Data for ST004223
| Metabolite structure | All data | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 |
|---|---|---|---|---|---|---|---|---|---|
| BMP 18:0_20:4 | 0.14 | 0.17 | 0.13 | 0.15 | 0.10 | 0.11 | 0.11 | 0.11 | |
| BMP 18:1_20:4 | 0.08 | 0.07 | 0.09 | 0.07 | - | - | - | - | |
| BMP 18:1_22:6 | 0.04 | 0.05 | 0.04 | 0.04 | 0.07 | 0.06 | 0.07 | 0.04 | |
| BMP 18:2_20:4, 16:0_22:6 | 0.04 | 0.04 | 0.04 | 0.04 | 0.07 | 0.06 | 0.08 | 0.05 | |
| BMP 20:4_22:6 | 0.10 | 0.10 | 0.10 | 0.09 | - | - | - | - | |
| BMP 22:6_22:6 | 0.38 | 0.42 | 0.42 | 0.40 | 0.42 | 0.41 | 0.43 | 0.37 | |
| CL 18:1/18:1/16:1/16:1 | - | - | - | - | 0.04 | 0.03 | 0.04 | 0.03 | |
| CL 18:1/18:1/18:1/16:0, 18:0/18:1/18:1/16:1 | - | - | - | - | 0.23 | 0.21 | 0.22 | 0.21 | |
| CL 18:1/18:1/18:1/16:1, 18:2/18:1/18:1/16:0 | 0.41 | 0.43 | 0.39 | 0.40 | 0.41 | 0.35 | 0.40 | 0.34 | |
| CL 18:1/18:1/18:1/18:1 | 0.83 | 1.01 | 0.85 | 1.00 | 1.20 | 1.14 | 1.20 | 1.10 | |
| CL 18:1/18:2/18:2/20:2 | 0.74 | 0.83 | 0.72 | 0.77 | 0.52 | 0.50 | 0.52 | 0.47 | |
| CL 18:2/18:1/18:1/16:1, 18:1/18:1/18:1/16:2, 18:2/18:1/18:0/... | 0.17 | 0.17 | 0.18 | 0.16 | 0.17 | 0.14 | 0.18 | 0.14 | |
| CL 18:2/18:1/18:1/18:1 | 0.53 | 0.54 | 0.54 | 0.49 | 0.48 | 0.42 | 0.47 | 0.39 | |
| CL 18:2/18:2/16:1/22:6 | 0.17 | 0.19 | 0.17 | 0.15 | - | - | - | - | |
| CL 18:2/18:2/18:2/16:1 | 0.14 | 0.14 | 0.14 | 0.12 | - | - | - | - | |
| CL 18:2/18:2/18:2/20:2 | 0.61 | 0.68 | 0.60 | 0.61 | 0.73 | 0.69 | 0.72 | 0.66 | |
| CL 18:2/18:2/18:2/20:3 | - | - | - | - | 0.49 | 0.46 | 0.52 | 0.45 | |
| CL 18:2/18:2/18:2/20:4 | 0.54 | 0.59 | 0.51 | 0.51 | 0.20 | 0.20 | 0.24 | 0.19 | |
| CL 18:2/18:2/18:2/22:5, 18:1/18:2/18:2/22:6 | 1.03 | 1.18 | 0.89 | 1.04 | - | - | - | - | |
| CL 18:2/18:2/18:2/22:6 | - | - | - | - | - | - | - | - | |
| CL 18:2/18:2/20:1/22:6, 18:1/18:2/20:2/22:6 | 0.14 | 0.16 | 0.13 | 0.15 | 0.09 | 0.09 | 0.09 | 0.08 | |
| CL 18:2/18:2/20:2/22:6, 18:1/18:2/20:3/22:6 | 0.93 | 1.10 | 0.86 | 1.03 | 0.50 | 0.49 | 0.49 | 0.47 | |
| CL 18:2/18:2/20:3/22:6 | 0.48 | 0.57 | 0.49 | 0.55 | - | - | - | - | |
| CL 18:2/18:2/20:4/22:6 | 0.22 | 0.25 | 0.24 | 0.25 | - | - | - | - | |
| CL 18:2/18:2/22:6/22:6 | 0.10 | 0.12 | 0.12 | 0.12 | - | - | - | - | |
