Data for ST004468
| Metabolite structure | All data | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 | F13 | F14 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2.hydroxyglutarate | - | - | - | - | - | - | - | 3172981562.33 | 3089698085.00 | 2385514286.33 | 3321722092.00 | 1545987997.00 | 3168725310.67 | 3572300603.33 | |
| 2.oxobutyric_acid | - | - | - | - | - | - | - | 75853605.60 | 63997240.38 | 49983410.20 | 56163061.91 | 59446288.35 | 64517597.38 | 80636827.66 | |
| 3.phosphoglycerate | 23669879.02 | 12857461.21 | 5631018.02 | 5552793.11 | 4523610.72 | 17999714.25 | 9751548.31 | 5953976.88 | 4511917.20 | 6038119.38 | 6628004.37 | 5532585.78 | 3414813.70 | 2869754.12 | |
| 3.ureidopropionate | 225842505.67 | 257928173.53 | 185218584.40 | 247072580.70 | 204194330.00 | 223773226.63 | 246330714.50 | 76014297.71 | 64361717.38 | 49089634.40 | 56529851.69 | 57376422.72 | 64245692.43 | 78257089.86 | |
| acetylcarnitine | - | - | - | - | - | - | - | 27651914.02 | 18506186.72 | 19780161.36 | 16546121.46 | 26414562.13 | 22438256.98 | 27418758.77 | |
| Acetyl.CoA | - | - | - | - | - | - | - | 4334003.14 | 8510397.75 | 4528498.26 | 2566504.70 | 5062086.79 | 6994026.98 | 5634853.77 | |
| acetylglutamate | - | - | - | - | - | - | - | 14509784.78 | 13032063.90 | 8813007.75 | 12675755.32 | 9704535.19 | 13259065.21 | 11615994.15 | |
| acetylserine | - | - | - | - | - | - | - | 9096243.19 | 16014808.93 | 9805311.59 | 5393644.37 | 10737840.41 | 8952095.32 | 12449218.66 | |
| adenine | - | - | - | - | - | - | - | 248245292.30 | 244916684.27 | 226731745.43 | 133437593.63 | 188822906.43 | 218393523.87 | 291086134.93 | |
| ADP | 16048396.17 | 22634361.26 | 22353756.87 | 4868740.02 | 21885831.76 | 37298061.09 | 29714342.86 | 37317262.67 | 56548479.81 | 53983982.12 | 30177847.74 | 51261631.39 | 58141742.88 | 57832273.55 | |
| AICAR | 1191192.48 | 233890.54 | 1343985.19 | 102001.43 | 2525252.44 | 1768754.73 | 321156.92 | 278454.94 | 127506.40 | 451994.74 | 223594.17 | 2196127.88 | 1266280.40 | 114590.13 | |
| alanine | - | - | - | - | - | - | - | 28701358.05 | 20829594.68 | 21497365.12 | 31062514.63 | 25597022.19 | 22943816.38 | 21787493.50 | |
| AMP | - | - | - | - | - | - | - | 6603850.68 | 8177132.47 | 11894060.06 | 8683917.42 | 9383499.19 | 8032251.90 | 7138167.81 | |
| arginine | 1108764050.30 | 769114476.60 | 651484762.50 | 882901363.57 | 810565129.27 | 887698926.33 | 1152765306.33 | 1910704414.67 | 1785816802.67 | 1347624049.00 | 1561438557.33 | 1267374831.67 | 1824368227.67 | 1899035392.00 | |
| argininosuccinate | - | - | - | - | - | - | - | 5946735.40 | 8783167.31 | 8503552.68 | 5521516.28 | 7114725.55 | 8914015.90 | 8927402.10 | |
| asparagine | 225699624.20 | 258272218.27 | 185572180.80 | 247254674.47 | 204323609.63 | 223805312.07 | 246475007.03 | 846471023.07 | 799987889.17 | 591707909.87 | 677826655.80 | 565994435.70 | 889721409.57 | 900947588.60 | |
