Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for (Study ST002218)

(Analysis AN003627)

Metabolite	Structure	F1	F2	F3	F4
cystathionine	ME537203	0.36	0.34	0.94	2.36
argininosuccinate	ME537173	1.97	1.98	0.03	0.02
succinyladenosine	ME537298	1.81	2.16	0.01	0.02
S-(2-succinyl)cysteine	ME537289	1.91	2.08	0.00	0.00
S-Succinylglutathione	ME537296	1.87	2.09	0.02	0.03
fumarate	ME537217	1.56	2.17	0.16	0.12
succinate	ME537297	1.62	1.92	0.31	0.15
choline	ME537191	1.19	2.28	0.35	0.18
NADH	ME537270	1.37	2.02	0.46	0.15
phosphoenolpyruvate	ME537284	1.34	2.01	0.34	0.31
SAICAR	ME537292	0.72	3.23	0.03	0.02
gamma-glutamylcysteine	ME537218	1.34	2.48	0.08	0.10
adenylosuccinate	ME537167	1.09	2.89	0.01	0.01
cysteate	ME537204	0.88	2.63	0.29	0.21
3-phosphoserine	ME537159	0.30	0.44	1.64	1.62
aspartate	ME537175	0.26	0.38	1.81	1.54
malate	ME537256	0.25	0.44	1.87	1.44
N-acetylglutamate	ME537264	0.34	0.38	1.98	1.30
phosphocreatine	ME537283	0.16	0.37	2.19	1.28
carnitine C5	ME537187	0.48	0.69	2.07	0.76
carnitine C4	ME537186	0.43	0.90	1.67	1.00
glutamate	ME537228	0.57	0.61	1.70	1.12
dCTP	ME537208	0.43	0.63	1.80	1.13
orotidine	ME537277	0.46	0.67	1.82	1.06
2-oxoglutarate	ME537158	0.67	0.74	1.49	1.10
dTTP	ME537213	0.58	0.75	1.60	1.07
N-acetylaspartylglutamate	ME537263	0.46	0.58	1.63	1.33
aconitate	ME537165	0.54	0.68	1.51	1.28
proline	ME537285	0.56	0.60	1.53	1.31
N-acetylaspartate	ME537262	0.24	0.27	3.15	0.34
carnitine C3	ME537185	0.17	0.27	2.57	0.99
ophthalmate	ME537274	0.07	0.05	2.76	1.13
carnitine C16	ME537182	0.62	2.22	0.83	0.33
carnitine C14	ME537180	0.37	2.34	0.95	0.34
carnitine C16:1	ME537183	0.28	2.53	0.84	0.34
methylthioadenosine	ME537258	0.92	0.90	1.07	1.12
citrate	ME537193	0.71	0.88	1.22	1.20
dTMP	ME537212	0.81	0.78	1.24	1.16
N-acetylserine	ME537268	0.56	0.92	1.38	1.15
CDP	ME537190	0.72	0.94	1.35	0.99
CTP	ME537200	0.66	0.99	1.45	0.90
2-hydroxyglutarate	ME537157	0.93	0.87	1.36	0.84
sedoheptulose 7-phosphate	ME537294	0.99	0.88	1.43	0.70
ketoleucine	ME537250	0.87	1.11	1.36	0.66
betaine	ME537178	0.64	1.12	1.48	0.76
acetyl-CoA	ME537164	0.77	1.18	1.19	0.86
CMP	ME537195	0.67	1.17	1.22	0.94
UTP	ME537309	0.69	1.12	1.36	0.83
cytidine	ME537206	0.71	1.19	1.34	0.76
pyruvate	ME537288	0.73	1.16	1.33	0.77
cytosine	ME537207	0.77	1.12	1.28	0.83
6-phosphogluconate	ME537163	0.77	1.05	1.34	0.85
