Data for ST004494
| Metabolite structure | All data | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 2-phosphoglyceric acid_0 | 297562.75 | 54059.00 | 106592.25 | 66666.67 | 85469.00 | 795031.50 | 114683.67 | 243287.75 | 180347.00 | 187030.33 | |
| 2-phosphoglyceric acid_1 | - | - | - | - | - | - | - | - | - | - | |
| 2-phosphoglyceric acid_2 | 22596.75 | 51728.50 | 4228.00 | 22220.75 | 29158.50 | 43160.75 | 75007.25 | 29859.50 | 20661.75 | 64301.50 | |
| 2-phosphoglyceric acid_3 | 2230529.25 | 4321633.25 | 2013664.00 | 1481181.00 | 2563331.00 | 1548541.25 | 4429952.50 | 1856569.75 | 1591216.25 | 3401024.00 | |
| 3-phosphoglyceric acid_0 | 256764.33 | 36941.00 | 78960.50 | 64472.00 | 48170.00 | 680922.75 | 101277.75 | 225206.25 | 113582.00 | 135511.75 | |
| 3-phosphoglyceric acid_1 | - | - | - | - | - | - | - | - | - | - | |
| 3-phosphoglyceric acid_2 | 14897.75 | 74568.00 | 22424.75 | 22171.25 | 27901.00 | 22246.00 | 50472.25 | 20726.75 | 21666.25 | 54375.75 | |
| 3-phosphoglyceric acid_3 | 1554254.00 | 4241583.25 | 1574922.50 | 1364502.75 | 2326508.75 | 1403558.50 | 4808085.00 | 1589905.50 | 1449914.00 | 3918121.50 | |
| 6-Phosphogluconic acid_0 | 2888432.75 | 1067556.50 | 2786293.50 | 2239504.50 | 1985542.75 | 244662.50 | 141820.00 | 686326.67 | 327628.25 | 262091.50 | |
| 6-Phosphogluconic acid_1 | - | 1501.00 | - | - | - | - | 1.00 | - | - | - | |
| 6-Phosphogluconic acid_2 | - | - | - | - | - | - | 4583.00 | - | - | - | |
| 6-Phosphogluconic acid_3 | - | - | - | - | - | - | 58239.00 | 1.00 | - | - | |
| 6-Phosphogluconic acid_4 | - | 22.75 | 3.00 | 5.75 | 14.50 | - | 63590.50 | 17.50 | 28.00 | 46.67 | |
| 6-Phosphogluconic acid_5 | - | 696238.75 | 11618.00 | 36367.50 | 223257.50 | - | 367667.00 | 32498.67 | 32155.33 | 340108.67 | |
| 6-Phosphogluconic acid_6 | 9009.00 | 4387935.25 | 159057.75 | 539110.50 | 1426333.25 | - | 3816174.00 | 1859304.50 | 2985962.67 | 4607713.33 | |
| Dihydroxyacetone phosphate_0 | 10619975.25 | 4505841.25 | 6067022.75 | 3458548.50 | 2294467.50 | 46523717.50 | 6251739.25 | 5354493.50 | 12219749.00 | 4495010.75 | |
| Dihydroxyacetone phosphate_1 | - | - | - | - | - | - | 48.00 | - | - | - | |
| Dihydroxyacetone phosphate_2 | 25123.25 | 35958.50 | 17015.00 | 3065.50 | 498.00 | - | 1676.00 | 5355.33 | 158.33 | 458.00 | |
| Dihydroxyacetone phosphate_3 | 19771699.00 | 23896748.50 | 15303004.50 | 4775498.25 | 4177320.25 | 377094.50 | 8189347.00 | 14871950.25 | 2117438.00 | 3116882.75 | |
| Erythrose, 4-phosphate_0 | 698140.50 | 233379.33 | 485870.50 | 317136.33 | 237463.50 | 707191.50 | 299715.25 | 498151.00 | 332562.25 | 280794.50 | |
