Metabolomics Workbench : NIH Data Repository : Analyze Studies

Data for ST001869

(Analysis AN003031): Average values per metabolite and experimental factor (Units:relative value)

Metabolite structure	F1	F2	F3
10-heptadecenoate (17:1n7)	1.17	0.94	1.23
10-nonadecenoate (19:1n9)	1.24	0.91	1.21
1-(1-enyl-oleoyl)-GPE (P-18:1)*	1.25	0.97	1.07
1-(1-enyl-palmitoyl)-2-arachidonoyl-GPC (P-16:0/20:4)*	0.91	0.87	1.11
1-(1-enyl-palmitoyl)-2-arachidonoyl-GPE (P-16:0/20:4)*	1.03	0.98	0.90
1-(1-enyl-palmitoyl)-2-linoleoyl-GPC (P-16:0/18:2)*	1.97	0.95	0.91
1-(1-enyl-palmitoyl)-2-linoleoyl-GPE (P-16:0/18:2)*	1.31	0.86	0.97
1-(1-enyl-palmitoyl)-2-oleoyl-GPE (P-16:0/18:1)*	0.99	1.12	1.00
1-(1-enyl-palmitoyl)-2-palmitoyl-GPC (P-16:0/16:0)*	1.09	0.89	0.98
1-(1-enyl-palmitoyl)-GPC (P-16:0)*	1.03	1.00	1.05
1-(1-enyl-palmitoyl)-GPE (P-16:0)*	1.20	1.04	1.02
1-(1-enyl-stearoyl)-2-arachidonoyl-GPE (P-18:0/20:4)*	0.96	0.94	1.04
1-(1-enyl-stearoyl)-2-linoleoyl-GPE (P-18:0/18:2)*	1.17	0.91	0.99
1-(1-enyl-stearoyl)-2-oleoyl-GPE (P-18:0/18:1)	0.78	1.22	0.95
1-(1-enyl-stearoyl)-GPE (P-18:0)*	0.99	0.94	1.03
1,2-dilinoleoyl-GPC (18:2/18:2)	2.72	0.90	0.93
1,2-dilinoleoyl-GPE (18:2/18:2)*	4.32	1.03	1.19
1,2-dipalmitoyl-GPC (16:0/16:0)	0.95	1.10	0.96
1,2-dipalmitoyl-GPE (16:0/16:0)*	1.03	0.96	0.99
1,2-dipalmitoyl-GPG (16:0/16:0)	0.89	0.95	1.04
1,2-distearoyl-GPC (18:0/18:0)	1.03	0.90	1.08
12-HETE	0.97	1.20	1.27
12-HHTrE	0.50	1.18	0.46
13-HODE + 9-HODE	1.36	0.87	1.26
1,5-anhydroglucitol (1,5-AG)	0.92	1.04	1.02
(16 or 17)-methylstearate (a19:0 or i19:0)	0.93	1.07	1.28
18-methylnonadecanoate (i20:0)	1.02	0.94	1.31
1-arachidonoyl-GPA (20:4)	0.87	1.01	1.30
1-arachidonoyl-GPC* (20:4)*	1.00	1.03	1.25
1-arachidonoyl-GPE (20:4n6)*	1.01	0.98	1.26
1-arachidonoyl-GPI* (20:4)*	0.93	1.30	1.15
1-arachidonylglycerol (20:4)	0.91	1.17	1.40
1-carboxyethylisoleucine	1.06	1.36	0.90
1-carboxyethylleucine	1.12	1.51	1.03
1-carboxyethylphenylalanine	1.14	1.71	1.06
1-carboxyethyltyrosine	1.21	1.91	1.08
1-carboxyethylvaline	1.11	1.65	0.99
1-dihomo-linolenylglycerol (20:3)	1.04	1.04	1.25
1-dihomo-linoleoylglycerol (20:2)	1.20	0.93	1.44
1-docosahexaenoylglycerol (22:6)	0.90	1.08	2.63
1-heptadecenoylglycerol (17:1)*	0.90	0.58	0.89
1-lignoceroyl-GPC (24:0)	1.01	1.07	1.00
1-linolenoylglycerol (18:3)	1.65	0.78	1.19
1-linolenoyl-GPC (18:3)*	2.12	0.77	0.99
1-linolenoyl-GPG (18:3)*	0.69	1.07	0.76
1-linoleoyl-2-arachidonoyl-GPC (18:2/20:4n6)*	1.29	0.68	0.97
1-linoleoyl-2-arachidonoyl-GPE (18:2/20:4)*	2.15	0.67	1.01
1-linoleoyl-2-linolenoyl-GPC (18:2/18:3)*	3.75	1.08	0.92
1-linoleoylglycerol (18:2)	1.31	0.74	1.19
1-linoleoyl-GPC (18:2)	2.19	0.89	0.98
1-linoleoyl-GPE (18:2)*	1.79	0.74	1.14
1-linoleoyl-GPG (18:2)*	0.87	1.13	1.21
1-linoleoyl-GPI* (18:2)*	1.43	1.15	1.22
1-linoleoyl-GPS (18:2)*	0.85	0.98	1.21
1-meadoylglycerol (20:3n9)*	0.77	1.27	1.65
1-methyl-4-imidazoleacetate	1.07	1.16	1.61
1-methyl-5-imidazoleacetate	1.02	1.18	1.04
1-methyladenosine	0.99	1.11	0.96
1-methylguanidine	1.12	0.78	1.10
1-methylhistidine	0.83	1.75	1.06
1-methylnicotinamide	1.22	1.04	0.84
1-myristoyl-2-arachidonoyl-GPC (14:0/20:4)*	0.70	1.21	0.99
1-myristoyl-2-palmitoyl-GPC (14:0/16:0)	0.93	1.30	0.90
1-oleoyl-2-arachidonoyl-GPE (18:1/20:4)*	1.18	0.97	0.85
1-oleoyl-2-arachidonoyl-GPI (18:1/20:4)*	1.18	0.82	1.04
1-oleoyl-2-docosahexaenoyl-GPC (18:1/22:6)*	0.77	1.07	1.28
1-oleoyl-2-docosahexaenoyl-GPE (18:1/22:6)*	0.90	0.97	1.18
1-oleoyl-2-linoleoyl-GPC (18:1/18:2)*	1.38	0.92	0.91
