Metabolomics Workbench : NIH Data Repository : Analyze Studies

Data for ST004297

(Analysis AN007144): Average values per metabolite and experimental factor (Units:median-scaled values (batch normalized total ion counts))

Metabolite structure	F1	F2
1-methyl-4-imidazoleacetate	1.53	1.53
1-methyl-5-imidazoleacetate	4.73	3.42
1-methylguanidine	4.64	3.41
1-methylnicotinamide	2.03	2.08
1-methylurate	2.26	2.07
1-ribosyl-imidazoleacetate*	1.94	1.72
2-amino-4-cyanobutanoate	1.49	1.50
2-aminoheptanoate	1.44	1.44
(2-butoxyethoxy)acetic acid	1.44	1.14
2-furoylcarnitine	2.83	2.52
2-hydroxyglutarate	1.57	1.18
2-methylbutyrylcarnitine (C5)	1.59	1.47
2-methylmalonylcarnitine (C4-DC)	1.41	1.33
2-methylserine	1.37	1.23
2^-O-methylcytidine	1.11	1.09
2-oxoarginine*	1.61	1.54
2-piperidinone	6.41	2.33
2-pyrrolidinone	1.72	1.28
3-amino-2-piperidone	1.07	1.26
3-aminoisobutyrate	2.33	2.37
3-(cystein-S-yl)acetaminophen*	1.97	2.72
3-formylindole	1.21	1.11
3-hydroxybutyroylglycine**	2.09	2.08
3-hydroxyhexanoylcarnitine (1)	1.71	1.15
3-hydroxyindolin-2-one	2.32	1.17
3-hydroxykynurenine	1.63	1.37
3-hydroxyoctanoylcarnitine (1)	1.53	1.30
3-hydroxyoctanoylcarnitine (2)	1.49	1.20
3-hydroxyquinine	1.32	0.68
3-hydroxystachydrine*	4.05	2.43
3-methoxytyrosine	1.32	1.09
3-methylcrotonylglycine	1.58	1.55
3-methylcytidine	1.19	1.01
3-methylglutarylcarnitine (2)	2.63	2.27
3-phosphoglycerate	1.66	1.89
4-acetamidobutanoate	2.12	1.75
4-guanidinobutanoate	2.04	1.52
4-hydroxyglutamate	1.39	2.00
4-hydroxyphenylacetoylcarnitine	2.23	2.04
4-imidazoleacetate	1.95	1.21
5-(galactosylhydroxy)-lysine	1.36	1.44
5-hydroxylysine	1.16	1.44
5-hydroxyvalproate	1.31	1.34
5-methylthioadenosine (MTA)	1.53	1.89
5-methylthioribose**	1.45	1.49
6-aminocaproate	2.73	1.00
7-methylurate	1.99	1.46
7-methylxanthine	2.70	1.16
abacavir	1.12	2.41
acetoacetate	3.39	2.81
acetylcarnitine (C2)	1.36	1.00
adenine	1.34	1.67
adenosine 5^-monophosphate (AMP)	1.24	1.81
adipoylcarnitine (C6-DC)	1.93	1.63
alanine	1.30	1.19
alliin	3.66	1.31
alpha-hydroxymetoprolol	5.75	1.82
anthranilate	1.95	1.87
argininate*	1.78	1.43
arginine	0.89	1.16
asparagine	1.17	1.20
aspartate	0.96	1.34
atenolol	8.53	3.08
baclofen	0.75	1.32
benzoylcarnitine*	1.91	9.82
benzoylecgonine	11.50	0.41
beta-alanine	1.16	1.12
beta-guanidinopropanoate	1.72	1.42
beta-hydroxyisovaleroylcarnitine	1.59	1.29
betaine	1.30	1.15
butyrylcarnitine (C4)	2.02	1.34
caffeine	4.65	2.22
carboxyethyl-GABA	1.45	1.35
carnitine	1.12	0.99
cefazolin	5.28	15.06
ceftazidime	1.00	-
choline	1.08	1.24
choline phosphate	1.27	1.21
cis-urocanate	2.59	5.18
citramalate	1.66	1.20
