Metabolomics Workbench : NIH Data Repository : Analyze Studies

Data for ST001411

(Analysis AN002361): Average values per metabolite and experimental factor (Units:Peak area)

Metabolite structure	F1	F2	F3
10-heptadecenoate (17:1n7)	1.38	1.25	0.92
10-hydroxywarfarin	0.14	0.16	0.08
10-nonadecenoate (19:1n9)	1.19	1.12	1.02
10-undecenoate (11:1n1)	0.97	1.04	1.11
11beta-hydroxyandrosterone glucuronide	1.05	1.29	0.82
1-(1-enyl-oleoyl)-GPE (P-18:1)*	1.29	1.11	1.55
1-(1-enyl-palmitoyl)-2-arachidonoyl-GPC (P-16:0/20:4)*	0.97	1.05	1.14
1-(1-enyl-palmitoyl)-2-arachidonoyl-GPE (P-16:0/20:4)*	1.02	1.08	1.04
1-(1-enyl-palmitoyl)-2-linoleoyl-GPC (P-16:0/18:2)*	0.98	1.03	1.69
1-(1-enyl-palmitoyl)-2-linoleoyl-GPE (P-16:0/18:2)*	1.01	1.02	1.13
1-(1-enyl-palmitoyl)-2-oleoyl-GPC (P-16:0/18:1)*	1.02	1.07	1.64
1-(1-enyl-palmitoyl)-2-oleoyl-GPE (P-16:0/18:1)*	1.03	1.04	1.10
1-(1-enyl-palmitoyl)-2-palmitoleoyl-GPC (P-16:0/16:1)*	1.09	1.08	1.31
1-(1-enyl-palmitoyl)-2-palmitoyl-GPC (P-16:0/16:0)*	1.01	1.07	1.49
1-(1-enyl-palmitoyl)-GPC (P-16:0)*	1.02	1.02	1.80
1-(1-enyl-palmitoyl)-GPE (P-16:0)*	1.27	1.27	1.18
1-(1-enyl-stearoyl)-2-arachidonoyl-GPE (P-18:0/20:4)*	1.02	1.07	1.09
1-(1-enyl-stearoyl)-2-linoleoyl-GPE (P-18:0/18:2)*	1.01	1.02	1.48
1-(1-enyl-stearoyl)-2-oleoyl-GPE (P-18:0/18:1)	1.04	1.07	1.19
1-(1-enyl-stearoyl)-GPE (P-18:0)*	1.21	1.12	1.70
12,13-DiHOME	0.98	0.99	0.71
1,2,3-benzenetriol sulfate (2)	1.42	1.28	1.00
1,2-dilinoleoyl-GPC (18:2/18:2)	0.98	0.96	1.92
1,2-dilinoleoyl-GPE (18:2/18:2)*	1.25	0.95	0.71
1,2-dipalmitoyl-GPC (16:0/16:0)	1.02	1.01	1.14
(12 or 13)-methylmyristate (a15:0 or i15:0)	1.05	1.09	0.94
1,3,7-trimethylurate	1.20	1.38	0.53
1,3-dimethylurate	1.02	1.11	0.91
13-HODE + 9-HODE	0.97	1.02	0.79
14-HDoHE/17-HDoHE	0.80	0.98	1.64
(14 or 15)-methylpalmitate (a17:0 or i17:0)	1.12	1.09	1.04
1,5-anhydroglucitol (1,5-AG)	0.86	0.99	1.41
16a-hydroxy DHEA 3-sulfate	1.19	1.76	0.71
16-hydroxypalmitate	1.22	1.20	0.92
(16 or 17)-methylstearate (a19:0 or i19:0)	1.07	1.09	1.13
1,7-dimethylurate	0.96	1.07	0.81
1-arachidonoyl-GPC (20:4n6)*	1.24	1.13	1.20
1-arachidonoyl-GPE (20:4n6)*	1.05	1.04	0.96
1-arachidonoyl-GPI (20:4)*	1.12	1.06	1.12
1-arachidonylglycerol (20:4)	1.28	1.23	0.83
1-carboxyethylisoleucine	1.50	1.51	0.31
1-carboxyethylleucine	1.34	1.33	0.36
1-carboxyethylphenylalanine	1.37	1.45	0.37
1-carboxyethyltyrosine	1.21	1.26	0.27
1-carboxyethylvaline	1.40	1.41	0.32
1-dihomo-linolenylglycerol (20:3)	1.17	1.14	0.72
1-docosahexaenoylglycerol (22:6)	1.30	1.23	1.17
1H-indole-7-acetic acid	0.89	0.95	0.88
1-linolenoylglycerol (18:3)	1.16	1.17	1.12
1-linolenoyl-GPC (18:3)*	1.14	1.16	1.40
1-linoleoyl-2-linolenoyl-GPC (18:2/18:3)*	0.93	0.97	2.07
1-linoleoylglycerol (18:2)	1.31	1.09	0.95
1-linoleoyl-GPA (18:2)*	1.02	0.96	1.25
1-linoleoyl-GPC (18:2)	1.01	1.02	1.33
1-linoleoyl-GPE (18:2)*	1.10	1.07	1.44
1-linoleoyl-GPG (18:2)*	1.11	0.99	1.04
1-linoleoyl-GPI (18:2)*	1.18	1.03	1.56
1-methyl-4-imidazoleacetate	1.19	1.26	1.00
1-methyl-5-imidazoleacetate	1.29	1.69	0.96
1-methylhistidine	1.00	1.16	1.21
1-methylnicotinamide	1.32	1.31	1.56
1-methylurate	1.22	1.16	1.12
1-methylxanthine	1.12	1.40	1.01
1-myristoyl-2-arachidonoyl-GPC (14:0/20:4)*	1.02	1.17	0.98
1-myristoyl-2-palmitoyl-GPC (14:0/16:0)	1.07	1.14	1.16
1-oleoyl-2-arachidonoyl-GPE (18:1/20:4)*	1.22	1.06	0.84
1-oleoyl-2-docosahexaenoyl-GPC (18:1/22:6)*	0.98	1.02	1.34
1-oleoyl-2-docosahexaenoyl-GPE (18:1/22:6)*	1.25	1.10	0.82
1-oleoyl-2-linoleoyl-GPE (18:1/18:2)*	1.28	1.10	1.08
1-oleoylglycerol (18:1)	1.37	1.16	0.96
1-oleoyl-GPC (18:1)	1.08	1.08	1.30
1-oleoyl-GPE (18:1)	1.19	1.11	1.19
1-oleoyl-GPG (18:1)*	0.93	0.90	1.13
1-oleoyl-GPI (18:1)	1.15	1.05	1.52
1-oleoyl-GPS (18:1)	0.95	0.97	1.06
1-palmitoleoylglycerol (16:1)*	1.28	1.14	1.25
1-palmitoleoyl-GPC (16:1)*	1.17	1.19	1.17
1-palmitoyl-2-arachidonoyl-GPC (16:0/20:4n6)	1.00	1.03	0.97
1-palmitoyl-2-arachidonoyl-GPE (16:0/20:4)*	1.18	1.09	0.88
1-palmitoyl-2-arachidonoyl-GPI (16:0/20:4)*	1.02	1.09	1.06
1-palmitoyl-2-dihomo-linolenoyl-GPC (16:0/20:3n3 or 6)*	1.00	1.01	1.02
1-palmitoyl-2-docosahexaenoyl-GPC (16:0/22:6)	0.97	1.05	1.22
1-palmitoyl-2-docosahexaenoyl-GPE (16:0/22:6)*	1.12	1.05	0.86
1-palmitoyl-2-linoleoyl-GPC (16:0/18:2)	0.98	0.99	1.19
1-palmitoyl-2-linoleoyl-GPE (16:0/18:2)	1.23	1.10	1.06
1-palmitoyl-2-linoleoyl-GPI (16:0/18:2)	0.87	0.79	1.36
1-palmitoyl-2-oleoyl-GPC (16:0/18:1)	0.99	1.02	1.09
1-palmitoyl-2-oleoyl-GPE (16:0/18:1)	1.26	1.10	0.88
1-palmitoyl-2-oleoyl-GPI (16:0/18:1)*	1.16	1.03	1.54
1-palmitoyl-2-palmitoleoyl-GPC (16:0/16:1)*	1.13	1.11	0.87
1-palmitoyl-2-stearoyl-GPC (16:0/18:0)	0.99	0.98	1.32
1-palmitoyl-2-stearoyl-GPE (16:0/18:0)*	0.81	0.73	0.62
1-palmitoyl-GPA (16:0)	0.70	0.60	1.09
1-palmitoyl-GPC (16:0)	0.98	1.00	1.23
1-palmitoyl-GPE (16:0)	1.08	1.07	1.23
1-palmitoyl-GPG (16:0)*	1.17	1.01	1.04
1-palmitoyl-GPI (16:0)	1.41	1.20	1.75
1-ribosyl-imidazoleacetate*	1.10	1.10	0.87
1-stearoyl-2-arachidonoyl-GPC (18:0/20:4)	1.00	1.05	0.98
1-stearoyl-2-arachidonoyl-GPE (18:0/20:4)	1.12	1.06	0.94
1-stearoyl-2-arachidonoyl-GPI (18:0/20:4)	1.00	1.03	1.19