| aspartate | 273405189.90 | 149660511.20 | 18425307.80 | 15927850.07 | 16319907.64 | 396227936.53 | 340335227.67 | 80053055.79 | 64359112.53 | 18412357.68 | 24249609.72 | 17522758.46 | 122496990.07 | 108445212.06 | |
| asymmetric.dimethylarginine (ADMA) | 915398.16 | 581739.01 | 1564966.87 | 2777058.48 | 1588856.13 | 1104543.98 | 744335.54 | - | - | - | - | - | - | - | |
| ATP | 78624596.52 | 124014259.67 | 105700429.70 | 28252464.30 | 101124729.96 | 150753955.37 | 166128554.43 | 226033671.50 | 303406002.37 | 224397754.80 | 138659073.43 | 221135310.43 | 310569216.30 | 291995420.27 | |
| beta.alanine | - | - | - | - | - | - | - | 8291863.43 | 6640463.45 | 6736703.58 | 8433434.07 | 6651575.11 | 7170602.95 | 8183129.05 | |
| Butyrylcarnitine | 45779075.15 | 46436109.93 | 10029367.89 | 4054727.61 | 9186979.17 | 51492628.27 | 55673059.13 | 30507121.11 | 37242452.41 | 35785547.75 | 17597720.92 | 37037100.74 | 34338390.58 | 38401867.08 | |
| carnitine | - | - | - | - | - | - | - | 92488756.24 | 112711656.43 | 141355443.47 | 119432736.10 | 134067163.57 | 118191063.33 | 101332567.33 | |
| CDP | 3649137.84 | 2057714.56 | 778869.11 | 1331009.05 | 800201.95 | 3808252.72 | 1975810.57 | 3226639.45 | 3149321.71 | 2829453.59 | 2642982.54 | 2608962.42 | 3776028.39 | 3805314.95 | |
| citrate | - | - | - | - | - | - | - | 116403899.51 | 115272831.10 | 30680122.07 | 27274631.19 | 26045809.74 | 152757808.07 | 140371822.97 | |
| CMP | 466913.77 | 386344.53 | 380878.17 | 586675.63 | 365020.21 | 556029.14 | 304110.56 | 235642.68 | 158841.09 | 418056.17 | 420954.99 | 303271.46 | 291606.86 | 237392.40 | |
| creatine | 1908477608.33 | 1739580896.67 | 1832909306.00 | 2678503852.67 | 1933479627.67 | 1386975456.67 | 2189327376.33 | 103139075.28 | 134240956.03 | 136145936.53 | 163068999.53 | 148374544.07 | 120279584.93 | 106145789.48 | |
| CTP | 16330336.60 | 6370342.63 | 1397647.88 | 4179341.98 | 1586031.18 | 14982486.29 | 7708335.87 | 27003559.65 | 21315577.22 | 14204360.32 | 19714916.10 | 14336818.82 | 24298860.47 | 22463837.23 | |
| cystathionine | - | - | - | - | - | - | - | 4800061.85 | 2624635.90 | 3431715.81 | 3518785.46 | 2562986.02 | 4902744.06 | 4840116.47 | |
| dihydroorotate | 803330.07 | 1595683.27 | 38175241.61 | 17189456.28 | 42525548.90 | 1109518.46 | 1762364.26 | 957779.50 | 2751762.97 | 19482266.87 | 6008557.77 | 20510625.72 | 711914.89 | 1325350.13 | |
| dihydroxyacetone_phosphate | - | - | - | - | - | - | - | 1069676.51 | 840125.99 | 2924467.16 | 5738932.82 | 2360170.00 | 399007.08 | 273179.64 | |
| D.RIBOSE.5.PHOSPHATE | 769726.32 | 746536.79 | 2815148.76 | 3274888.98 | 2753718.40 | 592124.18 | 582243.15 | 2385199.42 | 1825043.60 | 2295016.52 | 4162396.75 | 2027264.77 | 1232949.54 | 1571043.38 | |
| Fructose.1.6.bisphosphate | - | - | - | - | - | - | - | 2235513.57 | 2509374.31 | 3515590.57 | 4956733.10 | 3390848.76 | 2141462.10 | 2298348.09 | |
