Clustering data with hclust algorithm for (Study ST002078)
(Analysis AN003387)| Metabolite | Structure | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 |
|---|---|---|---|---|---|---|---|---|---|
| dihydroorotate | ME478712 | 0.35 | 0.45 | 0.66 | NA | 0.83 | NA | 3.70 | NA |
| N-carbamoyl-L-aspartate | ME478720 | 0.45 | 0.64 | 1.03 | NA | 1.07 | NA | 2.81 | NA |
| CMP | ME478760 | 1.66 | 1.16 | 0.57 | NA | 0.78 | NA | 0.83 | NA |
| D-glyceraldehdye-3-phosphate | ME478715 | 1.25 | 1.10 | 1.10 | NA | 1.44 | NA | 1.11 | NA |
| glutathione | ME478757 | 1.23 | 1.06 | 0.96 | NA | 1.61 | NA | 1.14 | NA |
| thymine | ME478693 | 0.97 | 1.09 | 0.94 | NA | 1.16 | NA | 1.27 | NA |
| N-acetyl-glucosamine-1/6-phosphate | ME478755 | 0.93 | 0.89 | 1.16 | NA | 1.22 | NA | 1.13 | NA |
| ornithine | ME478701 | 0.96 | 0.97 | 1.28 | NA | 1.29 | NA | 1.08 | NA |
| coenzyme A | ME478807 | 0.88 | 0.98 | 1.03 | NA | 1.41 | NA | 1.03 | NA |
| xanthosine | ME478751 | 0.91 | 0.88 | 0.96 | NA | 1.22 | NA | 1.03 | NA |
| CDP-ethanolamine | ME478783 | 1.29 | 0.94 | 0.91 | NA | 0.96 | NA | 0.90 | NA |
| UMP | ME478761 | 1.36 | 1.08 | 0.75 | NA | 1.00 | NA | 0.81 | NA |
| IDP | ME478780 | 1.14 | 0.73 | 1.18 | NA | 1.11 | NA | 0.85 | NA |
| Myristoyl/tetradecanoyl-CoA | ME478812 | 1.13 | 0.97 | 1.15 | NA | 0.83 | NA | 0.92 | NA |
| Decanoyl-CoA | ME478811 | 1.05 | 1.21 | 0.86 | NA | 1.00 | NA | 0.88 | NA |
| succinyl-CoA/methylmalonyl-CoA | ME478810 | 0.94 | 0.88 | 1.11 | NA | 1.17 | NA | 0.90 | NA |
| L-arginino-succinate | ME478753 | 0.98 | 1.05 | 1.14 | NA | 0.98 | NA | 0.85 | NA |
| FMN | ME478784 | 0.90 | 1.04 | 1.09 | NA | 1.05 | NA | 0.92 | NA |
| Thiamine pyrophosphate | ME478778 | 0.89 | 0.97 | 1.12 | NA | 1.08 | NA | 0.93 | NA |
| GMP | ME478766 | 1.06 | 1.00 | 0.80 | NA | 1.17 | NA | 0.97 | NA |
| NADH | ME478803 | 1.00 | 1.02 | 0.92 | NA | 1.12 | NA | 0.94 | NA |
| NADPH | ME478806 | 1.02 | 0.97 | 0.89 | NA | 1.16 | NA | 0.97 | NA |
| NADP+ | ME478805 | 1.11 | 0.95 | 0.98 | NA | 1.04 | NA | 0.92 | NA |
| Sedoheptulose bisphosphate | ME478768 | 1.08 | 0.96 | 0.98 | NA | 1.05 | NA | 0.93 | NA |
| UDP-D-glucose | ME478797 | 1.09 | 1.00 | 0.99 | NA | 1.00 | NA | 0.92 | NA |