1-stearoyl-2-arachidonoyl-GPS (18:0/20:4)	1.13	1.11	1.12
1-stearoyl-2-docosahexaenoyl-GPC (18:0/22:6)	0.95	1.05	1.22
1-stearoyl-2-docosahexaenoyl-GPE (18:0/22:6)*	1.12	1.03	0.68
1-stearoyl-2-linoleoyl-GPC (18:0/18:2)*	0.98	0.99	1.23
1-stearoyl-2-linoleoyl-GPE (18:0/18:2)*	1.22	1.10	1.01
1-stearoyl-2-linoleoyl-GPI (18:0/18:2)	1.06	0.98	1.78
1-stearoyl-2-oleoyl-GPC (18:0/18:1)	0.96	0.97	1.13
1-stearoyl-2-oleoyl-GPE (18:0/18:1)	1.29	1.16	0.90
1-stearoyl-2-oleoyl-GPI (18:0/18:1)*	1.05	0.94	1.84
1-stearoyl-2-oleoyl-GPS (18:0/18:1)	1.13	1.08	1.32
1-stearoyl-GPC (18:0)	0.97	1.02	1.29
1-stearoyl-GPE (18:0)	1.17	1.13	1.23
1-stearoyl-GPG (18:0)	0.87	0.72	0.75
1-stearoyl-GPI (18:0)	1.27	1.11	1.40
1-stearoyl-GPS (18:0)*	1.20	1.03	1.13
21-hydroxypregnenolone disulfate	1.01	1.26	1.41
2,3-dihydroxy-2-methylbutyrate	1.07	1.10	0.85
2,3-dihydroxy-5-methylthio-4-pentenoate (DMTPA)*	1.03	1.07	0.98
2,3-dihydroxyisovalerate	3.12	2.99	3.73
(2,4 or 2,5)-dimethylphenol sulfate	1.60	1.51	0.41
2,6-dihydroxybenzoic acid	1.38	1.25	1.43
2-acetamidophenol sulfate	1.35	1.04	1.76
2-aminoadipate	1.08	1.13	0.60
2-aminobutyrate	1.01	1.06	1.06
2-aminoheptanoate	1.20	1.04	0.89
2-aminooctanoate	1.06	1.10	1.45
2-aminophenol sulfate	1.42	1.28	1.51
2-arachidonoylglycerol (20:4)	0.90	1.17	1.12
(2-butoxyethoxy)acetic acid	0.68	0.83	0.56
2^-deoxyuridine	0.92	0.91	1.18
2-ethylphenylsulfate	0.65	0.47	0.18
2-hydroxy-3-methylvalerate	1.31	1.39	1.01
2-hydroxy-4-(methylthio)butanoic acid	1.11	1.22	1.35
2-hydroxyacetaminophen sulfate*	0.75	0.82	0.19
2-hydroxyadipate	1.01	1.29	0.66
2-hydroxybutyrate/2-hydroxyisobutyrate	1.11	1.18	0.77
2-hydroxydecanoate	1.26	1.20	1.09
2-hydroxyglutarate	1.05	1.05	1.20
2-hydroxyhippurate (salicylurate)	62.69	39.58	0.82
2-hydroxyibuprofen	0.61	0.24	0.51
2-hydroxylaurate	1.04	1.07	1.10
2-hydroxynervonate*	1.09	1.10	0.98
2-hydroxyoctanoate	1.08	1.16	1.63
2-hydroxypalmitate	1.05	1.05	1.22
2-hydroxyphenylacetate	1.04	1.21	1.04
2-hydroxysebacate	1.18	1.05	0.82
2-hydroxystearate	1.02	1.06	1.13
2-keto-3-deoxy-gluconate	1.18	1.06	0.98
2-ketocaprylate	1.06	1.14	1.42
2-linoleoylglycerol (18:2)	1.21	1.14	1.44
2-methoxyacetaminophen glucuronide*	0.74	0.69	0.17
2-methoxyacetaminophen sulfate*	0.60	0.82	0.11
2-methylbutyrylcarnitine (C5)	1.04	1.09	0.92
2-naphthol sulfate	1.97	2.56	1.44
2-oleoylglycerol (18:1)	1.34	1.00	1.07
2^-O-methylcytidine	1.00	0.99	1.25
2^-O-methyluridine	2.15	1.53	2.05
(2 or 3)-decenoate (10:1n7 or n8)	1.04	1.12	1.12
2-oxoarginine*	1.20	1.31	0.77
2-palmitoleoyl-GPC (16:1)*	1.14	1.08	1.12
2-palmitoyl-GPC (16:0)*	1.42	1.19	1.53
2-piperidinone	2.76	1.71	1.23
2R,3R-dihydroxybutyrate	1.01	1.11	0.97
2S,3R-dihydroxybutyrate	1.05	1.13	1.07
2-stearoyl-GPE (18:0)*	1.11	1.04	1.38
3-(3-amino-3-carboxypropyl)uridine*	1.07	1.03	0.92
3-(3-hydroxyphenyl)propionate	1.23	1.64	1.26
3-(3-hydroxyphenyl)propionate sulfate	0.69	0.91	0.92
3,4-dihydroxybutyrate	1.13	1.14	0.81
3-(4-hydroxyphenyl)lactate	0.96	1.02	1.10
3,4-methyleneheptanoate	0.91	0.96	1.25
3,5-dichloro-2,6-dihydroxybenzoic acid	1.08	1.28	1.03
3,7-dimethylurate	1.38	1.07	1.48
3-acetylphenol sulfate	1.02	1.10	0.70
3-amino-2-piperidone	1.14	1.07	1.01
3-aminoisobutyrate	1.11	1.12	1.29
3beta-hydroxy-5-cholestenoate	1.03	0.99	1.67
3b-hydroxy-5-cholenoic acid	0.76	0.86	0.89
3-bromo-5-chloro-2,6-dihydroxybenzoic acid*	1.07	1.39	1.22
3-carboxy-4-methyl-5-pentyl-2-furanpropionate (3-CMPFP)**	1.02	1.22	1.38
3-carboxy-4-methyl-5-propyl-2-furanpropanoate (CMPF)	1.05	1.64	1.69
3-(cystein-S-yl)acetaminophen*	0.49	0.53	0.17
3-decenoylcarnitine	0.89	0.95	1.34
3-ethylcatechol sulfate (1)	1.24	1.39	0.82
3-formylindole	0.94	1.11	1.03
3-hydroxy-2-ethylpropionate	1.07	1.15	1.01
3-hydroxy-2-methylpyridine sulfate	1.20	1.28	0.26
3-hydroxy-3-methylglutarate	1.18	1.00	0.62
3-hydroxyadipate*	1.39	1.45	0.62
3-hydroxybutyrate (BHBA)	1.96	1.57	1.36
3-hydroxybutyroylglycine**	1.27	1.23	1.03
3-hydroxycotinine glucuronide	0.47	0.49	0.32
3-hydroxydecanoate	1.28	1.46	0.89
3-hydroxydecanoylcarnitine	1.21	1.17	1.92
3-hydroxydodecanedioate*	2.13	1.72	0.78
3-hydroxyhexanoate	1.18	1.18	0.99
3-hydroxyhexanoylcarnitine (1)	1.05	1.02	1.11
3-hydroxyhippurate	2.38	2.81	2.17
3-hydroxyhippurate sulfate	1.16	1.33	0.81
3-hydroxyindolin-2-one sulfate	1.11	0.99	0.69
3-hydroxyisobutyrate	1.15	1.19	0.83
3-hydroxylaurate	1.10	1.26	1.04
3-hydroxymyristate	1.03	1.15	0.91
3-hydroxyoctanoate	1.58	1.79	0.86
3-hydroxyoleoylcarnitine	1.09	1.01	1.16
3-hydroxyphenylacetoylglutamine	1.02	1.00	0.79
3-hydroxypyridine glucuronide	0.90	1.00	0.16
3-hydroxypyridine sulfate	1.66	1.78	0.86
3-hydroxysebacate	1.77	1.52	0.64
3-hydroxystachydrine*	4.08	3.71	1.39
3-hydroxystearate	1.11	1.00	0.97
3-indoleglyoxylic acid	1.01	0.98	1.23
3-indoxyl sulfate	1.14	1.20	0.91
3-methoxycatechol sulfate (1)	1.47	1.40	0.92
3-methoxycatechol sulfate (2)	0.95	1.04	0.88
3-methoxytyrosine	1.04	1.07	1.32
3-methyl-2-oxobutyrate	1.01	1.07	0.94
3-methyl-2-oxovalerate	0.99	1.07	0.92
3-methyladipate	1.09	1.22	1.41
3-methyl catechol sulfate (1)	1.27	1.56	0.90
