Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for (Study ST000876)

(Analysis AN001413)

Metabolite	Structure	F1	F2	F3	F4	F5	F6	F7	F8	F9	F10	F11	F12
Kynurenic Acid	ME226338	1.39	0.91	1.31	1.21	0.87	0.84	0.83	0.72	0.63	0.98	0.97	1.17
Hexanoylcarnitine	ME226330	1.34	1.19	1.02	1.06	0.92	0.69	1.02	0.92	1.02	1.22	0.70	0.95
Guanosine	ME226329	0.33	2.82	0.78	0.45	0.30	0.49	1.20	0.39	4.27	0.67	0.28	0.51
Proline	ME226260	0.90	1.36	1.31	0.80	0.89	1.15	0.76	0.92	0.97	1.00	1.08	0.93
Glyceraldehyde	ME226263	1.14	1.01	0.93	0.91	0.97	1.44	0.86	0.95	0.91	0.87	1.23	0.89
Aminodipic Acid	ME226305	1.04	1.48	1.55	0.72	1.01	0.98	1.00	0.81	0.90	0.94	0.98	0.79
Acetylcarnitine	ME226289	1.23	1.00	1.04	1.12	0.83	0.71	1.06	0.97	0.92	1.10	0.88	1.06
Carnitine	ME226273	1.14	0.89	1.02	0.88	0.87	1.03	1.01	1.10	0.99	1.09	0.84	1.07
Homogentisic acid	ME226313	2.16	0.73	0.96	0.89	1.41	0.72	0.68	0.85	1.28	0.99	0.49	0.92
4-Pyridoxic Acid	ME226336	1.34	1.41	1.07	0.50	0.50	0.46	0.41	0.33	1.82	1.43	0.89	1.42
Carnosine	ME226318	1.50	1.15	0.85	0.92	0.74	0.97	1.14	0.80	0.92	0.95	1.10	0.98
Chenodeoxycholic Acid	ME226284	1.69	1.65	0.75	0.82	0.55	1.13	0.77	0.96	1.33	0.79	0.63	0.96
Sucrose	ME226297	0.85	0.96	1.08	0.82	0.76	1.57	0.66	0.74	1.26	1.02	1.21	1.03
Arginine	ME226269	1.05	1.07	1.00	0.89	0.94	0.95	0.97	0.99	1.24	1.01	0.98	0.96
1-methylhistamine	ME226350	0.92	1.15	1.19	1.05	1.17	0.66	0.94	0.83	1.07	1.06	1.01	0.97
S-Adenosyl-L-Homocysteine	ME226346	0.91	0.71	1.00	1.23	0.86	1.63	0.99	1.13	0.89	0.80	1.38	0.74
Taurocholic Acid	ME226339	1.43	1.68	0.49	1.12	0.55	0.42	1.05	1.34	1.20	0.84	0.86	1.00
Leucine	ME226268	1.10	1.10	1.06	0.94	0.98	1.11	1.01	1.04	1.02	1.03	0.91	0.84
Lysine	ME226262	1.05	1.09	1.01	1.03	0.96	1.10	0.97	1.07	0.98	1.01	0.95	0.89
Trimethylamine-N-Oxide	ME226298	0.88	0.78	1.15	0.89	1.90	0.64	1.00	1.15	0.93	1.39	0.60	0.84
Pantothenic Acid	ME226314	0.95	0.91	0.80	0.91	1.07	1.08	1.02	1.09	0.93	1.00	0.82	1.21
Symmetric dimethylarginine	ME226306	0.92	0.84	0.91	0.93	1.09	1.06	1.00	1.18	1.09	1.12	0.87	0.99
UDP-Glucose	ME226310	2.96	0.28	0.62	0.35	0.58	3.00	0.26	1.35	0.51	NA	1.45	0.32
Propionylcarnitine	ME226311	1.19	1.27	1.03	0.91	0.76	0.99	1.04	1.10	0.86	1.12	0.75	0.99
Adenosine	ME226354	0.75	1.21	1.19	1.84	0.38	0.98	1.20	1.12	0.56	0.73	1.23	0.91