1-oleoyl-2-linoleoyl-GPE (18:1/18:2)*	2.26	1.00	1.00
1-oleoylglycerol (18:1)	1.15	0.83	1.32
1-oleoyl-GPC (18:1)	1.19	0.96	1.00
1-oleoyl-GPE (18:1)	1.64	0.92	1.07
1-oleoyl-GPG (18:1)*	0.82	1.11	1.41
1-oleoyl-GPI (18:1)	0.98	1.28	1.11
1-oleoyl-GPS (18:1)	0.58	1.21	1.20
1-palmitoleoyl-2-linolenoyl-GPC (16:1/18:3)*	3.31	0.97	0.92
1-palmitoleoyl-2-linoleoyl-GPC (16:1/18:2)*	0.69	1.22	0.97
1-palmitoleoylglycerol (16:1)*	1.50	0.78	1.40
1-palmitoleoyl-GPC* (16:1)*	1.45	1.04	1.07
1-palmitoyl-2-arachidonoyl-GPC (16:0/20:4n6)	0.87	1.04	1.06
1-palmitoyl-2-arachidonoyl-GPE (16:0/20:4)*	1.13	1.10	0.89
1-palmitoyl-2-arachidonoyl-GPI (16:0/20:4)*	1.12	0.98	0.94
1-palmitoyl-2-docosahexaenoyl-GPC (16:0/22:6)	0.67	1.17	1.29
1-palmitoyl-2-docosahexaenoyl-GPE (16:0/22:6)*	0.65	1.08	1.16
1-palmitoyl-2-linoleoyl-GPC (16:0/18:2)	1.31	0.96	0.89
1-palmitoyl-2-linoleoyl-GPE (16:0/18:2)	1.73	0.97	0.86
1-palmitoyl-2-linoleoyl-GPG (16:0/18:2)	1.49	0.74	0.98
1-palmitoyl-2-linoleoyl-GPI (16:0/18:2)	1.39	0.89	1.01
1-palmitoyl-2-oleoyl-GPC (16:0/18:1)	0.92	1.10	0.99
1-palmitoyl-2-oleoyl-GPE (16:0/18:1)	1.01	1.06	0.98
1-palmitoyl-2-oleoyl-GPG (16:0/18:1)	0.92	1.06	1.08
1-palmitoyl-2-oleoyl-GPI (16:0/18:1)*	0.89	0.91	1.07
1-palmitoyl-2-palmitoleoyl-GPC (16:0/16:1)*	0.95	1.30	0.91
1-palmitoyl-2-stearoyl-GPC (16:0/18:0)	0.96	1.07	1.05
1-palmitoyl-2-stearoyl-GPE (16:0/18:0)*	0.99	0.91	1.13
1-palmitoyl-GPA (16:0)	1.07	0.98	1.67
1-palmitoyl-GPC (16:0)	1.09	0.98	0.93
1-palmitoyl-GPE (16:0)	1.15	1.06	1.00
1-palmitoyl-GPG (16:0)*	1.05	0.95	1.40
1-palmitoyl-GPI* (16:0)	0.79	1.39	1.09
1-ribosyl-imidazoleacetate*	1.21	1.04	1.16
1-stearoyl-2-arachidonoyl-glycosyl-GPE (18:0/20:4)	1.47	0.81	1.11
1-stearoyl-2-arachidonoyl-GPC (18:0/20:4)	0.94	0.98	1.09
1-stearoyl-2-arachidonoyl-GPE (18:0/20:4)	1.09	1.06	0.89
1-stearoyl-2-arachidonoyl-GPI (18:0/20:4)	0.89	0.97	0.99
1-stearoyl-2-arachidonoyl-GPS (18:0/20:4)	0.92	1.20	0.88
1-stearoyl-2-docosahexaenoyl-GPC (18:0/22:6)	0.66	1.21	1.37
1-stearoyl-2-docosahexaenoyl-GPE (18:0/22:6)*	0.71	1.00	1.27
1-stearoyl-2-linoleoyl-GPC (18:0/18:2)*	1.57	0.99	0.97
1-stearoyl-2-linoleoyl-GPE (18:0/18:2)*	1.48	1.03	0.91
1-stearoyl-2-linoleoyl-GPI (18:0/18:2)	1.17	0.94	1.04
1-stearoyl-2-linoleoyl-GPS (18:0/18:2)	1.20	1.11	0.85
1-stearoyl-2-oleoyl-GPC (18:0/18:1)	0.91	1.13	1.03
1-stearoyl-2-oleoyl-GPE (18:0/18:1)	0.73	1.23	1.00
1-stearoyl-2-oleoyl-GPS (18:0/18:1)	0.88	1.44	0.94
1-stearoyl-GPC (18:0)	1.11	0.97	0.95
1-stearoyl-GPE (18:0)	1.22	1.03	1.00
1-stearoyl-GPG (18:0)	0.87	1.13	1.40
1-stearoyl-GPI (18:0)	0.80	1.59	1.19
1-stearoyl-GPS (18:0)*	0.98	1.34	0.99
2,3-dihydroxy-5-methylthio-4-pentenoate (DMTPA)*	0.94	1.06	1.02
2,3-dihydroxyisovalerate	0.92	1.21	2.20
2,4-dihydroxybutyrate	0.77	1.08	1.21
2,4-di-tert-butylphenol	1.27	1.09	1.18
2,6-dihydroxybenzoic acid	1.47	0.80	0.97
2,8-quinolinediol sulfate	2.80	0.75	0.37
2-aminoadipate	0.85	1.16	0.97
2-aminoheptanoate	1.18	0.80	0.91
2-aminophenol sulfate	1.78	0.93	0.81
2-arachidonoylglycerol (20:4)	0.95	1.13	1.34
2^-deoxyadenosine	1.18	1.29	1.11
2^-deoxyadenosine 5^-monophosphate	0.49	1.67	1.00
2^-deoxycytidine	0.88	1.06	1.03
2^-deoxyguanosine	0.95	0.97	0.93
2^-deoxyinosine	0.79	1.47	1.12
2^-deoxyuridine	0.83	1.29	1.02
2-docosahexaenoylglycerol (22:6)*	0.95	1.09	2.45
2-hydroxy-3-methylvalerate	1.18	1.30	0.75
2-hydroxybutyrate/2-hydroxyisobutyrate	0.81	1.32	1.15
2-hydroxydecanoate	1.09	0.83	1.02
2-hydroxyglutarate	1.08	0.99	1.06
2-hydroxyheptanoate*	1.12	0.99	1.01
2-hydroxyoctanoate	0.81	0.77	0.89