3-methyl catechol sulfate (2)	1.01	1.26	0.51
3-methylcytidine	0.91	0.93	1.09
3-methylglutaconate	1.23	1.25	0.73
3-methylglutarylcarnitine (2)	1.15	1.51	0.92
3-methylhistidine	1.67	2.24	1.16
3-(methylthio)acetaminophen sulfate*	0.57	0.65	0.23
3-methylxanthine	1.31	1.27	1.50
3-(N-acetyl-L-cystein-S-yl) acetaminophen	0.51	0.58	0.18
3-phenylpropionate (hydrocinnamate)	1.19	1.32	2.31
3-phosphoglycerate	1.09	1.04	1.17
3-ureidopropionate	1.18	1.09	1.03
4-acetamidobutanoate	1.14	1.12	1.01
4-acetamidophenol	66.54	55.48	14.48
4-acetamidophenylglucuronide	0.97	0.53	0.15
4-acetaminophen sulfate	7.80	6.60	1.45
4-acetylcatechol sulfate (1)	1.30	1.26	1.02
4-acetylphenol sulfate	0.94	0.91	0.93
4-allylcatechol sulfate	1.84	1.43	1.88
4-allylphenol sulfate	1.45	1.23	1.62
4-cholesten-3-one	1.00	0.95	0.93
4-ethylcatechol sulfate	1.44	1.59	1.00
4-ethylphenylsulfate	1.22	1.24	2.30
4-guanidinobutanoate	1.31	1.10	0.91
4-hydroxy-2-oxoglutaric acid	1.08	1.18	0.98
4-hydroxychlorothalonil	1.22	1.15	1.76
4-hydroxycoumarin	1.70	1.22	1.41
4-hydroxyglutamate	1.30	1.30	0.48
4-hydroxyhippurate	1.53	1.30	0.86
4-hydroxyphenylacetate	1.32	1.34	0.66
4-hydroxyphenylacetylglutamine	1.36	1.29	0.70
4-hydroxyphenylpyruvate	1.03	1.04	0.79
4-imidazoleacetate	0.87	0.78	0.63
4-methoxyphenol sulfate	1.27	1.23	1.49
4-methyl-2-oxopentanoate	0.97	1.07	0.92
4-methylbenzenesulfonate	1.00	1.03	1.14
4-methylcatechol sulfate	1.26	1.28	1.94
4-methylguaiacol sulfate	1.63	1.82	2.04
4-methylhexanoylglutamine	1.12	0.87	1.00
4-vinylguaiacol sulfate	0.99	1.41	0.23
4-vinylphenol sulfate	1.18	1.60	1.36
5,6-dihydrothymine	1.05	1.07	1.20
5,6-dihydrouracil	0.77	0.80	1.01
5,6-dihydrouridine	1.07	1.06	0.98
5-acetylamino-6-amino-3-methyluracil	1.01	1.23	0.98
5-acetylamino-6-formylamino-3-methyluracil	1.23	1.65	0.95
5alpha-androstan-3alpha,17beta-diol disulfate	0.96	0.91	1.15
5alpha-androstan-3alpha,17beta-diol monosulfate (1)	1.21	0.90	1.31
5alpha-androstan-3alpha,17beta-diol monosulfate (2)	0.81	0.82	1.14
5alpha-androstan-3beta,17alpha-diol disulfate	0.85	1.06	2.15
5alpha-androstan-3beta,17beta-diol disulfate	1.47	1.65	1.89
5alpha-androstan-3beta,17beta-diol monosulfate (2)	0.96	0.83	1.11
5alpha-pregnan-3beta,20alpha-diol disulfate	1.12	1.34	1.31
5alpha-pregnan-3beta,20alpha-diol monosulfate (2)	1.00	1.16	1.51
5alpha-pregnan-3beta,20beta-diol monosulfate (1)	0.97	0.99	1.45
5-dodecenoate (12:1n7)	1.09	1.13	1.03
5-dodecenoylcarnitine (C12:1)	1.15	1.14	1.38
5-(galactosylhydroxy)-L-lysine	1.01	0.87	0.81
5-hydroxy-2-methylpyridine sulfate	1.19	1.20	0.21
5-hydroxyhexanoate	1.02	0.96	0.73
5-hydroxyindoleacetate	1.04	1.08	0.75
5-hydroxyindole sulfate	0.88	1.01	0.97
5-hydroxylysine	1.16	1.06	0.89
5-methylthioadenosine (MTA)	1.07	1.09	0.86
5-methyluridine (ribothymidine)	1.02	1.01	1.22
5-oxoproline	1.02	1.00	1.08
6-bromotryptophan	0.99	1.08	1.10
6-hydroxyindole sulfate	1.16	1.29	0.98
6-oxopiperidine-2-carboxylate	1.07	1.11	0.71
7-alpha-hydroxy-3-oxo-4-cholestenoate (7-Hoca)	1.16	1.08	0.88
7-hydroxywarfarin	0.46	0.46	0.41
7-methylguanine	1.05	1.01	1.09
7-methylurate	1.19	1.12	1.14
7-methylxanthine	1.43	1.27	1.80
8-methoxykynurenate	0.91	0.97	0.74
acesulfame	0.50	1.61	0.88
acetoacetate	1.37	1.28	1.68
acetylcarnitine (C2)	1.02	1.05	1.13
acisoga	1.09	1.08	0.80
aconitate [cis or trans]	1.01	1.07	0.89
adenine	1.05	1.09	0.73
adenosine	0.83	0.82	0.64
adenosine 5^-diphosphoribose (ADP-ribose)	0.94	1.02	1.30
adenosine 5^-monophosphate (AMP)	1.02	1.01	1.10
adipoylcarnitine (C6-DC)	1.19	1.25	1.14
adrenate (22:4n6)	1.63	1.53	1.05
alanine	1.05	1.09	0.84
allantoin	0.97	0.99	0.97
allopurinol	0.64	0.63	0.63
allopurinol riboside	0.54	0.52	0.52
alpha-hydroxycaproate	1.13	0.89	0.69
alpha-hydroxyisocaproate	1.02	1.11	1.01
alpha-hydroxyisovalerate	1.38	1.48	1.01
alpha-ketobutyrate	1.08	1.16	0.87
alpha-ketoglutaramate*	1.04	1.00	1.10
alpha-ketoglutarate	1.05	1.07	0.76
alpha-tocopherol	1.05	1.01	1.34
androstenediol (3alpha, 17alpha) monosulfate (2)	0.99	1.13	1.22
androstenediol (3alpha, 17alpha) monosulfate (3)	1.21	1.09	1.64
androstenediol (3beta,17beta) disulfate (1)	1.37	1.86	1.43
androstenediol (3beta,17beta) disulfate (2)	0.98	1.18	1.18
androstenediol (3beta,17beta) monosulfate (1)	1.19	1.23	1.29
androstenediol (3beta,17beta) monosulfate (2)	1.23	1.39	1.51
andro steroid monosulfate C19H28O6S (1)*	1.04	1.42	0.64
androsterone glucuronide	1.17	1.25	1.79
androsterone sulfate	1.28	1.09	1.81
anthranilate	1.05	1.01	0.77
arabinose	1.06	0.85	0.76
arabitol/xylitol	1.12	1.09	0.97
arabonate/xylonate	1.18	1.15	1.14
arachidate (20:0)	1.12	1.04	1.13
arachidonate (20:4n6)	1.25	1.21	0.99
arachidonoylcarnitine (C20:4)	1.05	1.06	1.35
arachidonoylcholine	1.53	1.50	1.43
arachidoylcarnitine (C20)*	0.97	1.05	2.10
argininate*	1.12	1.08	0.98
arginine	0.97	0.99	1.29
ascorbic acid 2-sulfate	1.08	1.10	1.00
ascorbic acid 3-sulfate*	0.97	1.02	0.97
asparagine	0.99	1.01	1.08
aspartate	1.04	1.08	0.95
atenolol	0.44	0.46	0.43
azelate (C9-DC)	1.18	1.21	1.04
behenoylcarnitine (C22)*	0.91	0.95	1.39
behenoyl dihydrosphingomyelin (d18:0/22:0)*	1.05	1.11	1.06