| UDP-D-glucuronate | ME478798 | 1.12 | 0.99 | 0.96 | NA | 1.03 | NA | 0.90 | NA |
| ADP-D-glucose | ME478799 | 1.10 | 0.95 | 1.03 | NA | 1.04 | NA | 0.88 | NA |
| CDP-choline | ME478792 | 1.08 | 0.91 | 1.03 | NA | 1.08 | NA | 0.91 | NA |
| Phenol Red | ME478681 | 0.97 | 0.95 | 1.08 | NA | 1.06 | NA | 0.93 | NA |
| 4-phosphopantetheine | ME478765 | 1.02 | 0.97 | 1.03 | NA | 1.09 | NA | 0.90 | NA |
| acetyl-CoA | ME478809 | 1.02 | 1.01 | 1.04 | NA | 1.05 | NA | 0.87 | NA |
| chlorpropamide | ME478680 | 1.03 | 1.03 | 1.02 | NA | 1.01 | NA | 0.92 | NA |
| FAD | ME478808 | 1.01 | 0.96 | 1.02 | NA | 1.05 | NA | 0.95 | NA |
| folate | ME478781 | 1.04 | 0.99 | 0.99 | NA | 1.04 | NA | 0.93 | NA |
| 3-phosphoglycerate | ME478727 | 1.13 | 1.06 | 0.86 | NA | 1.01 | NA | 0.94 | NA |
| aspartate (standard) | ME478679 | 1.03 | 0.99 | 0.96 | NA | 0.94 | NA | 0.90 | NA |
| Octulose Bisphosphate | ME478774 | 1.09 | 1.06 | 0.99 | NA | 0.95 | NA | 0.91 | NA |
| UDP-N-acetyl-glucosamine | ME478800 | 1.17 | 1.06 | 0.94 | NA | 0.94 | NA | 0.89 | NA |
| CTP | ME478789 | 1.62 | 1.38 | 0.99 | NA | 1.00 | NA | 1.01 | NA |
| cytidine | ME478743 | 1.49 | 1.39 | 0.97 | NA | 0.95 | NA | 1.20 | NA |
| aspartate | ME478702 | 1.30 | 1.44 | 1.12 | NA | 1.08 | NA | 1.04 | NA |
| arginine | ME478718 | 1.21 | 1.30 | 1.04 | NA | 1.08 | NA | 1.09 | NA |
| D-gluconate | ME478732 | 1.23 | 1.38 | 1.08 | NA | 1.09 | NA | 1.22 | NA |
| lysine | ME478707 | 1.27 | 1.37 | 1.11 | NA | 0.96 | NA | 1.17 | NA |
| thiamine | ME478748 | 1.36 | 1.24 | 1.09 | NA | 1.01 | NA | 0.97 | NA |
| dTTP | ME478788 | 1.48 | 1.20 | 1.14 | NA | 1.18 | NA | 1.00 | NA |
| UTP | ME478790 | 1.38 | 1.20 | 1.18 | NA | 1.24 | NA | 1.00 | NA |
| dATP | ME478793 | 1.44 | 1.13 | 1.07 | NA | 1.17 | NA | 1.19 | NA |
| 2_3-Diphosphoglyceric acid | ME478749 | 1.49 | 1.26 | 1.05 | NA | 1.11 | NA | 1.09 | NA |
| phosphoenolpyruvate | ME478714 | 1.38 | 1.25 | 1.02 | NA | 1.22 | NA | 1.12 | NA |
| fumarate | ME478687 | 0.92 | 1.17 | 1.31 | NA | 1.42 | NA | 1.04 | NA |
| malate | ME478703 | 0.96 | 1.16 | 1.40 | NA | 1.35 | NA | 1.10 | NA |
| maleic acid | ME478688 | 0.96 | 1.16 | 1.39 | NA | 1.32 | NA | 1.09 | NA |
| Acetyllysine | ME478729 | 0.85 | 0.97 | 1.65 | NA | 1.37 | NA | 1.08 | NA |