ketovaline	ME537251	0.83	1.04	1.33	0.80
4-hydroxyphenyllactate	ME537160	1.09	0.96	1.15	0.81
gluconate	ME537224	0.92	0.89	1.26	0.93
N-carbamoylaspartate	ME537273	0.88	0.92	1.21	0.98
ATP	ME537176	0.89	1.03	1.19	0.89
phosphocholine	ME537282	0.80	0.98	1.23	0.99
UDP	ME537303	0.78	1.02	1.24	0.96
ornithine	ME537275	0.90	1.21	1.00	0.90
creatine	ME537198	0.92	1.15	1.08	0.85
NADPH	ME537272	0.85	1.13	1.12	0.90
UDP-glucose	ME537305	0.85	1.19	1.13	0.83
gamma-glutamylglutamate	ME537219	0.80	1.12	1.04	1.04
ADP	ME537168	0.98	1.00	1.07	0.94
4-hydroxyproline	ME537162	0.90	1.06	1.07	0.98
alanine	ME537170	0.87	1.00	1.14	1.00
gamma-glutamylproline	ME537220	0.96	1.26	0.82	0.96
citrulline	ME537194	1.14	1.17	0.79	0.90
glutamine	ME537229	1.02	1.18	0.91	0.89
methionine	ME537257	1.07	1.14	0.91	0.87
histidine	ME537241	1.06	1.09	0.86	1.00
S-adenosylmethionine	ME537291	1.07	1.07	0.93	0.93
glycerylphosphorylcholine	ME537233	1.02	1.23	1.25	0.50
2/3-phosphoglycerate	ME537156	1.05	1.18	1.02	0.75
homocysteine	ME537244	1.06	1.15	1.00	0.80
arginine	ME537172	1.09	1.24	0.96	0.72
leucine	ME537254	1.10	1.26	0.97	0.68
phenylalanine	ME537281	1.08	1.20	1.03	0.69
tyrosine	ME537302	1.08	1.22	1.01	0.69
valine	ME537310	1.07	1.23	1.02	0.68
cyclic ADP-ribose	ME537201	1.03	1.24	1.03	0.71
isoleucine	ME537249	1.05	1.20	1.04	0.71
pyroglutamate	ME537287	0.99	1.31	1.02	0.67
xanthine	ME537311	0.99	1.28	1.07	0.66
taurine	ME537299	0.90	1.27	1.07	0.75
carnosine	ME537189	0.97	1.29	1.05	0.70
creatinine	ME537199	0.94	1.28	1.06	0.71
pentose phosphate	ME537280	0.94	1.29	1.04	0.73
glucose	ME537225	0.92	1.14	1.17	0.76
pyridoxine	ME537286	0.94	1.22	1.15	0.69
NAD	ME537269	1.00	1.19	1.07	0.74
homocitrulline	ME537243	0.98	1.19	1.11	0.72
kynurenine	ME537252	0.99	1.20	1.09	0.71
AMP	ME537171	1.08	1.35	0.72	0.85
asparagine	ME537174	1.07	1.37	0.79	0.76
adenosine	ME537166	1.19	1.24	0.80	0.77
N-acetylneuranimic acid	ME537267	1.22	1.23	0.90	0.65
N,N-dimethylarginine	ME537259	1.20	1.31	0.84	0.65
xanthosine	ME537312	1.05	1.33	0.99	0.64
GDP-glucose	ME537223	1.08	1.30	1.02	0.60
tryptophan	ME537301	1.09	1.30	1.00	0.61
CMP-acetylneuraminate	ME537196	1.13	1.31	1.04	0.52
fructose 6-phosphate	ME537215	1.10	1.37	1.00	0.54
flavin adenine dinucleotide	ME537214	1.09	1.46	0.82	0.63
GMP	ME537237	1.15	1.40	0.78	0.67
inosine	ME537247	1.11	1.44	0.78	0.67
GDP	ME537221	1.09	1.34	0.89	0.67