behenoyl sphingomyelin (d18:1/22:0)*	0.99	1.03	1.31
benzoate	1.24	1.13	1.12
benzoylcarnitine*	0.94	0.86	1.29
beta-alanine	1.03	1.02	0.93
beta-citrylglutamate	1.02	1.07	1.05
beta-cryptoxanthin	1.21	1.29	2.77
beta-hydroxyisovalerate	0.99	1.10	0.92
beta-hydroxyisovaleroylcarnitine	1.01	1.03	1.03
betaine	1.04	0.98	1.09
bilirubin (E,E)*	1.11	1.05	1.80
bilirubin (E,Z or Z,E)*	0.98	1.07	1.55
bilirubin (Z,Z)	0.98	1.05	1.52
biliverdin	1.04	1.05	1.94
branched chain 14:0 dicarboxylic acid**	1.15	1.39	2.27
branched-chain, straight-chain, or cyclopropyl 10:1 fatty ac...	1.18	1.21	1.14
branched-chain, straight-chain, or cyclopropyl 10:1 fatty ac...	0.88	0.92	0.83
branched-chain, straight-chain, or cyclopropyl 10:1 fatty ac...	0.72	0.70	0.84
branched-chain, straight-chain, or cyclopropyl 12:1 fatty ac...	1.08	1.14	1.10
butyrate (4:0)	1.05	1.06	0.89
butyrylcarnitine (C4)	1.14	1.33	1.39
butyrylglycine	0.88	0.80	0.83
caffeic acid sulfate	1.99	2.44	0.33
caffeine	1.34	1.44	0.95
campesterol	1.06	1.23	2.02
caprate (10:0)	1.14	1.35	0.91
caproate (6:0)	1.16	1.52	1.09
caprylate (8:0)	1.15	1.28	0.88
carboxyethyl-GABA	0.98	1.00	0.92
carboxyibuprofen	16.00	8.95	13.11
carnitine	0.95	1.01	1.08
carnitine of C10H14O2 (5)*	1.08	1.11	0.93
carotene diol (1)	1.11	1.12	2.37
carotene diol (2)	1.15	1.16	2.43
carotene diol (3)	0.94	1.25	2.50
catechol sulfate	1.09	1.09	1.43
ceramide (d16:1/24:1, d18:1/22:1)*	0.98	1.05	1.18
ceramide (d18:1/14:0, d16:1/16:0)*	1.09	1.02	1.17
ceramide (d18:1/17:0, d17:1/18:0)*	0.99	1.00	1.06
ceramide (d18:1/20:0, d16:1/22:0, d20:1/18:0)*	1.01	1.03	1.21
ceramide (d18:2/24:1, d18:1/24:2)*	0.97	1.05	1.50
cerotoylcarnitine (C26)*	0.97	1.12	1.67
cetirizine	0.99	0.99	0.99
C-glycosyltryptophan	1.11	1.08	1.06
chenodeoxycholate	1.56	1.54	1.15
chenodeoxycholic acid sulfate (1)	1.08	1.18	0.57
cholate	4.21	3.63	2.93
cholesterol	0.99	1.04	1.49
choline	1.04	1.00	0.97
choline phosphate	1.01	1.03	1.10
cinnamoylglycine	1.50	1.04	2.10
cis-4-decenoate (10:1n6)*	1.09	1.05	1.16
cis-4-decenoylcarnitine (C10:1)	1.04	1.01	1.28
cis-urocanate	1.01	1.07	0.87
citalopram N-oxide*	0.42	0.43	0.41
citalopram propionate*	0.45	0.44	0.43
citraconate/glutaconate	1.77	1.80	0.85
citramalate	1.10	1.10	0.96
citrate	0.97	1.03	1.08
citrulline	0.95	0.94	1.24
cortisol	1.02	0.99	1.31
cortisone	0.94	0.96	1.16
cortolone glucuronide (1)	1.00	1.14	0.78
cotinine	0.16	0.23	0.04
cotinine N-oxide	0.42	0.42	0.29
creatine	1.11	1.17	0.88
creatinine	0.98	1.03	1.11
cys-gly, oxidized	1.04	1.02	1.24
cystathionine	1.40	1.74	0.86
cysteine	1.09	1.15	1.10
cysteine-glutathione disulfide	0.89	0.87	0.97
cysteine s-sulfate	1.16	1.13	1.04
cysteine sulfinic acid	1.04	1.06	0.82
cysteinylglycine	1.09	1.06	1.06
cysteinylglycine disulfide*	0.99	1.02	1.09
cystine	1.05	1.11	1.01
cytidine	1.47	1.26	0.77
cytosine	1.09	1.32	0.62
decadienedioic acid (C10:2-DC)**	1.12	1.32	1.15
decanoylcarnitine (C10)	1.05	1.04	1.44
dehydroepiandrosterone sulfate (DHEA-S)	1.06	1.19	1.37
deoxycarnitine	0.98	1.00	1.27
deoxycholate	1.48	1.50	0.48
deoxycholic acid (12 or 24)-sulfate*	1.71	1.89	0.42
deoxycholic acid glucuronide	1.46	1.41	1.30
desmethylcitalopram*	0.78	0.75	0.75
desmethylnaproxen	1.00	1.00	1.00
desmethylnaproxen sulfate	1.00	1.00	1.00
dexlansoprazole	0.57	0.51	0.17
diacylglycerol (14:0/18:1, 16:0/16:1) [1]*	1.34	1.05	0.54
diacylglycerol (14:0/18:1, 16:0/16:1) [2]*	1.64	1.32	0.68
diacylglycerol (16:1/18:2 [2], 16:0/18:3 [1])*	1.30	1.14	0.93
didesmethylcitalopram*	0.31	0.28	0.28
dihomo-linoleate (20:2n6)	1.26	1.20	1.03
dihomo-linolenate (20:3n3 or n6)	1.18	1.14	0.90
dihomo-linolenoylcarnitine (C20:3n3 or 6)*	1.02	1.04	1.32
dihomo-linolenoyl-choline	1.34	1.24	1.10
dihomo-linoleoylcarnitine (C20:2)*	0.87	0.88	1.40
dihydrocaffeate sulfate (2)	1.11	1.37	1.80
dihydroferulic acid sulfate	0.92	1.00	0.78
dihydroorotate	1.17	1.13	0.54
dimethylarginine (SDMA + ADMA)	1.03	1.03	1.14
dimethylglycine	1.05	1.08	0.96
dimethylguanidino valeric acid (DMGV)*	1.28	0.97	0.30
dimethyl sulfone	1.34	2.42	1.06
docosadienoate (22:2n6)	1.19	1.19	1.21
docosadioate (C22-DC)	1.00	1.23	1.21
docosahexaenoate (DHA; 22:6n3)	1.21	1.17	1.24
docosahexaenoylcholine	1.45	1.40	1.70
docosapentaenoate (n3 DPA; 22:5n3)	1.19	1.19	0.95
docosapentaenoate (n6 DPA; 22:5n6)	1.29	1.27	1.02
docosapentaenoylcarnitine (C22:5n3)*	0.70	0.71	1.04
docosatrienoate (22:3n3)	1.20	1.19	0.75
docosatrienoate (22:3n6)*	1.50	1.25	0.78
dodecadienoate (12:2)*	1.03	1.07	1.17
dodecanedioate (C12-DC)	1.33	1.18	1.16
dodecenedioate (C12:1-DC)*	1.46	1.20	1.32
dopamine 3-O-sulfate	1.83	1.25	1.09
dopamine 4-sulfate	1.63	1.05	0.92
ectoine	1.23	1.85	2.00
EDTA	0.97	1.00	1.15
eicosanedioate (C20-DC)	0.97	1.08	1.38
eicosapentaenoate (EPA; 20:5n3)	1.32	1.29	1.14
eicosapentaenoylcholine	0.72	0.56	0.56
eicosenedioate (C20:1-DC)*	1.14	1.23	1.43
eicosenoate (20:1)	1.30	1.28	1.24
eicosenoylcarnitine (C20:1)*	0.96	1.04	1.67
enalapril	0.11	0.49	0.10
enalaprilat*	0.44	0.69	0.43
epiandrosterone sulfate	1.16	1.11	1.53
ergothioneine	1.03	1.18	1.39
erucate (22:1n9)	1.50	1.30	1.55
erythritol	1.10	1.27	0.97
erythronate*	1.11	1.11	0.84
