Data for ST000843
| Metabolite structure | All data | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 | F13 | F14 | F15 | F16 | F17 | F18 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 11_12-DiHETrE | 0.00 | 0.00 | 0.00 | 0.01 | 0.00 | 0.00 | 0.01 | 0.00 | 0.00 | 0.01 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | |
| 11(12)-EpETE | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |
| 11(12)-EpETrE | 0.01 | 0.01 | 0.01 | 0.02 | 0.01 | 0.01 | 0.02 | 0.01 | 0.02 | 0.04 | 0.01 | 0.01 | 0.01 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | |
| 11-HETE | 0.02 | 0.01 | 0.02 | 0.08 | 0.03 | 0.01 | 0.03 | 0.01 | 0.04 | 0.09 | 0.01 | 0.02 | 0.01 | 0.01 | 0.00 | 0.00 | 0.01 | 0.00 | |
| 12_13-DiHODE | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |
| 12_13-DiHOME | 0.05 | 0.04 | 0.03 | 0.07 | 0.04 | 0.02 | 0.06 | 0.04 | 0.02 | 0.11 | 0.04 | 0.01 | 0.02 | 0.01 | 0.02 | 0.02 | 0.02 | 0.02 | |
| 12(13)-Ep-9-KODE | 0.06 | 0.08 | 0.06 | 2.47 | 0.40 | 0.11 | 0.04 | 0.08 | 0.60 | 0.62 | 0.10 | 0.08 | 0.02 | 0.03 | 0.02 | 0.04 | 0.04 | 0.02 | |
| 12(13)-EpODE | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | - | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | |
| 12(13)-EpOME | 0.25 | 0.16 | 0.16 | 0.29 | 0.18 | 0.13 | 0.14 | 0.06 | 0.12 | 0.31 | 0.06 | 0.08 | 0.24 | 0.16 | 0.18 | 0.29 | 0.20 | 0.22 | |
| 12-HEPE | 0.04 | 0.02 | 0.01 | 0.06 | 0.04 | 0.01 | 0.04 | 0.00 | 0.03 | 0.04 | 0.01 | 0.01 | - | - | - | - | - | - | |
| 12-HETE | 0.58 | 0.45 | 0.38 | 0.96 | 0.83 | 0.08 | 0.82 | 0.07 | 1.09 | 1.18 | 0.32 | 0.25 | 0.15 | 0.15 | 0.16 | 0.25 | 0.11 | 0.17 | |
| 13-HODE | 0.26 | 0.20 | 0.45 | 1.28 | 0.41 | 0.15 | 0.37 | 0.13 | 0.61 | 1.05 | 0.18 | 0.19 | 0.11 | 0.10 | 0.10 | 0.14 | 0.09 | 0.10 | |
| 13-HOTE | 0.01 | 0.00 | 0.05 | 0.04 | 0.02 | 0.01 | 0.01 | 0.00 | 0.01 | 0.01 | 0.01 | 0.00 | 0.01 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | |
| 13-KODE | 0.07 | 0.04 | 0.05 | 1.84 | 0.25 | 0.07 | 0.04 | 0.02 | 0.33 | 1.70 | 0.03 | 0.04 | 0.03 | 0.01 | 0.02 | 0.03 | 0.02 | 0.03 | |
| 14_15-DiHETE | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |
| 14_15-DiHETrE | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | |
| 14(15)-EpETE | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |
| 14(15)-EpETrE | 0.02 | 0.01 | 0.01 | 0.03 | 0.01 | 0.01 | 0.03 | 0.00 | 0.02 | 0.05 | 0.01 | 0.01 | 0.01 | 0.00 | 0.00 | 0.01 | 0.01 | 0.00 | |
| 14-HDoHE | 0.16 | 0.09 | 0.08 | 0.23 | 0.12 | 0.02 | 0.24 | 0.01 | 0.18 | 0.20 | 0.05 | 0.05 | 0.04 | 0.03 | 0.02 | 0.05 | 0.01 | 0.03 | |
| 15_16-DiHODE | 0.01 | 0.00 | 0.01 | 0.01 | 0.00 | 0.01 | 0.01 | 0.00 | 0.00 | 0.02 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | |
| 15(16)-EpODE | 0.01 | 0.00 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.05 | 0.00 | - | - | - | - | - | - | - | |
| 15-deoxy PGJ2 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.00 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | - | - | - | - | - | - | |
| 15-HEPE | 0.01 | 0.00 | 0.01 | 0.03 | 0.01 | 0.00 | 0.02 | 0.00 | 0.02 | 0.02 | 0.01 | 0.00 | - | - | - | - | - | - | |
| 15-HETE | 0.08 | 0.03 | 0.03 | 0.23 | 0.06 | 0.03 | 0.07 | 0.01 | 0.10 | 0.26 | 0.02 | 0.03 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.00 | |
