Data for ST004164
| Metabolite structure | All data | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 | F13 | F14 | F15 | F16 | F17 | F18 | F19 | F20 | F21 | F22 | F23 | F24 | F25 | F26 | F27 | F28 | F29 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Acetyl-CoA | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |
| Adenine | 8077037.00 | 10004015.00 | 9701032.00 | 8649979.00 | 9352425.00 | 4381183.00 | 4073349.00 | 3772020.00 | 5221655.00 | 5994059.00 | 6534384.00 | 7246007.00 | 6064514.00 | 5307835.00 | 6361569.00 | 8377334.00 | 12484783.00 | 11111987.00 | 7948946.00 | 11223329.00 | 7076101.29 | 4992849.00 | 6434826.00 | 4174415.00 | 6630004.00 | 9649181.00 | 9148978.00 | 7678355.00 | 7163925.50 | |
| Adenosine | 124264.00 | 152085.00 | 207675.00 | 105933.00 | 113307.00 | 70254.00 | 75229.00 | 61727.00 | 52947.00 | 199190.00 | 99146.00 | 208600.00 | 119792.00 | 104432.00 | 132588.00 | 245139.00 | 253549.00 | 212922.00 | 98090.00 | 115738.00 | 114467.00 | 93376.00 | 104960.00 | 68912.00 | 68657.00 | 255261.00 | 131850.00 | 108095.00 | 139832.00 | |
| Adenosine diphosphate ribose | 1253.00 | 895.00 | 1120.00 | 774.00 | 912.00 | 1208.00 | 919.00 | 868.00 | 842.00 | 850.00 | 924.00 | 1078.00 | 859.00 | 774.00 | 883.00 | 782.00 | 1118.00 | 916.00 | 964.00 | 1477.00 | 770.29 | 575.00 | 828.00 | 599.00 | 909.00 | 909.00 | 804.00 | 834.00 | 685.17 | |
| ADP | 150195.00 | 135620.00 | 161271.00 | 143669.00 | 118421.00 | 117957.00 | 139858.00 | 136924.00 | 113562.00 | 62605.00 | 73471.00 | 79205.00 | 137733.00 | 117425.00 | 197902.00 | 159733.00 | 205208.00 | 179106.00 | 136706.00 | 72127.00 | 90578.43 | 67059.00 | 56441.00 | 52768.00 | 107513.00 | 157100.00 | 116982.00 | 96766.00 | 103826.50 | |
| AMP | 77355.00 | 59002.00 | 71002.00 | 64694.00 | 67607.00 | 59350.00 | 63316.00 | 77482.00 | 92039.00 | 50660.00 | 50346.00 | 58800.00 | 86025.00 | 87108.00 | 100937.00 | 79623.00 | 104376.00 | 75870.00 | 72891.00 | 53986.00 | 57602.14 | 56077.00 | 48451.00 | 43572.00 | 61564.00 | 66343.00 | 50750.00 | 44738.00 | 77206.50 | |
| ATP | 334361.00 | 339707.00 | 344419.00 | 321075.00 | 293314.00 | 257488.00 | 237147.00 | 252046.00 | 256725.00 | 281816.00 | 299473.00 | 306682.00 | 313193.00 | 274804.00 | 299556.00 | 339452.00 | 335970.00 | 318727.00 | 293154.00 | 313620.00 | 271486.00 | 171248.00 | 242890.00 | 203934.00 | 271316.00 | 313617.00 | 306113.00 | 268301.00 | 297402.00 | |
| CDP | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |
| CMP | 2643.00 | 1585.00 | 1668.00 | 1292.00 | 1511.00 | 1697.00 | 1489.00 | 1800.00 | 1929.00 | 1128.00 | 1134.00 | 1312.00 | 1509.00 | 1092.00 | 1702.00 | 1194.00 | 1555.00 | 1303.00 | 1856.00 | 1328.00 | 835.14 | 756.00 | 991.00 | 882.00 | 1565.00 | 1687.00 | 887.00 | 1249.00 | 912.17 | |
| CTP | 13773.00 | 13949.00 | 15769.00 | 14419.00 | 11657.00 | 13264.00 | 10086.00 | 11090.00 | 9519.00 | 12011.00 | 13625.00 | 14747.00 | 7812.00 | 6291.00 | 7061.00 | 8180.00 | 8951.00 | 8607.00 | 12967.00 | 14926.00 | 6952.43 | 7879.00 | 10849.00 | 7916.00 | 11443.00 | 14569.00 | 13972.00 | 11824.00 | 6398.17 | |
| Cytidine | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |
| Cytosine | 11251.00 | 18126.00 | 19711.00 | 17712.00 | 15287.00 | 7984.00 | 8346.00 | 8326.00 | 5892.00 | 12131.00 | 13233.00 | 17346.00 | 9946.00 | 6469.00 | 8999.00 | 14158.00 | 26459.00 | 26449.00 | 8383.00 | 14348.00 | 10461.14 | 5502.00 | 4385.00 | 6191.00 | 8315.00 | 14605.00 | 15150.00 | 12481.00 | 11292.67 | |
| Fenclonine (IS) | 91192.00 | 67912.00 | 76304.00 | 72970.00 | 69061.00 | 92540.00 | 94052.00 | 88405.00 | 85148.00 | 65011.00 | 66096.00 | 71078.00 | 94968.00 | 91274.00 | 90913.00 | 74102.00 | 65933.00 | 76185.00 | 86418.00 | 65503.00 | 93926.57 | 107781.00 | 99622.00 | 86299.00 | 110413.00 | 86441.00 | 90160.00 | 84442.00 | 95742.00 | |
| GABA | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |
| GDP | 6472.00 | 6207.00 | 6792.00 | 6272.00 | 6359.00 | 6044.00 | 5553.00 | 5931.00 | 5761.00 | 4766.00 | 5003.00 | 5789.00 | 5869.00 | 5391.00 | 6544.00 | 6002.00 | 7375.00 | 7087.00 | 6353.00 | 4310.00 | 5266.29 | 5305.00 | 4462.00 | 4375.00 | 5605.00 | 7365.00 | 6386.00 | 5952.00 | 5671.50 | |
| GMP | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |
| GSH | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |
| GSNO | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |
| GSSG | 1418183.00 | 1225249.00 | 1333941.00 | 1186362.00 | 994786.00 | 1049909.00 | 960685.00 | 1148870.00 | 1181685.00 | 946168.00 | 992382.00 | 1124261.00 | 1066445.00 | 934419.00 | 1079493.00 | 964163.00 | 986188.00 | 953450.00 | 1153423.00 | 1255405.00 | 909799.57 | 625927.00 | 830450.00 | 735803.00 | 1092400.00 | 1182207.00 | 1089961.00 | 956960.00 | 805272.50 | |
| GTP | 32584.00 | 30268.00 | 32002.00 | 28340.00 | 23601.00 | 25216.00 | 20604.00 | 23558.00 | 23039.00 | 25033.00 | 27735.00 | 27507.00 | 26708.00 | 21884.00 | 23778.00 | 25938.00 | 26120.00 | 24577.00 | 28568.00 | 30997.00 | 22076.43 | 16501.00 | 25110.00 | 18095.00 | 27092.00 | 28171.00 | 26513.00 | 25077.00 | 21926.50 | |
| Guanine | 143959.00 | 366859.00 | 328962.00 | 345819.00 | 375049.00 | 112226.00 | 112396.00 | 118988.00 | 118279.00 | 322121.00 | 310779.00 | 414613.00 | 145346.00 | 116384.00 | 150347.00 | 304534.00 | 755118.00 | 657002.00 | 149907.00 | 129220.00 | 187186.57 | 121465.00 | 102754.00 | 67921.00 | 124266.00 | 414559.00 | 353859.00 | 275587.00 | 210697.83 | |
| Guanosine | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |
| Malonyl-CoA | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |
| NAD+ | 35604.00 | 37038.00 | 48893.00 | 30403.00 | 33911.00 | 35026.00 | 36837.00 | 54513.00 | 33301.00 | 66106.00 | 68073.00 | 73239.00 | 42972.00 | 30347.00 | 38091.00 | 37796.00 | 66713.00 | 46342.00 | 26868.00 | 43314.00 | 24111.43 | 17746.00 | 26488.00 | 15301.00 | 33041.00 | 58341.00 | 43927.00 | 33594.00 | 29847.50 | |
| NADH | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |
| NADP+ | 3264.00 | 3444.00 | 3778.00 | 2607.00 | 3148.00 | 2799.00 | 3092.00 | 4724.00 | 2287.00 | 4847.00 | 5447.00 | 5428.00 | 3730.00 | 3130.00 | 4043.00 | 4189.00 | 6653.00 | 4877.00 | 2462.00 | 4725.00 | 3726.29 | 3600.00 | 3333.00 | 2687.00 | 4021.00 | 4417.00 | 4271.00 | 4075.00 | 3601.00 | |
| NADPH | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |
| Nicotinamide riboside | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |
| Nicotinic acid riboside | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |
| Succinyl-CoA | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |
| Total protein | 286.00 | 380.60 | 279.20 | 245.40 | 204.80 | 373.80 | 265.60 | 286.00 | 292.60 | 326.40 | 340.00 | 279.20 | 245.40 | 326.40 | 292.60 | 238.60 | 428.00 | 272.40 | 326.40 | 292.60 | 296.54 | 313.00 | 286.00 | 286.00 | 265.60 | 286.00 | 313.00 | 482.00 | 267.93 |
Factors:
| F1 | Sample source:mouse primary astrocytes | Genotype:Ent10 knockout | treatment:TNFš¯¯°/IL-1š¯¯° |
| F2 | Sample source:mouse primary astrocytes | Genotype:Ent11 knockout | treatment:TNFš¯¯°/IL-1š¯¯° |
| F3 | Sample source:mouse primary astrocytes | Genotype:Ent12 knockout | treatment:TNFš¯¯°/IL-1š¯¯° |
| F4 | Sample source:mouse primary astrocytes | Genotype:Ent13 knockout | treatment:TNFš¯¯°/IL-1š¯¯° |
| F5 | Sample source:mouse primary astrocytes | Genotype:Ent14 knockout | treatment:TNFš¯¯°/IL-1š¯¯° |
| F6 | Sample source:mouse primary astrocytes | Genotype:Ent15 knockout | treatment:TNFš¯¯°/IL-1š¯¯°/Forodesine |
| F7 | Sample source:mouse primary astrocytes | Genotype:Ent16 knockout | treatment:TNFš¯¯°/IL-2š¯¯°/Forodesine |
| F8 | Sample source:mouse primary astrocytes | Genotype:Ent17 knockout | treatment:TNFš¯¯°/IL-3š¯¯°/Forodesine |
| F9 | Sample source:mouse primary astrocytes | Genotype:Ent18 knockout | treatment:TNFš¯¯°/IL-4š¯¯°/Forodesine |
| F10 | Sample source:mouse primary astrocytes | Genotype:Ent19 knockout | treatment:TNFš¯¯°/IL-5š¯¯°/Forodesine |
| F11 | Sample source:mouse primary astrocytes | Genotype:Ent20 knockout | treatment:TNFš¯¯°/IL-6š¯¯°/Forodesine |
| F12 | Sample source:mouse primary astrocytes | Genotype:Ent21 knockout | treatment:TNFš¯¯°/IL-7š¯¯°/Forodesine |
| F13 | Sample source:mouse primary astrocytes | Genotype:Ent2 knockout | treatment:Vehicle |
| F14 | Sample source:mouse primary astrocytes | Genotype:Ent3 knockout | treatment:Vehicle |
| F15 | Sample source:mouse primary astrocytes | Genotype:Ent4 knockout | treatment:Vehicle |
| F16 | Sample source:mouse primary astrocytes | Genotype:Ent5 knockout | treatment:Vehicle |
| F17 | Sample source:mouse primary astrocytes | Genotype:Ent6 knockout | treatment:Vehicle |
| F18 | Sample source:mouse primary astrocytes | Genotype:Ent7 knockout | treatment:Vehicle |
| F19 | Sample source:mouse primary astrocytes | Genotype:Ent8 knockout | treatment:TNFš¯¯°/IL-1š¯¯° |
| F20 | Sample source:mouse primary astrocytes | Genotype:Ent9 knockout | treatment:TNFš¯¯°/IL-1š¯¯° |
| F21 | Sample source:mouse primary astrocytes | Genotype:Wild-type | treatment:TNFš¯¯°/IL-1š¯¯° |
| F22 | Sample source:mouse primary astrocytes | Genotype:Wild-type | treatment:TNFš¯¯°/IL-1š¯¯°/Forodesine |
| F23 | Sample source:mouse primary astrocytes | Genotype:Wild-type | treatment:TNFš¯¯°/IL-2š¯¯°/Forodesine |
| F24 | Sample source:mouse primary astrocytes | Genotype:Wild-type | treatment:TNFš¯¯°/IL-3š¯¯°/Forodesine |
| F25 | Sample source:mouse primary astrocytes | Genotype:Wild-type | treatment:TNFš¯¯°/IL-4š¯¯°/Forodesine |
| F26 | Sample source:mouse primary astrocytes | Genotype:Wild-type | treatment:TNFš¯¯°/IL-5š¯¯°/Forodesine |
| F27 | Sample source:mouse primary astrocytes | Genotype:Wild-type | treatment:TNFš¯¯°/IL-6š¯¯°/Forodesine |
| F28 | Sample source:mouse primary astrocytes | Genotype:Wild-type | treatment:TNFš¯¯°/IL-7š¯¯°/Forodesine |
| F29 | Sample source:mouse primary astrocytes | Genotype:Wild-type | treatment:Vehicle |