escitalopram	0.94	0.92	0.92
ethyl alpha-glucopyranoside	2.56	2.18	2.12
ethyl glucuronide	3.25	0.91	0.37
ethylmalonate	1.11	1.13	1.49
etiocholanolone glucuronide	1.15	1.33	2.10
eugenol sulfate	3.53	2.51	2.02
febuxostat	0.01	0.05	0.01
ferulic acid 4-sulfate	1.07	1.03	0.21
fexofenadine	0.08	0.10	0.04
Fibrinopeptide A, des-ala(1)*	1.02	0.16	0.15
flavin adenine dinucleotide (FAD)	0.97	1.07	0.96
fluoxetine	1.00	1.00	1.00
formiminoglutamate	1.11	1.30	0.69
fructose	1.08	1.15	0.88
fructosyllysine	1.18	1.12	0.83
fumarate	1.22	1.14	0.73
furosemide	0.37	0.25	0.17
galactonate	1.33	0.94	0.53
gamma-CEHC	1.18	1.15	1.31
gamma-CEHC glucuronide*	0.96	0.86	0.53
gamma-glutamyl-2-aminobutyrate	0.97	0.97	0.94
gamma-glutamylalanine	1.16	1.00	0.42
gamma-glutamyl-alpha-lysine	1.00	1.02	1.07
gamma-glutamylcitrulline*	0.97	0.97	1.61
gamma-glutamyl-epsilon-lysine	1.02	1.05	1.04
gamma-glutamylglutamate	1.01	1.05	0.88
gamma-glutamylglutamine	1.05	1.02	1.14
gamma-glutamylglycine	1.08	1.08	1.25
gamma-glutamylhistidine	1.13	1.07	0.90
gamma-glutamylisoleucine*	1.09	1.06	0.85
gamma-glutamylleucine	1.07	1.03	0.86
gamma-glutamylmethionine	1.01	1.03	1.09
gamma-glutamylphenylalanine	1.03	1.03	0.95
gamma-glutamylthreonine	1.00	1.01	1.15
gamma-glutamyltryptophan	1.03	1.06	0.98
gamma-glutamyltyrosine	1.01	0.96	0.92
gamma-glutamylvaline	1.05	1.02	0.83
gamma-tocopherol/beta-tocopherol	1.03	1.02	1.34
gentisate	1.38	1.19	0.96
gluconate	1.09	1.06	0.76
glucose	1.09	1.03	0.81
glucuronate	1.16	1.14	0.89
glucuronide of C10H18O2 (7)*	6.75	2.92	0.76
glucuronide of C10H18O2 (8)*	1.98	1.00	0.41
glucuronide of piperine metabolite C17H21NO3 (3)*	0.63	0.86	0.66
glucuronide of piperine metabolite C17H21NO3 (4)*	1.16	1.61	0.99
glucuronide of piperine metabolite C17H21NO3 (5)*	0.68	0.76	0.72
glutamate	1.09	1.06	0.76
glutamine	1.00	0.99	1.13
glutamine conjugate of C6H10O2 (1)*	1.74	1.31	1.06
glutamine conjugate of C6H10O2 (2)*	2.06	1.34	1.05
glutamine conjugate of C7H12O2*	2.16	1.48	1.31
glutarate (C5-DC)	2.50	1.36	0.90
glutarylcarnitine (C5-DC)	1.00	1.04	1.28
glycerate	0.93	0.97	1.04
glycerol	1.18	1.26	0.69
glycerol 3-phosphate	1.19	1.02	0.53
glycerophosphoethanolamine	1.26	1.10	0.96
glycerophosphoinositol*	1.63	1.14	0.49
glycerophosphorylcholine (GPC)	1.12	1.59	2.34
glycerophosphoserine*	1.73	1.19	0.88
glycine	1.03	1.05	1.15
glycine conjugate of C10H12O2*	1.00	1.04	0.88
glycine conjugate of C10H14O2 (1)*	1.01	1.07	1.05
glyco-beta-muricholate**	0.94	1.20	0.52
glycochenodeoxycholate	1.32	1.33	0.59
glycochenodeoxycholate 3-sulfate	1.42	1.46	1.04
glycochenodeoxycholate glucuronide (1)	1.38	1.58	0.97
glycocholate	1.84	1.24	0.63
glycocholenate sulfate*	1.06	1.07	1.49
glycodeoxycholate	1.24	1.39	0.26
glycodeoxycholate 3-sulfate	1.15	1.54	0.49
glycolithocholate	1.12	1.10	0.22
glycolithocholate sulfate*	1.18	1.32	0.61
glycosyl ceramide (d16:1/24:1, d18:1/22:1)*	1.07	1.12	1.37
glycosyl ceramide (d18:1/20:0, d16:1/22:0)*	0.99	1.05	1.61
glycosyl ceramide (d18:1/23:1, d17:1/24:1)*	0.96	1.06	1.52
glycosyl ceramide (d18:2/24:1, d18:1/24:2)*	1.05	1.07	1.83
glycosyl-N-(2-hydroxynervonoyl)-sphingosine (d18:1/24:1(2OH)...	0.92	1.14	0.97
glycosyl-N-behenoyl-sphingadienine (d18:2/22:0)*	1.00	1.09	2.06
glycosyl-N-palmitoyl-sphingosine (d18:1/16:0)	1.02	0.98	1.38
glycosyl-N-stearoyl-sphingosine (d18:1/18:0)	0.99	1.04	1.36
glycosyl-N-tricosanoyl-sphingadienine (d18:2/23:0)*	0.91	1.12	2.08
glycoursodeoxycholate	2.55	1.95	0.78
glycoursodeoxycholic acid sulfate (1)	1.84	1.10	0.44
glycyrrhetinate	1.02	1.55	1.83
guaiacol sulfate	1.21	1.14	1.00
guanidinoacetate	0.97	1.03	1.45
guanidinosuccinate	0.80	1.18	1.00
guanine	0.99	0.66	12.73
gulonate*	1.22	1.12	0.76
heme	1.48	1.22	2.77
heneicosapentaenoate (21:5n3)	1.15	1.12	0.80
heptanoate (7:0)	1.21	1.18	1.14
heptenedioate (C7:1-DC)*	1.17	1.24	1.09
hexadecadienoate (16:2n6)	1.11	1.08	0.90
hexadecanedioate (C16-DC)	1.25	1.16	1.18
hexadecasphingosine (d16:1)*	1.00	1.07	1.13
hexadecenedioate (C16:1-DC)*	1.26	1.20	1.19
hexanoylcarnitine (C6)	1.08	1.08	1.10
hexanoylglutamine	1.45	1.23	0.99
hexanoylglycine	0.98	0.93	1.14
hippurate	1.28	1.16	2.06
histidine	1.00	1.01	1.12
histidine betaine (hercynine)*	0.90	1.01	1.47
homoarginine	0.99	1.08	1.19
homocitrulline	1.21	1.36	0.81
homostachydrine*	1.21	1.40	1.04
homovanillate (HVA)	0.86	0.99	1.09
hydantoin-5-propionate	1.13	1.20	0.63
hydrochlorothiazide	0.29	0.46	0.09
hydroquinone sulfate	1.24	1.38	0.97
hydroxyasparagine**	1.09	1.10	0.96
hydroxy-CMPF*	1.24	1.49	2.70
hydroxycotinine	0.32	0.30	0.10
hydroxy-N6,N6,N6-trimethyllysine*	1.02	1.08	0.99
hydroxypalmitoyl sphingomyelin (d18:1/16:0(OH))**	1.00	1.01	1.51
hyocholate	0.90	1.04	1.30
hypotaurine	1.19	1.12	1.22
hypoxanthine	1.11	1.14	0.95
ibuprofen	0.42	0.41	0.34
ibuprofen acyl glucuronide	0.13	0.15	0.12
imidazole lactate	1.06	1.10	1.19
imidazole propionate	2.60	2.42	1.27
iminodiacetate (IDA)	1.02	1.04	1.12
indole-3-carboxylate	1.04	1.04	1.01
indoleacetate	1.40	1.19	1.69
indoleacetoylcarnitine*	1.19	0.78	1.45
indoleacetylglutamine	1.43	1.06	1.14
indolebutyrate	1.22	1.00	1.01