| Fructose-6-phosphate/Glucose-1-phosphate/Glucose-6-phosphate | 1677100.97 | 775189.99 | 1737562.15 | 2008102.33 | 1621127.50 | 951445.11 | 736884.63 | 1713702.92 | 2110105.44 | 4858353.25 | 5011695.73 | 4954704.34 | 1398785.19 | 1249388.62 | |
| fumarate | - | - | - | - | - | - | - | 14637779.84 | 21955156.68 | 20110812.72 | 10945008.39 | 17236040.66 | 19045436.01 | 19509990.82 | |
| gamma.aminobutyric_acid | - | - | - | - | - | - | - | 18958447.17 | 19995165.87 | 22729562.05 | 20818558.80 | 21472166.22 | 27126761.66 | 22760103.69 | |
| GDP | 1063704.77 | 1124317.40 | 2055415.35 | 1648919.47 | 2029571.31 | 2033777.44 | 1027218.38 | 5029925.70 | 6152730.05 | 6662414.96 | 4664845.00 | 6301114.73 | 6382236.44 | 6311554.18 | |
| Glucose.6.phosphate | 1684223.19 | 726153.94 | 1835828.87 | 2018962.15 | 1491907.41 | 830370.60 | 737080.64 | 551147.94 | 620953.33 | 743779.83 | 764052.92 | 691408.54 | 592156.00 | 486454.00 | |
| glutamate | - | - | - | - | - | - | - | 1710462158.00 | 1855553001.33 | 1181705469.33 | 1240692670.67 | 1198482606.67 | 1845395741.00 | 1704723478.33 | |
| glutamine | 3220154243.00 | 4304286862.00 | 2962440909.00 | 3940443909.33 | 3220531008.00 | 3570105233.00 | 4167895926.67 | 7396221841.00 | 6844948942.33 | 5238017579.00 | 6066352190.33 | 4784408826.67 | 7410987491.00 | 7052410072.67 | |
| Glycerol.3.Phosphate | 2472654.06 | 9585043.57 | 124960339.90 | 135631285.07 | 125489664.57 | 4203634.10 | 4190664.64 | 22889083.43 | 34896774.60 | 104327780.77 | 125027320.13 | 99589812.80 | 13625168.16 | 13109833.78 | |
| Glycerophosphocholine | - | - | - | - | - | - | - | 2278416748.33 | 3346331020.33 | 1886702320.67 | 1790026123.33 | 2285001486.33 | 3344486751.00 | 2836849121.67 | |
| glycine | 27634263.89 | 29972901.35 | 26191176.55 | 27066413.08 | 22379567.22 | 24605656.72 | 25733738.01 | 13381979.96 | 11133059.34 | 8870817.43 | 12909050.66 | 9301841.83 | 12068084.07 | 12121021.72 | |
| GMP | 241755.64 | 447422.70 | 2332007.32 | 3186376.85 | 1978181.56 | 459399.42 | 422071.14 | 1082014.18 | 1017337.85 | 1718636.62 | 1501677.33 | 1503770.47 | 1063108.41 | 1059783.67 | |
| GSH_Ellmans | 324424668.60 | 395533582.53 | 369142120.63 | 369198254.70 | 360373465.73 | 395781868.93 | 371653729.77 | 469742863.70 | 481636459.07 | 438349874.73 | 415971457.80 | 432603605.00 | 439264656.40 | 418116410.03 | |
| GSSG | - | - | - | - | - | - | - | 5242634.55 | 5063504.53 | 5798769.01 | 4927482.30 | 5768391.40 | 5224091.89 | 4186902.65 | |
| GTP | 5376681.33 | 5446844.79 | 7494505.56 | 3893245.49 | 7675825.94 | 11335324.00 | 5860568.60 | 19413362.54 | 21857944.32 | 20360162.84 | 17447627.05 | 20898475.03 | 21666474.20 | 20705322.56 | |
| guanidinoacetate | 13442472.02 | 11155081.53 | 19393633.23 | 34469770.88 | 20662972.89 | 9723005.21 | 15983735.55 | - | - | - | - | - | - | - | |
| guanine | - | - | - | - | - | - | - | 13859295.94 | 19141760.92 | 16636127.27 | 9284802.51 | 14275947.60 | 13875079.72 | 21196877.58 | |
