Metabolomics Workbench : NIH Data Repository : Analyze Studies

Data for ST004205

(Analysis AN006994): Average values per metabolite and experimental factor (Units:normalized peak area)

Metabolite structure	F1	F2	F3	F4	F5	F6	F7	F8	F9	F10
1,3-15N2-Uric acid	-	-	-	-	-	-	-	-	-	-
13C10,15N5-Adenosine	-	-	-	-	-	-	-	-	-	-
13C3-Thiamine	-	-	-	-	-	-	-	-	-	-
13C5-Hypoxanthine	-	-	-	-	-	-	-	-	-	-
13C5-Xanthosine	-	-	-	-	-	-	-	-	-	-
15N4-Inosine	-	-	-	-	-	-	-	-	-	-
1-Methylhistidine	0.01	0.01	0.00	0.00	0.00	0.00	0.00	0.00	0.01	0.00
1-Methylnicotinamide	0.38	0.40	0.25	0.28	0.23	0.38	0.29	0.28	0.08	0.09
1-Methylxanthine	-	-	-	-	-	-	-	-	-	-
1-Methylxanthosine	-	-	-	-	-	-	-	-	-	-
2-Aminobenzoic acid	-	-	-	-	-	-	-	-	-	-
3-Hydroxybutyric acid	-	-	-	-	-	-	-	-	-	-
3-Hydroxykynurenine	-	-	-	-	-	-	-	-	-	-
3-Hydroxy-N6,N6,N6-Trimethyllysine	0.00	0.01	0.00	0.00	0.00	0.00	0.01	0.00	0.00	0.00
3-Hydroxytyrosol	-	-	-	-	-	-	-	-	-	-
3-Methoxytyrosine	-	-	-	-	-	-	-	-	-	-
3-Methylxanthine	-	-	-	-	-	-	-	-	-	-
3-Methylxanthosine	-	-	-	-	-	-	-	-	-	-
4-Hydroxyproline	0.02	0.03	0.02	0.02	0.01	0.02	0.01	0.01	0.02	0.02
4-Trimethylammoniobutanal	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
5-Glutamylalanine	-	-	-	-	-	-	-	-	-	-
5-Hydroxyindoleacetic acid	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
5-Hydroxytryptophan	0.00	0.01	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
5^-Methylthioadenosine	0.64	0.53	0.34	0.37	0.30	0.54	0.27	0.23	0.47	0.31
6-Aminouracil	-	-	-	-	-	-	-	-	-	-
6C13-Phenylalanine	-	-	-	-	-	-	-	-	-	-
6C13-Tyrosine	-	-	-	-	-	-	-	-	-	-
7-alpha-Hydroxy-3-oxo-4-cholestenoate	-	-	-	-	-	-	-	-	-	-
7-Methylguanine	-	-	-	-	-	-	-	-	-	-
7-Methylguanosine	-	-	-	-	-	-	-	-	-	-
7-Methylxanthine	-	-	-	-	-	-	-	-	-	-
7-Methylxanthosine	-	-	-	-	-	-	-	-	-	-
8-Hydroxy-deoxyguanosine	-	-	-	-	-	-	-	-	-	-
8-Hydroxyguanosine	0.01	0.01	0.01	0.01	0.01	0.02	0.01	0.01	0.01	0.01
8-Oxo-deoxyguanosine-13C,15N2	-	-	-	-	-	-	-	-	-	-
9-Hexadecenoylcarnitine	0.04	0.03	0.03	0.03	0.02	0.02	0.02	0.02	0.05	0.04
Acetylcarnitine	0.09	0.08	0.07	0.05	0.04	0.05	0.05	0.04	0.05	0.05
Acetylcarnitine-d3	-	-	-	-	-	-	-	-	-	-
Adenine	0.67	0.69	0.72	0.60	0.72	0.44	0.70	0.84	0.40	0.53
Adenosine	0.10	0.11	0.12	0.10	0.08	0.07	0.10	0.09	0.08	0.10
Adenosine diphosphate ribose	-	-	-	-	-	-	-	-	-	-
Adenosylcobalamin	-	-	-	-	-	-	-	-	-	-
AICA-riboside	-	-	-	-	-	-	-	-	-	-
