Data for ST002846
| Metabolite structure | All data | F1 | F2 | F3 |
|---|---|---|---|---|
| 1,3-bisphospho-D-glycerate | 20129.93 | 19468.10 | 28671.87 | |
| 1-methylnicotinamide+ | 13108761.27 | 9990963.32 | 13285174.35 | |
| 1-phenylethylamine | 924211.94 | 1158658.19 | 788504.04 | |
| 2,3-bisphospho-D-glycerate | - | 10541.06 | 10314.39 | |
| 2- / 3-phosphoglycerate | 1479047.90 | 6321820.64 | 2048625.73 | |
| 2-aminobutanoate / 2-aminoisobutanoate | - | - | - | |
| 2-(Formamido)-N1-(5-phospho-D-ribosyl)acetamidine | 15694.86 | - | 14659.80 | |
| 2-HG | 1008827.13 | 2277867.06 | 1054414.52 | |
| 2-hydroxybutanoic acid | 3267201.78 | 3244310.87 | 4206018.67 | |
| 2-keto-isovaleric acid | 7733141.39 | 4561117.35 | 6658848.77 | |
| 2-ketovaleric acid | 3569601.15 | 2413435.73 | 1678562.38 | |
| 2-oxoadipic acid | - | - | - | |
| 2-oxobutanoic acid | - | - | - | |
| 3,4-dihydroxymandelic acid | - | - | - | |
| 3,4-dihydroxyphenylpropanoate | - | - | - | |
| 3- / 4 -hydroxybutanoic acid | 40087767.70 | 29820383.83 | 27460898.42 | |
| 3- / 4-hydroxyphenylacetic acid / vanillin / | 10146075.84 | 13462570.64 | 15671216.24 | |
| 3- / 7-methylguanine | 376207.17 | 768286.43 | 571897.99 | |
| 3-aminoisobutanoate | 673777.16 | 497560.08 | 390183.66 | |
| 3-hydroxy-anthranilic acid | - | - | - | |
| 3-hydroxykynurenine | 81996.70 | 207608.07 | 153292.85 | |
| 3-hydroxypropanoic acid | - | - | - | |
| 3-methoxytyramine | - | - | - | |
| 3-phosphohydroxypyruvic acid | - | - | - | |
| 3-phospho-serine | 1546178.88 | 8554939.85 | 3116516.53 | |
| 3-ureidopropionic acid | - | - | - | |
| 4-hydroxyphenylpyruvic acid | 42932.56 | 119204.12 | 52941.26 | |
| 4-hydroxyproline / 5-aminolevulinate / N-acetyl-b-alanine | - | 419590.52 | - | |
| 4-phosphopantothenate | 29474.16 | 5571.46 | 12751.66 | |
| 4-trimethylammoniobutanoate+ | 7382174.60 | 19885527.28 | 11333210.72 | |
| 5,6-dihydroxyindole | - | - | 3905329.83 | |
| 5-methylcytosine | 788433.14 | 896093.16 | 1039453.95 | |
| 5-methyl-THF | - | - | - | |
| 5^-methylthioadenosine | 34957223.53 | 237547126.30 | 88551131.91 | |
| 6-aminocaproic acid | - | - | - | |
| 6-methylnicotinamide | 187564.71 | - | 131293.40 | |
| 6-O-methylguanine | - | - | 8510.77 | |
| 6-phosphogluconic acid | 167468.20 | 349719.20 | 109363.03 | |
| 6-phosphoglucono-D-lactone | 13646.09 | 15318.12 | 18568.69 | |
| acetoacetic acid | - | - | - | |
| acetylcholine+ | 5136043.34 | 10307722.11 | 4761202.45 | |
| acetyl-CoA | 50276.85 | - | 31259.75 | |
| aconitic acid | 99709.28 | 397046.37 | 179338.93 | |
| adenine | 2738162.40 | 14530268.28 | 7231808.43 | |
| adenosine | 1448524.44 | 2436438.56 | 2075591.00 | |
| adenylosuccinate | 28720.66 | 39520.20 | 80241.70 | |
| ADP / dGDP | 21214545.35 | 84018120.49 | 44469552.00 | |
| ADP-D-glucose | - | - | - | |
| agmatine | 460002.95 | 179004.33 | 660866.92 | |
| AICA ribonucleotide | - | 667076.27 | - | |
