Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for (Study ST002220)

(Analysis AN003629)

Metabolite	Structure	F1	F2	F3	F4
N-acetylaspartate_m+0	ME537426	0.13	0.15	0.30	3.43
N-acetylaspartate_m+1	ME537427	0.13	0.16	0.31	3.41
N-acetylaspartylglutamate	ME537430	0.02	0.02	0.05	3.91
phosphocreatine	ME537442	0.09	0.02	0.01	3.88
adenine	ME537328	0.82	0.69	0.38	2.11
N-acetylglutamate	ME537431	0.64	0.55	0.61	2.20
serine	ME537459	0.58	0.65	0.49	2.27
phosphorylcholine	ME537444	0.43	0.49	0.56	2.52
dihydroorotate	ME537375	0.38	0.77	0.42	2.42
N-carbamoylaspartate	ME537435	0.65	0.63	0.21	2.51
orotate	ME537437	0.47	0.73	0.24	2.56
glucose	ME537384	0.52	1.11	0.48	1.89
carnitine C16	ME537344	0.85	0.52	0.67	1.97
succinate	ME537462	0.61	0.83	0.65	1.91
betaine	ME537341	0.67	0.69	0.71	1.93
carnitine C14	ME537343	0.70	0.64	0.72	1.95
threonine	ME537464	0.83	0.85	0.73	1.60
S-Succinylglutathione	ME537461	0.86	0.70	0.61	1.83
4-hydroxyproline	ME537322	0.71	0.82	0.68	1.78
alanine	ME537331	0.78	0.77	0.70	1.74
N-acetylaspartate_m+2	ME537428	0.75	1.40	1.62	0.04
N-acetylaspartate_m+3	ME537429	0.35	1.07	1.58	NA
aconitate_m+3	ME537327	1.64	0.86	0.50	NA
fumarate_m+2	ME537380	1.46	1.08	0.77	0.23
fumarate_m+3	ME537381	1.43	0.86	0.71	NA
carnitine C5_m+6	ME537363	1.26	1.13	0.61	NA
aconitate_m+2	ME537326	1.31	0.98	0.71	NA
citrate_m+2	ME537367	1.26	1.03	0.71	NA
citrate_m+3	ME537368	1.24	1.00	0.76	NA
2-hydroxyglutarate_m+3	ME537316	0.75	1.20	1.00	NA
2-oxoglutarate_m+3	ME537320	0.91	1.15	0.94	NA
carnitine C5_m+3	ME537360	0.91	1.44	0.56	NA
glutathione reduced_m+3	ME537395	0.93	1.58	0.48	NA
aspartate_m+3	ME537339	1.09	1.22	0.70	NA
proline_m+3	ME537448	0.97	1.33	0.70	NA
carnitine C18	ME537345	1.34	1.07	1.31	0.29
hypotaurine	ME537406	1.04	1.14	1.22	0.60
Inositol	ME537409	1.13	1.05	1.29	0.54
taurine	ME537463	1.13	1.10	1.25	0.52
carnitine C4_m+3	ME537357	1.25	1.73	0.62	0.24
pyroglutamate_m+2	ME537451	1.06	1.62	0.91	0.42
carnitine C4_m+2	ME537356	1.39	1.39	0.81	0.40
guanosine	ME537402	1.34	1.15	0.97	0.55
S-lactoylglutathione	ME537460	1.35	1.21	0.95	0.49
2-hydroxyglutarate_m+2	ME537315	1.13	1.51	1.19	0.17
2-oxoglutarate_m+2	ME537319	1.32	1.53	1.11	0.04
glutathione reduced_m+2	ME537394	1.25	1.67	0.98	0.10
carnitine C3_m+3	ME537353	1.55	1.51	0.80	0.14
carnitine C5_m+4	ME537361	1.61	1.49	0.82	0.07
aspartate_m+2	ME537338	1.39	1.53	0.89	0.19
carnitine C3_m+2	ME537352	1.47	1.58	0.77	0.18
carnitine C2_m+2	ME537349	1.51	1.28	1.06	0.16
malate_m+3	ME537424	1.46	1.37	1.12	0.05
carnitine C5_m+5	ME537362	1.44	1.34	0.89	0.17