| CL 18:2/18:3/20:4/22:6 | 0.07 | 0.09 | 0.08 | 0.07 | - | - | - | - | |
| CL 20:4/18:1/16:1/16:0, 18:2/18:2/18:1/16:1 | 0.11 | 0.12 | 0.12 | 0.11 | 0.08 | 0.08 | 0.11 | 0.07 | |
| CL 20:4/18:1/18:1/16:0, 20:3/18:1/18:1/16:1, 20:3/18:1/18:1/... | 0.40 | 0.41 | 0.38 | 0.38 | 0.30 | 0.28 | 0.32 | 0.26 | |
| CL 20:4/18:1/18:1/18:0, 20:3/18:1/18:1/18:1 | - | - | - | - | 0.13 | 0.11 | 0.13 | 0.10 | |
| CL 20:4/18:2/18:1/16:0, 20:4/18:1/18:1/16:1 | 0.73 | 0.78 | 0.67 | 0.70 | 0.51 | 0.49 | 0.58 | 0.47 | |
| CL 20:4/18:2/18:1/16:1 | 0.30 | 0.32 | 0.30 | 0.28 | 0.25 | 0.27 | 0.44 | 0.28 | |
| CL 20:4/20:4/18:1/18:1 | 0.47 | 0.53 | 0.47 | 0.48 | 0.49 | 0.48 | 0.50 | 0.45 | |
| CL 20:4/20:4/22:6/22:5, 18:2/22:6/22:6/22:5 | 0.14 | 0.18 | 0.17 | 0.22 | - | - | - | - | |
| CL 22:6/18:1/18:1/18:1, 20:4/20:3/18:1/18:1 | 0.58 | 0.68 | 0.58 | 0.60 | 0.66 | 0.64 | 0.64 | 0.61 | |
| LysoCL 18:1/18:1/18:1 | 0.01 | 0.02 | 0.02 | 0.02 | 0.05 | 0.05 | 0.05 | 0.04 | |
| LysoCL18:1/18:1/22:6 | 0.01 | 0.01 | 0.02 | 0.02 | 0.03 | 0.04 | 0.03 | 0.03 | |
| LysoCL18:2/18:2/20:3, 18:2/18:1/20:4 | 0.01 | 0.01 | 0.01 | 0.01 | 0.02 | 0.02 | 0.02 | 0.02 | |
| PA16:0/16:0 | 0.08 | 0.12 | 0.08 | 0.10 | 0.16 | 0.17 | 0.16 | 0.17 | |
| PA 16:0/16:1 | 0.03 | 0.06 | 0.03 | 0.05 | 0.15 | 0.15 | 0.16 | 0.15 | |
| PA 16:0/18:1 | 0.70 | 1.29 | 0.63 | 1.09 | 3.44 | 4.41 | 3.37 | 4.16 | |
| PA 16:0/18:2 | 0.04 | 0.07 | 0.04 | 0.06 | 0.17 | 0.19 | 0.16 | 0.18 | |
| PA 18:0/18:1 | 0.66 | 1.25 | 0.55 | 1.05 | 2.15 | 3.04 | 2.03 | 2.80 | |
| PA 18:0/18:2, 18:1/18:1 | 0.22 | 0.44 | 0.20 | 0.36 | 1.13 | 1.72 | 1.16 | 1.65 | |
| PA 18:0/20:1 | 0.05 | 0.11 | 0.04 | 0.09 | 0.40 | 0.62 | 0.39 | 0.57 | |
| PA 18:0/20:2 | 0.04 | 0.11 | 0.03 | 0.08 | 0.40 | 0.75 | 0.42 | 0.72 | |
| PA 18:0/20:4 | 0.27 | 0.49 | 0.22 | 0.37 | 1.24 | 1.59 | 1.22 | 1.48 | |
| PA 18:0/22:4 | 0.04 | 0.09 | 0.03 | 0.06 | 0.13 | 0.19 | 0.12 | 0.18 | |
| PA P18:0/20:4 | - | - | - | - | 0.08 | 0.10 | 0.08 | 0.09 | |
| PG 16:0/16:0 | 0.11 | 0.12 | 0.13 | 0.12 | 0.23 | 0.22 | 0.23 | 0.23 | |
| PG 16:0/18:1 | 0.72 | 0.67 | 0.74 | 0.70 | 0.96 | 0.90 | 0.99 | 0.87 | |
| PG 18:0/18:1 | 0.37 | 0.24 | 0.38 | 0.30 | 0.12 | 0.12 | 0.12 | 0.10 | |