2-linoleoylglycerol (18:2)	1.35	0.73	1.17
2-methylbutyrylcarnitine (C5)	0.97	1.11	1.21
2-methylcitrate/homocitrate	0.52	1.57	1.00
2-methylmalonylcarnitine (C4-DC)	1.04	0.90	1.11
2-myristoylglycerol (14:0)	1.38	0.81	1.48
2-naphthol sulfate	0.38	1.19	1.10
2-oleoylglycerol (18:1)	1.16	0.76	1.28
2-O-methylascorbic acid	1.13	1.01	0.80
2^-O-methyluridine	0.83	1.70	1.12
2-oxoarginine*	0.77	0.76	1.51
2-palmitoleoylglycerol (16:1)*	1.73	0.81	1.46
2-palmitoylglycerol (16:0)	1.19	0.78	1.32
2-palmitoyl-GPC* (16:0)*	1.08	1.11	1.00
2R,3R-dihydroxybutyrate	0.59	1.05	1.16
2S,3R-dihydroxybutyrate	0.61	1.12	1.08
2-stearoyl-GPE (18:0)*	1.23	1.13	1.14
3-(3-hydroxyphenyl)propionate sulfate	0.42	0.45	1.82
3,4-dihydroxybutyrate	0.81	1.17	1.15
3-(4-hydroxyphenyl)lactate (HPLA)	1.20	1.19	1.03
3-amino-2-piperidone	0.71	1.47	0.89
3^-AMP	1.33	0.82	1.02
3^-dephospho-acetyl-CoA	1.01	0.65	1.05
3^-dephospho-CoA-glutathione*	0.74	0.96	0.96
3^-dephosphocoenzyme A	0.89	1.85	1.27
3-formylindole	1.08	0.91	1.04
3-hydroxy-2-ethylpropionate	0.86	1.14	1.05
3-hydroxy-3-methylglutarate	0.79	1.39	1.00
3-hydroxyadipate	0.52	1.32	1.20
3-hydroxybutyrate (BHBA)	0.58	1.33	1.48
3-hydroxydecanoylcarnitine	1.71	1.12	1.55
3-hydroxyhexanoate	0.99	1.21	1.46
3-hydroxyhexanoylcarnitine (1)	0.90	1.03	1.56
3-hydroxyhexanoylcarnitine (2)	0.74	1.01	1.35
3-hydroxyisobutyrate	0.57	1.54	1.20
3-hydroxylaurate	0.77	1.06	1.38
3-hydroxymyristate	0.83	0.96	1.19
3-hydroxyoctanoate	0.90	1.13	1.20
3-hydroxyoctanoylcarnitine (1)	1.31	1.13	1.71
3-hydroxyoctanoylcarnitine (2)	1.09	1.05	1.64
3-hydroxyoleate*	1.07	0.97	1.04
3-hydroxyoleoylcarnitine	1.68	1.34	1.85
3-hydroxypalmitoylcarnitine	1.89	1.43	1.93
3-indoxyl sulfate	0.86	0.97	1.29
3-methoxytyrosine	0.83	1.04	1.46
3-methylglutaconate	1.06	1.38	0.91
3-methylhistidine	1.05	0.97	1.00
3-phenylpropionate (hydrocinnamate)	1.60	0.54	1.16
3-phosphoglycerate	1.38	0.92	0.93
3-ureidopropionate	2.15	2.84	0.86
4-acetylphenyl sulfate	1.09	0.85	0.62
4-chlorobenzoic acid	1.01	1.03	1.02
4-cholesten-3-one	0.91	0.87	1.11
4-ethylphenol glucuronide	1.42	0.98	0.74
4-ethylphenyl sulfate	1.96	0.86	0.53
4-guanidinobutanoate	2.17	0.78	0.89
4-hydroxybutyrate (GHB)	1.34	1.31	1.20
4-hydroxyglutamate	1.11	1.32	1.01
4-hydroxy-nonenal-glutathione	0.97	1.00	1.00
4-imidazoleacetate	1.63	0.94	0.98
4-methylcatechol sulfate	1.54	0.98	1.15
4-vinylphenol sulfate	1.10	0.73	0.97
5,6-dihydrouridine	0.90	1.06	0.97
5-aminovalerate	0.87	1.03	1.39
5-dodecenoate (12:1n7)	0.99	1.00	1.40
5-dodecenoylcarnitine (C12:1)	1.30	0.89	1.65
5-(galactosylhydroxy)-L-lysine	0.70	1.90	1.02
5^- GMP	0.91	1.10	1.06
5-hydroxyindoleacetate	1.27	0.93	1.01
5-hydroxylysine	0.99	0.94	0.98
5-methyl-2^-deoxycytidine	1.03	1.13	0.79
5-methylcytidine	0.95	1.06	0.96
5-methylthioadenosine (MTA)	0.88	1.13	1.06
5-methyluridine (ribothymidine)	0.93	2.30	0.94
5-oxoproline	1.03	0.88	1.11
6-phosphogluconate	1.00	1.14	0.89
7-HOCA	0.62	1.19	2.19
7-ketodeoxycholate	0.34	5.03	3.92
7-methylguanine	0.60	1.03	0.73
acetylcarnitine (C2)	1.21	0.72	1.09
acetylcholine	0.82	1.04	1.13
acetyl-CoA	1.26	0.74	1.13
acetylphosphate	1.02	0.87	0.90
acisoga	0.80	1.66	1.08
aconitate [cis or trans]	0.98	1.12	1.06
adenine	1.25	0.95	1.06
adenosine	1.34	0.85	1.03
adenosine 3^,5^-cyclic monophosphate (cAMP)	1.08	0.92	1.04
adenosine 3^,5^-diphosphate	1.37	0.74	1.13
adenosine 5^-diphosphoribose (ADP-ribose)	1.03	0.95	1.18
adenylosuccinate	0.98	1.14	0.87
ADP	1.12	0.93	0.97
adrenate (22:4n6)	0.86	1.08	1.86
adrenoylcarnitine (C22:4)*	2.14	0.92	1.93