| Erythrose, 4-phosphate_1 | - | - | - | - | - | - | - | - | - | - | |
| Erythrose, 4-phosphate_2 | - | - | - | - | - | - | - | - | - | - | |
| Erythrose, 4-phosphate_3 | 97176.50 | 196596.25 | 81958.00 | 170393.25 | 146053.25 | 213115.25 | 70441.50 | 227841.25 | 123763.75 | 73725.00 | |
| Erythrose, 4-phosphate_4 | 192673.50 | 321806.50 | 207650.25 | 243336.50 | 242376.75 | 184796.25 | 246976.50 | 216076.00 | 181616.00 | 232231.75 | |
| Fructose-1,6-bisphosphate_0 | 7735738.75 | 4063653.50 | 4735683.50 | 3707288.00 | 2876932.50 | 44116964.00 | 8934239.00 | 6059219.25 | 13481060.50 | 8472944.00 | |
| Fructose-1,6-bisphosphate_1 | - | - | - | 5075.00 | - | - | 7927.00 | - | - | - | |
| Fructose-1,6-bisphosphate_2 | - | - | - | - | - | - | - | - | - | - | |
| Fructose-1,6-bisphosphate_3 | 120968.25 | 11136.00 | 119622.00 | 41988.50 | 3860.00 | - | 20.00 | 143933.00 | 79552.33 | 36623.33 | |
| Fructose-1,6-bisphosphate_4 | 52190.00 | 15054.00 | 6322.00 | - | 168.50 | - | 159.75 | 4826.00 | 46.00 | 27.00 | |
| Fructose-1,6-bisphosphate_5 | 442813.25 | 1182897.25 | 459877.67 | 230941.25 | 246355.50 | - | 181665.50 | 385198.50 | 315828.00 | 122702.50 | |
| Fructose-1,6-bisphosphate_6 | 19858980.25 | 26625982.75 | 17219779.50 | 11900403.00 | 11637058.25 | 131193.00 | 9112440.50 | 19287909.75 | 9178413.75 | 6847156.50 | |
| Fructose-6-phosphate_0 | 1762967.75 | 407022.75 | 1115297.50 | 708912.75 | 426314.75 | 2572771.50 | 438402.50 | 1400320.25 | 600349.75 | 339054.75 | |
| Fructose-6-phosphate_1 | 30002.00 | - | 25722.00 | - | - | 24330.00 | - | 21939.50 | 20211.00 | - | |
| Fructose-6-phosphate_2 | - | - | - | - | - | - | - | - | - | - | |
| Fructose-6-phosphate_3 | 131965.25 | 53913.25 | 53768.00 | 62688.75 | 59596.00 | 166346.00 | 42450.33 | 100684.00 | 85650.25 | 21152.00 | |
| Fructose-6-phosphate_4 | - | 23048.00 | - | - | - | 29756.00 | 26.00 | - | - | 27.33 | |
| Fructose-6-phosphate_5 | 191204.75 | 482972.25 | 215510.25 | 255099.50 | 289584.50 | 136068.25 | 392982.25 | 205061.75 | 226260.25 | 257042.50 | |
| Fructose-6-phosphate_6 | 4375548.75 | 10380331.75 | 5237689.00 | 6029502.75 | 6990287.50 | 3352562.50 | 8227068.25 | 4751496.75 | 5194824.75 | 6040662.00 | |
| Glucose 6-phosphate_0 | 5079814.00 | 4191242.75 | 4231741.50 | 3708850.50 | 3494932.50 | 5879829.00 | 3895087.75 | 4820210.25 | 4519968.50 | 3885305.25 | |
| Glucose 6-phosphate_1 | - | 30098.00 | 18941.00 | 41744.00 | 25514.00 | 70442.33 | 16953.67 | 22067.00 | 14463.00 | 28211.50 | |
| Glucose 6-phosphate_2 | - | - | - | - | - | - | - | - | - | - | |