S-adenosylmethionine_m+2	ME537457	1.42	1.41	0.97	0.20
glutamate_m+2	ME537387	1.31	1.39	1.07	0.23
malate_m+2	ME537423	1.33	1.29	1.07	0.31
adenosine	ME537329	0.70	0.73	1.16	1.41
deoxycarnitine	ME537374	0.96	0.86	1.04	1.14
glyceraldehyde 3-phosphate	ME537396	1.13	0.83	1.08	0.97
ornithine	ME537436	0.99	0.92	1.08	1.00
S-(2-succinyl)cysteine	ME537453	1.04	0.86	1.10	1.00
cystathionine	ME537373	1.04	0.60	1.04	1.32
palmitate	ME537439	1.11	0.76	0.88	1.25
CTP	ME537372	1.32	0.84	0.74	1.11
UMP	ME537470	1.17	0.91	0.80	1.12
ATP	ME537340	1.25	0.89	0.77	1.09
CDP	ME537364	1.22	0.85	0.80	1.12
UDP	ME537467	1.08	0.98	0.66	1.27
UTP	ME537471	1.19	0.93	0.67	1.21
carnitine C3_m+0	ME537350	0.95	0.90	0.68	1.46
carnitine C3_m+1	ME537351	0.96	0.92	0.68	1.44
CMP-acetylneuraminate	ME537370	0.98	0.90	0.78	1.33
proline_m+0	ME537445	0.96	0.92	0.79	1.34
proline_m+1	ME537446	0.96	0.93	0.79	1.32
hypoxanthine	ME537407	0.88	1.01	0.90	1.22
carnitine C18:1	ME537346	0.93	0.91	0.91	1.26
fumarate_m+1	ME537379	1.02	0.92	0.91	1.15
malate_m+1	ME537422	1.01	0.93	0.91	1.15
fumarate_m+0	ME537378	1.00	0.90	0.87	1.23
malate_m+0	ME537421	1.00	0.91	0.89	1.20
carnitine C4_m+0	ME537354	1.02	1.00	0.80	1.19
carnitine C4_m+1	ME537355	1.03	1.01	0.79	1.17
creatine	ME537371	0.99	1.07	0.79	1.14
UDP-GlcNac	ME537468	1.03	1.05	0.80	1.12
Asparagine	ME537335	0.97	0.97	0.83	1.23
GDP fucose	ME537383	1.07	0.93	0.80	1.21
oxidized glutathione	ME537438	1.04	0.94	0.77	1.24
UDP-glucose	ME537469	1.02	0.96	0.79	1.23
inosine	ME537408	0.89	1.19	0.91	1.01
pyroglutamate_m+0	ME537449	0.98	1.17	0.80	1.05
pyroglutamate_m+1	ME537450	0.97	1.17	0.82	1.04
aspartate_m+0	ME537336	1.08	1.14	0.81	0.97
aspartate_m+1	ME537337	1.10	1.16	0.81	0.92
fructose bisphosphate	ME537377	1.10	1.09	0.75	1.06
S-adenosylhomocysteine	ME537454	1.11	1.03	0.76	1.09
glutamate_m+3	ME537388	1.08	1.11	0.94	0.86
leucine+isoleucine_m+5	ME537418	1.09	1.11	0.93	0.86
leucine+isoleucine_m+6	ME537419	1.09	1.11	0.93	0.87
glutamate_m+0	ME537385	1.08	1.04	0.97	0.90
glutamate_m+1	ME537386	1.09	1.05	0.98	0.87
citrulline	ME537369	1.05	1.05	0.99	0.91
histidine	ME537404	1.02	1.08	1.00	0.90
kynurenine	ME537413	1.06	1.07	1.04	0.83
2-hydroxyglutarate_m+0	ME537313	0.99	1.10	1.09	0.82
2-hydroxyglutarate_m+1	ME537314	0.99	1.11	1.09	0.80
AMP	ME537332	1.16	0.97	0.90	0.97
carnitine C2_m+0	ME537347	1.15	0.93	0.94	0.97
carnitine C2_m+1	ME537348	1.16	0.93	0.94	0.98
methionine	ME537425	0.99	1.04	0.98	0.99
NAD	ME537433	1.08	0.99	0.94	0.99
glutathione reduced_m+0	ME537392	1.06	1.04	0.88	1.02