| Pyrophosphate | ME478721 | 0.93 | 1.05 | 1.51 | NA | 1.28 | NA | 1.14 | NA |
| D-sedoheptulose-1/7-phosphate | ME478752 | 1.11 | 1.39 | 1.24 | NA | 0.89 | NA | 1.04 | NA |
| dGDP/ADP | ME478779 | 1.13 | 1.27 | 1.25 | NA | 0.97 | NA | 1.05 | NA |
| nicotinate | ME478692 | 1.14 | 1.34 | 1.32 | NA | 0.99 | NA | 1.04 | NA |
| guanine | ME478711 | 1.03 | 1.24 | 1.46 | NA | 1.08 | NA | 1.19 | NA |
| lactate | ME478683 | 0.96 | 1.26 | 1.39 | NA | 1.01 | NA | 1.13 | NA |
| dCMP | ME478756 | 0.96 | 1.43 | 1.32 | NA | 1.20 | NA | 1.08 | NA |
| alanine/sarcosine | ME478682 | 0.94 | 1.34 | 1.23 | NA | 1.11 | NA | 0.99 | NA |
| citrate/isocitrate | ME478731 | 0.99 | 1.35 | 1.27 | NA | 1.07 | NA | 1.09 | NA |
| hexose-phosphate | ME478747 | 1.17 | 1.15 | 1.34 | NA | 1.33 | NA | 1.00 | NA |
| asparagine | ME478700 | 1.23 | 1.27 | 1.26 | NA | 1.11 | NA | 1.12 | NA |
| glutathione disulfide | ME478801 | 1.32 | 1.27 | 1.21 | NA | 1.10 | NA | 1.09 | NA |
| Hexose | ME478723 | 1.27 | 1.23 | 1.17 | NA | 1.17 | NA | 1.15 | NA |
| N-acetyl-glutamate | ME478730 | 1.18 | 1.28 | 1.19 | NA | 1.18 | NA | 1.12 | NA |
| N-Acetyl-L-alanine | ME478697 | 1.08 | 1.31 | 1.23 | NA | 1.14 | NA | 1.13 | NA |
| ribose | ME478710 | 1.10 | 1.28 | 1.27 | NA | 1.16 | NA | 1.10 | NA |
| leucine | ME478699 | 1.13 | 1.21 | 1.33 | NA | 1.21 | NA | 1.10 | NA |
| valine | ME478689 | 1.11 | 1.25 | 1.36 | NA | 1.21 | NA | 1.03 | NA |
| hypoxanthine | ME478704 | 1.25 | 1.20 | 1.23 | NA | 1.24 | NA | 1.07 | NA |
| 4-Pyridoxic acid | ME478725 | 1.21 | 1.15 | 1.22 | NA | 1.14 | NA | 1.11 | NA |
| isoleucine | ME478698 | 1.18 | 1.24 | 1.29 | NA | 1.16 | NA | 1.08 | NA |
| tyrosine | ME478724 | 1.21 | 1.21 | 1.28 | NA | 1.21 | NA | 1.06 | NA |
| hydroxyproline/Aminolevulinate | ME478696 | 1.16 | 1.19 | 1.22 | NA | 1.20 | NA | 1.16 | NA |
| glutamine | ME478706 | 1.18 | 1.19 | 1.30 | NA | 1.18 | NA | 1.14 | NA |
| methionine | ME478709 | 1.17 | 1.22 | 1.26 | NA | 1.21 | NA | 1.13 | NA |
| tryptophan | ME478733 | 1.17 | 1.19 | 1.27 | NA | 1.22 | NA | 1.13 | NA |
| 4-aminobutyrate | ME478684 | 1.07 | 1.13 | 1.25 | NA | 1.33 | NA | 1.19 | NA |
| glutamate | ME478708 | 1.06 | 1.12 | 1.28 | NA | 1.36 | NA | 1.16 | NA |