Alanine	0.12	0.14	0.10	0.07	0.06	0.08	0.06	0.06	0.10	0.10
Alanine-d4	-	-	-	-	-	-	-	-	-	-
alpha-Tocopherol	-	-	-	-	-	-	-	-	-	-
Arabitol	0.59	0.56	0.61	0.41	0.54	0.55	0.56	0.56	0.63	0.68
Arginine	0.21	0.17	0.22	0.18	0.15	0.18	0.17	0.14	0.21	0.17
Arginine-d4C13	-	-	-	-	-	-	-	-	-	-
Ascorbate	-	-	-	-	-	-	-	-	-	-
Asparagine	1.17	1.38	1.08	0.83	0.73	0.94	0.74	0.65	1.25	1.28
Aspartic acid	-	-	-	-	-	-	-	-	-	-
Aspartic acid-d3	-	-	-	-	-	-	-	-	-	-
Asymmetric dimethylarginine	6.37	7.02	6.21	5.05	4.37	5.57	5.14	4.25	7.33	6.31
Betaine	1.05	1.33	1.00	1.08	1.06	1.05	1.12	0.99	1.06	1.13
Betaine-d11	-	-	-	-	-	-	-	-	-	-
Bilirubin	-	-	-	-	-	-	-	-	-	-
Butyrobetaine	0.08	0.14	0.08	0.06	0.06	0.07	0.05	0.06	0.06	0.07
Butyrylcarnitine	0.04	0.05	0.03	0.03	0.02	0.03	0.02	0.02	0.03	0.02
Butyrylcarnitine-d3	-	-	-	-	-	-	-	-	-	-
Cadaverine	-	-	-	-	-	-	-	-	-	-
cADPRibose	0.01	0.02	0.01	0.01	0.01	0.01	0.01	0.00	0.01	0.01
Caffeine	-	-	-	-	-	-	-	-	-	-
Capsaicin	-	-	-	-	-	-	-	-	-	-
Carnitine	0.09	0.17	0.07	0.05	0.05	0.07	0.04	0.04	0.08	0.08
Carnitine-d9	-	-	-	-	-	-	-	-	-	-
Choline	0.20	0.27	0.19	0.12	0.13	0.16	0.12	0.12	0.16	0.17
Citrulline	0.04	0.02	0.01	0.01	0.01	0.01	0.01	0.01	0.02	0.01
Citrulline-d2	-	-	-	-	-	-	-	-	-	-
Cotinine	-	-	-	-	-	-	-	-	-	-
Creatine	0.82	1.00	0.75	0.58	0.55	0.62	0.52	0.46	1.00	0.92
Creatinine	0.06	0.05	0.05	0.04	0.03	0.08	0.03	0.03	0.07	0.06
Creatinine-d3	-	-	-	-	-	-	-	-	-	-
Curcumin	-	-	-	-	-	-	-	-	-	-
Cyanocobalamin	-	-	-	-	-	-	-	-	-	-
Cystathionine	-	-	-	-	-	-	-	-	-	-
Cysteine	-	-	-	-	-	-	-	-	-	-
Cysteinylglycine	0.02	0.02	0.02	0.02	0.02	0.02	0.02	0.02	0.02	0.02
Cystine	0.00	-	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Cytosine	-	-	-	-	-	-	-	-	-	-
Decanoylcarnitine	-	-	-	-	-	-	-	-	-	-
Demethoxycurcumin	-	-	-	-	-	-	-	-	-	-
Deoxyadenosine	0.02	0.03	0.04	0.03	0.03	0.03	0.02	0.07	0.03	0.05
Deoxyguanosine	-	-	-	-	-	-	-	-	-	-
Deoxyinosine	-	-	-	-	-	-	-	-	-	-
Dimethylethanolamine	0.02	0.01	0.01	0.01	0.01	0.03	0.01	0.01	0.02	0.02
Dimethylglycine	-	-	-	-	-	-	-	-	-	-
DNL201	-	-	-	-	-	-	-	-	-	-
Dodecanoylcarnitine	-	-	-	-	-	-	-	-	-	-
Dopa	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.01	0.00	0.00
Dopamine	0.02	0.01	0.02	0.01	0.01	0.02	0.01	0.01	0.02	0.02
Dopamine 3-o-sulfate	-	-	-	-	-	-	-	-	-	-
Dopamine 4-o-sulfate	-	-	-	-	-	-	-	-	-	-
Epinephrine	0.02	0.02	0.02	0.01	0.01	0.01	0.01	0.01	0.02	0.02