| PG 18:1/18:1 | 0.24 | 0.22 | 0.26 | 0.24 | 0.33 | 0.27 | 0.35 | 0.27 | |
| PG 18:2/18:2 | 0.14 | 0.14 | 0.15 | 0.13 | 0.06 | 0.06 | 0.07 | 0.06 | |
| PI 16:0/16:0 | 0.08 | 0.08 | 0.08 | 0.09 | 0.18 | 0.17 | 0.18 | 0.16 | |
| PI 16:0/16:1 | 0.04 | 0.03 | 0.03 | 0.03 | - | - | - | - | |
| PI 16:0/18:1 | 5.83 | 4.62 | 5.51 | 4.96 | 2.03 | 2.03 | 2.15 | 1.98 | |
| PI 16:0/18:2 | 0.12 | 0.10 | 0.11 | 0.11 | 0.11 | 0.10 | 0.10 | 0.09 | |
| PI 16:0/20:4 | 1.10 | 0.99 | 1.20 | 1.04 | - | - | - | - | |
| PI 16:1/20:4 | 0.03 | 0.02 | 0.03 | 0.02 | 1.13 | 1.08 | 1.11 | 1.06 | |
| PI 18:0/18:1 | 0.20 | 0.29 | 0.23 | 0.33 | 0.25 | 0.30 | 0.27 | 0.29 | |
| PI 18:0/18:2 | 0.06 | 0.08 | 0.07 | 0.09 | 0.21 | 0.25 | 0.22 | 0.23 | |
| PI 18:0/20:4 | 6.03 | 5.46 | 5.87 | 5.53 | 4.58 | 4.76 | 4.53 | 4.51 | |
| PI 18:0/22:4 | 0.03 | 0.04 | 0.03 | 0.05 | 0.06 | 0.08 | 0.06 | 0.07 | |
| PI 18:0/22:6 | 0.21 | 0.22 | 0.27 | 0.29 | 0.89 | 0.91 | 0.91 | 0.88 | |
| PI 18:1/20:4 | 1.00 | 0.86 | 1.00 | 0.90 | 0.89 | 1.02 | 0.91 | 0.99 | |
| PI 18:1/22:6 | 0.03 | 0.02 | 0.03 | 0.03 | 0.09 | 0.09 | 0.09 | 0.09 | |
| PI 18:2/20:4, 16:0-22:6 | - | - | - | - | 0.74 | 0.73 | 0.74 | 0.72 | |
| PI P18:0/20:4 | 0.18 | 0.17 | 0.23 | 0.22 | 0.07 | 0.07 | 0.08 | 0.06 | |
| PS 16:0/18:1 | 1.06 | 1.02 | 0.94 | 0.90 | 1.38 | 1.35 | 1.42 | 1.32 | |
| PS 18:0/18:1 | 12.35 | 18.54 | 11.35 | 18.38 | 41.86 | 46.69 | 42.06 | 44.31 | |
| PS 18:0/18:2 | 2.81 | 3.46 | 2.89 | 3.30 | 11.02 | 12.69 | 11.38 | 12.23 | |
| PS 18:0/20:1 | 0.75 | 1.23 | 0.64 | 1.19 | 6.43 | 8.29 | 6.55 | 8.13 | |
| PS 18:0/20:2 | 0.26 | 0.45 | 0.23 | 0.45 | 2.17 | 3.02 | 2.31 | 3.01 | |
| PS 18:0/20:4 | 2.78 | 3.72 | 2.55 | 3.66 | 4.76 | 5.09 | 5.06 | 4.92 | |
| PS 18:0/22:6 | 31.83 | 32.35 | 30.53 | 27.85 | 10.59 | 10.57 | 10.62 | 10.43 | |
| PS 18:1/20:4 | 0.23 | 0.28 | 0.21 | 0.26 | 0.69 | 0.78 | 0.74 | 0.75 | |
| PS 18:1/22:6 | 0.62 | 0.61 | 0.57 | 0.54 | 0.36 | 0.39 | 0.39 | 0.38 | |
| PS 18:2/20:4 | 0.19 | 0.17 | 0.16 | 0.13 | - | - | - | - | |
| PS 20:0/20:1, 18:0/22:1 | 0.45 | 0.47 | 0.34 | 0.45 | 2.35 | 2.52 | 2.35 | 2.38 | |
| PS 20:0/20:2, 18:0/22:2 | 0.31 | 0.46 | 0.27 | 0.45 | 1.35 | 1.75 | 1.38 | 1.68 | |