| Glucose 6-phosphate_3 | 311745.75 | 237203.00 | 215608.75 | 280802.75 | 209247.25 | 393027.25 | 98268.25 | 332943.50 | 301865.00 | 160072.75 | |
| Glucose 6-phosphate_4 | 42765.75 | 41209.00 | 25551.50 | 55938.25 | 27011.75 | 46511.50 | 15222.00 | 51369.50 | 48890.25 | 13419.00 | |
| Glucose 6-phosphate_5 | 401536.00 | 811004.50 | 419466.50 | 552198.25 | 600621.50 | 287060.25 | 538792.75 | 429382.50 | 475175.00 | 540401.50 | |
| Glucose 6-phosphate_6 | 7927604.50 | 16486567.25 | 8574836.50 | 11695435.50 | 12402020.50 | 5537400.25 | 11063193.25 | 8593753.00 | 9228094.75 | 11578218.00 | |
| Lactic acid_0 | 774437716.00 | 166474224.50 | 434609335.75 | 344034390.75 | 263635829.75 | 236948735.25 | 160477847.25 | 634579582.00 | 376303971.50 | 427620724.25 | |
| Lactic acid_1 | 2445817.75 | 3021991.75 | 1506760.75 | 2935336.25 | 1530028.50 | - | 2291905.50 | 2572831.75 | 1633657.00 | 2987601.33 | |
| Lactic acid_2 | 6302993.00 | 28993658.00 | 7809929.75 | 15059402.00 | 15119102.25 | 4561778.00 | 19296757.75 | 6211326.75 | 7751394.25 | 9030904.50 | |
| Lactic acid_3 | 235356197.00 | 1043556367.25 | 268339249.75 | 492015388.25 | 541863414.75 | 43647991.00 | 675900298.50 | 198679120.50 | 254488819.00 | 307620566.75 | |
| Phosphoenolpyruvic acid_0 | 25796.00 | - | 8817.50 | - | - | 71074.00 | - | 15059.00 | - | - | |
| Phosphoenolpyruvic acid_1 | - | - | - | - | - | - | - | - | - | - | |
| Phosphoenolpyruvic acid_2 | 1.00 | 1.50 | 91.25 | 1.00 | 1.00 | 1.00 | 76.50 | 30191.00 | 1.00 | 1.00 | |
| Phosphoenolpyruvic acid_3 | 402937.00 | 725320.75 | 370774.25 | 294478.00 | 348918.00 | 266159.50 | 742289.25 | 222378.50 | 358219.50 | 509105.25 | |
| Pyruvic acid_0 | 2275588.75 | 970125.00 | 939492.75 | 884827.50 | 832934.75 | 4122728.75 | 1201481.00 | 3347033.50 | 823481.75 | 2289391.25 | |
| Pyruvic acid_1 | 25059.00 | 32645.00 | 29035.00 | 37802.33 | 63905.00 | 53597.50 | 25561.00 | 39488.00 | 46370.50 | 17018.00 | |
| Pyruvic acid_2 | 43024.00 | 40069.00 | - | - | - | - | 37857.33 | - | - | 30885.00 | |
| Pyruvic acid_3 | 2739980.75 | 3698844.50 | 2603383.00 | 1618365.75 | 2870812.00 | 1883254.00 | 2667710.75 | 1024373.50 | 987509.00 | 2107869.50 | |
| Ribose 5-phosphate_0 | 1940700.25 | 112552.75 | 704274.25 | 584946.25 | 224355.75 | 2598030.00 | 186499.00 | 380834.00 | 666946.25 | 349270.75 | |
| Ribose 5-phosphate_1 | - | - | - | - | - | - | - | - | - | - | |
| Ribose 5-phosphate_2 | 54743.00 | - | - | - | - | - | - | - | - | - | |
| Ribose 5-phosphate_3 | 52681.00 | - | - | - | - | - | - | - | - | - | |
| Ribose 5-phosphate_4 | 5.00 | 9477.00 | 4.25 | 7.00 | 7.75 | 3.75 | 9.50 | 3.50 | 5.00 | 7.50 | |