Cystathionine	ME226343	0.88	1.19	0.79	0.86	1.41	1.32	1.60	1.06	0.70	0.91	0.70	0.79
DimethylGlycine	ME226308	0.90	0.76	1.52	0.94	1.68	0.61	1.09	0.53	1.29	0.72	1.05	0.96
NAD	ME226349	3.65	0.13	0.55	0.26	0.44	3.70	0.28	1.30	0.40	0.40	1.14	0.37
Stearoyl Carnitine	ME226347	0.27	0.81	1.52	1.00	2.23	0.18	2.23	1.14	1.17	0.37	1.52	0.28
3-OH-DL-KYNURENINE	ME226335	0.88	1.14	1.18	1.11	1.06	0.93	1.07	1.11	0.81	0.99	1.06	0.82
Allantoin	ME226299	1.89	0.58	0.78	0.73	0.60	2.36	0.56	1.12	0.21	0.88	1.08	1.11
Betaine	ME226267	1.00	0.81	1.21	0.96	1.19	0.87	1.05	0.84	1.01	0.76	1.17	1.06
Palmitoyl Carnitine	ME226337	0.12	0.99	1.19	1.39	1.82	0.19	1.81	1.52	1.25	0.47	1.43	0.40
2-Aminoisobutyric acid	ME226302	1.21	1.12	0.82	1.33	1.14	1.17	1.22	0.84	0.73	0.98	0.77	0.83
Choline	ME226278	1.03	0.93	1.02	1.12	1.08	1.02	1.11	0.89	0.91	0.69	1.11	1.04
Adenine	ME226355	5.04	0.61	0.60	0.50	0.84	0.99	0.63	0.43	0.75	0.50	1.13	0.48
Hippuric acid	ME226293	0.20	0.33	3.21	1.74	0.32	0.24	0.21	1.74	0.75	0.31	2.74	0.59
Asymmetric dimethylarginine	ME226307	1.02	1.19	1.22	0.80	1.04	1.00	0.94	0.86	0.93	1.25	0.91	0.92
Xanthine	ME226295	1.08	0.82	1.05	1.14	0.99	1.22	0.96	0.96	0.79	1.27	1.06	0.83
Xanthosine	ME226332	1.52	0.89	0.87	0.99	0.75	1.42	0.82	1.00	0.74	1.06	1.21	0.87
L-5-Hydroxytryptophan	ME226340	1.15	1.15	0.96	1.17	0.96	0.88	1.29	0.66	0.97	1.36	0.63	0.91
GABA	ME226315	0.99	0.70	0.88	1.23	0.96	1.16	0.60	0.70	0.86	2.68	0.72	0.76
Dodecanoyl Carnitine	ME226326	1.33	1.46	1.06	1.33	0.98	0.54	1.14	0.95	1.34	1.19	0.70	0.50
Asparagine	ME226282	0.99	0.93	0.93	1.06	1.06	1.17	0.97	1.11	1.01	1.00	1.02	0.88
Succinate	ME226291	1.04	1.11	1.02	0.94	1.01	0.79	0.89	0.87	0.92	0.90	1.08	1.21
Isobutyrylcarnitine	ME226317	1.07	1.22	1.07	0.73	0.79	1.04	1.00	1.19	0.98	1.23	0.82	0.93
Glutathione	ME226360	1.17	0.54	1.29	0.63	NA	1.50	0.79	NA	1.08	NA	NA	NA
Aspartate	ME226288	1.16	0.77	0.78	0.90	1.28	1.33	0.80	1.16	0.96	0.89	1.13	0.92
Glycocholic Acid	ME226320	1.27	1.83	0.73	0.85	0.52	0.74	1.07	1.41	0.88	0.71	0.76	1.11
Normetanephrine	ME226353	1.09	0.97	1.04	1.11	0.80	0.75	1.02	0.72	1.01	1.09	1.07	1.17
L-Methionine	ME226286	1.20	1.01	1.11	0.97	1.15	1.14	0.87	0.88	0.98	0.88	1.09	0.86
3-Hydroxyanthranilic acid	ME226325	1.06	NA	0.81	1.09	1.27	1.20	1.04	1.33	0.44	1.30	0.83	0.82
Spermidine	ME226331	0.99	0.76	0.90	1.46	0.87	1.85	0.96	1.10	0.71	1.01	1.01	0.69