AICA ribonucleotide	0.67	1.25	1.25
alanine	0.90	1.21	1.05
alanylleucine	1.03	0.94	0.74
allantoin	0.89	1.10	1.03
alpha-hydroxyisocaproate	1.42	1.19	0.77
alpha-hydroxyisovalerate	0.84	1.30	1.09
alpha-ketoglutaramate*	1.13	0.74	1.13
alpha-ketoglutarate	0.99	0.90	1.05
alpha-muricholate	0.77	1.62	3.03
alpha-tocopherol	1.11	0.96	0.91
alpha-tocotrienol	1.12	0.79	1.03
AMP	0.91	0.94	1.09
anserine	1.50	0.69	1.00
arabitol/xylitol	1.17	1.08	0.87
arabonate/xylonate	1.16	1.05	0.92
arachidate (20:0)	1.07	0.98	1.09
arachidonate (20:4n6)	0.88	1.03	1.52
arachidonoylcarnitine (C20:4)	1.11	0.79	1.24
arachidonoyl CoA	0.58	1.06	0.97
arachidonoyl ethanolamide	1.48	1.00	0.97
arachidoylcarnitine (C20)*	1.08	1.15	1.79
arginine	1.13	0.83	1.17
argininosuccinate	0.87	1.40	1.32
ascorbate (Vitamin C)	0.40	2.75	0.66
ascorbic acid 3-sulfate*	1.21	1.37	0.86
asparagine	1.17	0.96	0.96
aspartate	0.63	1.49	1.06
azelate (C9-DC)	0.95	1.17	1.01
behenate (22:0)*	0.94	1.06	1.28
behenoylcarnitine (C22)*	1.11	0.91	1.52
behenoyl sphingomyelin (d18:1/22:0)*	0.99	0.95	1.19
benzoate	1.12	1.04	1.15
beta-alanine	1.00	1.10	0.97
beta-citrylglutamate	0.51	2.23	0.98
beta-hydroxyisovalerate	1.02	1.22	1.03
beta-hydroxyisovaleroylcarnitine	1.09	1.02	0.90
betaine	0.87	1.11	0.94
beta-muricholate	1.42	1.75	2.26
beta-sitosterol	1.08	0.94	0.91
bilirubin	0.37	1.17	0.85
biliverdin	0.90	1.09	1.02
butenoylcarnitine (C4:1)	0.76	0.85	1.53
butyrylcarnitine (C4)	0.97	0.83	1.42
butyrylglycine (C4)	0.68	0.87	0.69
butyryl/isobutyryl CoA	0.63	0.61	1.27
campesterol	1.05	0.92	0.89
caproate (6:0)	1.03	1.12	1.23
caprylate (8:0)	1.33	0.97	1.44
carnitine	1.15	0.87	1.04
carnosine	1.59	0.81	0.97
catechol sulfate	1.55	0.78	0.87
CDP-choline	0.70	1.83	1.23
CDP-ethanolamine	0.74	1.52	1.13
ceramide (d18:1/17:0, d17:1/18:0)*	0.54	1.27	1.01
C-glycosyltryptophan	0.75	1.94	1.01
chenodeoxycholate	0.96	1.62	3.36
chiro-inositol	0.80	1.12	1.13
cholate	0.89	1.26	1.70
cholesterol	0.98	1.00	1.03
cholesterol sulfate	0.90	1.15	0.90
choline	1.04	1.21	0.94
cis-4-decenoate (10:1n6)*	1.18	0.79	1.52
cis-4-decenoylcarnitine (C10:1)	1.62	0.71	1.36
citrate	0.97	1.10	1.01
citrulline	1.06	0.83	1.16
CMP	0.85	2.00	1.04
CoA	1.12	2.45	1.81
CoA-glutathione*	0.86	1.09	0.97
corticosterone	1.32	0.87	0.89
creatine	1.09	0.94	1.04
creatine phosphate	1.12	1.52	1.05
creatinine	1.09	0.85	1.04
cystathionine	1.06	1.00	1.10
cysteine	0.85	1.20	0.77
cysteine-glutathione disulfide	1.46	0.91	0.85
cysteinylglycine	0.38	1.29	0.73
cystine	0.99	0.91	0.91
cytidine	0.86	1.16	0.95
cytidine 5^-monophospho-N-acetylneuraminic acid	0.90	1.34	0.93
cytidine diphosphate	0.85	1.80	0.86
cytosine	0.88	1.17	1.11
daidzein	1.61	0.70	0.55
daidzein sulfate (2)	1.81	0.67	0.32
dCMP	0.77	1.37	0.96
decanoylcarnitine (C10)	1.52	0.84	1.70
dehydroascorbate	1.10	0.82	0.78
deoxycarnitine	0.99	0.96	0.94
diacylglycerol (16:1/18:2 [2], 16:0/18:3 [1])*	2.05	0.87	0.93
dihomolinoleate (20:2n6)	1.22	0.93	1.24
dihomolinolenate (20:3n3 or 3n6)	1.08	1.01	1.68
dihomo-linolenoylcarnitine (C20:3n3 or 6)*	2.52	1.36	1.93
dihomo-linoleoylcarnitine (C20:2)*	1.78	1.91	2.83
dihydroorotate	0.86	0.94	1.02
dihydroxyacetone phosphate (DHAP)	0.96	0.86	1.00
dimethylarginine (ADMA + SDMA)	1.01	0.94	1.13
dimethylglycine	0.96	1.05	0.98
dimethylmalonic acid	0.97	1.02	0.96
docosadienoate (22:2n6)	0.82	1.23	1.16
docosadienoylcarnitine (C22:2)*	0.76	2.73	4.02
docosahexaenoate (DHA; 22:6n3)	0.90	1.16	2.21
docosahexaenoylcarnitine (C22:6)*	1.86	0.97	1.27