| Ribose 5-phosphate_5 | 1234434.25 | 3913040.00 | 1204074.75 | 1646915.25 | 2369846.00 | 1099520.75 | 2906319.75 | 997125.00 | 1270409.25 | 2130978.75 | |
| Sedoheptulose 7-phosphate_0 | 139191.67 | - | 65184.33 | 10572.00 | - | 146951.25 | - | 63059.50 | - | - | |
| Sedoheptulose 7-phosphate_1 | - | - | - | - | - | - | - | - | - | - | |
| Sedoheptulose 7-phosphate_2 | - | - | - | - | - | 7777.00 | - | - | 1.00 | - | |
| Sedoheptulose 7-phosphate_3 | 28924.25 | - | - | - | - | 71154.00 | - | 20378.00 | 12062.00 | - | |
| Sedoheptulose 7-phosphate_4 | 73528.00 | 21442.00 | 49830.50 | 38451.25 | 37029.33 | 122327.50 | - | 85807.75 | 37719.00 | 19764.00 | |
| Sedoheptulose 7-phosphate_5 | 22802.75 | 20.00 | 12145.00 | 14890.00 | 8156.00 | 27605.75 | 12.50 | 10613.67 | 11741.00 | 12.33 | |
| Sedoheptulose 7-phosphate_6 | 91698.75 | 117637.75 | 92317.00 | 101850.50 | 95609.75 | 98317.00 | 59635.00 | 106522.50 | 68488.33 | 56927.25 | |
| Sedoheptulose 7-phosphate_7 | 1186704.75 | 2110441.50 | 1275322.25 | 1580091.50 | 1666669.75 | 862402.75 | 1313099.50 | 1428897.50 | 1015002.67 | 1285454.25 | |
| Xylulose 5-phosphate_0 | 3615729.00 | - | 1350773.75 | 194707.00 | 29313.25 | 3696504.75 | 1217599.50 | 1733320.00 | 247550.00 | 68908.75 | |
| Xylulose 5-phosphate_1 | - | - | - | - | - | - | - | - | - | - | |
| Xylulose 5-phosphate_2 | - | - | - | - | - | - | - | - | - | - | |
| Xylulose 5-phosphate_3 | - | - | - | - | - | - | - | - | - | - | |
| Xylulose 5-phosphate_4 | - | 3572.25 | 1.00 | 1.00 | 1.00 | - | 6.25 | 2.00 | 1.00 | 1.33 | |
| Xylulose 5-phosphate_5 | 230128.75 | 2048039.25 | 204524.50 | 196400.75 | 383571.25 | 166129.75 | 1911354.50 | 352112.00 | 170072.75 | 362236.25 |
Factors:
| F1 | Genotype:TIGAR-knockout | Treatment:13C Glc | Time:1H | Sample source:HT29 CL.16E cells |
| F2 | Genotype:TIGAR-knockout | Treatment:13C Glc | Time:24H | Sample source:HT29 CL.16E cells |
| F3 | Genotype:TIGAR-knockout | Treatment:13C Glc | Time:2H | Sample source:HT29 CL.16E cells |
| F4 | Genotype:TIGAR-knockout | Treatment:13C Glc | Time:4H | Sample source:HT29 CL.16E cells |
| F5 | Genotype:TIGAR-knockout | Treatment:13C Glc | Time:8H | Sample source:HT29 CL.16E cells |
| F6 | Genotype:Wild-type | Treatment:13C Glc | Time:1H | Sample source:HT29 CL.16E cells |
| F7 | Genotype:Wild-type | Treatment:13C Glc | Time:24H | Sample source:HT29 CL.16E cells |
| F8 | Genotype:Wild-type | Treatment:13C Glc | Time:2H | Sample source:HT29 CL.16E cells |
| F9 | Genotype:Wild-type | Treatment:13C Glc | Time:4H | Sample source:HT29 CL.16E cells |
| F10 | Genotype:Wild-type | Treatment:13C Glc | Time:8H | Sample source:HT29 CL.16E cells |