Ergothioneine	0.06	0.09	0.04	0.02	0.03	0.03	0.02	0.02	0.04	0.04
Ethanolamine	0.02	0.02	0.01	0.02	0.01	0.01	0.03	0.01	0.01	0.00
Formylanthranilic acid	-	-	-	-	-	-	-	-	-	-
gamma-Aminobutyric acid	0.00	0.00	0.00	-	0.00	0.00	-	0.00	0.00	0.00
Gamma-Glutamylcysteine	-	-	-	-	-	-	-	-	-	-
Glucosamine	-	-	-	-	-	-	-	-	-	-
Glucose	0.04	0.03	0.04	0.03	0.03	0.03	0.04	0.03	0.05	0.03
Glutamic acid	15.43	25.49	14.37	6.50	7.06	12.32	5.23	5.69	15.18	19.63
Glutamic acid-d3	-	-	-	-	-	-	-	-	-	-
Glutamine	13.09	15.71	11.08	9.05	7.81	10.66	8.30	6.69	14.82	12.96
Glutathione	10.87	19.29	8.19	6.05	5.60	7.30	4.94	3.54	10.78	10.08
Glutathione disulfide	-	-	-	-	-	-	-	-	-	-
Glutathione-(glycine-13C2,15N)	-	-	-	-	-	-	-	-	-	-
Glycerophosphocholine	203.32	299.60	158.28	98.00	90.93	134.76	110.78	85.85	110.93	103.36
Glycine	0.20	0.25	0.16	0.11	0.11	0.14	0.12	0.10	0.20	0.18
Guanine	0.00	0.01	0.01	0.00	0.01	0.01	0.00	0.01	0.01	0.01
Guanosine	-	-	-	-	-	-	-	-	-	-
Hexanoylcarnitine	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Histamine	4.23	4.94	2.70	-	-	1.01	0.40	0.22	-	-
Histidine	0.16	0.18	0.14	0.11	0.09	0.12	0.10	0.08	0.15	0.13
Homocysteine	1.00	0.73	1.13	0.83	0.66	1.01	0.92	0.81	1.30	1.19
Homoserine	11.73	13.77	9.46	7.05	6.16	8.60	6.98	5.52	12.14	10.48
Hydroxybutyrylcarnitine	0.04	0.04	0.03	0.02	0.02	0.02	0.02	0.02	0.02	0.02
Hydroxyhexanoylcarnitine	0.02	0.03	0.01	0.01	0.01	0.01	0.01	0.01	0.01	0.01
Hydroxyisovaleroyl carnitine	0.10	0.16	0.08	0.06	0.05	0.06	0.04	0.05	0.03	0.04
Hydroxypropionylcarnitine	-	-	-	-	-	-	-	-	-	-
Hypoxanthine	0.08	0.15	0.09	0.07	0.08	0.06	0.06	0.06	0.03	0.03
Imidazoleacetic acid	0.07	0.07	0.07	0.08	0.11	0.06	0.07	0.09	0.06	0.07
Indole	-	-	-	-	-	-	-	-	-	-
Inosine	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Isovalerylcarnitine	0.32	0.49	0.27	0.21	0.19	0.19	0.15	0.16	0.07	0.07
Isovalerylcarnitine-d9	-	-	-	-	-	-	-	-	-	-
Kynurenic acid	0.00	-	0.00	0.01	0.00	0.00	0.01	0.00	0.00	0.00
Kynurenine	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.01
Leucine	0.32	0.39	0.27	0.19	0.17	0.24	0.18	0.16	0.30	0.28
Leucine-d3	-	-	-	-	-	-	-	-	-	-
Linoleyl carnitine	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.01	0.00
LPC(18:1(d7))	-	-	-	-	-	-	-	-	-	-
Lysine	0.02	0.02	0.02	0.01	0.01	0.01	0.01	0.01	0.02	0.01
Mannitol	-	-	-	-	-	-	-	-	-	-
Mannose	0.02	0.02	0.02	0.02	0.01	0.02	0.02	0.01	0.02	0.01