docosahexaenoyl ethanolamide	0.98	1.09	1.04
docosapentaenoate (DPA; 22:5n3)	1.03	1.00	1.86
docosapentaenoate (n6 DPA; 22:5n6)	0.91	1.03	2.37
docosapentaenoylcarnitine (C22:5n3)*	3.92	0.89	1.37
docosapentaenoylcarnitine (C22:5n6)*	2.66	0.84	1.91
docosatrienoylcarnitine (C22:3)*	1.10	1.54	2.81
dodecadienoate (12:2)*	1.08	0.85	1.23
eicosapentaenoate (EPA; 20:5n3)	1.10	0.93	1.49
eicosenoate (20:1n9 or 1n11)	1.11	1.04	1.39
eicosenoylcarnitine (C20:1)*	1.24	1.32	2.19
enterolactone sulfate	3.98	1.48	0.65
equol glucuronide	1.03	0.89	1.15
equol sulfate	3.18	1.12	0.78
ergothioneine	0.93	0.94	1.21
erucate (22:1n9)	1.13	1.02	1.29
erucoylcarnitine (C22:1)*	0.74	1.09	1.57
erythritol	0.98	1.11	1.00
erythronate*	0.81	1.71	0.93
erythrose 4-phosphate	0.31	0.85	0.58
ethyl beta-glucopyranoside	0.90	0.53	0.69
ethylmalonate	1.31	1.11	1.17
FAD	1.20	0.86	0.97
ferulic acid 4-sulfate	1.22	1.20	1.53
FMN	1.16	0.93	0.96
fructose	1.28	1.25	1.34
fructose 1,6-bisphosphate	1.37	1.05	0.88
fructosyllysine	1.38	0.74	1.20
fumarate	0.90	1.30	1.01
galactonate	0.67	1.73	0.93
galactose 1-phosphate	0.74	1.08	0.96
gamma-glutamyl-epsilon-lysine	0.74	2.02	1.16
gamma-glutamylglutamate	0.65	1.99	1.07
gamma-glutamylglutamine	0.80	1.09	1.09
gamma-glutamylhistidine	0.77	1.09	1.08
gamma-glutamylisoleucine*	0.69	1.20	0.77
gamma-glutamylleucine	0.88	1.45	0.98
gamma-glutamylphenylalanine	0.73	1.39	1.09
gamma-glutamylthreonine	0.66	1.16	1.22
gamma-glutamylvaline	0.88	1.26	0.98
gamma-tocopherol/beta-tocopherol	1.28	1.00	0.92
gamma-tocotrienol	0.93	1.18	1.18
gluconate	1.34	1.18	1.04
glucosamine-6-phosphate	0.95	0.81	0.92
glucose	1.32	0.75	1.09
glucose 6-phosphate	0.97	0.83	0.90
glucuronate	0.86	1.57	1.06
glutamate	1.01	1.03	1.00
glutamate, gamma-methyl ester	1.00	1.01	1.08
glutamine	1.09	0.75	1.03
glutamine_degradant*	3.88	1.25	0.48
glutarate (C5-DC)	1.25	1.75	1.08
glutathione, oxidized (GSSG)	0.88	1.20	1.01
glutathione, reduced (GSH)	0.73	1.96	1.10
glycerate	1.09	1.02	0.85
glycerol	1.18	0.94	1.01
glycerol 3-phosphate	1.06	0.96	1.10
glycerophosphoethanolamine	0.87	1.42	1.02
glycerophosphoglycerol	0.80	1.04	1.11
glycerophosphoinositol*	1.10	1.34	0.90
glycerophosphorylcholine (GPC)	0.78	1.19	0.97
glycerophosphoserine*	0.65	1.28	0.62
glycine	0.84	1.06	1.09
glycochenodeoxycholate	0.46	0.66	1.32
glycocholate	0.61	0.82	1.43
glycosyl-N-palmitoyl-sphingosine (d18:1/16:0)	0.64	2.61	1.39
glycosyl-N-stearoyl-sphingosine (d18:1/18:0)	0.52	1.05	0.80
glycylleucine	1.21	1.19	1.02
glycylvaline	1.05	1.18	0.97
guaiacol sulfate	1.29	0.81	1.09
guanidinoacetate	0.88	1.36	0.87
guanine	0.74	1.50	0.94
guanosine	0.97	1.12	1.03
gulonate*	1.00	1.41	0.90
heme	1.29	0.99	1.14
heneicosapentaenoate (21:5n3)	1.20	0.53	0.71
heptanoate (7:0)	1.33	0.85	1.01
hexadecadienoate (16:2n6)	1.15	0.78	1.20
hexadecanedioate (C16)	1.02	1.30	1.33
hexadecatrienoate (16:3n3)	1.50	0.80	1.01
hexanoylcarnitine (C6)	1.26	0.72	1.35
hexanoyltaurine	2.67	0.82	0.86
hippurate	0.93	1.04	0.99
histamine	1.23	0.77	1.23
histidine	1.17	0.81	0.98
histidine betaine (hercynine)*	1.07	0.73	1.42
histidine methyl ester	0.99	1.14	0.84
homoarginine	0.93	0.86	1.35
homocitrulline	0.51	0.99	1.05
homostachydrine*	0.64	1.61	1.25
hydroquinone sulfate	1.51	0.76	0.58
hydroxy-N6,N6,N6-trimethyllysine*	1.16	0.65	1.22
hydroxypalmitoyl sphingomyelin (d18:1/16:0(OH))	0.96	1.62	0.89
hydroxyproline	0.97	1.08	1.02
hypotaurine	1.31	1.08	0.68
hypoxanthine	1.12	0.99	1.04
imidazole lactate	1.08	0.94	0.86
imidazole propionate	0.97	1.52	1.82
indoleacetate	1.26	0.73	1.26