| PS 20:0/20:4, 18:0/22:4 | 2.65 | 3.20 | 2.19 | 2.76 | 2.11 | 2.49 | 2.07 | 2.38 | |
| PS 20:0/22:1 | 0.22 | 0.19 | 0.17 | 0.19 | - | - | - | - | |
| PS 20:0/22:2 | 0.23 | 0.28 | 0.20 | 0.28 | 1.10 | 1.24 | 1.10 | 1.13 | |
| PS 20:0/22:4 | 0.10 | 0.15 | 0.09 | 0.15 | 0.29 | 0.33 | 0.32 | 0.32 | |
| PS 20:1/22:6 | 0.06 | 0.08 | 0.06 | 0.08 | 0.15 | 0.20 | 0.17 | 0.20 | |
| PS 22:4/22:0 | - | - | - | - | 0.18 | 0.29 | 0.18 | 0.34 | |
| PS 22:6/22:6 | 0.34 | 0.38 | 0.36 | 0.39 | 1.38 | 1.29 | 1.34 | 1.30 | |
| PS P18:0/18:1 | - | - | - | - | 0.51 | 0.46 | 0.56 | 0.46 | |
| PS P18:0/18:2 | - | - | - | - | 0.31 | 0.31 | 0.33 | 0.30 | |
| SHexCer 18:0;O2/24:0 | - | - | - | - | 0.62 | 0.78 | 0.60 | 0.85 | |
| SHexCer 18:1;O2/22:0 | 0.28 | 0.60 | 0.23 | 0.59 | 1.63 | 1.97 | 1.53 | 2.05 | |
| SHexCer 18:1;O2/22:0;O | 0.76 | 1.74 | 0.72 | 1.65 | 1.10 | 1.49 | 1.08 | 1.63 | |
| SHexCer 18:1;O2/22:1;O | 0.11 | 0.28 | 0.10 | 0.26 | 0.81 | 1.00 | 0.78 | 1.04 | |
| SHexCer 18:1;O2/23:0 | 0.21 | 0.40 | 0.17 | 0.39 | 0.82 | 1.01 | 0.78 | 1.05 | |
| SHexCer 18:1;O2/24:0 | 0.69 | 1.54 | 0.61 | 1.55 | 3.84 | 4.56 | 3.56 | 4.72 | |
| SHexCer 18:1;O2/24:0;O | 0.66 | 1.57 | 0.70 | 1.64 | 1.05 | 1.40 | 1.03 | 1.49 | |
| SHexCer 18:1;O2/24:1 | 3.29 | 7.71 | 2.94 | 7.62 | 12.46 | 16.65 | 12.41 | 16.65 | |
| SHexCer 18:1;O2/24:2 | 0.20 | 0.49 | 0.19 | 0.47 | 0.76 | 0.92 | 0.72 | 0.82 | |
| SHexCer 18:1;O2/24:2;O | 0.04 | 0.10 | 0.04 | 0.09 | 0.37 | 0.48 | 0.36 | 0.48 | |
| SHexCer 18:1;O2/25:0, 18:1;O2/24:1;O | 0.76 | 1.89 | 0.74 | 1.85 | 1.04 | 1.46 | 1.06 | 1.57 | |
| SHexCer 18:1;O2/25:1 | 0.14 | 0.33 | 0.13 | 0.33 | 0.37 | 0.49 | 0.36 | 0.48 | |
| SHexCer 18:1;O2/25:1;O | 0.04 | 0.10 | 0.03 | 0.10 | - | - | - | - |
Factors:
| F1 | Sample source:mouse cerebrum | genotype:Cre+ |
| F2 | Sample source:mouse cerebrum | genotype:Cre- |
| F3 | Sample source:mouse cerebrum | genotype:Trem2 KO/Cre+ |
| F4 | Sample source:mouse cerebrum | genotype:Trem2 KO/Cre- |
| F5 | Sample source:mouse spinal cord | genotype:Cre+ |
| F6 | Sample source:mouse spinal cord | genotype:Cre- |
| F7 | Sample source:mouse spinal cord | genotype:Trem2 KO/Cre+ |
| F8 | Sample source:mouse spinal cord | genotype:Trem2 KO/Cre- |