Melatonin	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Methionine	0.09	0.11	0.08	0.05	0.05	0.06	0.05	0.04	0.08	0.07
Methionine-d3	-	-	-	-	-	-	-	-	-	-
Methionine S-oxide	2.28	2.18	1.68	1.48	1.41	1.64	1.68	1.32	2.11	1.50
Methylcobalamin	-	-	-	-	-	-	-	-	-	-
Myristoylcarnitine	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Myristoylcarnitine-d9	-	-	-	-	-	-	-	-	-	-
N15C13-Glycine	-	-	-	-	-	-	-	-	-	-
N1-Acetylspermidine	4.32	5.64	2.39	4.08	3.37	2.46	3.97	3.66	1.96	1.50
N1-Acetylspermidine-d6	-	-	-	-	-	-	-	-	-	-
N1-Acetylspermine	-	-	-	-	-	-	-	-	-	-
N1-N12-Diacetylspermine	0.66	0.49	0.35	0.56	0.47	0.40	0.72	0.59	0.59	0.46
N1-N8-Diacetylspermidine	0.17	0.20	0.12	0.23	0.19	0.17	0.22	0.19	0.12	0.09
N1-N8-Diacetylspermidine-d6	-	-	-	-	-	-	-	-	-	-
N6,N6,N6-Trimethyllysine	0.01	0.01	0.01	0.01	0.01	0.01	0.01	0.00	0.01	0.01
N-Acetylalanine	-	-	-	-	-	-	-	-	-	-
N-Acetylaspartic acid	12.13	16.02	9.65	7.11	6.52	7.45	6.77	6.62	6.58	7.12
N-Acetylcysteine	-	-	-	-	-	-	-	-	-	-
N-Acetylglutamic acid	-	-	-	-	-	-	-	-	-	-
N-Acetylneuraminic acid	-	-	-	-	-	-	-	-	-	-
N-Acetylputrescine	-	-	-	-	-	-	-	-	0.00	-
N-Acetylserine	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
NAD	-	-	-	-	-	-	-	-	-	-
N-Alpha-acetyllysine	-	-	-	-	-	-	-	-	-	-
Niacinamide	0.05	0.05	0.03	0.02	0.02	0.03	0.02	0.02	0.03	0.03
Niacinamide-d4	-	-	-	-	-	-	-	-	-	-
Nicotinamide mononucleotide	-	-	-	-	-	-	-	-	-	-
Nicotinamide riboside	0.01	0.01	0.01	0.01	0.01	0.01	0.01	0.01	0.01	0.01
Nicotinic acid	0.00	-	0.00	-	-	-	-	0.00	0.00	-
Nitrotyrosine	-	-	-	-	-	-	-	-	-	-
N,N^-Bis(gamma-glutamyl)cystine	-	-	-	-	-	-	-	-	-	-
Nonanoylcarnitine	-	-	-	-	-	-	-	-	-	-
Norepinephrine	-	-	-	-	-	-	-	-	-	-
Octanoylcarnitine	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Octanoylcarnitine-d3	-	-	-	-	-	-	-	-	-	-
Ornithine	0.03	0.03	0.03	0.02	0.02	0.02	0.02	0.01	0.03	0.02
Ornithine-d2	-	-	-	-	-	-	-	-	-	-
Palmitoylcarnitine	0.13	0.07	0.07	0.12	0.05	0.07	0.12	0.05	0.09	0.03
Palmitoylcarnitine-d3	-	-	-	-	-	-	-	-	-	-
Paraxanthine	-	-	-	-	-	-	-	-	-	-
Phenylalanine	1.03	1.25	0.83	0.67	0.56	0.75	0.61	0.49	0.93	0.82
Piperanine	-	-	-	-	-	-	-	-	-	-
Piperine	-	-	-	-	-	-	-	-	-	-
Pipernonaline	-	-	-	-	-	-	-	-	-	-
Piperyline	-	-	-	-	-	-	-	-	-	-
Proline	0.51	0.66	0.45	0.30	0.27	0.36	0.30	0.23	0.52	0.42
Propionylcarnitine	0.47	0.67	0.38	0.34	0.33	0.33	0.29	0.27	0.24	0.24
Propionylcartinine-d3	-	-	-	-	-	-	-	-	-	-
Putrescine	-	-	-	-	-	-	-	-	-	-