homoarginine	ME537242	1.10	1.32	0.91	0.67
dihydroxyacetone phosphate	ME537211	1.08	1.32	0.89	0.72
threonine	ME537300	1.05	1.30	0.93	0.73
lysine	ME537255	1.09	1.41	0.93	0.57
glycine	ME537235	1.05	1.41	0.92	0.62
GTP	ME537238	1.06	1.44	0.89	0.61
serine	ME537295	1.03	1.38	0.91	0.67
UDP-GlcNac	ME537304	1.00	1.44	0.89	0.67
carnitine	ME537179	0.69	1.42	1.25	0.65
guanidinoacetate	ME537239	0.91	1.35	1.12	0.63
N-acetylhistidine	ME537266	0.95	1.33	1.09	0.62
cyclic AMP	ME537202	0.88	1.28	1.16	0.68
glycylglycine	ME537236	0.86	1.34	1.16	0.64
hypotaurine	ME537245	0.93	1.44	1.00	0.62
beta-alanine	ME537177	0.88	1.51	1.02	0.59
S-adenosylhomocysteine	ME537290	0.83	1.53	1.02	0.63
carnitine C14:1	ME537181	0.82	1.48	1.08	0.62
uridine	ME537308	0.87	1.45	1.04	0.65
glycerol 3-phosphate	ME537232	0.96	1.58	0.72	0.74
inositol	ME537248	0.79	1.61	0.83	0.77
N-acetylhexosamine phosphate	ME537265	0.81	1.54	0.94	0.72
carnitine C2	ME537184	1.04	1.86	0.66	0.44
carnitine C6	ME537188	0.91	1.76	0.75	0.59
orotate	ME537276	0.90	1.85	0.65	0.60
UMP	ME537306	0.82	1.84	0.70	0.64
sarcosine	ME537293	1.17	1.67	0.89	0.26
guanosine	ME537240	0.85	1.77	0.90	0.48
Glycerylphosphorylethanolamine	ME537234	1.02	1.62	0.99	0.38
glucose 6-phosphate	ME537226	1.02	1.53	0.89	0.55
deoxycarnitine	ME537209	1.01	1.67	0.81	0.51
uric acid	ME537307	0.96	1.63	0.88	0.53
4-hydroxyphenylpyruvate	ME537161	1.50	1.15	0.71	0.64
Coenzyme A	ME537197	1.45	1.26	0.85	0.45
N-acetylarginine	ME537261	1.25	1.38	0.65	0.71
cysteinylglycine	ME537205	1.35	1.44	0.50	0.71
glutathione reduced	ME537230	1.28	1.43	0.56	0.73
citicoline	ME537192	1.35	1.45	0.82	0.38
NADP	ME537271	1.42	1.51	0.65	0.43
glyceraldehyde 3-phosphate	ME537231	1.41	1.60	0.72	0.27
lactate	ME537253	1.31	1.62	0.72	0.36
pantothenate	ME537279	1.18	1.63	0.67	0.51
IMP	ME537246	1.23	1.64	0.57	0.55
N6,N6,N6-trimethyllysine	ME537260	1.28	1.62	0.60	0.50
oxidized glutathione	ME537278	1.27	1.43	0.69	0.61
ADP-ribose	ME537169	1.28	1.49	0.67	0.57
glucuronate	ME537227	1.23	1.51	0.68	0.58
fructose bisphosphate	ME537216	1.17	1.43	0.88	0.52
dihydroorotate	ME537210	1.26	1.47	0.79	0.48
GDP-fucose	ME537222	1.17	1.55	0.77	0.51

Factors:

F1	Genotype:Fh1-/- CL1 \| Treatment:Cas9
F2	Genotype:Fh1-/- CL1 \| Treatment:sg1Hira
F3	Genotype:Fh1 fl/fl \| Treatment:Cas9
F4	Genotype:Fh1 fl/fl \| Treatment:sg1Hira

Data matrix