indoleacrylate	1.07	0.73	0.98
indolelactate	1.15	1.07	1.11
indolepropionate	0.92	0.80	1.15
inosine	1.08	0.88	0.98
inosine 5^-monophosphate (IMP)	2.11	0.58	1.63
inositol 1-phosphate (I1P)	1.04	1.22	1.13
isoleucine	0.97	1.20	0.95
isoleucylglycine	0.89	1.23	1.05
isovalerylglycine	0.71	1.08	1.11
kynurenate	2.19	1.83	1.40
kynurenine	1.29	1.62	1.13
lactate	1.11	1.03	1.04
lactobacillic acid	1.00	0.95	2.24
laurylcarnitine (C12)	1.30	1.09	1.99
leucine	1.04	1.20	0.96
leucylalanine	1.00	1.09	0.92
leucylglutamine*	1.10	1.18	0.80
leucylglycine	1.06	1.13	0.93
lignoceroylcarnitine (C24)*	0.90	0.91	1.49
lignoceroyl sphingomyelin (d18:1/24:0)	0.87	1.05	1.14
linoleate (18:2n6)	1.41	0.76	1.11
linolenate (18:3n3 or 3n6)	1.71	0.80	1.05
linolenoylcarnitine (C18:3)*	2.99	0.95	1.04
linoleoyl-arachidonoyl-glycerol (18:2/20:4) [2]*	0.90	0.88	1.19
linoleoylcarnitine (C18:2)*	2.48	1.06	1.33
linoleoylcholine*	0.84	1.26	1.46
linoleoyl ethanolamide	1.35	0.89	1.01
lysine	0.99	0.85	1.17
lyxonate	0.80	1.48	1.25
malate	0.92	1.24	1.05
maleate	0.73	1.33	1.09
malonate	1.13	1.07	0.94
malonylcarnitine	1.40	0.79	0.99
maltitol/lactitol/cellobiotol/palatinol	1.10	0.94	1.06
maltose	1.01	0.86	0.89
maltotetraose	1.10	0.98	0.83
maltotriose	1.11	0.93	0.91
mannitol/sorbitol	2.27	1.62	1.48
mannonate*	0.62	1.31	1.08
mannose	1.08	0.87	1.11
mannose 6-phosphate	0.97	0.84	0.95
margarate (17:0)	1.06	1.02	1.25
margaroylcarnitine (C17)*	1.79	1.32	1.92
meadoylcarnitine (C20:3n9)*	0.46	1.19	1.49
methionine	1.01	1.06	0.93
methionine sulfoxide	1.15	1.02	0.90
methyl-4-hydroxybenzoate sulfate	0.46	4.96	6.37
methyl glucopyranoside (alpha + beta)	0.95	1.14	0.84
methylmalonate (MMA)	1.31	1.45	1.14
methylphosphate	1.13	0.98	0.96
methylsuccinate	1.15	0.91	1.43
myo-inositol	1.34	0.76	0.99
myristoleate (14:1n5)	0.85	0.98	1.40
myristoleoylcarnitine (C14:1)*	1.50	1.03	2.03
myristoylcarnitine (C14)	1.56	1.20	2.06
N1-Methyl-2-pyridone-5-carboxamide	1.08	1.22	0.93
(N(1) + N(8))-acetylspermidine	0.50	1.49	1.05
N2-acetyllysine	0.60	1.11	1.26
N-(2-hydroxypalmitoyl)-sphingosine (d18:1/16:0(2OH))	0.72	1.17	0.91
N4-acetylcytidine	0.76	1.19	1.04
N6-acetyllysine	1.39	0.76	1.16
N6-carbamoylthreonyladenosine	0.86	1.12	0.93
N6-carboxymethyllysine	1.47	0.71	1.09
N6-methyllysine	1.04	1.06	0.98
N6,N6,N6-trimethyllysine	0.93	0.93	1.24
N6-succinyladenosine	1.17	1.18	0.87
N-acetyl-1-methylhistidine*	0.47	1.17	0.56
N-acetylalanine	0.90	1.01	1.01
N-acetylarginine	0.88	1.01	1.21
N-acetylasparagine	1.13	1.23	1.34
N-acetylaspartate (NAA)	1.14	1.08	1.08
N-acetyl-aspartyl-glutamate (NAAG)	0.42	1.39	1.08
N-acetyl-glucosamine 1-phosphate	0.74	1.75	1.16
N-acetylglucosamine 6-phosphate	0.72	1.67	1.07
N-acetylglucosamine/N-acetylgalactosamine	0.60	1.61	0.77
N-acetylglucosaminylasparagine	0.94	1.48	0.92
N-acetylglutamate	0.72	1.09	1.07
N-acetylglutamine	0.99	1.04	1.18
N-acetylglycine	0.59	1.17	1.51
N-acetylhistamine	1.46	0.87	1.41
N-acetyl-isoputreanine	0.85	1.54	0.63
N-acetylkynurenine (2)	1.16	1.50	1.02
N-acetylleucine	1.18	1.20	1.12
N-acetylmethionine	1.04	1.03	1.02
N-acetylmethionine sulfoxide	1.18	1.07	1.10
N-acetylneuraminate	1.21	0.81	1.05
N-acetylphenylalanine	0.87	1.24	1.01
N-acetylputrescine	0.45	1.29	1.27
N-acetylserine	1.14	1.04	0.99
N-acetyltaurine	0.96	1.21	1.10
N-acetylthreonine	1.06	0.98	1.01
N-acetyltyrosine	0.78	1.18	1.03
NAD+	1.21	0.85	1.18
N-arachidonoyltaurine	0.62	1.37	1.61
N-delta-acetylornithine	0.97	0.93	1.28
nervonate (24:1n9)*	0.84	1.54	2.15
nervonoylcarnitine (C24:1)*	1.19	1.21	1.52