| histidine | - | - | - | - | - | - | - | 219814433.77 | 219686649.77 | 185756007.07 | 243131478.50 | 174538519.20 | 213904884.07 | 208442077.60 | |
| hypotaurine | 10450313.57 | 13909205.45 | 11341690.44 | 17734004.92 | 12495448.59 | 11854159.84 | 12593198.75 | - | - | - | - | - | - | - | |
| hypoxanthine | 2678734.64 | 7258030.76 | 2510400.20 | 3558778.19 | 2253768.57 | 2848996.85 | 4429227.88 | - | - | - | - | - | - | - | |
| IMP | 2943374.23 | 2033117.05 | 38820652.56 | 3993080.06 | 37833973.22 | 1547631.47 | 1125152.31 | 1456279.06 | 519690.18 | 6606567.53 | 3894387.00 | 5656111.56 | 614711.59 | 324229.63 | |
| isoleucine | 241651530.40 | 288856096.97 | 282961035.40 | 307608468.23 | 251697419.93 | 178658752.33 | 292634133.10 | 484844801.20 | 456561915.50 | 297653412.57 | 333945430.03 | 393608397.93 | 280087331.93 | 398119838.87 | |
| Itaconic.Acid | 3022540443.00 | 5936827132.67 | 2550860640.33 | 2514369038.33 | 3137469246.33 | 3467383514.67 | 3044403185.67 | - | - | - | - | - | - | - | |
| leucine | 311778521.70 | 415692228.57 | 340303454.87 | 465403618.60 | 344185650.17 | 262803779.10 | 378923561.67 | - | - | - | - | - | - | - | |
| lysine | 18879889.51 | 13547194.11 | 18746972.65 | 19863009.84 | 18266778.95 | 14446845.80 | 13777579.89 | 26425302.71 | 23050538.66 | 17913037.66 | 21866125.64 | 16240390.68 | 23456032.10 | 25664260.31 | |
| malate | 412949237.17 | 652646908.80 | 271544864.37 | 161925248.73 | 314551300.73 | 672064207.63 | 723955670.17 | - | - | - | - | - | - | - | |
| methionine | 101985115.51 | 162741128.53 | 120681345.16 | 135624820.97 | 113583709.68 | 88924397.60 | 147623537.27 | - | - | - | - | - | - | - | |
| Methionine.sulfoxide | 87161565.21 | 129341601.60 | 83005407.31 | 96070022.72 | 96340131.56 | 76327171.50 | 133353750.30 | 138338740.27 | 181666526.87 | 132795372.69 | 133142092.73 | 124538139.50 | 159415093.10 | 155379816.80 | |
| methylthioadenosine | - | - | - | - | - | - | - | 6665578.78 | 7414021.80 | 6247512.47 | 2460152.12 | 7710842.74 | 5808257.56 | 7541236.51 | |
| myo.inositol | 162009027.40 | 142185937.67 | 208528147.90 | 238039281.93 | 190276074.37 | 242184283.10 | 232823777.13 | 270099595.20 | 238823400.43 | 291374032.77 | 298644920.67 | 284057752.57 | 269506560.67 | 255578969.47 | |
| N.acetylglutamine | 127224303.31 | 137116049.05 | 80934964.91 | 140566779.77 | 90081089.00 | 94508251.92 | 167551621.10 | 10641731.44 | 11665776.62 | 8174954.69 | 11324617.63 | 8301078.18 | 11991620.40 | 9942147.72 | |
| NAD | 108493090.43 | 179609345.67 | 76058275.07 | 99242350.57 | 78297896.90 | 117201854.97 | 142009358.83 | 200504670.47 | 206511751.03 | 137829324.83 | 147239852.27 | 124619272.60 | 197571819.70 | 177257194.87 | |
| NADH | - | - | - | - | - | - | - | 10417511.94 | 14597417.52 | 22242107.13 | 22185412.50 | 19792095.42 | 11500560.02 | 11474872.71 | |