indolelactate	0.96	1.05	1.02
indolepropionate	1.41	1.16	1.55
indolin-2-one	1.21	1.21	1.05
inosine	1.26	1.18	0.59
inosine 5^-monophosphate (IMP)	1.09	1.08	1.11
isobutyrylcarnitine (C4)	1.10	1.09	1.33
isobutyrylglycine	1.04	1.04	1.25
isocitrate	0.93	1.06	0.87
isocitric lactone	1.09	1.00	0.37
isoleucine	1.03	1.01	0.90
isoleucylglycine	0.89	0.96	1.40
isoursodeoxycholate	2.71	2.10	0.60
isoursodeoxycholate sulfate (1)	1.36	0.83	0.21
isovalerate (i5:0)	1.14	1.05	1.22
isovalerylcarnitine (C5)	1.02	1.08	1.24
kynurenate	0.99	1.06	0.97
kynurenine	1.03	1.07	1.03
lactate	1.15	1.14	0.75
lactosyl-N-behenoyl-sphingosine (d18:1/22:0)*	0.97	1.02	1.71
lactosyl-N-nervonoyl-sphingosine (d18:1/24:1)*	0.97	0.97	1.58
lactosyl-N-palmitoyl-sphingosine (d18:1/16:0)	1.00	0.98	1.49
lanthionine	0.95	0.84	0.50
laurate (12:0)	1.06	1.19	1.00
laurylcarnitine (C12)	1.05	1.08	1.63
leucine	1.01	1.00	0.93
leucylalanine	1.01	1.06	1.10
leucylglycine	0.93	0.95	1.28
lignoceroylcarnitine (C24)*	0.91	1.07	1.48
lignoceroyl sphingomyelin (d18:1/24:0)	0.99	1.01	1.43
linoleate (18:2n6)	1.17	1.08	1.00
linolenate [alpha or gamma; (18:3n3 or 6)]	1.21	1.14	0.91
linolenoylcarnitine (C18:3)*	0.75	0.72	1.18
linoleoyl-arachidonoyl-glycerol (18:2/20:4) [1]*	1.27	1.12	0.76
linoleoyl-arachidonoyl-glycerol (18:2/20:4) [2]*	1.29	1.12	0.78
linoleoylcarnitine (C18:2)*	0.99	1.01	1.57
linoleoylcholine*	1.59	1.41	2.07
linoleoyl-docosahexaenoyl-glycerol (18:2/22:6) [1]*	1.27	1.22	1.08
linoleoyl ethanolamide	1.06	0.94	1.14
linoleoyl-linolenoyl-glycerol (18:2/18:3) [1]*	1.30	1.15	1.29
linoleoyl-linolenoyl-glycerol (18:2/18:3) [2]*	1.02	0.75	0.63
linoleoyl-linoleoyl-glycerol (18:2/18:2) [1]*	1.24	1.08	1.32
linoleoyl-linoleoyl-glycerol (18:2/18:2) [2]*	1.28	1.17	1.28
lithocholate sulfate (1)	1.72	1.80	0.58
lithocholic acid sulfate (2)	0.98	1.31	0.70
L-urobilin	0.83	2.03	0.87
lysine	0.99	1.01	1.07
malate	1.22	1.18	0.89
maleate	1.29	1.94	0.46
malonate	1.04	1.09	1.02
malonylcarnitine	0.73	0.71	0.73
maltose	1.18	1.26	1.88
maltotriose	1.19	1.35	2.00
mannitol/sorbitol	2.14	1.85	1.77
mannonate*	1.10	1.04	0.68
mannose	1.08	1.01	0.74
margarate (17:0)	1.14	1.08	0.96
margaroylcarnitine (C17)*	0.92	1.05	1.46
metabolonic lactone sulfate	1.36	1.20	1.06
metformin	0.71	0.74	0.00
methionine	0.98	1.00	1.07
methionine sulfone	1.16	1.29	1.03
methionine sulfoxide	1.08	1.05	0.89
methyl-4-hydroxybenzoate sulfate	7.39	10.18	2.85
methyl glucopyranoside (alpha + beta)	1.23	1.57	2.32
methyl indole-3-acetate	1.38	1.20	1.24
methylmalonate (MMA)	1.49	1.13	0.97
methylsuccinate	1.08	1.03	0.93
metoprolol	0.56	0.24	0.15
metoprolol acid metabolite*	0.36	0.17	0.01
myo-inositol	1.13	1.08	1.10
myristate (14:0)	1.21	1.17	0.89
myristoleate (14:1n5)	1.16	1.17	0.97
myristoleoylcarnitine (C14:1)*	1.11	1.10	1.68
myristoylcarnitine (C14)	1.01	1.03	1.39
myristoyl dihydrosphingomyelin (d18:0/14:0)*	0.96	1.03	1.40
myristoyl-linoleoyl-glycerol (14:0/18:2) [1]*	1.29	1.23	0.67
myristoyl-linoleoyl-glycerol (14:0/18:2) [2]*	1.41	1.28	0.73
N1-Methyl-2-pyridone-5-carboxamide	1.28	1.39	1.05
N1-methyladenosine	1.05	1.04	0.99
N1-methylinosine	1.04	1.06	0.98
(N(1) + N(8))-acetylspermidine	1.14	0.98	1.11
N2-acetyl,N6-methyllysine	1.13	1.07	1.20
N2-acetyl,N6,N6-dimethyllysine	1.12	1.00	1.03
N-(2-furoyl)glycine	2.84	3.53	0.56
N2-methylguanosine	0.90	0.95	0.96
N2,N2-dimethylguanosine	1.13	1.07	1.04
N2,N5-diacetylornithine	1.24	1.30	1.49
N4-acetylcytidine	1.10	1.12	0.92
N6-acetyllysine	1.03	1.04	1.01
N6-carbamoylthreonyladenosine	1.09	1.08	1.08
N6-carboxymethyllysine	1.02	1.15	0.63
N6-methyllysine	1.87	1.82	1.54
N6,N6-dimethyllysine	1.41	1.35	1.46
N6,N6,N6-trimethyllysine	1.08	1.26	1.49
N6-succinyladenosine	0.92	0.95	0.75
N-acetyl-1-methylhistidine*	1.10	1.50	1.47
N-acetyl-2-aminooctanoate*	1.07	1.16	1.58
N-acetyl-3-methylhistidine*	0.68	1.51	0.84
N-acetylalanine	1.05	1.04	0.99
N-acetylalliin	1.04	1.19	1.97
N-acetylarginine	1.14	1.13	1.36
N-acetylaspartate (NAA)	0.99	0.98	0.91
N-acetyl-aspartyl-glutamate (NAAG)	0.86	1.07	0.93
N-acetyl-beta-alanine	1.11	0.94	1.02
N-acetylcarnosine	0.99	1.11	1.03
N-acetylcitrulline	1.15	1.30	1.02
N-acetylglucosamine/N-acetylgalactosamine	1.05	1.00	0.72
N-acetylglucosaminylasparagine	1.04	1.14	1.02
N-acetylglutamate	1.17	1.10	0.77
N-acetylglutamine	1.14	1.17	1.23
N-acetylglycine	1.23	1.08	1.52
N-acetylhistidine	1.12	1.00	1.15
N-acetyl-isoputreanine	1.14	1.06	1.01
N-acetylleucine	1.21	1.05	0.94
N-acetylmethionine	1.08	1.02	1.12
N-acetylneuraminate	1.04	1.07	1.07
N-acetylphenylalanine	1.15	1.11	1.01
N-acetylproline	1.03	0.92	0.88
N-acetylputrescine	1.15	1.04	0.95
N-acetylserine	1.13	1.08	1.05
N-acetyl sulfapyridine	1.00	1.00	1.00
N-acetyltaurine	1.32	1.21	0.91
N-acetylthreonine	1.10	1.09	1.08
N-acetyltryptophan	1.14	1.26	1.18
N-acetyltyrosine	1.09	1.06	1.08
N-acetylvaline	1.11	1.04	1.06
naproxen	1.00	1.00	1.00
N-behenoyl-sphingadienine (d18:2/22:0)*	1.00	1.09	1.68
N-carbamoylalanine	1.22	1.21	0.94
N-carbamoylaspartate	1.07	1.08	1.08
N-carbamoylvaline	0.99	0.96	0.95
N-delta-acetylornithine	1.22	1.39	1.31
N-desmethyl tramadol	0.13	0.29	0.13