| 15-KETE | 0.06 | 0.01 | 0.03 | 0.11 | 0.04 | 0.03 | 0.01 | 0.00 | 0.05 | 0.63 | 0.01 | 0.01 | - | - | - | - | - | - | |
| 15-Keto PGE2 | 0.07 | 0.03 | 0.02 | 0.10 | 0.08 | 0.02 | 0.06 | 0.04 | 0.01 | 0.22 | 0.05 | 0.00 | - | - | - | - | - | - | |
| 16(17)-EpDPE | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |
| 17_18-DiHETE | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |
| 17(18)-EpETE | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |
| 17-HDoHE | 0.03 | 0.04 | 0.01 | 0.13 | 0.04 | 0.02 | 0.04 | 0.01 | 0.03 | 0.04 | 0.02 | 0.02 | - | - | - | - | - | - | |
| 19_20-DiHDoPA | 0.01 | 0.00 | 0.00 | 0.01 | 0.01 | 0.00 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | |
| 19(20)-EpDPE | 0.01 | 0.00 | 0.00 | 0.01 | 0.00 | 0.01 | 0.00 | 0.01 | 0.01 | 0.02 | 0.01 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | - | 0.00 | |
| 20-HETE | 0.02 | 0.00 | 0.00 | 0.00 | 0.00 | 0.01 | - | - | - | - | - | - | 0.00 | 0.01 | 0.00 | 0.01 | 0.00 | 0.00 | |
| 4-HDoHE | 0.02 | 0.01 | 0.03 | 0.05 | 0.03 | 0.02 | 0.01 | 0.01 | 0.04 | 0.05 | 0.01 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | |
| 5_15-DiHETE | 0.00 | 0.06 | 0.11 | 0.01 | 0.08 | 0.06 | 0.00 | 0.08 | 0.09 | 0.00 | 0.06 | 0.09 | - | - | - | - | - | - | |
| 5_6-DiHETrE | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |
| 5-HEPE | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |
| 5-HETE | 0.08 | 0.05 | 0.32 | 0.14 | 0.05 | 0.11 | 0.36 | 0.02 | 0.23 | 0.30 | 0.09 | 0.05 | 0.04 | 0.02 | 0.02 | 0.01 | 0.05 | 0.02 | |
| 5-KETE | 0.01 | 0.01 | 0.02 | 0.08 | 0.03 | 0.02 | 0.02 | 0.01 | 0.07 | 0.45 | 0.01 | 0.01 | 0.00 | 0.00 | 0.00 | 0.00 | 0.01 | 0.01 | |
| 6-keto PGF1a | 0.04 | 0.04 | 0.03 | 0.26 | 0.16 | 0.03 | 0.02 | 0.01 | 0.05 | 0.09 | 0.05 | 0.02 | 0.01 | 0.01 | 0.02 | 0.01 | 0.02 | 0.02 | |
| 6-trans-LTB4 | 0.01 | 0.01 | 0.08 | 0.03 | 0.01 | 0.02 | 0.04 | 0.00 | 0.02 | 0.02 | 0.01 | 0.00 | - | - | - | - | 0.01 | - | |
| 8_15-DiHETE | 0.02 | 0.02 | 0.01 | 0.05 | 0.02 | 0.03 | 0.01 | 0.02 | 0.02 | 0.02 | 0.01 | 0.02 | - | - | - | - | - | - | |
| 8_9-DiHETrE | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |
| 8(9)-EpETrE | 0.01 | 0.01 | 0.01 | 0.02 | 0.01 | 0.01 | 0.02 | 0.00 | 0.03 | 0.06 | 0.01 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | |
| 8-HETE | 0.01 | 0.00 | 0.02 | 0.09 | 0.02 | 0.02 | 0.02 | 0.00 | 0.03 | 0.05 | 0.01 | 0.01 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | |
| 9_10-DiHODE | 0.00 | 0.00 | 0.00 | 0.01 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.01 | 0.00 | 0.00 | 0.00 | 0.00 | - | 0.00 | 0.00 | - | |
| 9_10-DiHOME | 0.08 | 0.06 | 0.05 | 0.12 | 0.06 | 0.04 | 0.09 | 0.06 | 0.03 | 0.17 | 0.06 | 0.02 | 0.04 | 0.03 | 0.03 | 0.05 | 0.03 | 0.03 | |
| 9_10-e-DiHO | 10.19 | 9.81 | 13.40 | 13.65 | 8.72 | 9.25 | 8.32 | 9.50 | 5.96 | 13.05 | 6.15 | 6.79 | - | - | - | - | - | - | |
| 9_10-EpO | 1.58 | 1.57 | 1.80 | 1.51 | 1.16 | 1.52 | 1.13 | 1.46 | 0.90 | 1.55 | 0.67 | 1.26 | - | - | - | - | - | - | |
| 9(10)-EpODE | 0.00 | 0.00 | 0.00 | 0.02 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.03 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | |
| 9(10)-EpOME | 0.23 | 0.13 | 0.14 | 0.32 | 0.17 | 0.12 | 0.13 | 0.04 | 0.12 | 0.32 | 0.06 | 0.06 | 0.21 | 0.14 | 0.16 | 0.23 | 0.18 | 0.19 | |
| 9-HEPE | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |
| 9-HETE | 0.01 | 0.01 | 0.03 | 0.06 | 0.02 | 0.01 | 0.01 | 0.01 | 0.02 | 0.04 | 0.01 | 0.01 | - | - | - | - | - | - | |
| 9-HODE | 0.15 | 0.10 | 0.20 | 0.83 | 0.23 | 0.09 | 0.17 | 0.09 | 0.31 | 0.62 | 0.11 | 0.11 | 0.05 | 0.04 | 0.04 | 0.06 | 0.05 | 0.04 | |
| 9-HOTE | 0.00 | 0.00 | 0.01 | 0.02 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.01 | 0.00 | 0.00 | - | - | - | - | - | - | |
| 9-KODE | 0.22 | 0.14 | 0.19 | 5.04 | 0.68 | 0.18 | 0.18 | 0.10 | 0.90 | 3.94 | 0.15 | 0.11 | 0.10 | 0.06 | 0.08 | 0.12 | 0.11 | 0.11 | |
| Lipoxin A4 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | - | - | - | - | - | - | 0.01 | 0.01 | 0.01 | 0.02 | 0.01 | 0.02 | |
| LTB4 | 0.04 | 0.01 | 0.08 | 0.04 | 0.01 | 0.04 | 0.19 | 0.01 | 0.03 | 0.07 | 0.02 | 0.02 | 0.01 | 0.01 | 0.01 | 0.00 | 0.02 | 0.01 | |
| LTB5 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | - | - | - | - | - | - | |
| PGD2 | 0.17 | 0.26 | 0.35 | 0.25 | 0.16 | 0.10 | 0.45 | 0.79 | 0.71 | 0.56 | 1.33 | 0.72 | 0.34 | 0.50 | 0.63 | 0.21 | 0.56 | 0.32 | |
| PGE1 | 0.01 | 0.02 | 0.01 | 0.01 | 0.02 | 0.01 | 0.01 | 0.02 | 0.02 | 0.01 | 0.02 | 0.06 | 0.00 | 0.01 | 0.01 | 0.00 | 0.00 | 0.00 | |
| PGE2 | 0.17 | 0.24 | 0.26 | 0.14 | 0.31 | 0.11 | 0.24 | 0.15 | 0.28 | 0.29 | 0.24 | 0.57 | 0.09 | 0.13 | 0.12 | 0.06 | 0.07 | 0.05 | |
| PGF2a | 0.07 | 0.07 | 0.14 | 0.10 | 0.06 | 0.07 | 0.10 | 0.02 | 0.06 | 0.16 | 0.03 | 0.08 | 0.04 | 0.03 | 0.04 | 0.03 | 0.03 | 0.02 | |
| Resolvin D1 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |
| SUM-TriHOME | 0.21 | 0.22 | 0.30 | 0.41 | 0.24 | 0.17 | 0.35 | 0.28 | 0.34 | 0.48 | 0.25 | 0.21 | 0.04 | 0.04 | 0.04 | 0.05 | 0.04 | 0.04 | |
| TXB2 | 0.08 | 0.06 | 0.08 | 0.09 | 0.18 | 0.05 | 0.09 | 0.03 | 0.10 | 0.09 | 0.05 | 0.04 | 0.04 | 0.02 | 0.05 | 0.02 | 0.06 | 0.02 |
Factors:
| F1 | Treatment:Control | Lung:Left Lung | Time point (day):- |
| F2 | Treatment:Control | Lung:Left Lung | Time point (day):12 |
| F3 | Treatment:Control | Lung:Left Lung | Time point (day):8 |
| F4 | Treatment:Control | Lung:Right Lung | Time point (day):- |
| F5 | Treatment:Control | Lung:Right Lung | Time point (day):12 |
| F6 | Treatment:Control | Lung:Right Lung | Time point (day):8 |
| F7 | Treatment:Pravastatin | Lung:Left Lung | Time point (day):- |
| F8 | Treatment:Pravastatin | Lung:Left Lung | Time point (day):12 |
| F9 | Treatment:Pravastatin | Lung:Left Lung | Time point (day):8 |
| F10 | Treatment:Pravastatin | Lung:Right Lung | Time point (day):- |
| F11 | Treatment:Pravastatin | Lung:Right Lung | Time point (day):12 |
| F12 | Treatment:Pravastatin | Lung:Right Lung | Time point (day):8 |
| F13 | Treatment:Simvastatin | Lung:Left Lung | Time point (day):- |
| F14 | Treatment:Simvastatin | Lung:Left Lung | Time point (day):12 |
| F15 | Treatment:Simvastatin | Lung:Left Lung | Time point (day):8 |
| F16 | Treatment:Simvastatin | Lung:Right Lung | Time point (day):- |
| F17 | Treatment:Simvastatin | Lung:Right Lung | Time point (day):12 |
| F18 | Treatment:Simvastatin | Lung:Right Lung | Time point (day):8 |