMPlacebo Post
ESI positive ion mode1-Methylhistidine8.6139105uMMetformin Post
ESI positive ion mode1-Methylhistidine8.654485299uMMetformin Pre
ESI positive ion mode1-Methylhistidine8.847640577uMPlacebo Post
ESI positive ion mode1-Methylhistidine8.852924671uMPlacebo Post
ESI positive ion mode1-Methylhistidine8.949358439uMPlacebo Pre
ESI positive ion mode1-Methylhistidine9.010936037uMMetformin Post
ESI positive ion mode1-Methylhistidine9.083057395uMPlacebo Post
ESI positive ion mode1-Methylhistidine9.258453261uMMetformin Pre
ESI positive ion mode1-Methylhistidine9.286230514uMPlacebo Post
ESI positive ion mode1-Methylhistidine9.536480747uMPlacebo Pre
ESI positive ion mode1-Methylhistidine9.633358176uMMetformin Pre
ESI positive ion mode1-Methylhistidine9.691168322uMMetformin Pre
ESI positive ion mode1-Methylhistidine9.713577226uMMetformin Post
ESI positive ion mode1-Methylhistidine9.72655499uMPlacebo Pre
ESI positive ion mode1-Methylhistidine9.737457206uMMetformin Pre
ESI positive ion mode1-Methylhistidine9.745442531uMMetformin Post
ESI positive ion mode1-Methylhistidine9.754373538uMPlacebo Pre
ESI positive ion mode1-Methylhistidine9.785273475uMMetformin Pre
ESI positive ion mode1-Methylhistidine9.86021857uMPlacebo Pre
ESI positive ion mode1-Methylhistidine10.24287798uMPlacebo Post
ESI positive ion mode1-Methylhistidine10.30908912uMMetformin Pre
ESI positive ion mode1-Methylhistidine10.66657944uMPlacebo Post
ESI positive ion mode1-Methylhistidine10.69060034uMMetformin Pre
ESI positive ion mode1-Methylhistidine10.85343583uMMetformin Post
ESI positive ion mode1-Methylhistidine10.91558595uMPlacebo Pre
ESI positive ion mode1-Methylhistidine10.9503055uMPlacebo Pre
ESI positive ion mode1-Methylhistidine10.9867408uMPlacebo Pre
ESI positive ion mode1-Methylhistidine11.03514569uMMetformin Pre
ESI positive ion mode1-Methylhistidine11.12542094uMMetformin Post
ESI positive ion mode1-Methylhistidine11.23249319uMPlacebo Pre
ESI positive ion mode1-Methylhistidine11.50202913uMPlacebo Post
ESI positive ion mode1-Methylhistidine11.68828412uMPlacebo Pre
ESI positive ion mode1-Methylhistidine11.76805444uMMetformin Post
ESI positive ion mode1-Methylhistidine11.80429858uMPlacebo Pre
ESI positive ion mode1-Methylhistidine11.90522967uMMetformin Post
ESI positive ion mode1-Methylhistidine12.01472682uMMetformin Pre
ESI positive ion mode1-Methylhistidine12.17377927uMMetformin Pre
ESI positive ion mode1-Methylhistidine12.36756023uMMetformin Pre
ESI positive ion mode1-Methylhistidine12.5283661uMMetformin Post
ESI positive ion mode1-Methylhistidine12.70214741uMMetformin Post
ESI positive ion mode1-Methylhistidine12.72978617uMPlacebo Pre
ESI positive ion mode1-Methylhistidine12.83887355uMPlacebo Post
ESI positive ion mode1-Methylhistidine12.9693254uMPlacebo Post
ESI positive ion mode1-Methylhistidine13.11725894uMMetformin Post
ESI positive ion mode1-Methylhistidine13.51735698uMMetformin Pre
ESI positive ion mode1-Methylhistidine13.56362355uMPlacebo Pre
ESI positive ion mode1-Methylhistidine13.68275671uMPlacebo Post
ESI positive ion mode1-Methylhistidine13.92261702uMPlacebo Post
ESI positive ion mode1-Methylhistidine14.22770951uMMetformin Pre
ESI positive ion mode1-Methylhistidine14.53017562uMPlacebo Post
ESI positive ion mode1-Methylhistidine14.87562184uMMetformin Post
ESI positive ion mode1-Methylhistidine14.93330963uMMetformin Pre
ESI positive ion mode1-Methylhistidine14.9502062uMPlacebo Post
ESI positive ion mode1-Methylhistidine14.98640182uMMetformin Pre
ESI positive ion mode1-Methylhistidine15.34953138uMPlacebo Post
ESI positive ion mode1-Methylhistidine15.54578165uMPlacebo Pre
ESI positive ion mode1-Methylhistidine15.59940144uMPlacebo Post
ESI positive ion mode1-Methylhistidine16.01318728uMPlacebo Post
ESI positive ion mode1-Methylhistidine16.20156071uMPlacebo Pre
ESI positive ion mode1-Methylhistidine16.23776097uMPlacebo Post
ESI positive ion mode1-Methylhistidine16.54656451uMMetformin Pre
ESI positive ion mode1-Methylhistidine16.73187503uMMetformin Post
ESI positive ion mode1-Methylhistidine16.89599337uMPlacebo Pre
ESI positive ion mode1-Methylhistidine17.08303871uMPlacebo Pre
ESI positive ion mode1-Methylhistidine17.46519993uMMetformin Pre
ESI positive ion mode1-Methylhistidine17.9421336uMPlacebo Pre
ESI positive ion mode1-Methylhistidine18.33971312uMMetformin Pre
ESI positive ion mode1-Methylhistidine18.37533263uMPlacebo Pre
ESI positive ion mode1-Methylhistidine18.85137028uMPlacebo Pre
ESI positive ion mode1-Methylhistidine19.06732722uMPlacebo Post
ESI positive ion mode1-Methylhistidine19.44992808uMPlacebo Post
ESI positive ion mode1-Methylhistidine19.76839974uMPlacebo Pre
ESI positive ion mode1-Methylhistidine19.77566884uMPlacebo Post
ESI positive ion mode1-Methylhistidine19.77786886uMMetformin Post
ESI positive ion mode1-Methylhistidine20.2502021uMPlacebo Pre
ESI positive ion mode1-Methylhistidine20.37223141uMPlacebo Pre
ESI positive ion mode1-Methylhistidine20.52422395uMPlacebo Pre
ESI positive ion mode1-Methylhistidine20.73803129uMPlacebo Pre
ESI positive ion mode1-Methylhistidine21.01928394uMPlacebo Pre
ESI positive ion mode1-Methylhistidine21.19572097uMMetformin Post
ESI positive ion mode1-Methylhistidine21.79175201uMPlacebo Pre
ESI positive ion mode1-Methylhistidine22.71572792uMPlacebo Post
ESI positive ion mode1-Methylhistidine23.59780561uMMetformin Post
ESI positive ion mode1-Methylhistidine23.67298419uMMetformin Post
ESI positive ion mode1-Methylhistidine23.83426896uMPlacebo Post
ESI positive ion mode1-Methylhistidine24.32194332uMPlacebo Post
ESI positive ion mode1-Methylhistidine25.27943233uMPlacebo Post
ESI positive ion mode1-Methylhistidine26.07098736uMPlacebo Post
ESI positive ion mode1-Methylhistidine41.8317546uMPlacebo Pre
ESI positive ion mode1-Methylhistidine42.0096344uMPlacebo Post
ESI positive ion mode1-Methylhistidine44.66380631uMPlacebo Post
ESI positive ion mode1-Methylhistidine52.08411085uMPlacebo Pre

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