nervonate (24:1n9)*	1.06	0.93	1.34
nervonoylcarnitine (C24:1)*	0.80	0.93	0.99
N-formylanthranilic acid	1.01	1.13	0.87
N-formylmethionine	1.05	1.02	0.99
N-formylphenylalanine	0.91	1.01	0.75
nicotinamide	1.01	1.00	1.27
nisinate (24:6n3)	1.33	1.23	0.74
N-methylhydroxyproline**	1.48	1.22	0.86
N-methylpipecolate	1.36	1.56	1.10
N-methylproline	3.35	2.86	1.97
N-methyltaurine	1.03	1.88	1.02
N,N-dimethyl-5-aminovalerate	1.43	1.13	0.41
N,N-dimethylalanine	1.07	1.27	1.87
N,N,N-trimethyl-5-aminovalerate	1.11	1.27	0.82
N,N,N-trimethyl-alanylproline betaine (TMAP)	0.99	1.09	1.22
N,O-didesmethylvenlafaxine glucuronide	1.00	1.00	1.00
N-oleoylserine	1.04	1.05	1.48
N-oleoyltaurine	1.15	1.00	1.32
nonadecanoate (19:0)	1.03	1.04	1.12
nonanoylcarnitine (C9)	1.08	0.96	1.35
norcotinine	0.52	0.54	0.48
norfluoxetine	1.00	1.00	1.00
N-oxalyl glycine (NOG)	1.05	1.17	1.08
N-palmitoylglycine	1.06	1.04	1.26
N-palmitoyl-heptadecasphingosine (d17:1/16:0)*	1.00	0.97	1.20
N-palmitoyl-sphingadienine (d18:2/16:0)*	1.04	1.01	1.34
N-palmitoyl-sphinganine (d18:0/16:0)	1.18	1.04	0.97
N-palmitoyl-sphingosine (d18:1/16:0)	1.04	0.96	1.11
N-stearoyl-sphingadienine (d18:2/18:0)*	1.07	1.05	1.16
N-stearoyl-sphinganine (d18:0/18:0)*	1.21	1.13	0.77
N-stearoyl-sphingosine (d18:1/18:0)*	1.05	1.02	1.06
N-stearoyltaurine	0.83	0.80	0.82
o-cresol sulfate	2.29	1.95	0.61
octadecadienedioate (C18:2-DC)*	1.82	1.07	1.31
octadecanedioate (C18-DC)	1.10	1.08	1.17
octadecanedioylcarnitine (C18-DC)*	1.08	1.09	1.44
octadecenedioate (C18:1-DC)*	1.21	1.12	1.08
octadecenedioylcarnitine (C18:1-DC)*	1.20	1.13	1.56
octanoylcarnitine (C8)	1.11	1.03	1.39
O-desmethyltramadol	0.13	0.21	0.13
O-desmethyltramadol glucuronide	0.12	0.20	0.12
O-desmethylvenlafaxine	1.00	1.00	1.00
oleate/vaccenate (18:1)	1.16	1.11	0.99
oleoyl-arachidonoyl-glycerol (18:1/20:4) [1]*	1.20	1.11	0.78
oleoyl-arachidonoyl-glycerol (18:1/20:4) [2]*	1.29	1.16	0.75
oleoylcarnitine (C18:1)	1.03	1.08	1.52
oleoylcholine	1.37	1.32	1.59
oleoyl ethanolamide	1.16	1.07	1.24
oleoyl-linolenoyl-glycerol (18:1/18:3) [2]*	1.16	1.02	1.11
oleoyl-linoleoyl-glycerol (18:1/18:2) [1]	1.20	1.07	1.13
oleoyl-linoleoyl-glycerol (18:1/18:2) [2]	1.25	1.06	1.09
oleoyl-oleoyl-glycerol (18:1/18:1) [1]*	1.21	1.06	0.97
oleoyl-oleoyl-glycerol (18:1/18:1) [2]*	1.27	1.09	0.98
omeprazole	0.42	0.82	0.30
ornithine	0.98	1.00	1.12
orotate	1.38	1.26	1.08
orotidine	2.26	1.67	0.91
O-sulfo-L-tyrosine	1.06	1.13	1.12
oxalate (ethanedioate)	0.93	0.96	1.05
oxypurinol	0.91	0.91	0.91
palmitate (16:0)	1.15	1.11	0.96
palmitoleate (16:1n7)	1.44	1.26	0.90
palmitoleoyl-arachidonoyl-glycerol (16:1/20:4) [2]*	1.19	1.08	0.69
palmitoleoylcarnitine (C16:1)*	1.06	1.04	1.40
palmitoleoyl-linoleoyl-glycerol (16:1/18:2) [1]*	1.33	1.14	0.95
palmitoleoyl-oleoyl-glycerol (16:1/18:1) [1]*	1.52	1.32	1.01
palmitoleoyl-oleoyl-glycerol (16:1/18:1) [2]*	1.35	1.26	0.88
palmitoyl-arachidonoyl-glycerol (16:0/20:4) [1]*	1.33	1.14	0.77
palmitoyl-arachidonoyl-glycerol (16:0/20:4) [2]*	1.45	1.23	0.49
palmitoylcarnitine (C16)	1.03	1.10	1.38
palmitoylcholine	1.55	1.39	1.65
palmitoyl dihydrosphingomyelin (d18:0/16:0)*	0.99	1.02	1.41
palmitoyl-docosahexaenoyl-glycerol (16:0/22:6) [1]*	1.47	1.20	0.81
palmitoyl-linoleoyl-glycerol (16:0/18:2) [1]*	1.43	1.39	1.13
palmitoyl-linoleoyl-glycerol (16:0/18:2) [2]*	1.40	1.17	0.93
palmitoyl-oleoyl-glycerol (16:0/18:1) [1]*	1.49	1.24	0.87
palmitoyl-oleoyl-glycerol (16:0/18:1) [2]*	1.53	1.25	0.91
palmitoyl sphingomyelin (d18:1/16:0)	0.98	0.99	1.24
palmitoyl-sphingosine-phosphoethanolamine (d18:1/16:0)	1.00	1.00	1.27
pantoate	1.34	1.65	0.81
pantoprazole	0.12	0.57	0.10
pantothenate	1.27	1.34	0.84
paraxanthine	1.06	1.19	0.86
p-cresol glucuronide*	1.67	1.51	1.26
p-cresol sulfate	1.09	1.17	1.13
pentadecanoate (15:0)	1.16	1.11	0.98
pentose acid*	1.87	1.44	1.60
perfluorooctanesulfonate (PFOS)	1.04	1.19	1.42
perfluorooctanoate (PFOA)	0.93	1.25	1.85
phenol sulfate	1.49	1.95	1.08
phenylacetate	0.97	1.07	0.88
phenylacetylcarnitine	0.91	0.77	0.83
phenylacetylglutamate	0.88	1.11	0.89
phenylacetylglutamine	1.05	1.07	0.94
phenylacetylglycine	0.85	0.70	0.28
phenylalanine	1.00	1.02	1.00
phenyllactate (PLA)	1.18	1.20	1.15
phenylpyruvate	0.99	1.06	0.96
phosphate	1.02	0.98	1.00
phosphoethanolamine	0.97	1.03	1.05
picolinate	1.09	1.13	0.87
picolinoylglycine	1.04	1.09	0.74
pimeloylcarnitine/3-methyladipoylcarnitine (C7-DC)	0.84	0.91	1.49
pipecolate	1.26	0.99	1.19
piperine	1.24	1.86	1.15
pregabalin	0.29	0.29	0.27
pregnanediol-3-glucuronide	1.00	1.13	1.48
pregnenediol disulfate (C21H34O8S2)*	1.14	1.52	1.39
pregnenediol sulfate (C21H34O5S)*	0.96	1.18	1.45
pregnenetriol disulfate*	1.15	1.35	1.26
pregnenetriol sulfate*	0.90	1.07	1.25
pregnenolone sulfate	0.92	1.08	1.22
pro-hydroxy-pro	1.22	1.10	1.23
proline	1.05	1.03	0.83
prolylglycine	1.18	1.04	1.05
propionylcarnitine (C3)	1.05	1.10	0.99
propionylglycine	1.10	1.09	0.89
propyl 4-hydroxybenzoate sulfate	0.40	0.60	0.25
pseudouridine	1.09	1.08	1.05
pyridoxate	1.80	1.45	1.13
pyroglutamine*	1.22	1.09	1.31
pyrraline	1.06	1.12	0.83
pyruvate	1.10	1.11	0.79