Hydroxyproline	ME226292	1.34	1.38	0.88	0.83	1.29	0.85	0.74	0.97	0.96	0.98	1.10	0.84
Isoleucine	ME226279	1.31	1.11	1.03	1.19	0.93	0.95	1.08	0.98	0.96	0.92	0.98	0.78
Uracil	ME226309	1.24	0.80	1.28	1.34	1.37	0.55	0.76	0.58	1.68	1.10	0.49	0.90
Tryptophan	ME226283	1.07	1.07	1.02	0.96	1.00	1.05	0.99	0.95	1.01	0.98	1.09	0.91
Gamma-Glutamylcysteine	ME226287	0.96	1.14	0.86	0.86	0.79	1.22	0.77	0.98	0.98	0.98	1.09	1.19
Cysteine	ME226277	1.11	1.00	1.06	0.97	0.91	1.05	0.96	1.02	0.98	0.99	0.97	0.99
D-Glucuronic acid	ME226300	1.20	1.49	1.12	0.87	0.95	0.79	0.68	0.81	0.70	1.22	0.82	1.17
Tyrosine	ME226265	0.96	1.15	0.97	0.96	0.95	0.93	0.94	0.96	1.09	1.21	1.06	0.91
Phenylalanine	ME226276	1.15	1.03	0.96	0.98	1.04	1.16	0.93	0.94	1.03	0.95	1.01	0.91
Threonine	ME226266	1.16	1.08	1.07	1.03	0.97	0.96	1.11	0.94	0.84	0.93	1.08	0.92
Creatinine	ME226272	0.88	0.97	1.12	0.94	1.01	0.78	1.04	1.12	1.10	1.07	0.95	1.01
Hypoxanthine	ME226294	1.05	0.75	1.08	0.79	1.03	1.29	0.90	1.28	0.82	1.19	1.04	0.89
AMP	ME226342	2.26	0.47	0.88	0.65	0.57	2.46	0.34	1.24	0.82	0.61	1.65	0.52
Serine	ME226271	0.80	0.74	0.72	1.02	1.61	1.11	1.34	1.33	1.45	1.41	0.60	0.43
Creatine	ME226270	1.29	1.07	0.85	1.08	0.81	1.47	1.15	1.02	0.83	0.94	0.83	0.83
Taurine	ME226264	1.19	0.82	1.02	0.94	1.02	1.18	0.88	1.13	0.62	0.93	1.18	1.04
L-Kynurenine	ME226304	1.10	1.11	1.05	1.00	1.04	1.03	0.97	0.87	0.99	0.99	1.01	0.92
Isovalerylcarnitine	ME226328	1.02	1.56	1.09	0.93	0.83	0.89	1.07	1.06	1.01	1.19	0.79	0.78
Glycine	ME226261	0.89	0.86	0.92	0.69	1.37	0.97	0.99	1.30	1.24	0.99	1.07	0.85
Taurochenodeoxycholic Acid	ME226323	1.73	2.04	0.47	1.00	0.44	0.53	1.09	1.49	0.95	0.54	1.02	0.85
Alanine	ME226257	0.91	1.01	0.93	0.95	1.05	1.03	0.85	1.13	0.98	1.06	1.09	1.00
Cytosine	ME226334	1.06	0.32	2.99	0.36	0.26	0.38	0.22	0.24	0.55	0.62	1.17	2.42
Histidine	ME226274	1.13	1.07	1.04	0.93	0.94	1.06	0.92	0.93	1.03	1.02	1.11	0.90
Guanidinoacetic Acid	ME226301	0.98	0.92	1.47	0.71	1.44	0.67	0.85	1.22	1.26	0.89	1.16	0.72
S-5-Adenosyl-L-Methionine Chloride	ME226303	0.51	0.61	1.47	0.87	0.41	1.77	0.39	1.37	1.37	0.89	1.90	0.71
5-Hydroxyindole-3-acetic acid	ME226333	1.15	0.65	1.51	1.08	0.82	0.87	0.61	1.09	1.23	0.77	0.86	1.19
Decanoylcarnitine	ME226321	1.29	1.12	1.04	0.98	1.01	0.68	1.05	1.00	1.18	1.21	0.70	0.88