| a-KG | 242824.62 | 263490.73 | 172706.99 | |
| alanine | 93280289.90 | 223905296.38 | 112788967.70 | |
| alanine methyl ester | 10478753.10 | 14135921.37 | 9926922.51 | |
| allantoin | 12755918.71 | 19582046.95 | 15631112.05 | |
| AMP / dGMP | 6979113.70 | 18202612.20 | 11256999.72 | |
| anandamide | 322824.21 | 404415.11 | 147900.26 | |
| arginine | 1741881950.83 | 1218517972.65 | 2380698015.00 | |
| ascorbic acid | - | - | - | |
| asparagine | 1324678.59 | 2464969.60 | 1625511.77 | |
| aspartic acid | 220373500.47 | 511508202.12 | 306384288.30 | |
| ATP / dGTP | 78124713.25 | 285067092.82 | 187346241.22 | |
| b-alanine | 4678895.70 | 79142250.75 | 15539843.75 | |
| betaine | 1588986128.50 | 4507614735.50 | 2862096798.50 | |
| butyric acid | 3101521.99 | 1892167.58 | 2560726.48 | |
| butyric acid(iso) | 979301.41 | 77255.53 | 185628.30 | |
| carbamoyl phosphate | - | - | - | |
| carnitine+ | 19562656.75 | 49137057.58 | 26194792.23 | |
| CDP | 1288544.28 | 5280296.93 | 2340042.90 | |
| CDP-choline | 2042231.60 | 2846191.66 | 5074007.41 | |
| cGMP | - | - | - | |
| choline+ | 2144885612.50 | 3210697201.25 | 2667544677.75 | |
| citraconic acid | 17606924.14 | 19994805.46 | 29868530.88 | |
| citramalic acid | 23048454.65 | 34158814.09 | 29921674.57 | |
| citrate / citrate(iso) | 103273185.48 | 1143728487.70 | 313081450.68 | |
| citrulline | - | - | 31398.82 | |
| CMP | 7964816.14 | 11588357.22 | 10907328.75 | |
| cortisol | 57419.56 | 56084.17 | 37032.59 | |
| creatine | 14201624.31 | 122800240.25 | 22339027.97 | |
| creatinine | 147474383.28 | 369621807.95 | 195026347.10 | |
| CTP | 3604211.22 | 23704231.00 | 10202788.25 | |
| cystathionine | 822365.36 | 3970360.57 | 1216645.26 | |
| cysteine | - | 103660.48 | - | |
| cysteine-S-sulfate | 66473.02 | - | 66623.19 | |
| cystine | 8823498.21 | 621015.16 | 5878556.82 | |
| cytidine | 4375725.36 | 743297.10 | 2446178.07 | |
| cytosine | 3298554.69 | 3799819.67 | 5376611.18 | |
| dADP | - | 20079.51 | - | |
| dAMP | - | 29260.33 | 33803.04 | |
| D-arabinono-1,4-lactone | 111429.87 | - | 178430.15 | |
| dATP | - | 23635.33 | - | |
| dCDP | 8978.70 | 291659.07 | 22857.61 | |
| dCMP | 390449.36 | 2142948.82 | 702483.81 | |
| dCTP | 149220.46 | 2157606.68 | 507977.03 | |
| dehydroascorbic acid | 19343.29 | 20461.33 | - | |
| deoxyguanosine | - | - | - | |
| deoxyinosine | 17934.52 | 21457.51 | 135965.24 | |
| deoxyuridine | 591518.63 | 1231299.27 | 752295.76 | |
| D-erythrose-4-phosphate | - | - | - | |
| D-galactonic acid / D-gluconic acid | 1060606.99 | 6343648.92 | 2564665.55 | |
| D-galactosamine/glucosamine-1-phosphate | - | - | - | |
| D-galactosamine/glucosamine-6-phosphate | 17488.33 | 41410.33 | 10007.47 | |
| dihydroorotate | 43069.31 | - | 35702.21 | |
| dimethylglycine | - | 6754676.10 | 1895923.60 | |
| DL-DOPA | - | - | - | |
| DOPAC | 21483.93 | 30202.66 | 12382.72 | |
| DOPAL | 381983.23 | 312477.36 | 283771.53 | |