| NADP | - | - | - | - | - | - | - | 1617006.35 | 2225299.23 | 1508718.10 | 1310231.76 | 1455273.43 | 1908050.10 | 1820006.11 | |
| NADPH | 1701846.50 | 2471884.86 | 1362640.71 | 1334096.35 | 1576680.16 | 2241773.06 | 2329704.55 | 4637932.06 | 4260157.98 | 3633015.58 | 3734974.52 | 2694559.14 | 4659433.23 | 4501471.22 | |
| niacinamide | - | - | - | - | - | - | - | 56517934.02 | 59049730.98 | 46518028.59 | 30530796.85 | 58068943.62 | 35188616.38 | 41532774.97 | |
| ornithine | - | - | - | - | - | - | - | 13987412.86 | 14121244.77 | 9872267.43 | 12164083.11 | 9338392.78 | 14352261.15 | 18211229.53 | |
| palmitate | - | - | - | - | - | - | - | 102077335.01 | 56731683.86 | 47471778.58 | 40388174.90 | 69100877.44 | 51998223.05 | 128642550.22 | |
| phosphocholine | - | - | - | - | - | - | - | 19538119228.00 | 22109534139.33 | 14595382419.67 | 11614024981.00 | 13930176863.67 | 23878707491.33 | 22460529413.00 | |
| phosphocreatine | 1729853.95 | 1835862.06 | 3204317.31 | 2457285.78 | 3186578.14 | 2244156.49 | 2308432.69 | - | - | - | - | - | - | - | |
| phosphoenolpyruvate | 8848261.88 | 4339958.21 | 644378.19 | 874535.56 | 599541.55 | 5654690.15 | 3934872.91 | 1208971.59 | 612049.18 | 726178.23 | 989421.82 | 632973.42 | 587199.11 | 512344.33 | |
| phosphoethanolamine | - | - | - | - | - | - | - | 1806476.54 | 889086.47 | 1227292.94 | 4499677.75 | 928792.35 | 484790.74 | 453599.70 | |
| proline | - | - | - | - | - | - | - | 1644102577.67 | 3222208630.00 | 1870445310.67 | 1467352381.33 | 2326060039.67 | 2049761006.67 | 2061981088.87 | |
| Pyridoxine | 56817640.82 | 79215258.28 | 49211313.38 | 54665787.78 | 44363907.35 | 56823050.17 | 72723882.94 | 60360939.24 | 60476495.09 | 46057208.22 | 36575633.89 | 59156108.03 | 46647043.96 | 60183073.72 | |
| quinolinic_acid | - | - | - | - | - | - | - | 9591553.60 | 7162936.61 | 5312595.79 | 7252307.97 | 6136894.90 | 7942673.81 | 7326210.75 | |
| saccharopine | 301186.28 | 237763.85 | 7322020.25 | 7969253.44 | 7575015.96 | 428296.49 | 393718.96 | 592903.10 | 497956.67 | 473395.57 | 432574.15 | 322183.80 | 694421.62 | 581937.59 | |
| S.Adenosyl.L.Homocysteine | 3209018.67 | 6550301.72 | 1519865.32 | 1500532.49 | 1953769.37 | 2817038.89 | 4993032.97 | - | - | - | - | - | - | - | |
| S.Adenosyl.L.methionine | 63378182.99 | 74852835.08 | 43262719.08 | 23378210.41 | 45316317.00 | 70443136.63 | 77805535.06 | 129985025.13 | 146245189.70 | 104944117.81 | 99372734.36 | 96760484.90 | 154527443.53 | 152691624.10 | |
| sarcosine | 85915842.57 | 76895530.66 | 45002427.62 | 58336244.31 | 47281437.70 | 101248406.80 | 105493433.30 | - | - | - | - | - | - | - | |
| Sedoheptulose.7.phosphate | 115415.49 | 325134.27 | 2751126.34 | 1191477.63 | 2429903.05 | 291260.56 | 241339.67 | 1824972.98 | 2812799.61 | 8401236.45 | 8231803.87 | 7945699.54 | 1581320.42 | 1550765.03 | |
| serine | 45391872.93 | 51403683.93 | 41166784.20 | 50592051.40 | 44030679.77 | 44447271.98 | 52624512.69 | 100964284.18 | 91459735.26 | 64324964.01 | 88165312.15 | 64110015.07 | 97823126.43 | 108559814.71 | |