Acetoacetic acid	ME226259	1.58	1.27	1.00	1.03	1.04	0.59	1.10	0.75	1.31	1.31	0.55	0.74
Cytidine	ME226316	1.16	0.95	0.98	0.95	0.86	0.86	1.12	1.04	0.99	1.17	0.80	1.06
deoxycytidine	ME226322	1.20	1.27	1.03	0.98	0.81	0.99	1.03	1.00	0.83	1.03	0.83	1.00
Myristoyl Carnitine	ME226344	0.58	1.33	1.04	1.39	1.24	0.58	1.29	1.23	1.18	0.98	1.06	0.55
Glutamine	ME226256	1.05	1.05	1.09	0.97	1.08	0.86	0.93	1.00	1.07	1.05	1.03	0.91
Niacinamide	ME226324	0.96	0.91	1.11	1.21	0.93	0.93	1.32	1.67	0.69	0.46	1.23	0.79
Arachidyl Carnitine	ME226352	1.11	1.14	1.00	0.92	0.96	0.94	1.25	0.94	0.97	1.05	0.97	0.87
Ornithine	ME226275	1.18	1.20	0.87	1.08	1.00	1.08	0.93	0.98	0.67	0.98	1.29	0.87
Citrulline	ME226280	1.00	1.35	1.08	0.92	0.87	1.05	0.85	0.87	0.99	0.95	1.11	0.98
Sorbitol	ME226281	0.87	0.55	0.66	0.93	0.66	1.14	0.64	0.64	0.74	0.63	0.84	2.35
Octanoylcarnitine	ME226319	1.56	1.23	1.03	1.05	1.01	0.59	1.02	0.82	1.14	1.28	0.61	0.83
Myoinositol	ME226290	0.91	0.93	0.98	1.15	0.98	1.26	0.80	0.91	0.80	1.24	1.13	0.96
Neopterin	ME226348	NA	0.79	0.23	1.05	0.37	1.33	1.50	0.85	0.44	1.46	1.08	1.45
IMP	ME226341	1.80	0.76	1.14	0.51	0.72	2.58	0.44	1.07	0.98	0.68	1.41	0.46
Phosphoethanolamine	ME226296	0.92	0.93	1.32	0.98	1.07	0.89	1.00	0.83	1.01	0.81	1.18	1.03
L-Glutamic Acid	ME226285	0.88	0.68	0.89	1.11	1.09	1.35	1.02	1.21	0.76	0.88	1.33	0.91
Valine	ME226258	1.02	1.26	1.14	1.08	0.98	1.07	0.99	0.91	0.91	0.91	1.05	0.84
D-Ribose 5-phosphate	ME226327	1.20	0.71	1.32	2.02	0.83	0.86	1.10	0.95	0.81	0.55	1.31	0.67
cAMP	ME226345	0.82	1.59	0.89	0.57	0.55	0.17	0.63	0.49	1.77	2.47	0.52	1.26
Inosine	ME226312	0.59	1.68	0.55	0.41	0.53	1.05	1.17	1.16	2.94	1.27	0.57	0.54

Factors:

F1	L-serine (mg/kg/day):100 \| time point (weeks):6
F2	L-serine (mg/kg/day):200 \| time point (weeks):52
F3	L-serine (mg/kg/day):200 \| time point (weeks):9
F4	L-serine (mg/kg/day):300 \| time point (weeks):12
F5	L-serine (mg/kg/day):400 \| time point (weeks):15
F6	L-serine (mg/kg/day):400 \| time point (weeks):18
F7	L-serine (mg/kg/day):400 \| time point (weeks):21
F8	L-serine (mg/kg/day):400 \| time point (weeks):30
F9	L-serine (mg/kg/day):400 \| time point (weeks):38
F10	L-serine (mg/kg/day):400 \| time point (weeks):44
F11	L-serine (mg/kg/day):50 \| time point (weeks):3
F12	L-serine (mg/kg/day):- \| time point (weeks):-

Data matrix