N-formylmethionine	0.96	1.04	0.98
N-glycolylneuraminate	1.08	1.00	0.97
nicotinamide	1.03	0.95	1.00
nicotinamide ribonucleotide (NMN)	1.23	0.78	1.13
nicotinamide riboside	1.22	1.15	1.25
nisinate (24:6n3)	1.39	0.89	2.07
N-linoleoyltaurine*	1.27	1.05	1.31
N-methyl-GABA	1.75	1.00	0.86
N-myristoyltaurine*	0.53	0.88	1.21
N,N-dimethylalanine	0.26	0.83	1.27
N,N-dimethyl-pro-pro	0.97	1.08	1.04
N,N,N-trimethyl-5-aminovalerate	0.75	1.21	1.66
N,N,N-trimethyl-alanylproline betaine (TMAP)	1.13	0.73	1.04
N-oleoyltaurine	0.85	1.16	1.28
nonadecanoate (19:0)	1.00	1.09	1.31
nonanoylcarnitine (C9)	1.07	0.79	1.33
N-palmitoyl-sphingadienine (d18:2/16:0)*	0.70	1.64	0.96
N-palmitoyl-sphinganine (d18:0/16:0)	0.43	1.93	1.12
N-palmitoyl-sphingosine (d18:1/16:0)	0.78	1.66	1.09
N-palmitoyltaurine	0.81	1.10	1.24
N-stearoyl-sphingosine (d18:1/18:0)*	0.97	1.10	0.99
N-stearoyltaurine	0.80	1.27	1.27
octadecenedioate (C18:1-DC)	1.03	0.99	1.73
octanoylcarnitine (C8)	1.45	0.78	1.61
oleate/vaccenate (18:1)	1.30	0.83	1.29
oleoyl-arachidonoyl-glycerol (18:1/20:4) [2]*	0.97	0.91	1.34
oleoylcarnitine (C18:1)	2.08	1.04	1.65
oleoylcholine	0.76	1.41	1.62
oleoyl CoA	1.78	0.94	1.42
oleoyl ethanolamide	0.95	1.32	1.08
oleoyl-linoleoyl-glycerol (18:1/18:2) [1]	1.30	0.77	1.03
O-methyltyrosine	0.92	1.19	0.95
ophthalmate	0.59	1.79	1.21
ornithine	0.85	1.21	1.06
orotate	0.75	1.39	0.93
orotidine	0.92	1.25	1.00
O-sulfo-L-tyrosine	0.71	1.55	0.93
oxalate (ethanedioate)	1.06	1.26	1.04
oxindolylalanine	1.36	1.01	0.97
palmitate (16:0)	1.06	0.94	1.09
palmitoleate (16:1n7)	1.40	0.94	1.20
palmitoleoylcarnitine (C16:1)*	1.65	1.14	1.99
palmitoloelycholine	0.62	1.18	1.76
palmitoylcarnitine (C16)	2.37	1.31	1.91
palmitoylcholine	0.73	1.41	1.72
palmitoyl CoA	1.49	0.84	1.32
palmitoyl dihydrosphingomyelin (d18:0/16:0)*	0.69	1.27	1.06
palmitoyl-docosahexaenoyl-glycerol (16:0/22:6) [1]*	0.73	0.84	1.43
palmitoyl-docosahexaenoyl-glycerol (16:0/22:6) [2]*	0.81	0.79	1.48
palmitoyl ethanolamide	0.99	1.17	1.12
palmitoyl-linoleoyl-glycerol (16:0/18:2) [2]*	1.44	0.78	0.98
palmitoyl sphingomyelin (d18:1/16:0)	0.80	1.24	1.01
pantetheine	0.93	0.82	0.91
pantothenate (Vitamin B5)	1.21	0.97	0.95
p-cresol glucuronide*	0.65	1.58	1.50
pentadecanoylcarnitine (C15)*	2.20	1.48	2.32
phenol sulfate	1.51	0.89	0.83
phenylacetylglycine	0.84	1.28	1.39
phenylalanine	0.98	1.27	1.00
phenylalanylalanine	0.99	1.18	0.76
phenylalanylglycine	0.91	1.27	0.92
phenyllactate (PLA)	0.90	1.02	1.47
phosphate	1.09	0.99	1.03
phosphocholine	0.95	1.20	1.11
phosphoenolpyruvate (PEP)	1.43	0.98	0.84
phosphoethanolamine (PE)	0.76	1.47	0.97
phosphopantetheine	1.68	1.36	1.36
phytosphingosine	0.81	1.03	1.08
pipecolate	0.63	1.19	1.40
proline	1.07	1.06	0.91
prolylglycine	0.90	1.03	1.05
prolylhydroxyproline	0.79	1.70	0.92
propionylcarnitine (C3)	1.30	0.92	1.26
pseudouridine	0.88	1.16	0.99
putrescine	0.25	1.17	1.19
pyridoxal	1.16	0.97	0.89
pyridoxal phosphate	1.15	1.16	0.96
pyridoxamine	1.25	0.91	0.93
pyridoxamine phosphate	1.09	0.87	0.98
pyridoxate	1.38	1.03	1.08
pyrraline	1.00	0.57	0.91
pyruvate	0.39	1.88	0.99
quinolinate	0.77	1.91	0.63
(R)-3-hydroxybutyrylcarnitine	0.83	1.55	2.21
retinol (Vitamin A)	0.88	1.28	0.83
ribitol	1.38	1.15	0.98
ribonate	0.74	0.99	1.01
ribose	1.06	1.22	1.05
ribose 1-phosphate	1.08	1.01	1.02
ribulose/xylulose	1.11	1.06	1.03
ribulose/xylulose 5-phosphate	0.69	0.87	0.82
S-(1,2-dicarboxyethyl)glutathione	0.68	2.67	1.18
(S)-3-hydroxybutyrylcarnitine	0.87	0.96	1.33