| N-acetyl-glutamine | ME478728 | 1.10 | 1.21 | 1.23 | NA | 1.35 | NA | 1.05 | NA |
| 3-phospho-serine | ME478726 | 1.14 | 1.16 | 1.28 | NA | 1.32 | NA | 1.10 | NA |
| threonine/homoserine | ME478691 | 1.12 | 1.17 | 1.23 | NA | 1.24 | NA | 1.10 | NA |
| phenylalanine | ME478713 | 1.12 | 1.18 | 1.29 | NA | 1.24 | NA | 1.15 | NA |
| ribose-phosphate | ME478737 | 1.11 | 1.20 | 1.26 | NA | 1.29 | NA | 1.14 | NA |
| glucono-lactone | ME478722 | 1.24 | 1.07 | 1.12 | NA | 1.30 | NA | 1.08 | NA |
| GTP | ME478796 | 1.22 | 1.16 | 1.19 | NA | 1.28 | NA | 1.15 | NA |
| sn-glycerol-3-phosphate | ME478716 | 1.23 | 1.18 | 1.16 | NA | 1.27 | NA | 1.13 | NA |
| dGTP/ATP | ME478795 | 1.21 | 1.11 | 1.20 | NA | 1.32 | NA | 1.16 | NA |
| fructose-6-phosphate | ME478746 | 1.19 | 1.14 | 1.24 | NA | 1.28 | NA | 1.15 | NA |
| dCTP | ME478785 | 0.98 | 1.13 | 1.24 | NA | 1.26 | NA | 1.06 | NA |
| Pyroglutamic acid | ME478694 | 1.01 | 1.10 | 1.16 | NA | 1.21 | NA | 1.12 | NA |
| succinate/Methylmalonic acid | ME478690 | 1.07 | 1.11 | 1.17 | NA | 1.20 | NA | 1.11 | NA |
| ribulose-5-phosphate | ME478739 | 1.06 | 1.11 | 1.19 | NA | 1.00 | NA | 0.97 | NA |
| 4-phosphopantothenate | ME478754 | 1.05 | 1.05 | 1.15 | NA | 1.12 | NA | 0.95 | NA |
| S-adenosyl-L-homocysteine | ME478771 | 0.97 | 1.05 | 1.15 | NA | 1.13 | NA | 1.03 | NA |
| serine | ME478685 | 1.12 | 1.14 | 1.17 | NA | 1.11 | NA | 1.05 | NA |
| NAD+ | ME478802 | 1.12 | 1.06 | 1.06 | NA | 1.08 | NA | 1.01 | NA |
| acetyl-aspartate | ME478719 | 1.08 | 1.10 | 1.08 | NA | 1.12 | NA | 1.04 | NA |
| Ribose-5-phosphate | ME478738 | 1.05 | 1.10 | 1.07 | NA | 1.13 | NA | 0.98 | NA |
| D-glucarate | ME478735 | 1.13 | 1.11 | 1.28 | NA | 1.05 | NA | 1.13 | NA |
| Octulose 8/1P | ME478758 | 1.26 | 1.11 | 1.15 | NA | 1.11 | NA | 1.04 | NA |
| proline | ME478686 | 1.27 | 1.11 | 1.12 | NA | 1.08 | NA | 1.16 | NA |
| Xanthurenic acid | ME478734 | 0.92 | 1.77 | 1.37 | NA | 0.72 | NA | 1.20 | NA |
| dAMP | ME478763 | 1.29 | 1.22 | 0.95 | NA | 0.64 | NA | 0.89 | NA |
| dCDP | ME478772 | 0.85 | 1.38 | 1.26 | NA | 0.65 | NA | 0.85 | NA |
| dTMP | ME478759 | 1.12 | 1.35 | 1.07 | NA | 0.67 | NA | 0.79 | NA |