glutathione reduced_m+1	ME537393	1.06	1.05	0.88	1.01
ketoleucine+ketoisoleucine_m+5	ME537411	0.97	1.31	1.00	0.71
ketoleucine+ketoisoleucine_m+6	ME537412	1.01	1.23	1.02	0.75
glycerate	ME537397	0.98	1.24	0.84	0.93
glutamine_m+2	ME537391	1.03	1.26	0.88	0.83
glutamine_m+0	ME537389	1.03	1.25	0.90	0.83
glutamine_m+1	ME537390	1.03	1.25	0.90	0.83
aconitate_m+0	ME537324	1.23	1.01	1.03	0.72
aconitate_m+1	ME537325	1.27	1.03	1.04	0.66
arginine	ME537333	1.21	0.91	1.03	0.85
carnitine	ME537342	1.10	0.99	1.11	0.80
lysine	ME537420	1.16	1.01	1.08	0.75
homocitrulline	ME537405	1.24	1.11	0.86	0.79
citrate_m+0	ME537365	1.18	1.05	0.94	0.83
citrate_m+1	ME537366	1.21	1.06	0.94	0.79
2-oxoglutarate_m+1	ME537318	1.11	1.16	1.05	0.69
S-adenosylmethionine_m+1	ME537456	1.12	1.16	1.05	0.67
2-oxoglutarate_m+0	ME537317	1.10	1.14	1.04	0.71
ketoleucine+ketoisoleucine_m+0	ME537410	1.12	1.15	1.02	0.71
S-adenosylmethionine_m+0	ME537455	1.11	1.15	1.03	0.71
leucine+isoleucine_m+1	ME537416	1.15	1.15	1.01	0.69
valine	ME537472	1.12	1.19	1.01	0.69
tyrosine	ME537466	1.16	1.15	0.92	0.77
tryptophan	ME537465	1.17	1.13	0.97	0.73
leucine+isoleucine_m+0	ME537415	1.14	1.12	0.98	0.76
phenylalanine	ME537441	1.13	1.10	0.99	0.77
proline_m+2	ME537447	1.18	1.27	0.84	0.71
glycerylphosphorylcholine	ME537399	1.07	1.25	0.96	0.72
leucine+isoleucine_m+4	ME537417	1.13	1.23	0.92	0.72
glycerol 3-phosphate	ME537398	1.16	1.27	0.97	0.59
carnitine C5_m+0	ME537358	1.22	1.17	0.90	0.71
carnitine C5_m+1	ME537359	1.26	1.19	0.93	0.62
GDP	ME537382	1.40	0.77	0.88	0.96
ADP	ME537330	1.38	0.89	0.82	0.91
GTP	ME537401	1.47	0.83	0.77	0.92
phosphoenolpyruvate	ME537443	1.32	1.01	0.49	1.17
dihydroxyacetone phosphate	ME537376	1.29	1.05	0.76	0.90
2/3-phosphoglycerate	ME537321	1.25	1.10	0.60	1.04
N-acetylneuraminic acid	ME537432	1.22	1.22	0.59	0.98
6-phosphogluconate	ME537323	0.43	1.44	0.65	1.49
xanthine	ME537473	0.76	1.18	0.63	1.42
glycine	ME537400	0.92	0.97	0.56	1.56
pentose phosphate	ME537440	0.86	1.07	0.57	1.51
hexose phosphate	ME537403	0.72	1.35	0.99	0.94
sedoheptulose 7-phosphate	ME537458	0.79	1.45	0.65	1.10
lactate	ME537414	0.94	1.22	0.69	1.16
pyruvate	ME537452	0.86	1.22	0.73	1.19
argininosuccinate	ME537334	1.75	1.44	0.01	0.80
NADH	ME537434	1.84	0.54	0.52	1.10

Factors:

F1	Cell line:786-M1A \| Treatment:13C6-leucine+13C6-isoleucine
F2	Cell line:786-M2A \| Treatment:13C6-leucine+13C6-isoleucine
F3	Cell line:786-O \| Treatment:13C6-leucine+13C6-isoleucine
F4	Cell line:HK2 \| Treatment:13C6-leucine+13C6-isoleucine

Data matrix