| dopamine | 535628.39 | 536860.25 | 363208.93 | |
| dopamine quinone | - | 4464017.85 | 14979914.19 | |
| DOPEG | 759377.42 | 627978.23 | 571531.18 | |
| DOPET | 225137.27 | 94094.82 | 320608.76 | |
| D-ribose-1/5-phosphate / D-ribulose 5-phosphate | 165540.81 | 1449567.29 | 385757.29 | |
| D-sedoheptulose-7-phosphate | 444281.37 | 1784772.40 | 505646.62 | |
| dTMP | - | - | - | |
| dTTP | 9542.25 | 166817.56 | - | |
| dUMP | - | - | - | |
| dUTP | - | - | - | |
| epinephrine | 121639.14 | 65464.52 | 159084.29 | |
| ethyl acetate | 6988266.24 | 9075520.33 | 9519695.82 | |
| F-1,6/2,6-DP | 3622676.52 | 14414772.83 | 5537216.00 | |
| F1P | 21902.48 | 28685.86 | 40514.88 | |
| F6P / G1P / G6P | 5242360.15 | 12391177.67 | 4906466.93 | |
| FAD | - | - | 71081.06 | |
| FMN | - | - | - | |
| folic acid | 2924873.51 | 2915190.33 | 2943062.44 | |
| fructose / mannose | 126629045.56 | 111534902.11 | 114368007.63 | |
| fumaric acid | 133867.11 | 1031571.06 | 302089.55 | |
| GABA | 1627393.64 | 8529854.00 | 2238846.00 | |
| galactosamine / glucosamine | 1265483.87 | 161603.30 | 479895.20 | |
| galactose / glucose | 668106276.15 | 431436100.62 | 519245857.18 | |
| GalNAC/GlcNAC/ManNAC | 3262339.07 | 1289530.32 | 3902107.55 | |
| GAP / DHAP | 517864.78 | 3743453.09 | 726851.36 | |
| GDP | 2169259.42 | 5890815.74 | 4509314.12 | |
| GDP-L-fucose | 581934.91 | 1434037.73 | 796779.35 | |
| glucono-lactone | 2014966.05 | 1127534.36 | 958656.02 | |
| glutaconic acid | 2013503.23 | 1771688.67 | 2061145.39 | |
| glutamine | 93264131.42 | 151335944.25 | 102769421.47 | |
| glutaminic acid | 86958150.35 | 279553705.80 | 119471128.53 | |
| glutathione | 510910.71 | 2843039.55 | 989604.83 | |
| glutathione disulfide | 86608432.56 | 202511602.35 | 130876900.25 | |
| glyceraldehyde | 244174382.78 | 69322736.17 | 143606451.25 | |
| glyceric acid | 8356574.64 | 1328804.59 | 2482027.59 | |
| glycerol 2/3-phosphate | 10705089.19 | 37884304.85 | 14041178.38 | |
| glycine | 10469082.16 | 18862994.85 | 10519018.32 | |
| glycylglycine | - | - | - | |
| GMP | 1181934.14 | 2873002.30 | 2354591.30 | |
| GTP | 3723377.75 | 19669533.32 | 12035423.32 | |
| guanidine | 4556016.06 | 1044496.90 | 2379751.94 | |
| guanidinoacetate | - | 2191602.10 | - | |
| guanine | 197179.23 | 217774.11 | 636520.87 | |
| guanosine | 299740.74 | 163375.21 | 529592.97 | |
| gulonic-lactone | 6653643.39 | 4342511.46 | 6473795.10 | |
| histamine | - | - | - | |
| histidine | 52161102.73 | 66265536.52 | 63911522.85 | |
| homocysteine | 119309.07 | - | 29175.40 | |
| homoserine / theronine | 52685439.75 | 83197880.60 | 59218075.53 | |
| homovanillic acid | 40666.71 | 20636.20 | 22219.17 | |
| hydroxyphenyllactic acid | 1056630.28 | 3372510.04 | 1834655.65 | |
| hypoxanthine | 8590699.86 | 2736479.89 | 11094872.49 | |
| IDA | 588031.83 | 674846.69 | 483474.08 | |
| IDP | - | - | 26294.24 | |
| imidazole-4-acetate | 20857.65 | 158425.98 | 45742.14 | |