Pyridoxamine	1.32	1.36	1.09	0.89	0.92	1.01	1.08	0.90	1.34	1.19
Pyroglutamic acid	0.91	1.16	0.86	0.61	0.48	0.74	0.64	0.44	1.01	0.77
S-Adenosylhomocysteine	0.06	0.08	0.04	0.03	0.03	0.04	0.03	0.02	0.05	0.04
S-Adenosylmethionine	0.21	0.27	0.16	0.15	0.12	0.15	0.12	0.10	0.15	0.13
Sarcosine	0.10	0.11	0.08	0.06	0.05	0.07	0.05	0.05	0.09	0.08
Serine	4.60	3.82	3.29	2.52	2.36	3.04	2.59	2.23	3.86	3.21
Serotonin	-	-	-	-	-	-	-	-	-	-
Spermidine	-	-	-	-	-	-	-	-	-	-
Spermine	-	-	-	-	-	-	-	-	-	-
Stearoylcarnitine	0.00	-	-	0.00	-	0.00	0.00	0.00	0.00	0.00
Sucrose	0.34	0.01	0.03	0.35	0.03	0.17	0.37	0.04	0.46	0.03
Taurine	2.58	2.60	2.57	3.06	4.11	2.03	2.94	3.57	2.10	2.68
Tetrahydrocurcumin	-	-	-	-	-	-	-	-	-	-
Theobromine	-	-	-	-	-	-	-	-	-	-
Theophylline	-	-	-	-	-	-	-	-	-	-
Thiamine	0.47	0.74	0.42	0.31	0.27	0.37	0.25	0.25	0.37	0.34
Threonine	6.51	7.85	5.04	3.57	3.03	4.67	3.16	2.62	6.02	5.37
Trigonelline	-	-	-	-	-	-	-	-	-	-
Trimethylamine-d9 N-oxide	-	-	-	-	-	-	-	-	-	-
Trimethylamine-N-oxide	0.01	0.02	0.01	0.01	0.01	0.02	0.01	0.01	0.01	0.01
Tryptophan	0.06	0.07	0.04	0.04	0.04	0.05	0.04	0.03	0.04	0.04
Tyrosine	0.01	0.02	0.01	0.01	0.01	0.01	0.01	0.01	0.01	0.01
Uracil	-	-	-	-	-	-	-	-	-	-
Ureidopropionic acid	0.01	0.01	0.01	0.01	0.00	0.01	0.00	0.00	0.01	0.01
Uric acid	0.08	0.08	0.11	0.07	0.08	0.08	0.09	0.07	0.13	0.08
Uridine	0.00	0.01	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Valerobetaine	0.06	0.08	0.05	0.03	0.03	0.03	0.03	0.02	0.04	0.03
Valerobetaine-d9	-	-	-	-	-	-	-	-	-	-
Valine	0.00	0.01	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Valine-d8	-	-	-	-	-	-	-	-	-	-
Xanthine	0.00	0.00	0.00	0.00	0.00	0.01	0.00	0.00	0.01	0.00
Xanthosine	0.01	0.01	0.01	0.01	0.01	0.01	0.01	0.01	0.01	0.01

Factors:

F1	Genotype:GPR34-KO \| Treatment:Myelin \| Sample source:iMicroglia
F2	Genotype:GPR34 KO \| Treatment:PBS \| Sample source:iMicroglia
F3	Genotype:GPR34-KO \| Treatment:PBS \| Sample source:iMicroglia
F4	Genotype:GPR34/TREM2-KO \| Treatment:Myelin \| Sample source:iMicroglia
F5	Genotype:GPR34/TREM2-KO \| Treatment:PBS \| Sample source:iMicroglia
F6	Genotype:NA \| Treatment:NA \| Sample source:iMicroglia
F7	Genotype:TREM2-KO \| Treatment:Myelin \| Sample source:iMicroglia
F8	Genotype:TREM2-KO \| Treatment:PBS \| Sample source:iMicroglia
F9	Genotype:WT \| Treatment:Myelin \| Sample source:iMicroglia
F10	Genotype:WT \| Treatment:PBS \| Sample source:iMicroglia