| GDP | ME478782 | 0.97 | 1.24 | 1.11 | NA | 0.75 | NA | 0.94 | NA |
| CDP | ME478776 | 1.54 | 1.79 | 1.09 | NA | 0.62 | NA | 0.92 | NA |
| DL-Pipecolic Acid | ME478695 | 1.32 | 1.59 | 1.10 | NA | 0.94 | NA | 1.00 | NA |
| dTDP | ME478775 | 1.44 | 1.43 | 1.13 | NA | 0.74 | NA | 0.93 | NA |
| UDP | ME478777 | 1.28 | 1.54 | 1.20 | NA | 0.73 | NA | 0.92 | NA |
| Cystine | ME478742 | 0.82 | 0.77 | 1.87 | NA | 1.13 | NA | 1.32 | NA |
| N-acetyl-L-ornithine | ME478717 | 0.73 | 0.76 | 1.68 | NA | 1.72 | NA | 1.10 | NA |
| Asp-Leu-Ser (DLS) | ME478764 | 0.82 | 0.80 | 1.55 | NA | 1.70 | NA | 1.13 | NA |
| Pro-Glu (PE) | ME478744 | 0.80 | 0.86 | 1.57 | NA | 1.61 | NA | 1.16 | NA |
| Val-Asp (VD) | ME478741 | 0.76 | 0.86 | 1.55 | NA | 1.63 | NA | 1.19 | NA |
| Ser-Asp (SD) | ME478736 | 0.76 | 0.71 | 1.40 | NA | 1.72 | NA | 1.07 | NA |
| Val-Asp-Pro-Val-Asn-Phe (VDPVNF) | ME478804 | 0.63 | 0.62 | 1.50 | NA | 1.61 | NA | 0.97 | NA |
| a-ketoglutarate | ME478705 | 0.84 | 0.95 | 1.32 | NA | 1.73 | NA | 1.12 | NA |
| Leu-Asp (LD) | ME478745 | 0.71 | 1.11 | 1.41 | NA | 1.54 | NA | 1.12 | NA |
| 6-phospho-D-gluconate | ME478750 | 0.67 | 0.94 | 1.22 | NA | 1.29 | NA | 0.88 | NA |
| cyclic-AMP | ME478762 | 0.77 | 0.78 | 1.25 | NA | 1.25 | NA | 0.95 | NA |
| Pro-Asp (PD) | ME478740 | 0.77 | 0.83 | 1.30 | NA | 1.39 | NA | 1.04 | NA |
| dUTP | ME478786 | 0.78 | 0.80 | 1.33 | NA | 1.09 | NA | 1.01 | NA |
| xanthosine-5-phosphate | ME478767 | 0.74 | 0.97 | 1.40 | NA | 1.03 | NA | 0.87 | NA |
| 5-phosphoribosyl-1-pyrophosphate | ME478773 | 0.63 | 0.46 | 1.32 | NA | 1.69 | NA | 0.90 | NA |
| Pro-Val-Asn-Phe (PVNF) | ME478787 | 0.62 | 0.71 | 1.34 | NA | 1.40 | NA | 0.92 | NA |
| His-Val-Asp-Asp (HVDD) | ME478791 | 0.55 | 0.73 | 1.41 | NA | 1.42 | NA | 0.89 | NA |
| Pro-Glu-Glu (PEE) | ME478769 | 0.55 | 0.66 | 1.38 | NA | 1.45 | NA | 0.95 | NA |
| Asp-Leu-His (DLH) | ME478770 | 0.56 | 0.65 | 1.25 | NA | 1.54 | NA | 1.00 | NA |
| Pro-Glu-Glu-Lys (PEEK) | ME478794 | 0.59 | 0.66 | 1.31 | NA | 1.55 | NA | 0.89 | NA |
Factors:
| F1 | Drug:Halofuginone |
| F2 | Drug:MMV1081413 |
| F3 | Drug:MMV1091186 |
| F4 | Drug:MMV1578884 |
| F5 | Drug:ND |
| F6 | Drug:OSM-S-106 |
| F7 | Drug:Pool |
| F8 | Drug:TCMDC-124553 |