| IMP | 1009928.65 | 2309859.49 | 2435032.65 | |
| inosine | 18566.32 | 29714.03 | 42575.97 | |
| isonictinic acid | 217107.00 | - | 139722.04 | |
| itaconic acid | 859619.67 | 1055034.94 | 833241.80 | |
| kynurenic acid | 39816.46 | 49502.42 | 90130.24 | |
| kynurenine | 582843.81 | 1024277.16 | 673859.31 | |
| lactic acid | 2942796508.50 | 3842693401.50 | 3245357405.25 | |
| L-arginino-succinate | 577319.41 | 1433784.74 | 797370.41 | |
| L-cysteic acid | - | - | - | |
| leucine / leucine(iso) | 3238706340.75 | 2888221836.50 | 2399894040.75 | |
| levulinic acid | 5481986.79 | 7171871.36 | 6323944.06 | |
| L-NMMA | 8956646.21 | 34869404.95 | 14468948.46 | |
| L-tyrosine methyl ester | 65852.00 | 85238.17 | 103820.83 | |
| lysine | 933018891.20 | 2347545281.75 | 1196197341.03 | |
| maleic acid | 1707839.84 | 5126735.46 | 2614568.59 | |
| malic acid | 18688687.09 | 62550786.70 | 29490130.53 | |
| malonyl-CoA | 29175.98 | 16774.78 | 28981.20 | |
| mesaconic acid | - | - | - | |
| methionine | 463929469.45 | 532729683.50 | 522714859.95 | |
| methyl acetoacetate | - | - | - | |
| methylglyoxal | - | - | - | |
| methylmalonic acid | 159707570.59 | 222304617.18 | 265231960.78 | |
| mevalonic acid | 11987928.13 | 9049155.53 | 10170210.76 | |
| N1/N8-acetylspermidine | 42790.38 | 120930.51 | 37895.94 | |
| N-acetylaspartic acid | 991583.92 | 1109584.34 | 1825784.26 | |
| N-acetylaspartylglutamic acid | 21101.22 | 194122.00 | 61151.68 | |
| N-acetyl-DL-alanine | 50534934.78 | 74777072.42 | 59668708.49 | |
| N-acetyl-DL-serine | 59979360.67 | 6114657.88 | 14028778.86 | |
| N-acetyl-dopamine | - | - | - | |
| N-acetylglucosamine 1/6-phosphate | 991529.90 | 2010272.78 | 1192573.43 | |
| N-acetyl-L-glutamic acid | - | 43238.92 | - | |
| NAD+ | 29942489.37 | 96626491.13 | 44687310.16 | |
| NADH | - | - | - | |
| NADP+ | 2329320.29 | 8676014.31 | 4434443.85 | |
| NADPH | 23881.55 | 128321.75 | 37426.57 | |
| N-carbamoyl-L-aspartate | - | 1082050.83 | 28757.91 | |
| nebularine | 17926.91 | 21404.62 | 135960.22 | |
| nicotinamide | 179590598.22 | 329635470.02 | 264920371.00 | |
| nicotinamide riboside+ | - | - | - | |
| nicotinic acid | 3693195.47 | 3546804.03 | 2452798.03 | |
| N-methyltryptamine | - | 9332.98 | 7687.58 | |
| NMN | 121269.55 | 571752.35 | 249402.84 | |
| norepinephrine | 3913785.72 | 7517607.97 | 2237545.79 | |
| O-acetyl-L-serine | 13869566.55 | 26176512.35 | 19340326.55 | |
| octopamine | 1153132.59 | 1592600.92 | 1324859.71 | |
| ornithine | 35627624.06 | 1035731680.17 | 60415775.21 | |
| orotic acid | 87897.26 | 104484.65 | 315836.96 | |
| orotidylic acid | - | - | 18709.10 | |
| oxalacetic acid | - | - | 260524.11 | |
| pantothenic acid | 211630598.88 | 128140894.19 | 126130913.94 | |
| phenethylamine | - | - | - | |
| phenylalanine | 403901866.75 | 644620268.42 | 494987162.15 | |
| phenylephrine / synephrine | 47102.90 | 35513.93 | 67656.86 | |
| phosphocreatine | 473451148.15 | 2975765385.50 | 721188957.27 | |