citrulline	1.09	1.13
cotinine	2.47	1.27
creatine	1.19	1.34
creatinine	1.17	1.06
cyclo(gly-pro)	4.27	16.62
cyclo(leu-pro)	1.51	2.42
cyclo(met-pro)	1.62	2.98
cyclo(pro-val)	1.40	1.39
cys-gly, oxidized	2.20	1.29
cystathionine	2.20	2.63
cysteine	1.59	1.03
cysteine s-sulfate	1.06	1.21
cysteine sulfinic acid	1.28	1.07
cysteinylglycine	1.78	1.39
cysteinylglycine disulfide*	1.29	0.99
cystine	1.20	0.98
cytidine 5^-monophosphate (5^-CMP)	3.37	1.73
cytosine	1.94	1.38
deoxycarnitine	1.20	1.08
dexpanthenol	10.47	14.83
dimethylarginine (SDMA + ADMA)	1.17	1.11
dimethylglycine	1.29	1.19
dimethylguanidino valeric acid (DMGV)*	2.48	1.77
dimethyl sulfone	3.36	1.86
doxylamine	3.65	2.38
ectoine	1.70	1.36
emtricitabine	0.92	1.23
ergothioneine	1.69	1.18
ethyl alpha-glucopyranoside	4.48	3.27
formiminoglutamate	4.62	4.71
fosfomycin	3.03	1.00
fructosyllysine	1.10	1.37
gamma-carboxyglutamate	1.50	1.47
gamma-glutamyl-2-aminobutyrate	1.65	1.19
gamma-glutamylalanine	1.46	1.26
gamma-glutamyl-alpha-lysine	1.24	1.34
gamma-glutamylcitrulline*	1.58	0.93
gamma-glutamylglutamate	1.47	1.07
gamma-glutamylglutamine	1.52	0.94
gamma-glutamylglycine	1.41	1.39
gamma-glutamylhistidine	1.66	1.54
gamma-glutamylisoleucine*	1.04	1.43
gamma-glutamylleucine	1.09	1.21
gamma-glutamylmethionine	1.46	1.31
gamma-glutamylphenylalanine	1.43	1.34
gamma-glutamylthreonine	1.19	1.49
gamma-glutamyltryptophan	1.20	1.17
gamma-glutamylvaline	1.18	1.29
glutamate	1.06	1.30
glutamate, gamma-methyl ester	1.05	1.11
glutamine	1.17	1.10
glutarylcarnitine (C5-DC)	1.38	1.43
glycerol 3-phosphate	2.67	1.34
glycerophosphoethanolamine	1.19	1.40
glycerophosphorylcholine (GPC)	1.03	1.35
glycine	1.20	1.25
glycylproline	2.82	0.89
glycylvaline	1.46	1.23
guanidinoacetate	1.23	1.15
HEPES	1.78	-
hexanoylcarnitine (C6)	1.57	1.14
histidine betaine (hercynine)*	1.31	1.21
homoarginine	1.18	1.15
homostachydrine*	2.21	1.44
hydroxyasparagine**	1.33	1.24
hydroxybupropion	3.19	3.77
hydroxycotinine	1.91	1.22
hydroxy-N6,N6,N6-trimethyllysine*	1.40	1.57
hypotaurine	1.45	1.38
imidazole lactate	1.96	2.17
imidazole propionate	2.53	3.94
iminodiacetate (IDA)	1.18	1.21
indoleacetoylcarnitine*	1.52	1.58
indolelactate	1.41	1.27
indolin-2-one	2.50	1.90
inosine 5^-monophosphate (IMP)	2.14	3.32
isobutyrylcarnitine (C4)	2.19	1.41
isoleucine	0.91	1.10
isoleucylhydroxyproline*	1.26	1.45
isovalerylcarnitine (C5)	1.55	1.22
kynurenine	1.35	1.35
lamivudine	0.77	4.01
lamotrigine	0.88	1.29
lanthionine	1.37	1.53
leucine	0.97	1.10
leucylalanine	1.99	1.84
leucylglycine	1.15	1.39
leucylhydroxyproline*	1.53	1.32
levulinoylcarnitine	1.77	1.06
lidocaine	4.02	0.96