S-adenosylhomocysteine (SAH)	1.01	1.05	0.95
S-adenosylmethionine (SAM)	0.86	1.08	1.04
salicylate	0.91	1.72	1.26
sarcosine	0.60	0.93	0.74
sebacate (C10-DC)	1.13	0.88	1.07
sedoheptulose	0.83	1.32	1.05
sedoheptulose-7-phosphate	0.80	1.34	0.98
serine	0.86	1.05	1.38
serotonin	0.98	0.87	1.11
S-lactoylglutathione	1.06	1.25	1.13
S-methylcysteine	0.74	1.04	1.09
S-methylglutathione	0.79	1.38	1.09
spermidine	0.76	1.97	1.30
spermine	3.31	10.21	7.28
sphingadienine	1.04	1.09	0.94
sphinganine	0.60	1.55	0.96
sphinganine-1-phosphate	0.72	1.69	1.07
sphingomyelin (d17:1/16:0, d18:1/15:0, d16:1/17:0)*	0.87	1.13	1.01
sphingomyelin (d18:0/18:0, d19:0/17:0)*	0.79	1.22	1.02
sphingomyelin (d18:0/20:0, d16:0/22:0)*	0.52	1.17	1.05
sphingomyelin (d18:1/14:0, d16:1/16:0)*	0.99	1.11	0.93
sphingomyelin (d18:1/17:0, d17:1/18:0, d19:1/16:0)	0.87	1.10	0.99
sphingomyelin (d18:1/18:1, d18:2/18:0)	1.00	1.02	0.95
sphingomyelin (d18:1/19:0, d19:1/18:0)*	1.10	0.90	1.08
sphingomyelin (d18:1/20:0, d16:1/22:0)*	1.28	0.88	1.08
sphingomyelin (d18:1/20:1, d18:2/20:0)*	1.13	0.84	0.99
sphingomyelin (d18:1/21:0, d17:1/22:0, d16:1/23:0)*	0.97	0.87	1.30
sphingomyelin (d18:1/22:1, d18:2/22:0, d16:1/24:1)*	0.92	0.99	1.12
sphingomyelin (d18:1/22:2, d18:2/22:1, d16:1/24:2)*	0.80	1.37	1.07
sphingomyelin (d18:1/24:1, d18:2/24:0)*	0.78	1.21	1.03
sphingomyelin (d18:2/16:0, d18:1/16:1)*	0.77	1.43	1.02
sphingomyelin (d18:2/21:0, d16:2/23:0)*	0.95	0.88	1.23
sphingomyelin (d18:2/23:0, d18:1/23:1, d17:1/24:1)*	0.69	1.04	1.19
sphingomyelin (d18:2/23:1)*	0.64	1.17	1.12
sphingomyelin (d18:2/24:1, d18:1/24:2)*	0.83	1.54	1.03
sphingomyelin (d18:2/24:2)*	0.76	2.27	0.95
sphingosine	0.81	1.17	0.91
sphingosine 1-phosphate	0.86	1.27	1.07
stachydrine	0.72	1.38	1.24
stearate (18:0)	0.94	1.01	1.05
stearidonate (18:4n3)	1.25	0.93	1.30
stearoyl-arachidonoyl-glycerol (18:0/20:4) [2]*	0.92	1.13	1.04
stearoylcarnitine (C18)	1.48	1.11	1.66
stearoyl ethanolamide	1.04	1.00	1.00
stearoyl sphingomyelin (d18:1/18:0)	1.01	1.02	0.99
succinate	0.72	1.16	1.17
succinoyltaurine	1.00	1.03	1.07
succinylcarnitine (C4-DC)	1.14	0.68	0.99
sucrose	0.40	4.02	1.01
sulfate*	0.91	1.02	1.06
tartronate (hydroxymalonate)	1.11	0.88	0.88
taurine	1.00	1.04	0.98
taurocholate	1.37	2.43	1.06
taurocyamine	1.36	1.01	0.67
taurohyodeoxycholic acid	1.64	1.98	0.72
tetracosadienoylcarnitine (C24:2)*	0.89	1.24	1.35
tetradecadienoate (14:2)*	0.93	0.96	1.30
thiamin diphosphate	1.08	0.91	1.26
thiamin monophosphate	1.17	1.03	0.96
thiamin (Vitamin B1)	1.14	1.28	1.01
thioproline	2.27	2.85	1.70
threonate	0.88	1.06	0.96
threonine	0.97	1.02	1.15
thymidine	0.88	1.24	1.09
thymine	0.92	1.55	0.82
tiglyl carnitine (C5)	0.95	1.52	0.96
TMP	0.31	1.82	0.65
tricosanoyl sphingomyelin (d18:1/23:0)*	0.83	1.11	1.33
trigonelline (N^-methylnicotinate)	1.07	1.11	1.04
trimethylamine N-oxide	0.88	1.04	1.18
tryptophan	0.99	1.05	0.91
tyrosine	0.96	1.17	0.99
tyrosylglycine	0.88	1.35	0.99
UDP-glucose/UDP-galactose	0.91	1.07	0.99
UDP-glucuronate	0.53	1.99	0.99
UDP-N-acetylglucosamine/galactosamine	0.75	1.71	1.09
UMP	0.72	1.55	1.05
uracil	1.06	1.18	1.09
urate	0.95	1.51	0.87
urea	0.86	1.09	1.03
uridine	0.90	1.09	1.03
uridine 5^-diphosphate (UDP)	0.79	1.46	1.03
uridine 5^-triphosphate (UTP)	0.81	1.12	0.81
valine	0.96	1.22	0.96
valylglutamine	1.05	0.91	0.81
valylglycine	0.98	1.29	0.93
valylleucine	0.83	1.06	0.98
xanthine	0.90	1.32	0.91
xanthosine	0.76	1.72	1.01
ximenoylcarnitine (C26:1)*	0.99	1.16	1.67

Factors:

F1	Treatment:Control
F2	Treatment:Vehicle
F3	Treatment:WNK463