| phosphoenolpyruvate | 301985.98 | 1339807.30 | 368283.84 | |
| phosphorylcholine+ | 371964522.30 | 1949190726.25 | 570409673.55 | |
| picolinic acid | 6624410.40 | 4317654.07 | 4969629.80 | |
| proline | 103484963.57 | 56786990.21 | 59653606.10 | |
| propionic acid | 9298257.41 | - | - | |
| PRPP | - | - | - | |
| pseudouridine | 2528372.56 | 1583965.69 | 1710499.90 | |
| putrescine | 308973.23 | 399847.24 | 398859.91 | |
| pyridoxine | - | - | - | |
| pyroglutamic acid | 2258047451.25 | 1881825836.67 | 1544089802.00 | |
| pyrroline hydroxycarboxylic acid | 23474811.50 | 39900135.86 | 27090288.37 | |
| pyruvic acid | 214887439.70 | 215751249.72 | 172802745.70 | |
| quinolinic acid | 22598.93 | 105288.43 | 28134.59 | |
| (S)-4-hydroxymandelonitrile | 765671.68 | 1810822.29 | 1287493.06 | |
| S-adenosyl-L-homocysteine | - | - | - | |
| S-adenosyl-L-methionine+ | 2675185.69 | 31170397.70 | 5996886.81 | |
| S-adenosylmethioninamine+ | 18499.54 | 21888.62 | 8941.37 | |
| SAICAR | - | 53131.47 | - | |
| sarcosine | 55113791.22 | 82671972.96 | 32350709.06 | |
| serine | 11577673.82 | 17955358.27 | 13792122.10 | |
| serotonin | 79636.21 | 54813.36 | 33755.79 | |
| sorbitol / galactitol / L-iditol / manitol | 296276450.65 | 252711240.57 | 252669898.10 | |
| spermidine | 41852099.08 | 38557403.71 | 114776204.42 | |
| spermine | 637298.15 | 281189.41 | 601768.39 | |
| succinic acid | 45313782.18 | 61873899.12 | 51816942.97 | |
| succinic semialdehyde | - | - | - | |
| succinyl-CoA | 11000.27 | 51328.93 | 25099.27 | |
| taurine | 2932177578.25 | 3638165936.50 | 2179697476.20 | |
| thiamine+ | - | - | - | |
| thymidine | 3046403.79 | 1207900.91 | 3415058.85 | |
| thymine | 1597408.66 | 1756298.98 | 1334106.35 | |
| tryptamine | 28909.49 | 35259.47 | 15952.60 | |
| tryptophan | 50707984.49 | 90401206.53 | 61890337.33 | |
| tyramine | 838238.18 | 1231513.09 | 1148505.45 | |
| tyrosine | 581444121.48 | 515622341.00 | 477849929.90 | |
| UDP | 1577193.93 | 7392345.03 | 2806582.05 | |
| UDP-D-glucose | 4860167.04 | 15368803.59 | 6948684.39 | |
| UDP-N-acetyl-galactosamine/UDP-N-acetyl-glucosamine | 8570326.39 | 18949406.75 | 10385437.99 | |
| UMP | 10560931.48 | 37686327.52 | 14330917.32 | |
| uracil | 13474075.00 | 20464225.93 | 15452397.00 | |
| urea | 599593.59 | 2361815.73 | 1062086.43 | |
| uric acid | 2986572.24 | 3473665.62 | 2389319.28 | |
| uridine | 1668120.22 | 332320.99 | 2042465.38 | |
| UTP | 4229187.51 | 21326518.14 | 7697685.10 | |
| valine | 893697132.15 | 697152693.05 | 460781709.23 | |
| xanthine | 4022476.94 | 2509699.47 | 4485337.53 | |
| xanthosine | 30634.75 | - | - | |
| xanthurenic acid | 7210.49 | - | - | |
| XMP | 38014.72 | 175759.79 | 70129.91 | |
| y-glutamylcysteine | - | - | - |
Factors:
| F1 | genotype:ApoE-KO | treatment:no treatment |
| F2 | genotype:wild-type | treatment:IL-4 |
| F3 | genotype:wild-type | treatment:no treatment |