| succinate | 89897641.87 | 174301776.30 | 239025939.27 | 133245713.30 | 255155232.17 | 117802613.97 | 91380117.15 | 68625511.58 | 67740345.54 | 62056810.24 | 75543873.93 | 50189999.84 | 71229842.24 | 71844982.17 | |
| taurine | 401865637.37 | 497755243.80 | 463193256.07 | 606326210.80 | 420264564.93 | 488315405.60 | 388761603.47 | - | - | - | - | - | - | - | |
| threonine | 148383580.72 | 227434925.20 | 141789720.80 | 163014163.87 | 130129877.48 | 106558200.41 | 213104376.77 | - | - | - | - | - | - | - | |
| tryptophan | 29033074.63 | 41971865.98 | 32883075.75 | 37588365.80 | 31103397.67 | 24971801.92 | 40089671.19 | - | - | - | - | - | - | - | |
| tyrosine | 102412121.68 | 180265992.63 | 114107427.83 | 124204578.27 | 125701294.54 | 90964378.96 | 145993632.43 | 123859592.04 | 180618213.67 | 143297619.68 | 106849103.03 | 127673475.40 | 135269292.81 | 146577040.13 | |
| UDP | - | - | - | - | - | - | - | 9318411.45 | 7983402.71 | 7869437.14 | 8889669.78 | 7564976.46 | 9434481.36 | 9529301.38 | |
| UDP.GlcNAc | 61208536.60 | 46426072.08 | 6529026.24 | 15572665.59 | 6516272.76 | 57037067.93 | 56422967.74 | 87391118.95 | 74142902.14 | 40485919.26 | 53811754.04 | 35135832.03 | 96148866.64 | 91598895.65 | |
| UDP.hexose | - | - | - | - | - | - | - | 86153727.31 | 67334757.46 | 45008430.78 | 58359812.38 | 41670962.51 | 73583645.35 | 71505712.84 | |
| UMP | 1633180.92 | 884193.06 | 488206.87 | 1749067.31 | 507288.22 | 1331726.00 | 1140298.55 | 1208036.69 | 1363546.23 | 2310175.62 | 3041438.26 | 2130858.97 | 1083680.14 | 1491382.07 | |
| Ureidosuccinic_acid | 1176576.91 | 471999.83 | 249860618.03 | 74265492.47 | 184924880.20 | 2357852.91 | 1609964.31 | 12160899.09 | 20035180.56 | 170494459.70 | 98449367.70 | 171510721.90 | 13078153.09 | 12147193.02 | |
| UTP | 71406712.61 | 25435871.80 | 4135689.36 | 17440922.05 | 4359542.83 | 50816708.11 | 32070402.51 | 102093832.96 | 70704903.82 | 46479409.60 | 76161955.48 | 47031583.36 | 79159986.15 | 70654781.52 |
Factors:
| F1 | Sample source:NALM6 leukemia cells | treatment:6MP |
| F2 | Sample source:NALM6 leukemia cells | treatment:ADDA5 |
| F3 | Sample source:NALM6 leukemia cells | treatment:BCS |
| F4 | Sample source:NALM6 leukemia cells | treatment:BCS+6MP |
| F5 | Sample source:NALM6 leukemia cells | treatment:BCS+MTX |
| F6 | Sample source:NALM6 leukemia cells | treatment:MTX |
| F7 | Sample source:NALM6 leukemia cells | treatment:Vehicle |
| F8 | Sample source:SEM leukemia cells | treatment:6MP |
| F9 | Sample source:SEM leukemia cells | treatment:ADDA5 |
| F10 | Sample source:SEM leukemia cells | treatment:BCS |
| F11 | Sample source:SEM leukemia cells | treatment:BCS+6MP |
| F12 | Sample source:SEM leukemia cells | treatment:BCS+MTX |
| F13 | Sample source:SEM leukemia cells | treatment:MTX |
| F14 | Sample source:SEM leukemia cells | treatment:Vehicle |