lysine	1.04	1.14
metformin	5.51	3.18
methionine	1.19	1.35
methionine sulfone	1.32	1.46
methionine sulfoxide	1.55	1.66
methyl indole-3-acetate	1.77	1.94
methylsuccinoylcarnitine	2.62	2.68
metoclopramide	0.89	1.36
metoprolol	4.86	4.69
metoprolol acid metabolite*	9.08	3.71
mirtazapine	1.40	0.79
N1-methyladenosine	1.09	1.12
N1-methylinosine	1.71	1.79
N1,N12-diacetylspermine	3.08	2.53
(N(1) + N(8))-acetylspermidine	2.21	1.76
N2-acetyl,N6-methyllysine	1.45	1.30
N2-acetyl,N6,N6-dimethyllysine	2.61	2.01
N2,N2-dimethylguanosine	1.72	1.88
N6-carboxymethyllysine	1.45	1.06
N6-methyladenosine	1.23	1.03
N6-methyllysine	1.51	1.27
N6,N6-dimethyllysine	1.39	1.24
N6,N6,N6-trimethyllysine	1.08	1.35
N-acetyl-1-methylhistidine*	2.09	2.04
N-acetyl-2-aminoadipate	1.56	1.67
N-acetylalliin	4.08	2.21
N-acetylarginine	1.28	1.33
N-acetyl-aspartyl-glutamate (NAAG)	1.36	1.50
N-acetylglucosamine/N-acetylgalactosamine	1.27	1.18
N-acetylglucosaminylasparagine	1.54	0.99
N-acetylglycine	1.34	1.25
N-acetylhistidine	1.69	1.40
N-acetyl-isoputreanine	1.58	1.53
N-acetylproline	1.47	1.28
N-acetylputrescine	1.84	1.50
N-acetyltheanine	1.64	1.52
N-alpha-acetylornithine	1.49	1.27
N-carbamoylalanine	1.99	1.40
N-ethylglycinexylidide	2.44	1.82
nicotinamide	1.45	1.34
nicotinamide riboside	1.59	1.72
N-methyl-GABA	1.45	1.57
N-methylhydroxyproline**	22.13	23.58
N-methylpipecolate	1.85	1.53
N-methylproline	3.14	1.69
N,N-dimethyl-5-aminovalerate	2.57	2.78
N,N-dimethylalanine	1.69	1.48
N,N-dimethyl-pro-pro	1.50	1.17
N,N,N-trimethyl-5-aminovalerate	1.46	1.10
N,N,N-trimethyl-alanylproline betaine (TMAP)	1.80	1.36
norcotinine	1.50	0.81
norfentanyl	5.57	2.89
O-desmethyltramadol	4.05	1.31
O-desmethyltramadol glucuronide	2.73	1.69
O-desmethylvenlafaxine	1.17	1.60
ondansetron	3.80	1.56
ornithine	1.04	1.27
oxindolylalanine	1.00	1.30
oxycodone	13.46	7.23
phentermine	1.00	-
phenylacetylcarnitine	2.15	1.41
phenylacetylglutamine	2.60	2.27
phenylalanine	1.18	1.10
phenylephrine	1.60	1.10
phosphate	1.17	1.02
phosphoethanolamine	1.53	1.27
picolinate	2.15	2.02
pimeloylcarnitine/3-methyladipoylcarnitine (C7-DC)	1.89	1.62
pipecolate	1.62	1.42
pro-hydroxy-pro	1.26	1.67
proline	1.13	1.16
prolylglycine	1.12	1.20
propionylcarnitine (C3)	1.57	1.24
pyridoxal	1.05	1.07
quinine	77.49	56.53
(R)-3-hydroxybutyrylcarnitine	2.52	1.42
ranitidine	7.81	6.07
ranitidine N-oxide*	7.18	16.31
ritalinic acid	0.54	1.65
rocuronium	7.40	1.83
S-1-pyrroline-5-carboxylate	1.35	1.40
(S)-3-hydroxybutyrylcarnitine	1.84	1.15
(S)-a-amino-omega-caprolactam	1.53	1.55
sarcosine	1.07	1.06
S-carboxyethylcysteine	1.25	8.26