quinate	1.26	1.24	1.11
quinine	0.40	1.86	0.27
quinolinate	1.15	1.15	1.27
(R)-3-hydroxybutyrylcarnitine	1.70	1.22	0.97
retinal	0.95	0.91	0.94
retinol (Vitamin A)	0.96	1.07	1.00
ribitol	1.12	1.02	0.85
ribonate	1.07	1.04	0.81
ribulonate/xylulonate/lyxonate*	1.21	1.26	1.17
S-1-pyrroline-5-carboxylate	1.04	1.12	1.28
(S)-3-hydroxybutyrylcarnitine	1.36	1.21	1.06
saccharin	1.70	3.11	0.21
S-adenosylhomocysteine (SAH)	1.02	1.04	1.12
salicylate	53.19	37.48	0.90
salicyluric glucuronide*	0.55	0.48	0.01
sarcosine	1.01	1.00	1.10
sebacate (C10-DC)	1.42	1.29	1.11
sedoheptulose	1.25	1.10	1.07
serine	0.99	1.03	1.12
serotonin	0.99	1.09	1.12
sitagliptin	0.18	0.21	0.03
S-methylcysteine	1.14	1.07	1.03
S-methylcysteine sulfoxide	1.23	1.16	0.94
spermidine	1.02	1.03	1.14
sphingadienine	1.07	1.12	1.41
sphinganine	1.15	1.16	1.37
sphinganine-1-phosphate	1.07	1.09	1.07
sphingomyelin (d17:1/14:0, d16:1/15:0)*	0.99	1.08	1.64
sphingomyelin (d17:1/16:0, d18:1/15:0, d16:1/17:0)*	0.99	1.05	1.42
sphingomyelin (d17:2/16:0, d18:2/15:0)*	0.94	1.10	1.49
sphingomyelin (d18:0/18:0, d19:0/17:0)*	1.00	1.13	0.80
sphingomyelin (d18:0/20:0, d16:0/22:0)*	1.00	1.14	0.94
sphingomyelin (d18:1/14:0, d16:1/16:0)*	0.97	1.01	1.24
sphingomyelin (d18:1/17:0, d17:1/18:0, d19:1/16:0)	0.98	1.08	1.30
sphingomyelin (d18:1/18:1, d18:2/18:0)	1.00	1.09	1.14
sphingomyelin (d18:1/19:0, d19:1/18:0)*	1.00	1.13	1.25
sphingomyelin (d18:1/20:0, d16:1/22:0)*	0.98	1.05	1.19
sphingomyelin (d18:1/20:1, d18:2/20:0)*	0.97	1.07	1.15
sphingomyelin (d18:1/20:2, d18:2/20:1, d16:1/22:2)*	0.98	1.13	1.11
sphingomyelin (d18:1/21:0, d17:1/22:0, d16:1/23:0)*	0.97	1.08	1.34
sphingomyelin (d18:1/22:1, d18:2/22:0, d16:1/24:1)*	0.95	1.03	1.31
sphingomyelin (d18:1/22:2, d18:2/22:1, d16:1/24:2)*	0.96	1.04	1.15
sphingomyelin (d18:1/24:1, d18:2/24:0)*	0.98	1.02	1.27
sphingomyelin (d18:1/25:0, d19:0/24:1, d20:1/23:0, d19:1/24:...	0.96	0.99	1.18
sphingomyelin (d18:2/14:0, d18:1/14:1)*	0.96	1.08	1.44
sphingomyelin (d18:2/16:0, d18:1/16:1)*	0.94	1.01	1.31
sphingomyelin (d18:2/18:1)*	0.99	1.07	1.36
sphingomyelin (d18:2/21:0, d16:2/23:0)*	0.96	1.13	1.42
sphingomyelin (d18:2/23:0, d18:1/23:1, d17:1/24:1)*	0.96	1.07	1.50
sphingomyelin (d18:2/23:1)*	0.97	1.10	1.54
sphingomyelin (d18:2/24:1, d18:1/24:2)*	0.97	1.05	1.40
sphingomyelin (d18:2/24:2)*	1.01	1.07	1.43
sphingosine	1.16	1.14	1.21
sphingosine 1-phosphate	1.04	1.06	1.11
stachydrine	1.76	1.64	1.21
stearate (18:0)	1.05	1.02	1.00
stearidonate (18:4n3)	1.12	1.15	0.82
stearoyl-arachidonoyl-glycerol (18:0/20:4) [1]*	1.17	1.11	0.91
stearoyl-arachidonoyl-glycerol (18:0/20:4) [2]*	1.03	0.94	1.00
stearoylcarnitine (C18)	0.97	1.07	1.62
stearoylcholine*	1.38	1.33	1.48
stearoyl sphingomyelin (d18:1/18:0)	0.99	1.05	0.96
suberate (C8-DC)	1.10	0.94	0.76
succinate	1.08	1.04	1.01
succinimide	1.04	1.07	2.02
succinoyltaurine	1.20	1.25	0.94
succinylcarnitine (C4-DC)	1.03	1.09	0.88
sucrose	2.07	1.46	0.83
sulfate*	1.00	1.07	1.02
sulfate of piperine metabolite C16H19NO3 (2)*	1.01	1.59	1.07
sulfate of piperine metabolite C16H19NO3 (3)*	0.91	1.51	1.01
sulfate of piperine metabolite C18H21NO3 (1)*	0.80	1.40	1.10
sulfate of piperine metabolite C18H21NO3 (3)*	0.77	1.32	1.00
tartarate	5.66	0.83	1.19
tartronate (hydroxymalonate)	1.08	1.15	1.26
taurine	0.97	1.02	1.14
taurochenodeoxycholate	1.79	1.57	0.60
taurochenodeoxycholic acid 3-sulfate	1.13	1.15	1.14
taurocholate	1.92	1.03	0.27
taurocholenate sulfate*	1.23	1.19	1.93
taurodeoxycholate	1.44	1.66	0.18
taurodeoxycholic acid 3-sulfate	1.02	1.49	0.53
taurolithocholate 3-sulfate	1.12	1.39	0.80
tetradecadienedioate (C14:2-DC)*	1.33	1.23	1.36
tetradecadienoate (14:2)*	1.09	1.13	1.20
tetradecanedioate (C14-DC)	1.44	1.24	1.43
tetrahydrocortisol sulfate (1)	0.87	0.92	0.55
theobromine	1.27	1.19	1.67
theophylline	0.98	1.06	0.93
thioproline	1.04	1.08	0.93
threonate	1.03	1.03	0.94
threonine	0.98	1.03	1.19
thymol sulfate	1.29	3.28	3.00
thyroxine	1.03	1.04	1.02
tiglylcarnitine (C5:1-DC)	1.00	1.03	0.93
tramadol	0.05	0.12	0.05
trans-4-hydroxyproline	1.17	1.17	0.96
trans-urocanate	1.08	1.02	1.27
tricosanoyl sphingomyelin (d18:1/23:0)*	0.98	1.03	1.40
tridecenedioate (C13:1-DC)*	1.10	1.11	1.18
trigonelline (N^-methylnicotinate)	1.09	1.16	0.86
trimethylamine N-oxide	1.11	1.21	1.15
tryptophan	1.00	1.06	1.07
tryptophan betaine	1.51	2.93	5.43
tyramine O-sulfate	2.25	2.93	0.74
tyrosine	1.00	1.04	1.03
umbelliferone sulfate	1.58	2.12	0.29
undecanedioate (C11-DC)	0.95	0.98	0.99
undecenoylcarnitine (C11:1)	1.03	1.10	1.37
uracil	1.03	1.03	1.21
urate	0.96	1.06	1.05
urea	0.99	1.17	1.09
uridine	1.01	1.00	1.18
ursodeoxycholate	1.40	1.20	0.47
valine	1.01	1.00	0.93
valylglycine	0.83	0.83	1.16
vanillactate	1.08	1.12	1.03
vanillic acid glycine	1.29	1.31	1.06
vanillylmandelate (VMA)	0.92	1.03	1.30
venlafaxine	1.00	1.00	1.00
verapamil	1.00	1.00	1.00
warfarin	0.09	0.12	0.00
xanthine	1.15	1.33	1.09
xanthurenate	1.04	1.26	0.84
ximenoylcarnitine (C26:1)*	0.94	1.16	1.64
xylose	1.20	1.16	0.86
zolpidem	0.32	0.34	0.32

Factors:

F1	Group:Diabetic Neuropathy
F2	Group:Diabetic non neuropathy
F3	Group:Normal