S-carboxymethyl-cysteine	1.32	1.61
serine	0.96	1.17
serotonin	2.11	1.68
S-methylcysteine sulfoxide	1.59	1.00
S-methylmethionine	4.62	3.58
spermidine	1.69	1.19
stachydrine	3.38	2.29
suberoylcarnitine (C8-DC)	1.83	1.66
succinylcarnitine (C4-DC)	1.24	1.27
theanine	6.66	7.82
theobromine	6.33	2.69
thiamin (vitamin B1)	288.51	178.39
thioproline	1.16	0.95
threonine	1.06	1.30
tigloylglycine	1.37	1.46
tiglylcarnitine (C5:1-DC)	1.70	1.53
tramadol	5.04	1.17
trans-4-hydroxyproline	1.55	1.86
trans-urocanate	9.92	23.25
trazodone	3.99	2.50
triamterene	5.80	8.27
trigonelline (N^-methylnicotinate)	5.41	1.45
trimethylamine N-oxide	2.75	1.75
trizma acetate	4.86	1.60
tryptophan	0.99	1.11
tryptophan betaine	2.75	2.03
tyrosine	1.09	1.18
urea	1.33	1.30
valine	1.00	1.12
valylglycine	1.31	1.31
valylleucine	3.08	1.45
X-11787	1.27	1.21
X-11795	1.96	1.64
X-12096	2.27	1.83
X-12100	1.66	1.63
X-12101	2.68	2.36
X-12112	1.83	1.37
X-12117	2.77	2.17
X-12127	3.30	2.02
X-12199	2.50	2.29
X-12283	2.76	2.65
X-12462	1.37	1.45
X-12680	1.87	2.18
X-12689	1.95	2.17
X-12798	1.42	1.07
X-13507	2.05	2.14
X-13684	2.40	1.05
X-14056	2.96	1.25
X-15161	1.13	1.16
X-15461	1.75	1.42
X-16397	1.64	1.43
X-16580	1.84	1.60
X-17301	5.38	3.12
X-17304	1.37	2.47
X-17306	8.09	-
X-17323	1.44	1.07
X-17325	1.38	1.54
X-17346	1.40	1.23
X-21283	1.25	1.37
X-22162	1.35	1.18
X-23581	1.24	1.09
X-23583	1.35	0.87
X-23587	2.49	2.14
X-23593	1.50	1.64
X-23636	1.04	1.03
X-23639	2.01	1.18
X-23644	3.64	1.55
X-23648	2.03	3.48
X-23654	1.51	1.22
X-23655	2.69	1.35
X-23657	1.44	1.14
X-23659	1.68	1.55
X-23662	2.82	2.67
X-23665	1.54	1.62
X-23666	1.62	1.54
X-23739	1.14	1.54
X-23780	1.61	1.04
X-23997	1.04	1.01
X-24243	1.44	1.36
X-24408	1.24	1.19
X-24410	1.63	1.18
X-24411	1.66	0.91
X-24422	1.80	1.53
X-24425	1.09	1.35
X-24456	1.50	1.65
X-24457	1.86	6.24
X-24462	1.38	1.25
X-24473	1.87	1.20
X-24475	2.30	1.42
X-24518	2.49	1.96
X-24519	1.49	1.79
X-24522	3.86	2.62
X-24531	1.71	1.53
X-24728	1.45	1.59
X-24757	1.68	1.25
X-24763	1.31	1.32
X-24764	3.12	3.68
X-24801	1.21	1.11
X-24812	2.27	1.81
X-24970	1.14	1.04
X-24971	5.04	3.82
X-25044	1.13	1.09
X-25109	4.09	1.70
X-25172	1.02	1.19
X-25265	1.03	0.76
X-25267	1.09	1.13
X-25271	11.08	8.69
X-25343	1.84	1.34
X-25417	4.62	3.19
X-25419	2.45	1.73
X-25420	1.73	1.29
X-25422	2.00	1.99
X-25519	1.35	1.24
X-25520	2.19	1.18
X-25790	1.90	2.28
X-25810	1.61	1.27
X-25948	3.48	1.92
X-25957	1.18	1.13
X-25983	2.09	1.30
X-26008	1.50	1.26
X-26058	1.43	1.01
X-26097	1.27	1.43
X-26235	7.88	7.41
xanthurenate	1.94	2.06
zolpidem	1.32	0.52

Factors:

F1	Timepoint:Day 0 \| Sample source:plasma
F2	Timepoint:Day 2 \| Sample source:plasma